-
1
-
-
79960752879
-
Genetic association of complement receptor 1 polymorphism rs3818361 in Alzheimer's disease
-
Alzheimer's Disease Neuroimaging, I.
-
Antunez C., Boada M., Lopez-Arrieta J., Moreno-Rey C., Hernandez I., Marin J., Gayan J., Gonzalez-Perez A., Real L.M., Alegret M., Tarraga L., Ramirez-Lorca R., Ruiz A. Genetic association of complement receptor 1 polymorphism rs3818361 in Alzheimer's disease. Alzheimer's Demen. J. Alzheimer's Assoc. 2011, 7:e124-e129. Alzheimer's Disease Neuroimaging, I.
-
(2011)
Alzheimer's Demen. J. Alzheimer's Assoc.
, vol.7
, pp. e124-e129
-
-
Antunez, C.1
Boada, M.2
Lopez-Arrieta, J.3
Moreno-Rey, C.4
Hernandez, I.5
Marin, J.6
Gayan, J.7
Gonzalez-Perez, A.8
Real, L.M.9
Alegret, M.10
Tarraga, L.11
Ramirez-Lorca, R.12
Ruiz, A.13
-
2
-
-
84944937240
-
Apolipoprotein E is a ligand for triggering receptor expressed on myeloid cells 2 (TREM2)
-
Atagi Y., Liu C.C., Painter M.M., Chen X.F., Verbeeck C., Zheng H., Li X., Rademakers R., Kang S.S., Xu H., Younkin S., Das P., Fryer J.D., Bu G. Apolipoprotein E is a ligand for triggering receptor expressed on myeloid cells 2 (TREM2). J. Biol. Chem. 2015, 290:26043-26050.
-
(2015)
J. Biol. Chem.
, vol.290
, pp. 26043-26050
-
-
Atagi, Y.1
Liu, C.C.2
Painter, M.M.3
Chen, X.F.4
Verbeeck, C.5
Zheng, H.6
Li, X.7
Rademakers, R.8
Kang, S.S.9
Xu, H.10
Younkin, S.11
Das, P.12
Fryer, J.D.13
Bu, G.14
-
3
-
-
84944937159
-
The triggering receptor expressed on myeloid cells 2 binds apolipoprotein E
-
Bailey C.C., DeVaux L.B., Farzan M. The triggering receptor expressed on myeloid cells 2 binds apolipoprotein E. J. Biol. Chem. 2015, 290:26033-26042.
-
(2015)
J. Biol. Chem.
, vol.290
, pp. 26033-26042
-
-
Bailey, C.C.1
DeVaux, L.B.2
Farzan, M.3
-
4
-
-
84903366979
-
Missense variant in TREML2 protects against Alzheimer's disease
-
Group, C.S., consortium, E.consortium, E., Alzheimer's Disease Genetic, C.Alzheimer's Disease Genetic, C., Alzheimer's Disease Neuroimaging, I.Alzheimer's Disease Neuroimaging, I., Consortium, G.Consortium, G.
-
Benitez B.A., Jin S.C., Guerreiro R., Graham R., Lord J., Harold D., Sims R., Lambert J.C., Gibbs J.R., Bras J., Sassi C., Harari O., Bertelsen S., Lupton M.K., Powell J., Bellenguez C., Brown K., Medway C., Haddick P.C., van der Brug M.P., Bhangale T., Ortmann W., Behrens T., Mayeux R., Pericak-Vance M.A., Farrer L.A., Schellenberg G.D., Haines J.L., Turton J., Braae A., Barber I., Fagan A.M., Holtzman D.M., Morris J.C., Williams J., Kauwe J.S., Amouyel P., Morgan K., Singleton A., Hardy J., Goate A.M., Cruchaga C. Missense variant in TREML2 protects against Alzheimer's disease. Neurobiol. Aging 2014, 35:1510.e19-1510.e26. Group, C.S., consortium, E.consortium, E., Alzheimer's Disease Genetic, C.Alzheimer's Disease Genetic, C., Alzheimer's Disease Neuroimaging, I.Alzheimer's Disease Neuroimaging, I., Consortium, G.Consortium, G.
-
(2014)
Neurobiol. Aging
, vol.35
, pp. 1510.e19-1510.e26
-
-
Benitez, B.A.1
Jin, S.C.2
Guerreiro, R.3
Graham, R.4
Lord, J.5
Harold, D.6
Sims, R.7
Lambert, J.C.8
Gibbs, J.R.9
Bras, J.10
Sassi, C.11
Harari, O.12
Bertelsen, S.13
Lupton, M.K.14
Powell, J.15
Bellenguez, C.16
Brown, K.17
Medway, C.18
Haddick, P.C.19
van der Brug, M.P.20
Bhangale, T.21
Ortmann, W.22
Behrens, T.23
Mayeux, R.24
Pericak-Vance, M.A.25
Farrer, L.A.26
Schellenberg, G.D.27
Haines, J.L.28
Turton, J.29
Braae, A.30
Barber, I.31
Fagan, A.M.32
Holtzman, D.M.33
Morris, J.C.34
Williams, J.35
Kauwe, J.S.36
Amouyel, P.37
Morgan, K.38
Singleton, A.39
Hardy, J.40
Goate, A.M.41
Cruchaga, C.42
more..
-
5
-
-
18744430888
-
Protective effect of apoE epsilon 2 in Alzheimer's disease
-
Benjamin R., Leake A., McArthur F.K., Ince P.G., Candy J.M., Edwardson J.A., Morris C.M., Bjertness E. Protective effect of apoE epsilon 2 in Alzheimer's disease. Lancet 1994, 344:473.
