메뉴 건너뛰기




Volumn 13, Issue 1, 2014, Pages

Exenatide can inhibit calcification of human VSMCs through the NF-kappaB/RANKL signaling pathway

Author keywords

Arterial calcification; Diabetes; Glucagon like peptide 1; Osteoblastic differentiation; Vascular smooth muscle cells

Indexed keywords

ALKALINE PHOSPHATASE; CALCITRIOL; EXENDIN 4; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; GLYCEROL 2 PHOSPHATE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OSTEOCALCIN; OSTEOCLAST DIFFERENTIATION FACTOR; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RUNX2; GLP1R PROTEIN, HUMAN; GLUCAGON RECEPTOR; PEPTIDE; VENOM;

EID: 84964695725     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/s12933-014-0153-4     Document Type: Article
Times cited : (34)

References (42)
  • 2
    • 0347133334 scopus 로고    scopus 로고
    • Poor control of risk factors for vascular disease among adults with previously diagnosed diabetes
    • Saydah SH, Fradkin J, Cowie CC: Poor control of risk factors for vascular disease among adults with previously diagnosed diabetes. JAMA 2004, 291:335-342.
    • (2004) JAMA , vol.291 , pp. 335-342
    • Saydah, S.H.1    Fradkin, J.2    Cowie, C.C.3
  • 3
    • 84890118673 scopus 로고    scopus 로고
    • Anti-diabetic actions of glucagon-like peptide-1 on pancreatic beta-cells
    • Lee YS, Jun HS: Anti-diabetic actions of glucagon-like peptide-1 on pancreatic beta-cells. Metabolism 2014, 63:9-19.
    • (2014) Metabolism , vol.63 , pp. 9-19
    • Lee, Y.S.1    Jun, H.S.2
  • 5
    • 33846006173 scopus 로고    scopus 로고
    • The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
    • Drucker DJ, Nauck MA: The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes. Lancet 2006, 368:1696-1705.
    • (2006) Lancet , vol.368 , pp. 1696-1705
    • Drucker, D.J.1    Nauck, M.A.2
  • 6
    • 84875178118 scopus 로고    scopus 로고
    • Treatment of patients with type 2 diabetes with exenatide once weekly versus oral glucose-lowering medications or insulin glargine: achievement of glycemic and cardiovascular goals
    • Meloni AR, DeYoung MB, Han J, Best JH, Grimm M: Treatment of patients with type 2 diabetes with exenatide once weekly versus oral glucose-lowering medications or insulin glargine: achievement of glycemic and cardiovascular goals. Cardiovasc Diabetol 2013, 12:48.
    • (2013) Cardiovasc Diabetol , vol.12 , pp. 48
    • Meloni, A.R.1    DeYoung, M.B.2    Han, J.3    Best, J.H.4    Grimm, M.5
  • 7
    • 84920046998 scopus 로고    scopus 로고
    • Dynamic risk factors associated with non-severe hypoglycaemia in patients treated with insulin glargine or exenatide once weekly
    • Paul SK, Maggs D, Klein K, Best JH: Dynamic risk factors associated with non-severe hypoglycaemia in patients treated with insulin glargine or exenatide once weekly. J Diabetes 2014, doi: 10.1111/1753-0407.12208.
    • (2014) J Diabetes
    • Paul, S.K.1    Maggs, D.2    Klein, K.3    Best, J.H.4
  • 8
    • 40749161446 scopus 로고    scopus 로고
    • Exenatide as a treatment for diabetes and obesity: implications for cardiovascular risk reduction
    • Mafong DD, Henry RR: Exenatide as a treatment for diabetes and obesity: implications for cardiovascular risk reduction. Curr Atheroscler Rep 2008, 10:55-60.
