-
1
-
-
28544446111
-
Monocyte and macrophage heterogeneity
-
Gordon S, Taylor PR. Monocyte and macrophage heterogeneity. Nat Rev Immunol. 2005;5(12):953-964.
-
(2005)
Nat Rev Immunol.
, vol.5
, Issue.12
, pp. 953-964
-
-
Gordon, S.1
Taylor, P.R.2
-
2
-
-
80355146399
-
Transcriptional regulation of macrophage polarization: Enabling diversity with identity
-
Lawrence T, Natoli G. Transcriptional regulation of macrophage polarization: enabling diversity with identity. Nat Rev Immunol. 2011;11(11):750-761.
-
(2011)
Nat Rev Immunol.
, vol.11
, Issue.11
, pp. 750-761
-
-
Lawrence, T.1
Natoli, G.2
-
3
-
-
84871076444
-
Macrophage plasticity and polarization in tissue repair and remodelling
-
Mantovani A, Biswas SK, Galdiero MR, Sica A, Locati M. Macrophage plasticity and polarization in tissue repair and remodelling. J Pathol. 2012;229(2):176-185.
-
(2012)
J Pathol.
, vol.229
, Issue.2
, pp. 176-185
-
-
Mantovani, A.1
Biswas, S.K.2
Galdiero, M.R.3
Sica, A.4
Locati, M.5
-
4
-
-
80355131976
-
Protective and pathogenic functions of macrophage subsets
-
Murray PJ, Wynn TA. Protective and pathogenic functions of macrophage subsets. Nat Rev Immunol. 2011;11(11):723-737.
-
(2011)
Nat Rev Immunol.
, vol.11
, Issue.11
, pp. 723-737
-
-
Murray, P.J.1
Wynn, T.A.2
-
5
-
-
77956976681
-
Macrophage plasticity and interaction with lymphocyte subsets: Cancer as a paradigm
-
Biswas SK, Mantovani A. Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nat Immunol. 2010;11(10):889-896.
-
(2010)
Nat Immunol.
, vol.11
, Issue.10
, pp. 889-896
-
-
Biswas, S.K.1
Mantovani, A.2
-
6
-
-
71649091697
-
Alternatively activated macrophages in infection and autoimmunity
-
Fairweather D, Cihakova D. Alternatively activated macrophages in infection and autoimmunity. J Autoimmun. 2009;33(3-4):222-230.
-
(2009)
J Autoimmun.
, vol.33
, Issue.3-4
, pp. 222-230
-
-
Fairweather, D.1
Cihakova, D.2
-
7
-
-
70349581878
-
Macrophage diversity and polarization in atherosclerosis: A question of balance
-
Mantovani A, Garlanda C, Locati M. Macrophage diversity and polarization in atherosclerosis: A question of balance. Arterioscler Thromb Vasc Biol. 2009;29(10):1419-1423.
-
(2009)
Arterioscler Thromb Vasc Biol.
, vol.29
, Issue.10
, pp. 1419-1423
-
-
Mantovani, A.1
Garlanda, C.2
Locati, M.3
-
8
-
-
80052757406
-
Phenotypic modulation of macrophages in response to plaque lipids
-
Adamson S, Leitinger N. Phenotypic modulation of macrophages in response to plaque lipids. Curr Opin Lipidol. 2011;22(5):335-342.
-
(2011)
Curr Opin Lipidol.
, vol.22
, Issue.5
, pp. 335-342
-
-
Adamson, S.1
Leitinger, N.2
-
9
-
-
77957260181
-
Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2
-
Kadl A, et al. Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2. Circ Res. 2010;107(6):737-746.
-
(2010)
Circ Res.
, vol.107
, Issue.6
, pp. 737-746
-
-
Kadl, A.1
-
10
-
-
33846026712
-
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
-
Lumeng CN, Bodzin JL, Saltiel AR. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest. 2007;117(1):175-184.
-
(2007)
J Clin Invest.
, vol.117
, Issue.1
, pp. 175-184
-
-
Lumeng, C.N.1
Bodzin, J.L.2
Saltiel, A.R.3
-
11
-
-
80355133234
-
Macrophagemediated inflammation in metabolic disease
-
Chawla A, Nguyen KD, Goh YPS. Macrophagemediated inflammation in metabolic disease. Nat Rev Immunol. 2011;11(11):738-749.
-
(2011)
Nat Rev Immunol.
