메뉴 건너뛰기




Volumn 12, Issue 2, 2016, Pages 432-438

AMPK-dependent phosphorylation of lipid droplet protein PLIN2 triggers its degradation by CMA

Author keywords

Chaperones; Lipid droplets; Lysosome associated membrane protein 2A; Lysosomes; Perilipins; Protein degradation

Indexed keywords

ADENYLATE KINASE; FAT DROPLET; PERILIPIN; PERILIPIN 2; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; ADIPOPHILIN; CHAPERONE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PROTEIN KINASE INHIBITOR;

EID: 84964495084     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.1080/15548627.2015.1124226     Document Type: Article
Times cited : (177)

References (21)
  • 1
    • 0025294506 scopus 로고
    • Peptide sequences that target cytosolic proteins for lysosomal proteolysis
    • PMID:2204156
    • Dice JF. Peptide sequences that target cytosolic proteins for lysosomal proteolysis. Trends Biochem Sci 1990; 15:305-9 ; PMID:2204156; http://dx.doi.org/10.1016/0968-0004(90)90019-8
    • (1990) Trends Biochem Sci , vol.15 , pp. 305-309
    • Dice, J.F.1
  • 2
    • 84864318195 scopus 로고    scopus 로고
    • Chaperone-mediated autophagy: A unique way to enter the lysosome world
    • PMID:22748206
    • Kaushik S, Cuervo AM. Chaperone-mediated autophagy: a unique way to enter the lysosome world. Trends Cell Biol 2012; 22:407-17 ; PMID:22748206; http://dx.doi.org/10.1016/j.tcb.2012.05.006
    • (2012) Trends Cell Biol , vol.22 , pp. 407-417
    • Kaushik, S.1    Cuervo, A.M.2
  • 3
    • 0024975155 scopus 로고
    • A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins
    • PMID:2799391
    • Chiang H, Terlecky S, Plant C, Dice JF. A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins. Science 1989; 246:382-5 ; PMID:2799391; http://dx.doi.org/10.1126/science.2799391
    • (1989) Science , vol.246 , pp. 382-385
    • Chiang, H.1    Terlecky, S.2    Plant, C.3    Dice, J.F.4
  • 4
    • 0029837453 scopus 로고    scopus 로고
    • A receptor for the selective uptake and degradation of proteins by lysosomes
    • PMID:8662539
    • Cuervo AM, Dice JF. A receptor for the selective uptake and degradation of proteins by lysosomes. Science 1996; 273:501-3 ; PMID:8662539; http://dx.doi.org/10.1126/science.273.5274.501
    • (1996) Science , vol.273 , pp. 501-503
    • Cuervo, A.M.1    Dice, J.F.2
  • 5
    • 51349130544 scopus 로고    scopus 로고
    • The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane
    • PMID:18644871
    • Bandyopadhyay U, Kaushik S, Varticovski L, Cuervo AM. The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane. Mol Cell Biol 2008; 28:5747-63 ; PMID:18644871; http://dx.doi.org/10.1128/MCB.02070-07
    • (2008) Mol Cell Biol , vol.28 , pp. 5747-5763
    • Bandyopadhyay, U.1    Kaushik, S.2    Varticovski, L.3    Cuervo, A.M.4
  • 6
    • 0034282931 scopus 로고    scopus 로고
    • Import of a cytosolic protein into lysosomes by chaperone-mediated autophagy depends on its folding state
    • PMID:10862611
    • Salvador N, Aguado C, Horst M, Knecht E. Import of a cytosolic protein into lysosomes by chaperone-mediated autophagy depends on its folding state. Journal of Biological Chemistry 2000; 275:27447-56 ; PMID:10862611
    • (2000) Journal of Biological Chemistry , vol.275 , pp. 27447-27456
    • Salvador, N.1    Aguado, C.2    Horst, M.3    Knecht, E.4
  • 7
    • 0030923854 scopus 로고    scopus 로고
    • An intralysosomal hsp70 is required for a selective pathway of lysosomal protein degradation
    • PMID:9151685
    • Agarraberes F, Terlecky S, Dice J. An intralysosomal hsp70 is required for a selective pathway of lysosomal protein degradation. J Cell Biol 1997; 137:825-34 ; PMID:9151685; http://dx.doi.org/10.1083/jcb.137.4.825
    • (1997) J Cell Biol , vol.137 , pp. 825-834
    • Agarraberes, F.1    Terlecky, S.2    Dice, J.3
  • 8
    • 84930182353 scopus 로고    scopus 로고
    • Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis
    • PMID:25961502
    • Kaushik S, Cuervo AM. Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis. Nat Cell Biol 2015; 17:759-70 ; PMID:25961502; http://dx.doi.org/10.1038/ncb3166
    • (2015) Nat Cell Biol , vol.17 , pp. 759-770
    • Kaushik, S.1    Cuervo, A.M.2
  • 9
    • 79955631150 scopus 로고    scopus 로고
    • Autophagy in the cellular energetic balance
    • PMID:21531332