    • (2008) Curr Atheroscler Rep , vol.10 , pp. 55-60
    • Mafong, D.D.1    Henry, R.R.2
  • 10
    • 77951666601 scopus 로고    scopus 로고
    • Liao EY:Connective tissue growth factor is a down stream mediator for preptin-induced proliferation and differentiation in human osteoblasts
    • Liu YS, Lu Y, Liu W, Xie H, Luo XH, Wu XP, Yuan LQ: Liao EY:Connective tissue growth factor is a down stream mediator for preptin-induced proliferation and differentiation in human osteoblasts. Amino Acids 2010, 38:763-769.
    • (2010) Amino Acids , vol.38 , pp. 763-769
    • Liu, Y.S.1    Lu, Y.2    Liu, W.3    Xie, H.4    Luo, X.H.5    Wu, X.P.6    Yuan, L.Q.7
  • 14
    • 84899957532 scopus 로고    scopus 로고
    • The mammalian target of rapamycin signalling pathway is involved in osteoblastic differentiation of vascular smooth muscle cells
    • Zhan JK, Wang YJ, Wang Y, Wang S, Tan P, Huang W, Liu YS: The mammalian target of rapamycin signalling pathway is involved in osteoblastic differentiation of vascular smooth muscle cells. Can J Cardiol 2014, 30:568-575.
    • (2014) Can J Cardiol , vol.30 , pp. 568-575
    • Zhan, J.K.1    Wang, Y.J.2    Wang, Y.3    Wang, S.4    Tan, P.5    Huang, W.6    Liu, Y.S.7
  • 15
    • 84897499323 scopus 로고    scopus 로고
    • Adiponectin attenuates the osteoblastic differentiation of vascular smooth muscle cells through the AMPK/mTOR pathway
    • Zhan JK, Wang YJ, Wang Y, Tang ZY, Tan P, Huang W, Liu YS: Adiponectin attenuates the osteoblastic differentiation of vascular smooth muscle cells through the AMPK/mTOR pathway. Exp Cell Res 2014, 323:352-358.
    • (2014) Exp Cell Res , vol.323 , pp. 352-358
    • Zhan, J.K.1    Wang, Y.J.2    Wang, Y.3    Tang, Z.Y.4    Tan, P.5    Huang, W.6    Liu, Y.S.7
  • 17
    • 0035824898 scopus 로고    scopus 로고
    • Smooth muscle cell phenotypic transition associated with calcification upregulation of cbfa1 and downregulation of smooth muscle lineage markers
    • Steitz SA, Speer MY, Curinga G, Yang HY, Haynes P, Aebersold R, Schinke T, Karsenty G, Giachelli CM: Smooth muscle cell phenotypic transition associated with calcification upregulation of cbfa1 and downregulation of smooth muscle lineage markers. Circ Res 2001, 89:1147-1154.
    • (2001) Circ Res , vol.89 , pp. 1147-1154
    • Steitz, S.A.1    Speer, M.Y.2    Curinga, G.3    Yang, H.Y.4    Haynes, P.5    Aebersold, R.6    Schinke, T.7    Karsenty, G.8    Giachelli, C.M.9
  • 18
    • 78649768163 scopus 로고    scopus 로고
    • Selenium suppressed hydrogen peroxide-induced vascular smooth muscle cells calcification through inhibiting oxidative stress and ERK activation
    • Liu H, Lu Q, Huang K: Selenium suppressed hydrogen peroxide-induced vascular smooth muscle cells calcification through inhibiting oxidative stress and ERK activation. J Cell Biochem 2010, 111:1556-1564.
    • (2010) J Cell Biochem , vol.111 , pp. 1556-1564
    • Liu, H.1    Lu, Q.2    Huang, K.3
  • 19
    • 0842283932 scopus 로고    scopus 로고
    • Novel aspects on RANK ligand and osteoprotegerin in osteoporosis and vascular disease
    • Sattler AM, Schoppet M, Schaefer JR, Hofbauer LC: Novel aspects on RANK ligand and osteoprotegerin in osteoporosis and vascular disease. Calcif Tissue Int 2004, 74:103-106.
