Size-Limited Penetration of Nanoparticles into Porcine Respiratory Mucus after Aerosol Deposition

Biomacromolecules

Volumn 17, Issue 4, 2016, Pages 1536-1542

  Murgia, Xabier ^a   Pawelzyk, Paul ^c   Schaefer, Ulrich F ^b   Wagner, Christian ^b   Willenbacher, Norbert ^c   Lehr, Claus Michael ^a,b  

^a SAARLAND UNIVERSITY   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AEROSOLS; DEPOSITION; NANOPARTICLES; RESPIRATORY MECHANICS;

AEROSOL DEPOSITION; AEROSOL PARTICLES; MECHANICAL DISPERSION; MUCUS LAYER; PULMONARY DRUG DELIVERY; RHEOLOGICAL PROPERTY; TIME-SCALES; TRACER PARTICLE;

BODY FLUIDS;

CARBOXYLATED POLYSTYRENE NANOPARTICLE; MUCIN; NANOPARTICLE; POLYSTYRENE DERIVATIVE; UNCLASSIFIED DRUG; VISCOELASTIC SUBSTANCE; AEROSOL; DRUG CARRIER;

AEROSOL; ANIMAL TISSUE; ARTICLE; CHEMICAL INTERACTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIFFUSION; DIFFUSION COEFFICIENT; DISPERSION; FLOW KINETICS; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; HYDROPHOBICITY; MATHEMATICAL PARAMETERS; MEASUREMENT ERROR; MICROENVIRONMENT; MUCOADHESION; MUCOPENETRATION; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; TIME; TISSUE STRUCTURE; TRACHEA MUCUS; VISCOELASTICITY; VISCOSITY; ANIMAL; CYTOLOGY; DRUG EFFECTS; LUNG; METABOLISM; MUCUS; PIG; RESPIRATORY MUCOSA; TRANSPORT AT THE CELLULAR LEVEL;

AEROSOLS; ANIMALS; BIOLOGICAL TRANSPORT; DRUG CARRIERS; LUNG; MUCUS; NANOPARTICLES; PARTICLE SIZE; RESPIRATORY MUCOSA; RHEOLOGY; SWINE;

EID: 84964688276     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/acs.biomac.6b00164     Document Type: Article

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