-
1
-
-
84862668222
-
The dynamic roles of intracellular lipid droplets: From archaea to mammals
-
Murphy D. J. The dynamic roles of intracellular lipid droplets: from archaea to mammals. Protoplasma 249, 541-585 (2012
-
(2012)
Protoplasma
, vol.249
, pp. 541-585
-
-
Murphy, D.J.1
-
2
-
-
84895735915
-
Review biogenesis of the multifunctional lipid droplet: Lipids, proteins, and sites
-
Pol A., Gross S. P., & Parton R. G. Review: biogenesis of the multifunctional lipid droplet: lipids, proteins, and sites. J. Cell Biol. 204, 635-646 (2014
-
(2014)
J. Cell Biol
, vol.204
, pp. 635-646
-
-
Pol, A.1
Gross, S.P.2
Parton, R.G.3
-
3
-
-
84858020291
-
Fat signals-lipases and lipolysis in lipid metabolism and signaling
-
Zechner R., et al. FAT SIGNALS-lipases and lipolysis in lipid metabolism and signaling. Cell Metab. 15, 279-291 (2012
-
(2012)
Cell Metab
, vol.15
, pp. 279-291
-
-
Zechner, R.1
-
4
-
-
84880036446
-
Balancing the fat: Lipid droplets and human disease
-
Krahmer N., Farese, Jr. R. V., & Walther T. C. Balancing the fat: lipid droplets and human disease. EMBO Mol. Med. 5, 905-915 (2013
-
(2013)
Embo Mol. Med
, vol.5
, pp. 905-915
-
-
Krahmer, N.1
Farese, R.V.2
Walther, T.C.3
-
6
-
-
84861913952
-
Lipid droplets and cellular lipid metabolism
-
Walther T. C., & Farese, Jr. R. V. Lipid droplets and cellular lipid metabolism. Annu. Rev. Biochem. 81, 687-714 (2012
-
(2012)
Annu. Rev. Biochem
, vol.81
, pp. 687-714
-
-
Walther, T.C.1
Farese, R.V.2
-
7
-
-
8944256087
-
Acylglycerol recycling from triacylglycerol to phospholipid, not lipase activity, is defective in neutral lipid storage disease fibroblasts
-
Igal R. A., & Coleman R. A. Acylglycerol recycling from triacylglycerol to phospholipid, not lipase activity, is defective in neutral lipid storage disease fibroblasts. J. Biol. Chem. 271, 16644-16651 (1996
-
(1996)
J. Biol. Chem
, vol.271
, pp. 16644-16651
-
-
Igal, R.A.1
Coleman, R.A.2
-
8
-
-
45149123679
-
Hepatic overexpression of hormone-sensitive lipase and adipose triglyceride lipase promotes fatty acid oxidation, stimulates direct release of free fatty acids, and ameliorates steatosis
-
Reid B. N., et al. Hepatic overexpression of hormone-sensitive lipase and adipose triglyceride lipase promotes fatty acid oxidation, stimulates direct release of free fatty acids, and ameliorates steatosis. J. Biol. Chem. 283, 13087-13099 (2008
-
(2008)
J. Biol. Chem
, vol.283
, pp. 13087-13099
-
-
Reid, B.N.1
-
9
-
-
77954890412
-
Adipose differentiation-related protein regulates lipids and insulin in pancreatic islets
-
Faleck D. M., et al. Adipose differentiation-related protein regulates lipids and insulin in pancreatic islets. Am. J. Physiol. Endocrinol. Metab. 299, E249-E257 (2010
-
(2010)
Am. J. Physiol. Endocrinol. Metab
, vol.299
, pp. E249-E257
-
-
Faleck, D.M.1
-
10
-
-
70350169763
-
Fat on the move: Intracellular motion of lipid droplets
-
Welte M. A. Fat on the move: intracellular motion of lipid droplets. Biochem. Soc. Trans. 37, 991-996 (2009
-
(2009)
Biochem. Soc. Trans
, vol.37
, pp. 991-996
-
-
Welte, M.A.1
-
11
-
-
0346099345
-
Dynamic and regulated association of caveolin with lipid bodies: Modulation of lipid body motility and function by a dominant negative mutant
-
Pol A., et al. Dynamic and regulated association of caveolin with lipid bodies: modulation of lipid body motility and function by a dominant negative mutant. Mol. Biol. Cell 15, 99-110 (2004
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 99-110