    • (2004) Calcif Tissue Int , vol.74 , pp. 103-106
    • Sattler, A.M.1    Schoppet, M.2    Schaefer, J.R.3    Hofbauer, L.C.4
  • 25
    • 79952779707 scopus 로고    scopus 로고
    • Apelin attenuates the osteoblastic differentiation of vascular smooth muscle cells
    • Shan PF, Lu Y, Cui RR, Jiang Y, Yuan LQ, Liao EY: Apelin attenuates the osteoblastic differentiation of vascular smooth muscle cells. PLoS One 2011, 6:e17938.
    • (2011) PLoS One , vol.6
    • Shan, P.F.1    Lu, Y.2    Cui, R.R.3    Jiang, Y.4    Yuan, L.Q.5    Liao, E.Y.6
  • 27
    • 33744496521 scopus 로고    scopus 로고
    • Protein-tyrosine kinase Sykis required for pathogen engulfment in complement-mediated phagocytosis
    • Shi Y, Tohyama Y, Kadono T, He J, Miah SM, Hazama R, Tanaka C, Tohyama K, Yamamura H: Protein-tyrosine kinase Sykis required for pathogen engulfment in complement-mediated phagocytosis. Blood 2006, 107:4554-4562.
    • (2006) Blood , vol.107 , pp. 4554-4562
    • Shi, Y.1    Tohyama, Y.2    Kadono, T.3    He, J.4    Miah, S.M.5    Hazama, R.6    Tanaka, C.7    Tohyama, K.8    Yamamura, H.9
  • 28
    • 84895932629 scopus 로고    scopus 로고
    • Increased Calcification in Osteoprotegerin-Deficient Smooth Muscle Cells: Dependence on Receptor Activator of NF-κB Ligand and Interleukin 6
    • Callegari A, Coons ML, Ricks JL, Rosenfeld ME, Scatena M: Increased Calcification in Osteoprotegerin-Deficient Smooth Muscle Cells: Dependence on Receptor Activator of NF-κB Ligand and Interleukin 6. J Vasc Res 2014, 51:118-131.
    • (2014) J Vasc Res , vol.51 , pp. 118-131
    • Callegari, A.1    Coons, M.L.2    Ricks, J.L.3    Rosenfeld, M.E.4    Scatena, M.5
  • 30
    • 0036721615 scopus 로고    scopus 로고
    • 1,25(OH)2 vitamin D3-stimulated osteoclast formation in spleen-osteoblast cocultures is mediated in part by enhanced IL-1 alpha and receptor activator of NF-kappa B ligand production in osteoblasts
    • Lee SK, Kalinowski J, Jastrzebski S, Lorenzo JA: 1,25(OH)2 vitamin D3-stimulated osteoclast formation in spleen-osteoblast cocultures is mediated in part by enhanced IL-1 alpha and receptor activator of NF-kappa B ligand production in osteoblasts. J Immunol 2002, 169:2374-2380.
    • (2002) J Immunol , vol.169 , pp. 2374-2380
    • Lee, S.K.1    Kalinowski, J.2    Jastrzebski, S.3    Lorenzo, J.A.4
  • 31
    • 0037283601 scopus 로고    scopus 로고
    • The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes
    • Kahn SE: The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes. Diabetologia 2003, 46:3-19.
    • (2003) Diabetologia , vol.46 , pp. 3-19
    • Kahn, S.E.1
  • 33
    • 84927174916 scopus 로고    scopus 로고
    • Retrospective cohort study evaluating exenatide twice daily and long-acting insulin analogs in a Veterans Health Administration population with type 2 diabetes
    • Bounthavong M, Tran JN, Golshan S, Piland NF, Morello CM, Blickensderfer A, Best JH: Retrospective cohort study evaluating exenatide twice daily and long-acting insulin analogs in a Veterans Health Administration population with type 2 diabetes. Diabetes Metab 2014, 40:284-291.
    • (2014) Diabetes Metab , vol.40 , pp. 284-291