-
(1994)
Lancet
, vol.344
, pp. 473
-
-
Benjamin, R.1
Leake, A.2
McArthur, F.K.3
Ince, P.G.4
Candy, J.M.5
Edwardson, J.A.6
Morris, C.M.7
Bjertness, E.8
-
6
-
-
84973094194
-
Controlling the false discovery rate: a practical and powerful approach to multiple testing
-
Benjamini Y., Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. R. Stat. Soc. Ser. B (methodological) 1995, 57:289-300.
-
(1995)
J. R. Stat. Soc. Ser. B (methodological)
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
8
-
-
84951263350
-
Genomic DNA copy number aberrations, histological diagnosis, oral subsite and aneuploidy in OPMDs/OSCCs
-
Castagnola P., Zoppoli G., Gandolfo S., Monticone M., Malacarne D., Cirmena G., Brown D., Aiello C., Maffei M., Marino R., Giaretti W., Pentenero M. Genomic DNA copy number aberrations, histological diagnosis, oral subsite and aneuploidy in OPMDs/OSCCs. PLoS One 2015, 10:e0142294.
-
(2015)
PLoS One
, vol.10
, pp. e0142294
-
-
Castagnola, P.1
Zoppoli, G.2
Gandolfo, S.3
Monticone, M.4
Malacarne, D.5
Cirmena, G.6
Brown, D.7
Aiello, C.8
Maffei, M.9
Marino, R.10
Giaretti, W.11
Pentenero, M.12
-
9
-
-
84930619194
-
PROVEAN web server: a tool to predict the functional effect of amino acid substitutions and indels
-
Choi Y., Chan A.P. PROVEAN web server: a tool to predict the functional effect of amino acid substitutions and indels. Bioinformatics 2015, 31:2745-2747.
-
(2015)
Bioinformatics
, vol.31
, pp. 2745-2747
-
-
Choi, Y.1
Chan, A.P.2
-
10
-
-
78651237647
-
Identifying a high fraction of the human genome to be under selective constraint using GERP++
-
Davydov E.V., Goode D.L., Sirota M., Cooper G.M., Sidow A., Batzoglou S. Identifying a high fraction of the human genome to be under selective constraint using GERP++. PLoS Comput. Biol. 2010, 6:e1001025.
-
(2010)
PLoS Comput. Biol.
, vol.6
, pp. e1001025
-
-
Davydov, E.V.1
Goode, D.L.2
Sirota, M.3
Cooper, G.M.4
Sidow, A.5
Batzoglou, S.6
-
11
-
-
70349670733
-
Genome-wide association study of exercise behavior in Dutch and American adults
-
De Moor M.H., Liu Y.J., Boomsma D.I., Li J., Hamilton J.J., Hottenga J.J., Levy S., Liu X.G., Pei Y.F., Posthuma D., Recker R.R., Sullivan P.F., Wang L., Willemsen G., Yan H., De Geus E.J., Deng H.W. Genome-wide association study of exercise behavior in Dutch and American adults. Med. Sci. Sports Exerc. 2009, 41:1887-1895.
-
(2009)
Med. Sci. Sports Exerc.
, vol.41
, pp. 1887-1895
-
-
De Moor, M.H.1
Liu, Y.J.2
Boomsma, D.I.3
Li, J.4
Hamilton, J.J.5
Hottenga, J.J.6
Levy, S.7
Liu, X.G.8
Pei, Y.F.9
Posthuma, D.10
Recker, R.R.11
Sullivan, P.F.12
Wang, L.13
Willemsen, G.14
Yan, H.15
De Geus, E.J.16
Deng, H.W.17
-
12
-
-
79955483667
-
A framework for variation discovery and genotyping using next-generation DNA sequencing data
-
DePristo M.A., Banks E., Poplin R., Garimella K.V., Maguire J.R., Hartl C., Philippakis A.A., del Angel G., Rivas M.A., Hanna M., McKenna A., Fennell T.J., Kernytsky A.M., Sivachenko A.Y., Cibulskis K., Gabriel S.B., Altshuler D., Daly M.J. A framework for variation discovery and genotyping using next-generation DNA sequencing data. Nat. Genet. 2011, 43:491-498.
-
(2011)
Nat. Genet.
, vol.43
, pp. 491-498
-
-
DePristo, M.A.1
Banks, E.2
Poplin, R.3
Garimella, K.V.4
Maguire, J.R.5
Hartl, C.6
Philippakis, A.A.7
del Angel, G.8
Rivas, M.A.9
Hanna, M.10
McKenna, A.11
Fennell, T.J.12
Kernytsky, A.M.13
Sivachenko, A.Y.14
Cibulskis, K.15
Gabriel, S.B.16
Altshuler, D.17
Daly, M.J.18
-
13
-
-
84920425940
-
TREM2 analysis and increased risk of Alzheimer's disease
-
Finelli D., Rollinson S., Harris J., Jones M., Richardson A., Gerhard A., Snowden J., Mann D., Pickering-Brown S. TREM2 analysis and increased risk of Alzheimer's disease. Neurobiol. Aging 2015, 36:546.e9-546.e13.
-
(2015)
Neurobiol. Aging
, vol.36
, pp. 546.e9-546.e13
-
-
Finelli, D.1
Rollinson, S.2
Harris, J.3
Jones, M.4
Richardson, A.5
Gerhard, A.6
Snowden, J.7
Mann, D.8
Pickering-Brown, S.9
-
14
-
-
84920422782
-
Mutation analysis of patients with neurodegenerative disorders using NeuroX array
-
Ghani M., Lang A.E., Zinman L., Nacmias B., Sorbi S., Bessi V., Tedde A., Tartaglia M.C., Surace E.I., Sato C., Moreno D., Xi Z., Hung R., Nalls M.A., Singleton A., St George-Hyslop P., Rogaeva E. Mutation analysis of patients with neurodegenerative disorders using NeuroX array. Neurobiol. Aging 2015, 36:545.e9-545.e14.
