PI3-kinase mutation linked to insulin and growth factor resistance in vivo

Journal of Clinical Investigation

Volumn 126, Issue 4, 2016, Pages 1401-1412

  Winnay, Jonathon N ^a   Solheim, Marie H ^a,b   Dirice, Ercument ^a   Sakaguchi, Masaji ^a   Noh, Hye Lim ^c   Kang, Hee Joon ^c   Takahashi, Hirokazu ^a   Chudasama, Kishan K ^b,d   Kim, Jason K ^c   Molven, Anders ^b,e   Kahn, C Ronald ^a   Njølstad, Pal R ^b,e  

^a JOSLIN DIABETES CENTER   (United States)

^b UNIVERSITY OF BERGEN   (Norway)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^d OSLO UNIVERSITY HOSPITAL   (Norway)

^e HAUKELAND UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; GROWTH FACTOR; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; INSULIN; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR; VASCULOTROPIN RECEPTOR; GROWTH HORMONE;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY HEIGHT; BODY WEIGHT; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEMALE; GENE MUTATION; GENE REARRANGEMENT; GENE SILENCING; GENETIC ASSOCIATION; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLUCOSE TOLERANCE TEST; GLUCOSE TRANSPORT; GROWTH RETARDATION; HETEROZYGOSITY; HOMOZYGOSITY; HYPERINSULINEMIC-EUGLYCEMIC CLAMP TECHNIQUE; IN VITRO STUDY; IN VIVO STUDY; INSULIN RELEASE; INSULIN RESISTANCE; LIPODYSTROPHY; MALE; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SHORT STATURE; SIGNAL TRANSDUCTION; AMINO ACID SUBSTITUTION; ANIMAL; ENZYMOLOGY; GENETICS; LIVER; METABOLISM; MISSENSE MUTATION; MUTANT MOUSE STRAIN; PATHOLOGY; SECRETION (PROCESS);

AMINO ACID SUBSTITUTION; ANIMALS; GLUCAGON-LIKE PEPTIDE 1; GROWTH HORMONE; INSULIN; INSULIN RESISTANCE; LIPODYSTROPHY; LIVER; MICE; MICE, MUTANT STRAINS; MUTATION, MISSENSE; PHOSPHATIDYLINOSITOL 3-KINASES;

EID: 84964608729     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI84005     Document Type: Article

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