    • Bounthavong, M.1    Tran, J.N.2    Golshan, S.3    Piland, N.F.4    Morello, C.M.5    Blickensderfer, A.6    Best, J.H.7
  • 34
    • 84861944029 scopus 로고    scopus 로고
    • Effects of exenatide vs metformin on endothelial function in obese patients with pre-diabetes: a randomized trial
    • Kelly AS, Bergenstal RM, Gonzalez-Campoy JM, Katz H, Bank AJ: Effects of exenatide vs metformin on endothelial function in obese patients with pre-diabetes: a randomized trial. Cardiovasc Diabetol 2012, 11:64.
    • (2012) Cardiovasc Diabetol , vol.11 , pp. 64
    • Kelly, A.S.1    Bergenstal, R.M.2    Gonzalez-Campoy, J.M.3    Katz, H.4    Bank, A.J.5
  • 35
    • 83255176860 scopus 로고    scopus 로고
    • Beyond glucose lowering: glucagon-like peptide-1 receptor agonists, body weight and the cardiovascular system
    • Vergès B, Bonnard C, Renard E: Beyond glucose lowering: glucagon-like peptide-1 receptor agonists, body weight and the cardiovascular system. Diabetes Metab 2011, 37:477-488.
    • (2011) Diabetes Metab , vol.37 , pp. 477-488
    • Vergès, B.1    Bonnard, C.2    Renard, E.3
  • 36
    • 12144260853 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 can directly protect the heart against ischemia/reperfusion injury
    • Bose AK, Mocanu MM, Carr RD, Brand CL, Yellon DM: Glucagon-like peptide 1 can directly protect the heart against ischemia/reperfusion injury. Diabetes 2005, 54:146-151.
    • (2005) Diabetes , vol.54 , pp. 146-151
    • Bose, A.K.1    Mocanu, M.M.2    Carr, R.D.3    Brand, C.L.4    Yellon, D.M.5
  • 37
    • 77951151612 scopus 로고    scopus 로고
    • Inhibition of monocyte adhesion to endothelial cells and attenuation of atherosclerotic lesion by a glucagonlike peptide-1 receptor agonist, exendin-4
    • Arakawa M, Mita T, Azuma K, Ebato C, Goto H, Nomiyama T, Fujitani Y, Hirose T, Kawamori R, Watada H: Inhibition of monocyte adhesion to endothelial cells and attenuation of atherosclerotic lesion by a glucagonlike peptide-1 receptor agonist, exendin-4. Diabetes 2010, 59:1030-1037.
    • (2010) Diabetes , vol.59 , pp. 1030-1037
    • Arakawa, M.1    Mita, T.2    Azuma, K.3    Ebato, C.4    Goto, H.5    Nomiyama, T.6    Fujitani, Y.7    Hirose, T.8    Kawamori, R.9    Watada, H.10
  • 41
    • 84879557615 scopus 로고    scopus 로고
    • Oxidized low density lipoprotein enhanced RANKL expression in human osteoblast-like cells. Involvement of ERK, NFkappaB and NFAT
    • Mazière C, Salle V, Gomila C, Mazière JC: Oxidized low density lipoprotein enhanced RANKL expression in human osteoblast-like cells. Involvement of ERK, NFkappaB and NFAT. Biochim Biophys Acta 2013, 1832:1756-1764.
    • (2013) Biochim Biophys Acta , vol.1832 , pp. 1756-1764
    • Mazière, C.1    Salle, V.2    Gomila, C.3    Mazière, J.C.4
  • 42
    • 36049045123 scopus 로고    scopus 로고
    • Hypo-phosphorylation leads to nuclear retention of NF-κB p65 due to impaired IκBα gene synthesis
    • Hochrainer K, Racchumia G, Anrather J: Hypo-phosphorylation leads to nuclear retention of NF-κB p65 due to impaired IκBα gene synthesis. FEBS Lett 2007, 581:5493-5499.
    • (2007) FEBS Lett , vol.581 , pp. 5493-5499
    • Hochrainer, K.1    Racchumia, G.2    Anrather, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.