-
(2015)
Neurobiol. Aging
, vol.36
, pp. 545.e9-545.e14
-
-
Ghani, M.1
Lang, A.E.2
Zinman, L.3
Nacmias, B.4
Sorbi, S.5
Bessi, V.6
Tedde, A.7
Tartaglia, M.C.8
Surace, E.I.9
Sato, C.10
Moreno, D.11
Xi, Z.12
Hung, R.13
Nalls, M.A.14
Singleton, A.15
St George-Hyslop, P.16
Rogaeva, E.17
-
15
-
-
84920497801
-
Autosomal dominant Alzheimer's disease: underlying causes
-
Springer, London, D. Galimberti, E. Scarpini (Eds.)
-
Ghani M., Rogaeva E. Autosomal dominant Alzheimer's disease: underlying causes. Neurodegenerative Diseases 2014, 27-47. Springer, London. D. Galimberti, E. Scarpini (Eds.).
-
(2014)
Neurodegenerative Diseases
, pp. 27-47
-
-
Ghani, M.1
Rogaeva, E.2
-
16
-
-
84872057940
-
TREM2 variants in Alzheimer's disease
-
Alzheimer Genetic Analysis, G
-
Guerreiro R., Wojtas A., Bras J., Carrasquillo M., Rogaeva E., Majounie E., Cruchaga C., Sassi C., Kauwe J.S., Younkin S., Hazrati L., Collinge J., Pocock J., Lashley T., Williams J., Lambert J.C., Amouyel P., Goate A., Rademakers R., Morgan K., Powell J., St George-Hyslop P., Singleton A., Hardy J. TREM2 variants in Alzheimer's disease. N. Engl. J. Med. 2013, 368:117-127. Alzheimer Genetic Analysis, G.
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 117-127
-
-
Guerreiro, R.1
Wojtas, A.2
Bras, J.3
Carrasquillo, M.4
Rogaeva, E.5
Majounie, E.6
Cruchaga, C.7
Sassi, C.8
Kauwe, J.S.9
Younkin, S.10
Hazrati, L.11
Collinge, J.12
Pocock, J.13
Lashley, T.14
Williams, J.15
Lambert, J.C.16
Amouyel, P.17
Goate, A.18
Rademakers, R.19
Morgan, K.20
Powell, J.21
St George-Hyslop, P.22
Singleton, A.23
Hardy, J.24
more..
-
17
-
-
84906303546
-
CD20+inflammatory T-cells are present in blood and brain of multiple sclerosis patients and can be selectively targeted for apoptotic elimination
-
Holley J.E., Bremer E., Kendall A.C., de Bruyn M., Helfrich W., Tarr J.M., Newcombe J., Gutowski N.J., Eggleton P. CD20+inflammatory T-cells are present in blood and brain of multiple sclerosis patients and can be selectively targeted for apoptotic elimination. Mult. Scler. Relat. Disord. 2014, 3:650-658.
-
(2014)
Mult. Scler. Relat. Disord.
, vol.3
, pp. 650-658
-
-
Holley, J.E.1
Bremer, E.2
Kendall, A.C.3
de Bruyn, M.4
Helfrich, W.5
Tarr, J.M.6
Newcombe, J.7
Gutowski, N.J.8
Eggleton, P.9
-
18
-
-
79955484414
-
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
-
Alzheimer's Disease Neuroimaging, I., consortium, C.consortium, C., consortium, E.consortium, E.
-
Hollingworth P., Harold D., Sims R., Gerrish A., Lambert J.C., Carrasquillo M.M., Abraham R., Hamshere M.L., Pahwa J.S., Moskvina V., Dowzell K., Jones N., Stretton A., Thomas C., Richards A., Ivanov D., Widdowson C., Chapman J., Lovestone S., Powell J., Proitsi P., Lupton M.K., Brayne C., Rubinsztein D.C., Gill M., Lawlor B., Lynch A., Brown K.S., Passmore P.A., Craig D., McGuinness B., Todd S., Holmes C., Mann D., Smith A.D., Beaumont H., Warden D., Wilcock G., Love S., Kehoe P.G., Hooper N.M., Vardy E.R., Hardy J., Mead S., Fox N.C., Rossor M., Collinge J., Maier W., Jessen F., Ruther E., Schurmann B., Heun R., Kolsch H., van den Bussche H., Heuser I., Kornhuber J., Wiltfang J., Dichgans M., Frolich L., Hampel H., Gallacher J., Hull M., Rujescu D., Giegling I., Goate A.M., Kauwe J.S., Cruchaga C., Nowotny P., Morris J.C., Mayo K., Sleegers K., Bettens K., Engelborghs S., De Deyn P.P., Van Broeckhoven C., Livingston G., Bass N.J., Gurling H., McQuillin A., Gwilliam R., Deloukas P., Al-Chalabi A., Shaw C.E., Tsolaki M., Singleton A.B., Guerreiro R., Muhleisen T.W., Nothen M.M., Moebus S., Jockel K.H., Klopp N., Wichmann H.E., Pankratz V.S., Sando S.B., Aasly J.O., Barcikowska M., Wszolek Z.K., Dickson D.W., Graff-Radford N.R., Petersen R.C., van Duijn C.M., Breteler M.M., Ikram M.A., DeStefano A.L., Fitzpatrick A.L., Lopez O., Launer L.J., Seshadri S., Berr C., Campion D., Epelbaum J., Dartigues J.F., Tzourio C., Alperovitch A., Lathrop M., Feulner T.M., Friedrich P., Riehle C., Krawczak M., Schreiber S., Mayhaus M., Nicolhaus S., Wagenpfeil S., Steinberg S., Stefansson H., Stefansson K., Snaedal J., Bjornsson S., Jonsson P.V., Chouraki V., Genier-Boley B., Hiltunen M., Soininen H., Combarros O., Zelenika D., Delepine M., Bullido M.J., Pasquier F., Mateo I., Frank-Garcia A., Porcellini E., Hanon O., Coto E., Alvarez V., Bosco P., Siciliano G., Mancuso M., Panza F., Solfrizzi V., Nacmias B., Sorbi S., Bossu P., Piccardi P., Arosio B., Annoni G., Seripa D., Pilotto A., Scarpini E., Galimberti D., Brice A., Hannequin D., Licastro F., Jones L., Holmans P.A., Jonsson T., Riemenschneider M., Morgan K., Younkin S.G., Owen M.J., O'Donovan M., Amouyel P., Williams J. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat. Genet. 2011, 43:429-435. Alzheimer's Disease Neuroimaging, I., consortium, C.consortium, C., consortium, E.consortium, E.
