Pharmacokinetic study of eplerenone in rats after long-term coadministration with buckwheat tea

Kaohsiung Journal of Medical Sciences

Volumn 32, Issue 4, 2016, Pages 177-184

  Zou, Liang ^a   Jia, Kun ^b   Li, Rui ^b   Wang, Ping ^c   Lin, Jun Zhi ^c   Chen, Hui Juan ^d   Zhao, Gang ^a   Peng, Lian Xin ^a  

^a CHENGDU UNIVERSITY   (China)

^b XIHUA UNIVERSITY   (China)

^c CHENGDU UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^d Sichuan Province Traditional Chinese Medicine Hospital   (China)

Author keywords

Coadministration; Eplerenone; Hypertension; Pharmacokinetics; Tartary buckwheat

Indexed keywords

DRUG METABOLIZING ENZYME; EPLERENONE; SPIRONOLACTONE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BUCKWHEAT; BUCKWHEAT TEA; CONTROLLED STUDY; DIETARY SUPPLEMENT; DRUG ABSORPTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPERTENSION; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LONG TERM SURVIVAL; MALE; MASS SPECTROMETRY; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PHARMACOKINETIC PARAMETERS; PORTAL VEIN; QUANTITATIVE ANALYSIS; RAT; SPRAGUE DAWLEY RAT; TEA; TIME TO MAXIMUM PLASMA CONCENTRATION; VALIDATION STUDY; ANALOGS AND DERIVATIVES; ANIMAL; BLOOD; CALIBRATION; CHEMISTRY; FAGOPYRUM; HERBAL TEA; REPRODUCIBILITY; SOLUTION AND SOLUBILITY; STANDARD; TIME FACTOR;

ANIMALS; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EPLERENONE; FAGOPYRUM; LIMIT OF DETECTION; MALE; MASS SPECTROMETRY; RATS, SPRAGUE-DAWLEY; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SOLUTIONS; SPIRONOLACTONE; TEAS, HERBAL; TIME FACTORS;

EID: 84964342035     PISSN: 1607551X     EISSN: 24108650     Source Type: Journal    
DOI: 10.1016/j.kjms.2016.03.004     Document Type: Article

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