    • Singh R, Cuervo AM. Autophagy in the cellular energetic balance. Cell Metab 2011; 13:495-504 ; PMID:21531332; http://dx.doi.org/10.1016/j.cmet.2011.04.004
    • (2011) Cell Metab , vol.13 , pp. 495-504
    • Singh, R.1    Cuervo, A.M.2
  • 10
    • 84913592131 scopus 로고    scopus 로고
    • Deficient chaperone-mediated autophagy in liver leads to metabolic dysregulation
    • PMID:25043815
    • Schneider JL, Suh Y, Cuervo AM. Deficient chaperone-mediated autophagy in liver leads to metabolic dysregulation. CellMetab 2014; 20:417-32 ; PMID:25043815; http://dx.doi.org/10.1016/j.cmet.2014.06.009
    • (2014) Cellmetab , vol.20 , pp. 417-432
    • Schneider, J.L.1    Suh, Y.2    Cuervo, A.M.3
  • 11
    • 33745815985 scopus 로고    scopus 로고
    • AMP-activated protein kinase signaling in metabolic regulation
    • PMID:16823475
    • Long YC, Zierath JR. AMP-activated protein kinase signaling in metabolic regulation. J Clin Invest 2006; 116:1776-83 ; PMID:16823475; http://dx.doi.org/10.1172/JCI29044
    • (2006) J Clin Invest , vol.116 , pp. 1776-1783
    • Long, Y.C.1    Zierath, J.R.2
  • 13
    • 84938072487 scopus 로고    scopus 로고
    • Autophagy at the crossroads of catabolism and anabolism
    • PMID:26177004
    • Kaur J, Debnath J. Autophagy at the crossroads of catabolism and anabolism. Nat Rev Mol Cell Biol 2015; 16:461-72 ; PMID:26177004; http://dx.doi.org/10.1038/nrm4024
    • (2015) Nat Rev Mol Cell Biol , vol.16 , pp. 461-472
    • Kaur, J.1    Debnath, J.2
  • 15
    • 80053476420 scopus 로고    scopus 로고
    • The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR
    • PMID:21460621
    • Egan D, Kim J, Shaw RJ, Guan KL. The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR. Autophagy 2011; 7:643-4 ; PMID:21460621; http://dx.doi.org/10.4161/auto.7.6.15123
    • (2011) Autophagy , vol.7 , pp. 643-644
    • Egan, D.1    Kim, J.2    Shaw, R.J.3    Guan, K.L.4
  • 16
    • 84941602304 scopus 로고    scopus 로고
    • AMPK activation promotes lipid droplet dispersion on detyrosinated microtubules to increase mitochondrial fatty acid oxidation
    • PMID:26013497
    • Herms A, Bosch M, Reddy BJ, Schieber NL, Fajardo A, Ruperez C, Fernandez-Vidal A, Ferguson C, Rentero C, Tebar F, et al. AMPK activation promotes lipid droplet dispersion on detyrosinated microtubules to increase mitochondrial fatty acid oxidation. Nat Commun 2015; 6:7176 ; PMID:26013497; http://dx.doi.org/10.1038/ncomms8176
    • (2015) Nat Commun , vol.6 , pp. 7176
    • Herms, A.1    Bosch, M.2    Reddy, B.J.3    Schieber, N.L.4    Fajardo, A.5    Ruperez, C.6    Fernandez-Vidal, A.7    Ferguson, C.8    Rentero, C.9    Tebar, F.10
  • 18
    • 33645829816 scopus 로고    scopus 로고
    • Consequences of the selective blockage of chaperone-mediated autophagy
    • PMID:16585532
    • Massey AC, Kaushik S, Sovak G, Kiffin R, Cuervo AM. Consequences of the selective blockage of chaperone-mediated autophagy. Proc Nat Acad Sci USA 2006; 103:5905-10 ; PMID:16585532; http://dx.doi.org/10.1073/pnas.0507436103
    • (2006) Proc Nat Acad Sci USA , vol.103 , pp. 5905-5910
    • Massey, A.C.1    Kaushik, S.2    Sovak, G.3    Kiffin, R.4    Cuervo, A.M.5
  • 19
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide to nitrocellulose sheets: Procedure and some applications
    • PMID:388439
    • Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci 1979; 76:4350-4 ; PMID:388439; http://dx.doi.org/10.1073/pnas.76.9.4350
    • (1979) Proc Natl Acad Sci , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 20
    • 33845764296 scopus 로고    scopus 로고
    • A guided tour into subcellular colocalization analysis in light microscopy
    • PMID:17210054
    • Bolte S, Cordelieres FP. A guided tour into subcellular colocalization analysis in light microscopy. J Microsc 2006; 224:213-32 ; PMID:17210054; http://dx.doi.org/10.1111/j.1365-2818.2006.01706.x
    • (2006) J Microsc , vol.224 , pp. 213-232
    • Bolte, S.1    Cordelieres, F.P.2
  • 21
    • 71849104860 scopus 로고
    • Protein measurement with the Folin phenol reagent
    • PMID:14907713
    • Lowry O, Rosebrough N, Farr A, Randall R. Protein measurement with the Folin phenol reagent. J Biol Chem 1951; 193:265-75 ; PMID:14907713
    • (1951) J Biol Chem , vol.193 , pp. 265-275
    • Lowry, O.1    Rosebrough, N.2    Farr, A.3    Randall, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.