-
(2011)
Nat. Genet.
, vol.43
, pp. 429-435
-
-
Hollingworth, P.1
Harold, D.2
Sims, R.3
Gerrish, A.4
Lambert, J.C.5
Carrasquillo, M.M.6
Abraham, R.7
Hamshere, M.L.8
Pahwa, J.S.9
Moskvina, V.10
Dowzell, K.11
Jones, N.12
Stretton, A.13
Thomas, C.14
Richards, A.15
Ivanov, D.16
Widdowson, C.17
Chapman, J.18
Lovestone, S.19
Powell, J.20
Proitsi, P.21
Lupton, M.K.22
Brayne, C.23
Rubinsztein, D.C.24
Gill, M.25
Lawlor, B.26
Lynch, A.27
Brown, K.S.28
Passmore, P.A.29
Craig, D.30
McGuinness, B.31
Todd, S.32
Holmes, C.33
Mann, D.34
Smith, A.D.35
Beaumont, H.36
Warden, D.37
Wilcock, G.38
Love, S.39
Kehoe, P.G.40
Hooper, N.M.41
Vardy, E.R.42
Hardy, J.43
Mead, S.44
Fox, N.C.45
Rossor, M.46
Collinge, J.47
Maier, W.48
Jessen, F.49
Ruther, E.50
Schurmann, B.51
Heun, R.52
Kolsch, H.53
van den Bussche, H.54
Heuser, I.55
Kornhuber, J.56
Wiltfang, J.57
Dichgans, M.58
Frolich, L.59
Hampel, H.60
Gallacher, J.61
Hull, M.62
Rujescu, D.63
Giegling, I.64
Goate, A.M.65
Kauwe, J.S.66
Cruchaga, C.67
Nowotny, P.68
Morris, J.C.69
Mayo, K.70
Sleegers, K.71
Bettens, K.72
Engelborghs, S.73
De Deyn, P.P.74
Van Broeckhoven, C.75
Livingston, G.76
Bass, N.J.77
Gurling, H.78
McQuillin, A.79
Gwilliam, R.80
Deloukas, P.81
Al-Chalabi, A.82
Shaw, C.E.83
Tsolaki, M.84
Singleton, A.B.85
Guerreiro, R.86
Muhleisen, T.W.87
Nothen, M.M.88
Moebus, S.89
Jockel, K.H.90
Klopp, N.91
Wichmann, H.E.92
Pankratz, V.S.93
Sando, S.B.94
Aasly, J.O.95
Barcikowska, M.96
Wszolek, Z.K.97
Dickson, D.W.98
Graff-Radford, N.R.99
more..
-
19
-
-
84864471159
-
A mutation in APP protects against Alzheimer's disease and age-related cognitive decline
-
Jonsson T., Atwal J.K., Steinberg S., Snaedal J., Jonsson P.V., Bjornsson S., Stefansson H., Sulem P., Gudbjartsson D., Maloney J., Hoyte K., Gustafson A., Liu Y., Lu Y., Bhangale T., Graham R.R., Huttenlocher J., Bjornsdottir G., Andreassen O.A., Jönsson E.G., Palotie A., Behrens T.W., Magnusson O.T., Kong A., Thorsteinsdottir U., Watts R.J., Stefansson K. A mutation in APP protects against Alzheimer's disease and age-related cognitive decline. Nature 2012, 488:96-99.
-
(2012)
Nature
, vol.488
, pp. 96-99
-
-
Jonsson, T.1
Atwal, J.K.2
Steinberg, S.3
Snaedal, J.4
Jonsson, P.V.5
Bjornsson, S.6
Stefansson, H.7
Sulem, P.8
Gudbjartsson, D.9
Maloney, J.10
Hoyte, K.11
Gustafson, A.12
Liu, Y.13
Lu, Y.14
Bhangale, T.15
Graham, R.R.16
Huttenlocher, J.17
Bjornsdottir, G.18
Andreassen, O.A.19
Jönsson, E.G.20
Palotie, A.21
Behrens, T.W.22
Magnusson, O.T.23
Kong, A.24
Thorsteinsdottir, U.25
Watts, R.J.26
Stefansson, K.27
more..
-
20
-
-
84872088087
-
Variant of TREM2 associated with the risk of Alzheimer's disease
-
Jonsson T., Stefansson H., Steinberg S., Jonsdottir I., Jonsson P.V., Snaedal J., Bjornsson S., Huttenlocher J., Levey A.I., Lah J.J., Rujescu D., Hampel H., Giegling I., Andreassen O.A., Engedal K., Ulstein I., Djurovic S., Ibrahim-Verbaas C., Hofman A., Ikram M.A., van Duijn C.M., Thorsteinsdottir U., Kong A., Stefansson K. Variant of TREM2 associated with the risk of Alzheimer's disease. N. Engl. J. Med. 2013, 368:107-116.