, vol.11
, Issue.11
, pp. 738-749
-
-
Chawla, A.1
Nguyen, K.D.2
Goh, Y.P.S.3
-
12
-
-
45149134605
-
"Re-educating" tumor-associated macrophages by targeting NF-κB
-
Hagemann T, et al. "Re-educating" tumor-associated macrophages by targeting NF-κB. J Exp Med. 2008;205(6):1261-1268.
-
(2008)
J Exp Med.
, vol.205
, Issue.6
, pp. 1261-1268
-
-
Hagemann, T.1
-
13
-
-
7644231561
-
The chemokine system in diverse forms of macrophage activation and polarization
-
Mantovani A, Sica A, Sozzani S, Allavena P, Vecchi A, Locati M. The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol. 2004;25(12):677-686.
-
(2004)
Trends Immunol.
, vol.25
, Issue.12
, pp. 677-686
-
-
Mantovani, A.1
Sica, A.2
Sozzani, S.3
Allavena, P.4
Vecchi, A.5
Locati, M.6
-
14
-
-
38449102676
-
Macrophage activation and polarization
-
Martinez FO. Macrophage activation and polarization. Front Biosci. 2008;13(13):453.
-
(2008)
Front Biosci.
, vol.13
, Issue.13
, pp. 453
-
-
Martinez, F.O.1
-
15
-
-
17844386319
-
IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation
-
Lawrence T, Bebien M, Liu GY, Nizet V, Karin M. IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation. Nature. 2005;434(7037):1138-1143.
-
(2005)
Nature.
, vol.434
, Issue.7037
, pp. 1138-1143
-
-
Lawrence, T.1
Bebien, M.2
Liu, G.Y.3
Nizet, V.4
Karin, M.5
-
16
-
-
45149087674
-
An antiinflammatory role for IKKβ through the inhibition of "classical" macrophage activation
-
Fong CH, et al. An antiinflammatory role for IKKβ through the inhibition of "classical" macrophage activation. J Exp Med. 2008;205(6):1269-1276.
-
(2008)
J Exp Med.
, vol.205
, Issue.6
, pp. 1269-1276
-
-
Fong, C.H.1
-
17
-
-
34248570795
-
Ubiquitin-mediated activation of TAK1 and IKK
-
Adhikari A, Xu M, Chen ZJ. Ubiquitin-mediated activation of TAK1 and IKK. Oncogene. 2007;26(22):3214-3226.
-
(2007)
Oncogene.
, vol.26
, Issue.22
, pp. 3214-3226
-
-
Adhikari, A.1
Xu, M.2
Chen, Z.J.3
-
18
-
-
0033669743
-
TAK1 regulates multiple protein kinase cascades activated by bacterial lipopolysaccharide
-
Lee J, Mira-Arbibe L, Ulevitch RJ. TAK1 regulates multiple protein kinase cascades activated by bacterial lipopolysaccharide. J Leukoc Biol. 2000;68(6):909-915.
-
(2000)
J Leukoc Biol.
, vol.68
, Issue.6
, pp. 909-915
-
-
Lee, J.1
Mira-Arbibe, L.2
Ulevitch, R.J.3
-
19
-
-
15444366928
-
A novel NF-κB pathway involving IKKβ and p65/RelA Ser-536 phosphorylation results in p53 Inhibition in the absence of NF-κB transcriptional activity
-
Jeong SJ, Pise-Masison CA, Radonovich MF, Park HU, Brady JN. A novel NF-κB pathway involving IKKβ and p65/RelA Ser-536 phosphorylation results in p53 Inhibition in the absence of NF-κB transcriptional activity. J Biol Chem. 2005;280(11):10326-10332.
-
(2005)
J Biol Chem.
, vol.280
, Issue.11
, pp. 10326-10332
-
-
Jeong, S.J.1
Pise-Masison, C.A.2
Radonovich, M.F.3
Park, H.U.4
Brady, J.N.5
-
20
-
-
0032589462
-
IκB kinases phosphorylate NF-κB p65 subunit on serine 536 in the transactivation domain
-
Sakurai H, Chiba H, Miyoshi H, Sugita T, Toriumi W. IκB kinases phosphorylate NF-κB p65 subunit on serine 536 in the transactivation domain. J Biol Chem. 1999;274(43):30353-30356.
-
(1999)
J Biol Chem.