-
-
Pol, A.1
-
12
-
-
22744434906
-
Regulation of lipid-droplet transport by the perilipin homolog LSD2
-
Welte M. A., et al. Regulation of lipid-droplet transport by the perilipin homolog LSD2. Curr. Biol. 15, 1266-1275 (2005
-
(2005)
Curr. Biol
, vol.15
, pp. 1266-1275
-
-
Welte, M.A.1
-
13
-
-
84868522484
-
Yeast and cancer cells -common principles in lipid metabolism
-
Natter K., & Kohlwein S. D. Yeast and cancer cells -common principles in lipid metabolism. Biochim. Biophys. Acta 1831, 314-326 (2013
-
(2013)
Biochim. Biophys. Acta
, vol.1831
, pp. 314-326
-
-
Natter, K.1
Kohlwein, S.D.2
-
14
-
-
80054046029
-
Aerobic glycolysis: Meeting the metabolic requirements of cell proliferation
-
Lunt S. Y., & Vander Heiden M. G. Aerobic glycolysis: meeting the metabolic requirements of cell proliferation. Annu. Rev. Cell Dev. Biol. 27, 441-464 (2011
-
(2011)
Annu. Rev. Cell Dev. Biol
, vol.27
, pp. 441-464
-
-
Lunt, S.Y.1
Vander Heiden, M.G.2
-
15
-
-
20844449238
-
Amp-activated protein kinase induces a p53-dependent metabolic checkpoint
-
Jones R. G., et al. AMP-activated protein kinase induces a p53-dependent metabolic checkpoint. Mol. Cell 18, 283-293 (2005
-
(2005)
Mol. Cell
, vol.18
, pp. 283-293
-
-
Jones, R.G.1
-
16
-
-
84881317164
-
Cell-to-cell heterogeneity in lipid droplets suggests a mechanism to reduce lipotoxicity
-
Herms A., et al. Cell-to-cell heterogeneity in lipid droplets suggests a mechanism to reduce lipotoxicity. Curr. Biol. 23, 1489-1496 (2013
-
(2013)
Curr. Biol
, vol.23
, pp. 1489-1496
-
-
Herms, A.1
-
17
-
-
84884806397
-
Cell survival during complete nutrient deprivation depends on lipid droplet-fueled beta-oxidation of fatty acids
-
Cabodevilla A. G., et al. Cell survival during complete nutrient deprivation depends on lipid droplet-fueled beta-oxidation of fatty acids. J. Biol. Chem. 288, 27777-27788 (2013
-
(2013)
J. Biol. Chem
, vol.288
, pp. 27777-27788
-
-
Cabodevilla, A.G.1
-
18
-
-
37449020075
-
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance
-
Koves T. R., et al. Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance. Cell Metab. 7, 45-56 (2008
-
(2008)
Cell Metab
, vol.7
, pp. 45-56
-
-
Koves, T.R.1
-
19
-
-
0034623950
-
Perilipin A increases triacylglycerol storage by decreasing the rate of triacylglycerol hydrolysis
-
Brasaemle D. L., et al. Perilipin A increases triacylglycerol storage by decreasing the rate of triacylglycerol hydrolysis. J. Biol. Chem. 275, 38486-38493 (2000
-
(2000)
J. Biol. Chem
, vol.275
, pp. 38486-38493
-
-
Brasaemle, D.L.1
-
20
-
-
79955623510
-
During autophagy mitochondria elongate, are spared from degradation and sustain cell viability
-
Gomes L. C., Di Benedetto G., & Scorrano L. During autophagy mitochondria elongate, are spared from degradation and sustain cell viability. Nat. Cell Biol. 13, 589-598 (2011
-
(2011)
Nat. Cell Biol
, vol.13
, pp. 589-598
-
-
Gomes, L.C.1
Di Benedetto, G.2
Scorrano, L.3
-
21
-
-
33744904687
-
The phosphorylation of serine 492 of perilipin a directs lipid droplet fragmentation and dispersion
-
Marcinkiewicz A., Gauthier D., Garcia A., & Brasaemle D. L. The phosphorylation of serine 492 of perilipin a directs lipid droplet fragmentation and dispersion. J. Biol. Chem. 281, 11901-11909 (2006
-
(2006)
J. Biol. Chem
, vol.281
, pp. 11901-11909
-
-
Marcinkiewicz, A.1
Gauthier, D.2
Garcia, A.3
Brasaemle, D.L.4
-
22
-
-
77955459468
-
ER sliding dynamics and ER-mitochondrial contacts occur on acetylated microtubules
-