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 107-116
-
-
Jonsson, T.1
Stefansson, H.2
Steinberg, S.3
Jonsdottir, I.4
Jonsson, P.V.5
Snaedal, J.6
Bjornsson, S.7
Huttenlocher, J.8
Levey, A.I.9
Lah, J.J.10
Rujescu, D.11
Hampel, H.12
Giegling, I.13
Andreassen, O.A.14
Engedal, K.15
Ulstein, I.16
Djurovic, S.17
Ibrahim-Verbaas, C.18
Hofman, A.19
Ikram, M.A.20
van Duijn, C.M.21
Thorsteinsdottir, U.22
Kong, A.23
Stefansson, K.24
more..
-
21
-
-
84870584668
-
Expression of novel Alzheimer's disease risk genes in control and Alzheimer's disease brains
-
Karch C.M., Jeng A.T., Nowotny P., Cady J., Cruchaga C., Goate A.M. Expression of novel Alzheimer's disease risk genes in control and Alzheimer's disease brains. PLoS One 2012, 7:e50976.
-
(2012)
PLoS One
, vol.7
, pp. e50976
-
-
Karch, C.M.1
Jeng, A.T.2
Nowotny, P.3
Cady, J.4
Cruchaga, C.5
Goate, A.M.6
-
22
-
-
84938912653
-
R47H variant of TREM2 associated with Alzheimer disease in a large late-onset family: clinical, genetic, and neuropathological study
-
Korvatska O., Leverenz J.B., Jayadev S., McMillan P., Kurtz I., Guo X., Rumbaugh M., Matsushita M., Girirajan S., Dorschner M.O., Kiianitsa K., Yu C.E., Brkanac Z., Garden G.A., Raskind W.H., Bird T.D. R47H variant of TREM2 associated with Alzheimer disease in a large late-onset family: clinical, genetic, and neuropathological study. JAMA Neurol. 2015, 72:920-927.
-
(2015)
JAMA Neurol.
, vol.72
, pp. 920-927
-
-
Korvatska, O.1
Leverenz, J.B.2
Jayadev, S.3
McMillan, P.4
Kurtz, I.5
Guo, X.6
Rumbaugh, M.7
Matsushita, M.8
Girirajan, S.9
Dorschner, M.O.10
Kiianitsa, K.11
Yu, C.E.12
Brkanac, Z.13
Garden, G.A.14
Raskind, W.H.15
Bird, T.D.16
-
23
-
-
74949085764
-
CD20 deficiency in humans results in impaired T cell-independent antibody responses
-
Kuijpers T.W., Bende R.J., Baars P.A., Grummels A., Derks I.A., Dolman K.M., Beaumont T., Tedder T.F., van Noesel C.J., Eldering E., van Lier R.A. CD20 deficiency in humans results in impaired T cell-independent antibody responses. J. Clin. Invest. 2010, 120:214-222.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 214-222
-
-
Kuijpers, T.W.1
Bende, R.J.2
Baars, P.A.3
Grummels, A.4
Derks, I.A.5
Dolman, K.M.6
Beaumont, T.7
Tedder, T.F.8
van Noesel, C.J.9
Eldering, E.10
van Lier, R.A.11
-
24
-
-
84888317489
-
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
-
European Alzheimer's Disease, I., Genetic, Environmental Risk in Alzheimer's, D.Genetic, Environmental Risk in Alzheimer's, D., Alzheimer's Disease Genetic, C.Alzheimer's Disease Genetic, C., Cohorts for, H.Cohorts for, H., Aging Research in Genomic, E.Aging Research in Genomic, E.
-
Lambert J.C., Ibrahim-Verbaas C.A., Harold D., Naj A.C., Sims R., Bellenguez C., DeStafano A.L., Bis J.C., Beecham G.W., Grenier-Boley B., Russo G., Thorton-Wells T.A., Jones N., Smith A.V., Chouraki V., Thomas C., Ikram M.A., Zelenika D., Vardarajan B.N., Kamatani Y., Lin C.F., Gerrish A., Schmidt H., Kunkle B., Dunstan M.L., Ruiz A., Bihoreau M.T., Choi S.H., Reitz C., Pasquier F., Cruchaga C., Craig D., Amin N., Berr C., Lopez O.L., De Jager P.L., Deramecourt V., Johnston J.A., Evans D., Lovestone S., Letenneur L., Moron F.J., Rubinsztein D.C., Eiriksdottir G., Sleegers K., Goate A.M., Fievet N., Huentelman M.W., Gill M., Brown K., Kamboh M.I., Keller L., Barberger-Gateau P., McGuiness B., Larson E.B., Green R., Myers A.J., Dufouil C., Todd S., Wallon D., Love S., Rogaeva E., Gallacher J., St George-Hyslop P., Clarimon J., Lleo A., Bayer A., Tsuang D.W., Yu L., Tsolaki M., Bossu P., Spalletta G., Proitsi P., Collinge J., Sorbi S., Sanchez-Garcia F., Fox N.C., Hardy J., Deniz Naranjo M.C., Bosco P., Clarke R., Brayne C., Galimberti D., Mancuso M., Matthews F., Moebus S., Mecocci P., Del Zompo M., Maier W., Hampel H., Pilotto A., Bullido M., Panza F., Caffarra P., Nacmias B., Gilbert J.R., Mayhaus M., Lannefelt L., Hakonarson H., Pichler S., Carrasquillo M.M., Ingelsson M., Beekly D., Alvarez V., Zou F., Valladares O., Younkin S.G., Coto E., Hamilton-Nelson K.L., Gu W., Razquin C., Pastor P., Mateo I., Owen M.J., Faber K.M., Jonsson P.V., Combarros O., O'Donovan M.C., Cantwell L.B., Soininen H., Blacker D., Mead S., Mosley T.H., Bennett D.A., Harris T.B., Fratiglioni L., Holmes C., de Bruijn R.F., Passmore P., Montine T.J., Bettens K., Rotter J.I., Brice A., Morgan K., Foroud T.M., Kukull W.A., Hannequin D., Powell J.F., Nalls M.A., Ritchie K., Lunetta K.L., Kauwe J.S., Boerwinkle E., Riemenschneider M., Boada M., Hiltuenen M., Martin E.R., Schmidt R., Rujescu D., Wang L.S., Dartigues J.F., Mayeux R., Tzourio C., Hofman A., Nothen M.M., Graff C., Psaty B.M., Jones L., Haines J.L., Holmans P.A., Lathrop M., Pericak-Vance M.A., Launer L.J., Farrer L.A., van Duijn C.M., Van Broeckhoven C., Moskvina V., Seshadri S., Williams J., Schellenberg G.D., Amouyel P. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat. Genet. 2013, 45:1452-1458. European Alzheimer's Disease, I., Genetic, Environmental Risk in Alzheimer's, D.Genetic, Environmental Risk in Alzheimer's, D., Alzheimer's Disease Genetic, C.Alzheimer's Disease Genetic, C., Cohorts for, H.Cohorts for, H., Aging Research in Genomic, E.Aging Research in Genomic, E.