, vol.274
, Issue.43
, pp. 30353-30356
-
-
Sakurai, H.1
Chiba, H.2
Miyoshi, H.3
Sugita, T.4
Toriumi, W.5
-
21
-
-
84964636180
-
Disabled-2: A modular scaffold protein with multifaceted functions in signaling
-
Finkielstein CV, Capelluto DGS. Disabled-2: A modular scaffold protein with multifaceted functions in signaling. Inside the Cell. 2016;1(1):48-58.
-
(2016)
Inside the Cell.
, vol.1
, Issue.1
, pp. 48-58
-
-
Finkielstein, C.V.1
Capelluto, D.G.S.2
-
22
-
-
0029019969
-
Cloning of a novel phosphoprotein regulated by colonystimulating factor 1 shares a domain with the Drosophila disabled gene product
-
Xu XX, Yang W, Jackowski S, Rock CO. Cloning of a novel phosphoprotein regulated by colonystimulating factor 1 shares a domain with the Drosophila disabled gene product. J Biol Chem. 1995;270(23):14184-14191.
-
(1995)
J Biol Chem.
, vol.270
, Issue.23
, pp. 14184-14191
-
-
Xu, X.X.1
Yang, W.2
Jackowski, S.3
Rock, C.O.4
-
23
-
-
0141480901
-
Crystal structures of the Dab homology domains of mouse disabled 1 and 2
-
Yun M, et al. Crystal structures of the Dab homology domains of mouse disabled 1 and 2. J Biol Chem. 2003;278(38):36572-36581.
-
(2003)
J Biol Chem.
, vol.278
, Issue.38
, pp. 36572-36581
-
-
Yun, M.1
-
24
-
-
0029968488
-
Sequence, genomic structure, and chromosomal assignment of human DOC-2
-
Albertsen HM, et al. Sequence, genomic structure, and chromosomal assignment of human DOC-2. Genomics. 1996;33(2):207-213.
-
(1996)
Genomics.
, vol.33
, Issue.2
, pp. 207-213
-
-
Albertsen, H.M.1
-
25
-
-
0037007229
-
Dual roles for the Dab2 adaptor protein in embryonic development and kidney transport
-
Morris SM. Dual roles for the Dab2 adaptor protein in embryonic development and kidney transport. EMBO J. 2002;21(7):1555-1564.
-
(2002)
EMBO J.
, vol.21
, Issue.7
, pp. 1555-1564
-
-
Morris, S.M.1
-
26
-
-
33749487743
-
The adaptor protein Dab2 sorts LDL receptors into coated pits independently of AP-2 and ARH
-
Maurer ME, Cooper JA. The adaptor protein Dab2 sorts LDL receptors into coated pits independently of AP-2 and ARH. J Cell Sci. 2006;119(20):4235-4246.
-
(2006)
J Cell Sci.
, vol.119
, Issue.20
, pp. 4235-4246
-
-
Maurer, M.E.1
Cooper, J.A.2
-
27
-
-
0034193309
-
Cytosolic adaptor protein Dab2 is an intracellular ligand of endocytic receptor gp600/megalin
-
Oleinikov AV, Zhao J, Makker SP. Cytosolic adaptor protein Dab2 is an intracellular ligand of endocytic receptor gp600/megalin. Biochem J. 2000;347(3):613.
-
(2000)
Biochem J.
, vol.347
, Issue.3
, pp. 613
-
-
Oleinikov, A.V.1
Zhao, J.2
Makker, S.P.3
-
28
-
-
78649672499
-
Type II transforming growth factor-beta receptor recycling is dependent upon the clathrin adaptor protein Dab2
-
Penheiter SG, et al. Type II transforming growth factor-beta receptor recycling is dependent upon the clathrin adaptor protein Dab2. Mol Biol Cell. 2010;21(22):4009-4019.
-
(2010)
Mol Biol Cell.
, vol.21
, Issue.22
, pp. 4009-4019
-
-
Penheiter, S.G.1
-
29
-
-
84874622432
-
Spatial regulation of VEGF receptor endocytosis in angiogenesis
-
Nakayama M, et al. Spatial regulation of VEGF receptor endocytosis in angiogenesis. Nat Cell Biol. 2013;15(3):249-260.
-
(2013)
Nat Cell Biol.
, vol.15
, Issue.3
, pp. 249-260
-
-
Nakayama, M.1
-
30
-
-
84869853098
-
Tissue-specific control of CFTR endocytosis by Dab2
-
Madden DR, Swiatecka-Urban A. Tissue-specific control of CFTR endocytosis by Dab2. Commun Integr Biol. 2012;5(5):473-476.
