Defining actionable mutations for oncology therapeutic development

Nature Reviews Cancer

Volumn 16, Issue 5, 2016, Pages 319-329

  Carr, T Hedley ^a   McEwen, Robert ^a   Dougherty, Brian ^a   Johnson, Justin H ^a   Dry, Jonathan R ^a   Lai, Zhongwu ^a   Ghazoui, Zara ^a   Laing, Naomi M ^a   Hodgson, Darren R ^a   Cruzalegui, Francisco ^a   Hollingsworth, Simon J ^a   Barrett, J Carl ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; NEW DRUG; 2 ALLYL 1 [6 (1 HYDROXY 1 METHYLETHYL) 2 PYRIDINYL] 6 [4 (4 METHYL 1 PIPERAZINYL)ANILINO] 1H PYRAZOLO[3,4 D]PYRIMIDIN 3(2H) ONE; PROTEIN P53; PYRAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE;

CANCER PATIENT; GENE FUNCTION; GENE MUTATION; GENOMICS; HUMAN; MARKER GENE; MOLECULARLY TARGETED THERAPY; ONCOLOGIST; ONCOLOGY; PRIORITY JOURNAL; RAPID TEST; REVIEW; TREATMENT RESPONSE; CARCINOMA, NON-SMALL-CELL LUNG; GENETICS; LUNG NEOPLASMS; MUTATION;

CARCINOMA, NON-SMALL-CELL LUNG; HUMANS; LUNG NEOPLASMS; MUTATION; PYRAZOLES; PYRIMIDINES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84964691672     PISSN: 1474175X     EISSN: 14741768     Source Type: Journal    
DOI: 10.1038/nrc.2016.35     Document Type: Review

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