Friedman J. R., Webster B. M., Mastronarde D. N., Verhey K. J., & Voeltz G. K. ER sliding dynamics and ER-mitochondrial contacts occur on acetylated microtubules. J. Cell Biol. 190, 363-375 (2010
-
(2010)
J. Cell Biol
, vol.190
, pp. 363-375
-
-
Friedman, J.R.1
Webster, B.M.2
Mastronarde, D.N.3
Verhey, K.J.4
Voeltz, G.K.5
-
23
-
-
77954935925
-
Starvation-induced hyperacetylation of tubulin is required for the stimulation of autophagy by nutrient deprivation
-
Geeraert C., et al. Starvation-induced hyperacetylation of tubulin is required for the stimulation of autophagy by nutrient deprivation. J. Biol. Chem. 285, 24184-24194 (2010
-
(2010)
J. Biol. Chem
, vol.285
, pp. 24184-24194
-
-
Geeraert, C.1
-
24
-
-
77957868249
-
Post-translational modifications of microtubules
-
Wloga D., & Gaertig J. Post-translational modifications of microtubules. J. Cell Sci. 123, 3447-3455 (2010
-
(2010)
J. Cell Sci
, vol.123
, pp. 3447-3455
-
-
Wloga, D.1
Gaertig, J.2
-
25
-
-
0023582253
-
Control of microtubule nucleation and stability in madin-darby canine kidney cells: The occurrence of noncentrosomal, stable detyrosinated microtubules
-
Bre M. H., Kreis T. E., & Karsenti E. Control of microtubule nucleation and stability in Madin-Darby canine kidney cells: the occurrence of noncentrosomal, stable detyrosinated microtubules. J. Cell Biol. 105, 1283-1296 (1987
-
(1987)
J. Cell Biol
, vol.105
, pp. 1283-1296
-
-
Bre, M.H.1
Kreis, T.E.2
Karsenti, E.3
-
26
-
-
84895764551
-
Acyl-CoA synthetase 3 promotes lipid droplet biogenesis in ER microdomains
-
Kassan A., et al. Acyl-CoA synthetase 3 promotes lipid droplet biogenesis in ER microdomains. J. Cell Biol. 203, 985-1001 (2013
-
(2013)
J. Cell Biol
, vol.203
, pp. 985-1001
-
-
Kassan, A.1
-
27
-
-
27744533005
-
Kinesin-2 is a motor for late endosomes and lysosomes
-
Brown C. L., et al. Kinesin-2 is a motor for late endosomes and lysosomes. Traffic 6, 1114-1124 (2005
-
(2005)
Traffic
, vol.6
, pp. 1114-1124
-
-
Brown, C.L.1
-
28
-
-
84858782079
-
Ampk a nutrient and energy sensor that maintains energy homeostasis
-
Hardie D. G., Ross F. A., & Hawley S. A. AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nat. Rev. Mol. Cell Biol. 13, 251-262 (2012
-
(2012)
Nat. Rev. Mol. Cell Biol
, vol.13
, pp. 251-262
-
-
Hardie, D.G.1
Ross, F.A.2
Hawley, S.A.3
-
29
-
-
33745183847
-
Functions of AMP-activated protein kinase in adipose tissue
-
Daval M., Foufelle F., & Ferre P. Functions of AMP-activated protein kinase in adipose tissue. J. Physiol. 574, 55-62 (2006
-
(2006)
J. Physiol
, vol.574
, pp. 55-62
-
-
Daval, M.1
Foufelle, F.2
Ferre, P.3
-
30
-
-
85047689953
-
5-aminoimidazole-4-carboxamide ribonucleoside a specific method for activating amp-activated protein kinase in intact cells?
-
Corton J. M., Gillespie J. G., Hawley S. A., & Hardie D. G. 5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells?. Eur. J. Biochem. 229, 558-565 (1995
-
(1995)
Eur. J. Biochem
, vol.229
, pp. 558-565
-
-
Corton, J.M.1
Gillespie, J.G.2
Hawley, S.A.3
Hardie, D.G.4
-
31
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
Zhou G., et al. Role of AMP-activated protein kinase in mechanism of metformin action. J. Clin. Invest. 108, 1167-1174 (2001
-
(2001)
J. Clin. Invest
, vol.108
, pp. 1167-1174
-
-
Zhou, G.1
-
32
-
-
36549040859
-
The selectivity of protein kinase inhibitors: A further update
-
Bain J., et al. The selectivity of protein kinase inhibitors: a further update. Biochem. J. 408, 297-315 (2007
-
(2007)
Biochem. J.