-
(2013)
Nat. Genet.
, vol.45
, pp. 1452-1458
-
-
Lambert, J.C.1
Ibrahim-Verbaas, C.A.2
Harold, D.3
Naj, A.C.4
Sims, R.5
Bellenguez, C.6
DeStafano, A.L.7
Bis, J.C.8
Beecham, G.W.9
Grenier-Boley, B.10
Russo, G.11
Thorton-Wells, T.A.12
Jones, N.13
Smith, A.V.14
Chouraki, V.15
Thomas, C.16
Ikram, M.A.17
Zelenika, D.18
Vardarajan, B.N.19
Kamatani, Y.20
Lin, C.F.21
Gerrish, A.22
Schmidt, H.23
Kunkle, B.24
Dunstan, M.L.25
Ruiz, A.26
Bihoreau, M.T.27
Choi, S.H.28
Reitz, C.29
Pasquier, F.30
Cruchaga, C.31
Craig, D.32
Amin, N.33
Berr, C.34
Lopez, O.L.35
De Jager, P.L.36
Deramecourt, V.37
Johnston, J.A.38
Evans, D.39
Lovestone, S.40
Letenneur, L.41
Moron, F.J.42
Rubinsztein, D.C.43
Eiriksdottir, G.44
Sleegers, K.45
Goate, A.M.46
Fievet, N.47
Huentelman, M.W.48
Gill, M.49
Brown, K.50
Kamboh, M.I.51
Keller, L.52
Barberger-Gateau, P.53
McGuiness, B.54
Larson, E.B.55
Green, R.56
Myers, A.J.57
Dufouil, C.58
Todd, S.59
Wallon, D.60
Love, S.61
Rogaeva, E.62
Gallacher, J.63
St George-Hyslop, P.64
Clarimon, J.65
Lleo, A.66
Bayer, A.67
Tsuang, D.W.68
Yu, L.69
Tsolaki, M.70
Bossu, P.71
Spalletta, G.72
Proitsi, P.73
Collinge, J.74
Sorbi, S.75
Sanchez-Garcia, F.76
Fox, N.C.77
Hardy, J.78
Deniz Naranjo, M.C.79
Bosco, P.80
Clarke, R.81
Brayne, C.82
Galimberti, D.83
Mancuso, M.84
Matthews, F.85
Moebus, S.86
Mecocci, P.87
Del Zompo, M.88
Maier, W.89
Hampel, H.90
Pilotto, A.91
Bullido, M.92
Panza, F.93
Caffarra, P.94
Nacmias, B.95
Gilbert, J.R.96
Mayhaus, M.97
Lannefelt, L.98
Hakonarson, H.99
more..
-
25
-
-
67649884743
-
Fast and accurate short read alignment with Burrows-Wheeler transform
-
Li H., Durbin R. Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 2009, 25:1754-1760.
-
(2009)
Bioinformatics
, vol.25
, pp. 1754-1760
-
-
Li, H.1
Durbin, R.2
-
26
-
-
0035263570
-
Identification of a CD20-, FcepsilonRIbeta-, and HTm4-related gene family: sixteen new MS4A family members expressed in human and mouse
-
Liang Y., Tedder T.F. Identification of a CD20-, FcepsilonRIbeta-, and HTm4-related gene family: sixteen new MS4A family members expressed in human and mouse. Genomics 2001, 72:119-127.
-
(2001)
Genomics
, vol.72
, pp. 119-127
-
-
Liang, Y.1
Tedder, T.F.2
-
27
-
-
84952631227
-
The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease
-
Consortium, S.
-
Lill C.M., Rengmark A., Pihlstrom L., Fogh I., Shatunov A., Sleiman P.M., Wang L.S., Liu T., Lassen C.F., Meissner E., Alexopoulos P., Calvo A., Chio A., Dizdar N., Faltraco F., Forsgren L., Kirchheiner J., Kurz A., Larsen J.P., Liebsch M., Linder J., Morrison K.E., Nissbrandt H., Otto M., Pahnke J., Partch A., Restagno G., Rujescu D., Schnack C., Shaw C.E., Shaw P.J., Tumani H., Tysnes O.B., Valladares O., Silani V., van den Berg L.H., van Rheenen W., Veldink J.H., Lindenberger U., Steinhagen-Thiessen E., Teipel S., Perneczky R., Hakonarson H., Hampel H., von Arnim C.A., Olsen J.H., Van Deerlin V.M., Al-Chalabi A., Toft M., Ritz B., Bertram L. The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease. Alzheimer's Demen. 2015, 11:1407-1416. Consortium, S.
-
(2015)
Alzheimer's Demen.