-
(2012)
Commun Integr Biol.
, vol.5
, Issue.5
, pp. 473-476
-
-
Madden, D.R.1
Swiatecka-Urban, A.2
-
31
-
-
84555189167
-
Dab2 is a key regulator of endocytosis and post-endocytic trafficking of the cystic fibrosis transmembrane conductance regulator
-
Fu L, Rab A, Tang L, Rowe S, Bebok Z, Collawn J. Dab2 is a key regulator of endocytosis and post-endocytic trafficking of the cystic fibrosis transmembrane conductance regulator. Biochem J. 2011;441(2):633-643.
-
(2011)
Biochem J.
, vol.441
, Issue.2
, pp. 633-643
-
-
Fu, L.1
Rab, A.2
Tang, L.3
Rowe, S.4
Bebok, Z.5
Collawn, J.6
-
32
-
-
0035099375
-
Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2
-
Morris SM, Cooper JA. Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2. Traffic. 2001;2(2):111-123.
-
(2001)
Traffic.
, vol.2
, Issue.2
, pp. 111-123
-
-
Morris, S.M.1
Cooper, J.A.2
-
33
-
-
0038275800
-
Regulation of the Wnt signaling pathway by disabled-2 (Dab2)
-
Hocevar BA. Regulation of the Wnt signaling pathway by disabled-2 (Dab2). EMBO J. 2003;22(12):3084-3094.
-
(2003)
EMBO J.
, vol.22
, Issue.12
, pp. 3084-3094
-
-
Hocevar, B.A.1
-
34
-
-
70449709580
-
Cutting edge: Dab2 is a FOXP3 target gene required for regulatory T cell function
-
Jain N, et al. Cutting edge: Dab2 is a FOXP3 target gene required for regulatory T cell function. J Immunol. 2009;183(7):4192-4196.
-
(2009)
J Immunol.
, vol.183
, Issue.7
, pp. 4192-4196
-
-
Jain, N.1
-
35
-
-
34547678149
-
Decreased DOC-2/DAB2 expression in urothelial carcinoma of the bladder
-
Karam JA, et al. Decreased DOC-2/DAB2 expression in urothelial carcinoma of the bladder. Clin Cancer Res. 2007;13(15):4400-4406.
-
(2007)
Clin Cancer Res.
, vol.13
, Issue.15
, pp. 4400-4406
-
-
Karam, J.A.1
-
36
-
-
34547757365
-
Frequent loss of Dab2 protein and infrequent promoter hypermethylation in breast cancer
-
Bagadi SAR, Prasad CP, Srivastava A, Prashad R, Gupta SD, Ralhan R. Frequent loss of Dab2 protein and infrequent promoter hypermethylation in breast cancer. Breast Cancer Res Treat. 2006;104(3):277-286.
-
(2006)
Breast Cancer Res Treat.
, vol.104
, Issue.3
, pp. 277-286
-
-
Bagadi, S.A.R.1
Prasad, C.P.2
Srivastava, A.3
Prashad, R.4
Gupta, S.D.5
Ralhan, R.6
-
37
-
-
0034671110
-
Structure, sequence, and promoter analysis of human disabled-2 gene (DAB2)
-
Sheng Z, et al. Structure, sequence, and promoter analysis of human disabled-2 gene (DAB2). Genomics. 2000;70(3):381-386.
-
(2000)
Genomics.
, vol.70
, Issue.3
, pp. 381-386
-
-
Sheng, Z.1
-
38
-
-
77955295090
-
Epigenetic downregulation of human disabled homolog 2 switches TGF-β from a tumor suppressor to a tumor promoter
-
Hannigan A, et al. Epigenetic downregulation of human disabled homolog 2 switches TGF-β from a tumor suppressor to a tumor promoter. J Clin Invest. 2010;120(8):2842-2857.
-
(2010)
J Clin Invest.
, vol.120
, Issue.8
, pp. 2842-2857
-
-
Hannigan, A.1
-
39
-
-
77956395148
-
Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma
-
Tong JH, et al. Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma. BMC Cancer. 2010;10(1):253.
-
(2010)
BMC Cancer.
, vol.10
, Issue.1
, pp. 253
-
-
Tong, J.H.1
-
40
-
-
0036470472
-
Disabled-2 is transcriptionally regulated by ICSBP and augments macrophage spreading and adhesion
-
Rosenbauer F, et al. Disabled-2 is transcriptionally regulated by ICSBP and augments macrophage spreading and adhesion. EMBO J. 2002;21(3):211-220.