, vol.408
, pp. 297-315
-
-
Bain, J.1
-
33
-
-
33745840203
-
5′-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments
-
Laderoute K. R., et al. 5′-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments. Mol. Cell Biol. 26, 5336-5347 (2006
-
(2006)
Mol. Cell Biol
, vol.26
, pp. 5336-5347
-
-
Laderoute, K.R.1
-
34
-
-
79251587803
-
Phosphorylation of ulk1 (hatg1) by amp-activated protein kinase connects energy sensing to mitophagy
-
Egan D. F., et al. Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy. Science 331, 456-461 (2011
-
(2011)
Science
, vol.331
, pp. 456-461
-
-
Egan, D.F.1
-
35
-
-
65949095803
-
Autophagy regulates lipid metabolism
-
Singh R., et al. Autophagy regulates lipid metabolism. Nature 458, 1131-1135 (2009
-
(2009)
Nature
, vol.458
, pp. 1131-1135
-
-
Singh, R.1
-
36
-
-
84889887123
-
Single phosphorylation sites in acc1 and acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin
-
Fullerton M. D., et al. Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin. Nat. Med. 19, 1649-1654 (2013
-
(2013)
Nat. Med
, vol.19
, pp. 1649-1654
-
-
Fullerton, M.D.1
-
37
-
-
33751579134
-
Acetyl-coenzyme A carboxylases: Versatile targets for drug discovery
-
Tong L., & Harwood, Jr. H. J. Acetyl-coenzyme A carboxylases: versatile targets for drug discovery. J. Cell. Biochem. 99, 1476-1488 (2006
-
(2006)
J. Cell. Biochem
, vol.99
, pp. 1476-1488
-
-
Tong, L.1
Harwood, H.J.2
-
38
-
-
77953121697
-
Ampk controls the speed of microtubule polymerization and directional cell migration through clip-170 phosphorylation
-
Nakano A., et al. AMPK controls the speed of microtubule polymerization and directional cell migration through CLIP-170 phosphorylation. Nat. Cell Biol. 12, 583-590 (2010
-
(2010)
Nat. Cell Biol
, vol.12
, pp. 583-590
-
-
Nakano, A.1
-
39
-
-
84890243481
-
The association of microtubules with tight junctions is promoted by cingulin phosphorylation by ampk
-
Yano T., Matsui T., Tamura A., Uji M., & Tsukita S. The association of microtubules with tight junctions is promoted by cingulin phosphorylation by AMPK. J. Cell Biol. 203, 605-614 (2013
-
(2013)
J. Cell Biol
, vol.203
, pp. 605-614
-
-
Yano, T.1
Matsui, T.2
Tamura, A.3
Uji, M.4
Tsukita, S.5
-
40
-
-
33847755111
-
Influence of endurance exercise training and sex on intramyocellular lipid and mitochondrial ultrastructure, substrate use, and mitochondrial enzyme activity
-
Tarnopolsky M. A., et al. Influence of endurance exercise training and sex on intramyocellular lipid and mitochondrial ultrastructure, substrate use, and mitochondrial enzyme activity. Am. J. Physiol. Regul. Integr. Comp. Physiol. 292, R1271-R1278 (2007
-
(2007)
Am. J. Physiol. Regul. Integr. Comp. Physiol
, vol.292
, pp. R1271-R1278
-
-
Tarnopolsky, M.A.1
-
41
-
-
84904305374
-
Mitochondrial and cellular mechanisms for managing lipid excess
-
Aon M. A., Bhatt N., & Cortassa S. C. Mitochondrial and cellular mechanisms for managing lipid excess. Front. Physiol. 5, 282 (2014
-
(2014)
Front. Physiol
, vol.5
, pp. 282
-
-
Aon, M.A.1
Bhatt, N.2
Cortassa, S.C.3
-
42
-
-
80455135722
-
Perilipin 5, a lipid droplet-associated protein, provides physical and metabolic linkage to mitochondria
-
Wang H., et al. Perilipin 5, a lipid droplet-associated protein, provides physical and metabolic linkage to mitochondria. J. Lipid Res. 52, 2159-2168 (2011
-
(2011)
J. Lipid Res
, vol.52
, pp. 2159-2168
-
-
Wang, H.1
-
43
-
-
69249218992
-
Lipid droplets interact with mitochondria using SNAP23