, vol.11
, pp. 1407-1416
-
-
Lill, C.M.1
Rengmark, A.2
Pihlstrom, L.3
Fogh, I.4
Shatunov, A.5
Sleiman, P.M.6
Wang, L.S.7
Liu, T.8
Lassen, C.F.9
Meissner, E.10
Alexopoulos, P.11
Calvo, A.12
Chio, A.13
Dizdar, N.14
Faltraco, F.15
Forsgren, L.16
Kirchheiner, J.17
Kurz, A.18
Larsen, J.P.19
Liebsch, M.20
Linder, J.21
Morrison, K.E.22
Nissbrandt, H.23
Otto, M.24
Pahnke, J.25
Partch, A.26
Restagno, G.27
Rujescu, D.28
Schnack, C.29
Shaw, C.E.30
Shaw, P.J.31
Tumani, H.32
Tysnes, O.B.33
Valladares, O.34
Silani, V.35
van den Berg, L.H.36
van Rheenen, W.37
Veldink, J.H.38
Lindenberger, U.39
Steinhagen-Thiessen, E.40
Teipel, S.41
Perneczky, R.42
Hakonarson, H.43
Hampel, H.44
von Arnim, C.A.45
Olsen, J.H.46
Van Deerlin, V.M.47
Al-Chalabi, A.48
Toft, M.49
Ritz, B.50
Bertram, L.51
more..
-
28
-
-
84930577222
-
Alzheimer disease: the involvement of TREM2 R47H variant in Alzheimer disease confirmed, but mechanisms remain elusive
-
Malkki H. Alzheimer disease: the involvement of TREM2 R47H variant in Alzheimer disease confirmed, but mechanisms remain elusive. Nat. Rev. Neurol. 2015, 11:307.
-
(2015)
Nat. Rev. Neurol.
, vol.11
, pp. 307
-
-
Malkki, H.1
-
29
-
-
84922881812
-
Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models
-
Martiskainen H., Viswanathan J., Nykanen N.P., Kurki M., Helisalmi S., Natunen T., Sarajarvi T., Kurkinen K.M., Pursiheimo J.P., Rauramaa T., Alafuzoff I., Jaaskelainen J.E., Leinonen V., Soininen H., Haapasalo A., Huttunen H.J., Hiltunen M. Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models. Neurobiol. Aging 2015, 36:1221.e15-1221.e28.
-
(2015)
Neurobiol. Aging
, vol.36
, pp. 1221.e15-1221.e28
-
-
Martiskainen, H.1
Viswanathan, J.2
Nykanen, N.P.3
Kurki, M.4
Helisalmi, S.5
Natunen, T.6
Sarajarvi, T.7
Kurkinen, K.M.8
Pursiheimo, J.P.9
Rauramaa, T.10
Alafuzoff, I.11
Jaaskelainen, J.E.12
Leinonen, V.13
Soininen, H.14
Haapasalo, A.15
Huttunen, H.J.16
Hiltunen, M.17
-
30
-
-
18544390923
-
Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype
-
Paloneva J., Manninen T., Christman G., Hovanes K., Mandelin J., Adolfsson R., Bianchin M., Bird T., Miranda R., Salmaggi A., Tranebjaerg L., Konttinen Y., Peltonen L. Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype. Am. J. Hum. Genet. 2002, 71:656-662.
-
(2002)
Am. J. Hum. Genet.
, vol.71
, pp. 656-662
-
-
Paloneva, J.1
Manninen, T.2
Christman, G.3
Hovanes, K.4
Mandelin, J.5
Adolfsson, R.6
Bianchin, M.7
Bird, T.8
Miranda, R.9
Salmaggi, A.10
Tranebjaerg, L.11
Konttinen, Y.12
Peltonen, L.13
-
31
-
-
84899676806
-
Overrepresentation of glutamate signaling in Alzheimer's disease: network-based pathway enrichment using meta-analysis of genome-wide association studies
-
Alzheimer's Disease Neuroimaging, I., Group, N.-L.N.F.SGroup, N.-L.N.F.S
-
Perez-Palma E., Bustos B.I., Villaman C.F., Alarcon M.A., Avila M.E., Ugarte G.D., Reyes A.E., Opazo C., De Ferrari G.V. Overrepresentation of glutamate signaling in Alzheimer's disease: network-based pathway enrichment using meta-analysis of genome-wide association studies. PLoS One 2014, 9:e95413. Alzheimer's Disease Neuroimaging, I., Group, N.-L.N.F.SGroup, N.-L.N.F.S.
-
(2014)
PLoS One
, vol.9
, pp. e95413
-
-
Perez-Palma, E.1
Bustos, B.I.2
Villaman, C.F.3
Alarcon, M.A.4
Avila, M.E.5
Ugarte, G.D.6
Reyes, A.E.7
Opazo, C.8
De Ferrari, G.V.9
-
32
-
-
84954193258
-
Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status
-
[Epub ahead of print]
-
Piccio L., Deming Y., Del-Aguila J.L., Ghezzi L., Holtzman D.M., Fagan A.M., Fenoglio C., Galimberti D., Borroni B., Cruchaga C. Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status. Acta Neuropathol. 2016, [Epub ahead of print]. doi:10.1007/s00401-016-1533-5.
-
(2016)
Acta Neuropathol.
-
-
Piccio, L.1
Deming, Y.2
Del-Aguila, J.L.3
Ghezzi, L.4
Holtzman, D.M.5
Fagan, A.M.6
Fenoglio, C.7
Galimberti, D.8
Borroni, B.9
Cruchaga, C.10
-
33
-
-
84887247060
-
Alzheimer's disease susceptibility variants in the MS4A6A gene are associated with altered levels of MS4A6A expression in blood
-
AddNeuroMed, C
-
Proitsi P., Lee S.H., Lunnon K., Keohane A., Powell J., Troakes C., Al-Sarraj S., Furney S., Soininen H., Kloszewska I., Mecocci P., Tsolaki M., Vellas B., Lovestone S., Hodges A. Alzheimer's disease susceptibility variants in the MS4A6A gene are associated with altered levels of MS4A6A expression in blood. Neurobiol. Aging 2014, 35:279-290. AddNeuroMed, C.