-
(2002)
EMBO J.
, vol.21
, Issue.3
, pp. 211-220
-
-
Rosenbauer, F.1
-
41
-
-
85005765066
-
Endogenously regulated Dab2 worsens inflammatory injury in experimental autoimmune encephalomyelitis
-
Jokubaitis VG, et al. Endogenously regulated Dab2 worsens inflammatory injury in experimental autoimmune encephalomyelitis. Acta Neuropathol Commun. 2013;1(1):32.
-
(2013)
Acta Neuropathol Commun.
, vol.1
, Issue.1
, pp. 32
-
-
Jokubaitis, V.G.1
-
42
-
-
20444445870
-
Disabled-2 (Dab2) is required for transforming growth factor β-induced epithelial to mesenchymal transition (EMT)
-
Prunier C, Howe PH. Disabled-2 (Dab2) is required for transforming growth factor β-induced epithelial to mesenchymal transition (EMT). J Biol Chem. 2005;280(17):17540-17548.
-
(2005)
J Biol Chem.
, vol.280
, Issue.17
, pp. 17540-17548
-
-
Prunier, C.1
Howe, P.H.2
-
43
-
-
37349108810
-
Single bolus injection of bilirubin improves the clinical outcome in a mouse model of endotoxemia
-
Kadl A, Pontiller J, Exner M, Leitinger N. Single bolus injection of bilirubin improves the clinical outcome in a mouse model of endotoxemia. Shock. 2007;28(5):582-588.
-
(2007)
Shock.
, vol.28
, Issue.5
, pp. 582-588
-
-
Kadl, A.1
Pontiller, J.2
Exner, M.3
Leitinger, N.4
-
44
-
-
84868671526
-
Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase
-
Talukdar S, et al. Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase. Nat Med. 2012;18(9):1407-1412.
-
(2012)
Nat Med.
, vol.18
, Issue.9
, pp. 1407-1412
-
-
Talukdar, S.1
-
45
-
-
31044456529
-
CCR2 modulates inflammatory and metabolic effects of high-fat feeding
-
Weisberg SP, et al. CCR2 modulates inflammatory and metabolic effects of high-fat feeding. J Clin Invest. 2006;116(1):115-124.
-
(2006)
J Clin Invest.
, vol.116
, Issue.1
, pp. 115-124
-
-
Weisberg, S.P.1
-
46
-
-
42249085066
-
NUMBL interacts with TAB2 and inhibits TNFα and IL-1β-induced NF-κB activation
-
Ma Q, Zhou L, Shi H, Huo K. NUMBL interacts with TAB2 and inhibits TNFα and IL-1β-induced NF-κB activation. Cell Signal. 2008;20(6):1044-1051.
-
(2008)
Cell Signal.
, vol.20
, Issue.6
, pp. 1044-1051
-
-
Ma, Q.1
Zhou, L.2
Shi, H.3
Huo, K.4
-
47
-
-
76349083124
-
NUMBL interacts with TRAF6 and promotes the degradation of TRAF6
-
Zhou L, Ma Q, Shi H, Huo K. NUMBL interacts with TRAF6 and promotes the degradation of TRAF6. Biochem Biophys Res Commun. 2010;392(3):409-414.
-
(2010)
Biochem Biophys Res Commun.
, vol.392
, Issue.3
, pp. 409-414
-
-
Zhou, L.1
Ma, Q.2
Shi, H.3
Huo, K.4
-
48
-
-
0034672256
-
P67 isoform of mouse disabled 2 protein acts as a transcriptional activator during the differentiation of F9 cells
-
Cho SY, Jeon JW, Lee SH, Park SS. p67 isoform of mouse disabled 2 protein acts as a transcriptional activator during the differentiation of F9 cells. Biochem J. 2000;352(3):645.
-
(2000)
Biochem J.
, vol.352
, Issue.3
, pp. 645
-
-
Cho, S.Y.1
Jeon, J.W.2
Lee, S.H.3
Park, S.S.4
-
49
-
-
77649178841
-
The TAK1-TRAF6 signalling pathway
-
Landström M. The TAK1-TRAF6 signalling pathway. Int J Biochem Cell Biol. 2010;42(5):585-589.
-
(2010)
Int J Biochem Cell Biol.
, vol.42
, Issue.5
, pp. 585-589
-
-
Landström, M.1
|