-
Jagerstrom S., et al. Lipid droplets interact with mitochondria using SNAP23. Cell Biol. Int. 33, 934-940 (2009
-
(2009)
Cell Biol. Int
, vol.33
, pp. 934-940
-
-
Jagerstrom, S.1
-
44
-
-
77957827008
-
Intracellular transport: ER and mitochondria meet and greet along designated tracks
-
Barlan K., & Gelfand V. I. Intracellular transport: ER and mitochondria meet and greet along designated tracks. Curr. Biol. 20, R845-R847 (2010
-
(2010)
Curr. Biol
, vol.20
, pp. R845-R847
-
-
Barlan, K.1
Gelfand, V.I.2
-
45
-
-
57149145788
-
Consequences of motor copy number on the intracellular transport of kinesin-1-driven lipid droplets
-
Shubeita G. T., et al. Consequences of motor copy number on the intracellular transport of kinesin-1-driven lipid droplets. Cell 135, 1098-1107 (2008
-
(2008)
Cell
, vol.135
, pp. 1098-1107
-
-
Shubeita, G.T.1
-
46
-
-
84874485595
-
In vivo optical trapping indicates kinesin's stall force is reduced by dynein during intracellular transport
-
Blehm B. H., Schroer T. A., Trybus K. M., Chemla Y. R., & Selvin P. R. In vivo optical trapping indicates kinesin's stall force is reduced by dynein during intracellular transport. Proc. Natl Acad. Sci. USA 110, 3381-3386 (2013
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 3381-3386
-
-
Blehm, B.H.1
Schroer, T.A.2
Trybus, K.M.3
Chemla, Y.R.4
Selvin, P.R.5
-
47
-
-
84871967163
-
Quantitative optical trapping on single organelles in cell extract
-
Barak P., Rai A., Rai P., & Mallik R. Quantitative optical trapping on single organelles in cell extract. Nat. Methods 10, 68-70 (2013
-
(2013)
Nat. Methods
, vol.10
, pp. 68-70
-
-
Barak, P.1
Rai, A.2
Rai, P.3
Mallik, R.4
-
48
-
-
43149106461
-
Differential trafficking of Kif5c on tyrosinated and detyrosinated microtubules in live cells
-
Dunn S., et al. Differential trafficking of Kif5c on tyrosinated and detyrosinated microtubules in live cells. J. Cell Sci. 121, 1085-1095 (2008
-
(2008)
J. Cell Sci
, vol.121
, pp. 1085-1095
-
-
Dunn, S.1
-
49
-
-
84902983688
-
Effects of alpha-tubulin K40 acetylation and detyrosination on kinesin-1 motility in a purified system
-
Kaul N., Soppina V., & Verhey K. J. Effects of alpha-tubulin K40 acetylation and detyrosination on kinesin-1 motility in a purified system. Biophys. J. 106, 2636-2643 (2014
-
(2014)
Biophys. J.
, vol.106
, pp. 2636-2643
-
-
Kaul, N.1
Soppina, V.2
Verhey, K.J.3
-
50
-
-
33845261493
-
A rapid method of total lipid extraction and purification
-
Bligh E. G., & Dyer W. J. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37, 911-917 (1959
-
(1959)
Can. J. Biochem. Physiol
, vol.37
, pp. 911-917
-
-
Bligh, E.G.1
Dyer, W.J.2
-
52
-
-
0035809933
-
A caveolin dominant negative mutant associates with lipid bodies and induces intracellular cholesterol imbalance
-
Pol A., et al. A caveolin dominant negative mutant associates with lipid bodies and induces intracellular cholesterol imbalance. J. Cell Biol. 152, 1057-1070 (2001
-
(2001)
J. Cell Biol
, vol.152
, pp. 1057-1070
-
-
Pol, A.1
-
53
-
-
0033034002
-
The early-sorting endocytic compartment of rat hepatocytes is involved in the intracellular pathway of caveolin-1 (vip-21
-
Pol A., Calvo M., Lu A., & Enrich C. The early-sorting endocytic compartment of rat hepatocytes is involved in the intracellular pathway of caveolin-1 (VIP-21). Hepatology 29, 1848-1857 (1999
-
(1999)
Hepatology
, vol.29
, pp. 1848-1857
-
-
Pol, A.1
Calvo, M.2
Lu, A.3
Enrich, C.4
|