One-Step Self-Assembling Method to Prepare Dual-Functional Transferrin Nanoparticles for Antitumor Drug Delivery

Journal of Pharmaceutical Sciences

Volumn 105, Issue 3, 2016, Pages 1269-1276

  Wang, Kaikai ^a,b   Yuan, Ahu ^a   Yu, Jiaqian ^a   Wu, Jinhui ^a,b   Hu, Yiqiao ^a  

^a NANJING UNIVERSITY   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

drug delivery systems; nanotechnology; protein folding refolding; proteins; self assembly; solubility; targeted drug delivery

Indexed keywords

MERCAPTOETHANOL; NANOCARRIER; PACLITAXEL; TRANSFERRIN; TRANSFERRIN NANOPARTICLE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; DRUG CARRIER; NANOPARTICLE; PACLITAXEL-TRANSFERRIN; TAXOID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CELL VIABILITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; DISULFIDE BOND; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG STABILITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HYDROPHOBICITY; IN VITRO STUDY; MOUSE; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PROTEIN SECONDARY STRUCTURE; PROTEIN TARGETING; RECEPTOR BINDING; RECEPTOR BINDING ASSAY; SUSTAINED DRUG RELEASE; TUMOR GROWTH; TUMOR XENOGRAFT; ANIMAL; CHEMISTRY; MCF-7 CELL LINE; PROCEDURES; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HUMANS; MCF-7 CELLS; MICE; NANOPARTICLES; PACLITAXEL; TAXOIDS; TRANSFERRIN;

EID: 84964413567     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1016/j.xphs.2015.12.007     Document Type: Article

References (38)