-
(2014)
Neurobiol. Aging
, vol.35
, pp. 279-290
-
-
Proitsi, P.1
Lee, S.H.2
Lunnon, K.3
Keohane, A.4
Powell, J.5
Troakes, C.6
Al-Sarraj, S.7
Furney, S.8
Soininen, H.9
Kloszewska, I.10
Mecocci, P.11
Tsolaki, M.12
Vellas, B.13
Lovestone, S.14
Hodges, A.15
-
34
-
-
84940655348
-
More evidence for association of a rare TREM2 mutation (R47H) with Alzheimer's disease risk
-
Rosenthal S.L., Bamne M.N., Wang X., Berman S., Snitz B.E., Klunk W.E., Sweet R.A., Demirci F.Y., Lopez O.L., Kamboh M.I. More evidence for association of a rare TREM2 mutation (R47H) with Alzheimer's disease risk. Neurobiol. Aging 2015, 36:2443.e21-2443.e26.
-
(2015)
Neurobiol. Aging
, vol.36
, pp. 2443.e21-2443.e26
-
-
Rosenthal, S.L.1
Bamne, M.N.2
Wang, X.3
Berman, S.4
Snitz, B.E.5
Klunk, W.E.6
Sweet, R.A.7
Demirci, F.Y.8
Lopez, O.L.9
Kamboh, M.I.10
-
36
-
-
84896009017
-
From FastQ data to high confidence variant calls: the Genome Analysis Toolkit best practices pipeline
-
Van der Auwera G.A., Carneiro M.O., Hartl C., Poplin R., Del Angel G., Levy-Moonshine A., Jordan T., Shakir K., Roazen D., Thibault J., Banks E., Garimella K.V., Altshuler D., Gabriel S., DePristo M.A. From FastQ data to high confidence variant calls: the Genome Analysis Toolkit best practices pipeline. Curr. Protoc. Bioinformatics 2013, 11:11.10.1-11.10.33.
-
(2013)
Curr. Protoc. Bioinformatics
, vol.11
, pp. 11.10.1-11.10.33
-
-
Van der Auwera, G.A.1
Carneiro, M.O.2
Hartl, C.3
Poplin, R.4
Del Angel, G.5
Levy-Moonshine, A.6
Jordan, T.7
Shakir, K.8
Roazen, D.9
Thibault, J.10
Banks, E.11
Garimella, K.V.12
Altshuler, D.13
Gabriel, S.14
DePristo, M.A.15
-
37
-
-
84939654955
-
Rare coding mutations identified by sequencing of Alzheimer disease genome-wide association studies loci
-
Vardarajan B.N., Ghani M., Kahn A., Sheikh S., Sato C., Barral S., Lee J.H., Cheng R., Reitz C., Lantigua R., Reyes-Dumeyer D., Medrano M., Jimenez-Velazquez I.Z., Rogaeva E., St George-Hyslop P., Mayeux R. Rare coding mutations identified by sequencing of Alzheimer disease genome-wide association studies loci. Ann. Neurol. 2015, 78:487-498.
-
(2015)
Ann. Neurol.
, vol.78
, pp. 487-498
-
-
Vardarajan, B.N.1
Ghani, M.2
Kahn, A.3
Sheikh, S.4
Sato, C.5
Barral, S.6
Lee, J.H.7
Cheng, R.8
Reitz, C.9
Lantigua, R.10
Reyes-Dumeyer, D.11
Medrano, M.12
Jimenez-Velazquez, I.Z.13
Rogaeva, E.14
St George-Hyslop, P.15
Mayeux, R.16
-
38
-
-
77956534324
-
ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data
-
Wang K., Li M., Hakonarson H. ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data. Nucleic Acids Res. 2010, 38:e164.
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. e164
-
-
Wang, K.1
Li, M.2
Hakonarson, H.3
-
39
-
-
84925464993
-
TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model
-
Wang Y., Cella M., Mallinson K., Ulrich J.D., Young K.L., Robinette M.L., Gilfillan S., Krishnan G.M., Sudhakar S., Zinselmeyer B.H., Holtzman D.M., Cirrito J.R., Colonna M. TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model. Cell 2015, 160:1061-1071.
-
(2015)
Cell
, vol.160
, pp. 1061-1071
-
-
Wang, Y.1
Cella, M.2
Mallinson, K.3
Ulrich, J.D.4
Young, K.L.5
Robinette, M.L.6
Gilfillan, S.7
Krishnan, G.M.8
Sudhakar, S.9
Zinselmeyer, B.H.10
Holtzman, D.M.11
Cirrito, J.R.12
Colonna, M.13
-
40
-
-
84940094599
-
DAP12 stabilizes the C-terminal fragment of the triggering receptor expressed on myeloid cells-2 (TREM2) and protects against LPS-induced pro-inflammatory response
-
Zhong L., Chen X.F., Zhang Z.L., Wang Z., Shi X.Z., Xu K., Zhang Y.W., Xu H., Bu G. DAP12 stabilizes the C-terminal fragment of the triggering receptor expressed on myeloid cells-2 (TREM2) and protects against LPS-induced pro-inflammatory response. J. Biol. Chem. 2015, 290:15866-15877.
-
(2015)
J. Biol. Chem.
, vol.290
, pp. 15866-15877
-
-
Zhong, L.1
Chen, X.F.2
Zhang, Z.L.3
Wang, Z.4
Shi, X.Z.5
Xu, K.6
Zhang, Y.W.7
Xu, H.8
Bu, G.9
|