1. C. Oerlemans, W. Bult, M. Bos, G. Storm, J.F. Nijsen, and W.E. Hennink Polymeric micelles in anticancer therapy: targeting, imaging and triggered release Pharm Res 27 12 2010 2569 2589
2. S.C. Kim, D.W. Kim, Y.H. Shim, and et al. In vivo evaluation of polymeric micellar paclitaxel formulation: toxicity and efficacy J Control Release 72 1-3 2001 191 202
3. D.W. Kim, S.Y. Kim, H.K. Kim, and et al. Multicenter phase II trial of Genexol-PM, a novel Cremophor-free, polymeric micelle formulation of paclitaxel, with cisplatin in patients with advanced non-small-cell lung cancer Ann Oncol 18 12 2007 2009 2014
4. S. Parveen, R. Misra, and S.K. Sahoo Nanoparticles: a boon to drug delivery, therapeutics, diagnostics and imaging Nanomedicine 8 2 2012 147 166
5. I.R. Vlahov, and C.P. Leamon Engineering folate-drug conjugates to target cancer: from chemistry to clinic Bioconjugate Chem 23 7 2012 1357 1369
6. O.C. Farokhzad, and R. Langer Impact of Nanotechnology on drug delivery ACS Nano 3 1 2009 16 20
7. A.K. Gupta, M. Gupta, S.J. Yarwood, and A.S. Curtis Effect of cellular uptake of gelatin nanoparticles on adhesion, morphology and cytoskeleton organisation of human fibroblasts J Control Release 95 2 2004 197 207
8. X. Zhen, X. Wang, C. Xie, W. Wu, and X. Jiang Cellular uptake, antitumor response and tumor penetration of cisplatin-loaded milk protein nanoparticles Biomaterials 34 4 2013 1372 1382
9. S. Jain, R. Mathur, M. Das, N.K. Swarnakar, and A.K. Mishra Synthesis, pharmacoscintigraphic evaluation and antitumor efficacy of methotrexate-loaded, folate-conjugated, stealth albumin nanoparticles Nanomedicine (Lond) 6 10 2011 1733 1754
10. R. Xu, M. Fisher, and R.L. Juliano Targeted albumin-based nanoparticles for delivery of amphipathic drugs Bioconjugate Chem 22 5 2011 870 878
11. B. Elsadek, and F. Kratz Impact of albumin on drug delivery-new applications on the horizon J Control Release 157 1 2012 4 28
12. F. Kratz Albumin as a drug carrier: design of prodrugs, drug conjugates and nanoparticles J Control Release 132 3 2008 171 183
13. F. Kratz, and B. Elsadek Clinical impact of serum proteins on drug delivery J Control Release 161 2 2012 429 445
14. W.J. Gradishar, S. Tjulandin, N. Davidson, and et al. Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer J Clin Oncol 23 31 2005 7794 7803
15. Z. Wang, Y. Yu, W. Dai, and et al. A specific peptide ligand-modified lipid nanoparticle carrier for the inhibition of tumor metastasis growth Biomaterials 34 3 2013 756 764
16. C. Wong, T. Stylianopoulos, J. Cui, and et al. Multistage nanoparticle delivery system for deep penetration into tumor tissue Proc Natl Acad Sci U S A 108 6 2011 2426 2431
17. M. Kawamoto, T. Horibe, M. Kohno, and K. Kawakami A novel transferrin receptor-targeted hybrid peptide disintegrates cancer cell membrane to induce rapid killing of cancer cells BMC Cancer 11 2011 359
18. I. Nakase, B. Gallis, T. Takatani-Nakase, and et al. Transferrin receptor-dependent cytotoxicity of artemisinin-transferrin conjugates on prostate cancer cells and induction of apoptosis Cancer Lett 274 2 2009 290 298
19. Z.M. Qian, H. Li, H. Sun, and K. Ho Targeted drug delivery via the transferrin receptor-mediated endocytosis pathway Pharmacol Rev 54 4 2002 561 587
20. J. Yue, S. Liu, R. Wang, and et al. Transferrin-conjugated micelles: enhanced accumulation and antitumor effect for transferrin-receptor-overexpressing cancer models Mol Pharm 9 2012 1919 1931
21. M.E. Davis, J.E. Zuckerman, C.H. Choi, and et al. Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles Nature 464 7291 2010 1067 1070
22. S. Wagner, F. Rothweiler, M.G. Anhorn, and et al. Enhanced drug targeting by attachment of an anti alphav integrin antibody to doxorubicin loaded human serum albumin nanoparticles Biomaterials 31 8 2010 2388 2398
23. B. Wilson, T.V. Ambika, R.D. Patel, J.L. Jenita, and S.R. Priyadarshini Nanoparticles based on albumin: preparation, characterization and the use for 5-flurouracil delivery Int J Biol Macromol 51 2012 874 878
24. S. Bae, K. Ma, T.H. Kim, and et al. Doxorubicin-loaded human serum albumin nanoparticles surface-modified with TNF-related apoptosis-inducing ligand and transferrin for targeting multiple tumor types Biomaterials 33 5 2012 1536 1546
25. M.J. Hawkins, P. Soon-Shiong, and N. Desai Protein nanoparticles as drug carriers in clinical medicine Adv Drug Deliv Rev 60 8 2008 876 885
26. G. Gong, F. Zhi, K. Wang, and et al. Fabrication of a nanocarrier system through self-assembly of plasma protein and its tumor targeting Nanotechnology 22 29 2011 295603
27. D. Ding, X. Tang, X. Cao, and et al. Novel self-assembly endows human serum albumin nanoparticles with an enhanced antitumor efficacy AAPS PharmSciTech 15 1 2014 213 222
28. J. Wu, C. Song, C. Jiang, X. Shen, Q. Qiao, and Y. Hu Nucleolin targeting AS1411 modified protein nanoparticle for antitumor drugs delivery Mol Pharm 10 2013 3555 3563
29. A. Yuan, J. Wu, C. Song, and et al. A novel self-assembly albumin nanocarrier for reducing doxorubicin-mediated cardiotoxicity J Pharm Sci 102 2013 1626 1635
30. J. Kyte, and R.F. Doolittle A simple method for displaying the hydropathic character of a protein J Mol Biol 157 1 1982 105 132
31. P.T. Gomme, K.B. McCann, and J. Bertolini Transferrin: structure, function and potential therapeutic actions Drug Discov Today 10 4 2005 267 273
32. A. Albanese, P.S. Tang, and W.C. Chan The effect of nanoparticle size, shape, and surface chemistry on biological systems Annu Rev Biomed Eng 14 2012 1 16
33. D.T. Wiley, P. Webster, A. Gale, and M.E. Davis Transcytosis and brain uptake of transferrin-containing nanoparticles by tuning avidity to transferrin receptor Proc Natl Acad Sci U S A 110 21 2013 8662 8667
34. Y. Cheng, O. Zak, P. Aisen, S.C. Harrison, and T. Walz Structure of the human transferrin receptor-transferrin complex Cell 116 4 2004 565 576
35. F. Esmaeili, R. Dinarvand, M.H. Ghahremani, and et al. Docetaxel-albumin conjugates: preparation, in vitro evaluation and biodistribution studies J Pharm Sci 98 8 2009 2718 2730
36. M.R. Green, G.M. Manikhas, S. Orlov, and et al. Abraxane, a novel Cremophor-free, albumin-bound particle form of paclitaxel for the treatment of advanced non-small-cell lung cancer Ann Oncol 17 8 2006 1263 1268
37. Y. Shen, E. Jin, B. Zhang, and et al. Prodrugs forming high drug loading multifunctional nanocapsules for intracellular cancer drug delivery J Am Chem Soc 132 12 2010 4259 4265
38. E. Rinaki, G. Valsami, and P. Macheras Quantitative biopharmaceutics classification system: the central role of dose/solubility ratio Pharm Res 20 12 2003 1917 1925