-
1
-
-
84965112748
-
-
Bethesda, MD: NCI; 2011 cited 2015 Jul. 2. SEER stat fact sheets: bladder cancer about
-
Surveillance, Epidemiology, and End Results (SEER) Program [database on the Internet]. Bethesda, MD: NCI; 2011 [cited 2015 Jul. 2]. SEER stat fact sheets: bladder cancer [about 9 p.]. Available from: http://seer.cancer.gov/statfacts/html/urinb.html.
-
Surveillance, Epidemiology, and End Results (SEER) Program [Database on the Internet]
, pp. 9
-
-
-
2
-
-
67349258581
-
The present and future burden of urinary bladder cancer in the world
-
Ploeg M, Aben KK, Kiemeney LA. The present and future burden of urinary bladder cancer in the world. World J Urol 2009;27:289-93.
-
(2009)
World J Urol
, vol.27
, pp. 289-293
-
-
Ploeg, M.1
Aben, K.K.2
Kiemeney, L.A.3
-
3
-
-
0036828099
-
Bladder cancer: Epidemiology, diagnosis, and management
-
Pashos CL, Botteman MF, Laskin BL, Redaelli A. Bladder cancer: epidemiology, diagnosis, and management. Cancer Pract 2002;10:311-22.
-
(2002)
Cancer Pract
, vol.10
, pp. 311-322
-
-
Pashos, C.L.1
Botteman, M.F.2
Laskin, B.L.3
Redaelli, A.4
-
4
-
-
84880507665
-
Mutational heterogeneity in cancer and the search for new cancerassociated genes
-
Lawrence MS, Stojanov P, Polak P, Kryukov GV, Cibulskis K, Sivachenko A, et al. Mutational heterogeneity in cancer and the search for new cancerassociated genes. Nature 2013;499:214-8.
-
(2013)
Nature
, vol.499
, pp. 214-218
-
-
Lawrence, M.S.1
Stojanov, P.2
Polak, P.3
Kryukov, G.V.4
Cibulskis, K.5
Sivachenko, A.6
-
5
-
-
84862294941
-
Surveillance and treatment of non-muscle-invasive bladder cancer in the USA
-
Barocas DA, Globe DR, Colayco DC, Onyenwenyi A, Bruno AS, Bramley TJ, et al. Surveillance and treatment of non-muscle-invasive bladder cancer in the USA. Adv Urol 2012;2012:421709.
-
(2012)
Adv Urol
, vol.2012
, pp. 421709
-
-
Barocas, D.A.1
Globe, D.R.2
Colayco, D.C.3
Onyenwenyi, A.4
Bruno, A.S.5
Bramley, T.J.6
-
6
-
-
34247363602
-
Systemic chemotherapy for advanced bladder cancer: Update and controversies
-
Garcia JA, Dreicer R. Systemic chemotherapy for advanced bladder cancer: update and controversies. J Clin Oncol 2006;24:5545-51.
-
(2006)
J Clin Oncol
, vol.24
, pp. 5545-5551
-
-
Garcia, J.A.1
Dreicer, R.2
-
7
-
-
84856851592
-
Double-blind, randomized trial of docetaxel plus vandetanib versus docetaxel plus placebo in platinum-pretreated metastatic urothelial cancer
-
Choueiri TK, Ross RW, Jacobus S, Vaishampayan U, Yu EY, Quinn DI, et al. Double-blind, randomized trial of docetaxel plus vandetanib versus docetaxel plus placebo in platinum-pretreated metastatic urothelial cancer. J Clin Oncol 2012;30:507-12.
-
(2012)
J Clin Oncol
, vol.30
, pp. 507-512
-
-
Choueiri, T.K.1
Ross, R.W.2
Jacobus, S.3
Vaishampayan, U.4
Yu, E.Y.5
Quinn, D.I.6
-
8
-
-
75149128685
-
Phase III trial of vinflunine plus best supportive care compared with best supportive care alone after a platinum-containing regimen in patients with advanced transitional cell carcinoma of the urothelial tract
-
Bellmunt J, Theodore C, Demkov T, Komyakov B, Sengelov L, Daugaard G, et al. Phase III trial of vinflunine plus best supportive care compared with best supportive care alone after a platinum-containing regimen in patients with advanced transitional cell carcinoma of the urothelial tract. J Clin Oncol 2009;27:4454-61.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4454-4461
-
-
Bellmunt, J.1
Theodore, C.2
Demkov, T.3
Komyakov, B.4
Sengelov, L.5
Daugaard, G.6
-
9
-
-
33749605418
-
A phase II trial of pemetrexed plus gemcitabine in locally advanced and/or metastatic transitional cell carcinoma of the urothelium
-
von der Maase H, Lehmann J, Gravis G, Joensuu H, Geertsen PF, Gough J, et al. A phase II trial of pemetrexed plus gemcitabine in locally advanced and/or metastatic transitional cell carcinoma of the urothelium. Ann Oncol 2006;17:1533-8.
-
(2006)
Ann Oncol
, vol.17
, pp. 1533-1538
-
-
Von Der Maase, H.1
Lehmann, J.2
Gravis, G.3
Joensuu, H.4
Geertsen, P.F.5
Gough, J.6
-
10
-
-
33846581566
-
Chemotherapy for bladder cancer: Treatment guidelines for neoadjuvant chemotherapy, bladder preservation, adjuvant chemotherapy, and metastatic cancer
-
Sternberg CN, Donat SM, BellmuntJ, Millikan RE, Stadler W, De Mulder P, et al. Chemotherapy for bladder cancer: treatment guidelines for neoadjuvant chemotherapy, bladder preservation, adjuvant chemotherapy, and metastatic cancer. Urology 2007;69:62-79.
-
(2007)
Urology
, vol.69
, pp. 62-79
-
-
Sternberg, C.N.1
Donat, S.M.2
Bellmunt, J.3
Millikan, R.E.4
Stadler, W.5
De Mulder, P.6
-
11
-
-
84897022815
-
Comprehensive molecular characterization of urothelial bladder carcinoma
-
Cancer Genome Atlas Research N. Comprehensive molecular characterization of urothelial bladder carcinoma. Nature 2014;507:315-22.
-
(2014)
Nature
, vol.507
, pp. 315-322
-
-
Cancer Genome Atlas Research N1
-
12
-
-
84908233609
-
Getting personal with neoantigen-based therapeutic cancer vaccines
-
Hacohen N, Fritsch EF, Carter TA, Lander ES, WuCJ. Getting personal with neoantigen-based therapeutic cancer vaccines. Cancer Immunol Res 2013;1:11-5.
-
(2013)
Cancer Immunol Res
, vol.1
, pp. 11-15
-
-
Hacohen, N.1
Fritsch, E.F.2
Carter, T.A.3
Lander, E.S.4
Wu, C.J.5
-
13
-
-
84928761118
-
Mutational landscape determines sensitivity to PD-1 blockade in nonsmall cell lung cancer
-
Rizvi NA, Hellmann MD, Snyder A, Kvistborg P, Makarov V, Havel JJ, et al. Mutational landscape determines sensitivity to PD-1 blockade in nonsmall cell lung cancer. Science 2015;348:124-8.
-
(2015)
Science
, vol.348
, pp. 124-128
-
-
Rizvi, N.A.1
Hellmann, M.D.2
Snyder, A.3
Kvistborg, P.4
Makarov, V.5
Havel, J.J.6
-
14
-
-
84918828514
-
Genetic basis for clinical response to CTLA-4 blockade in melanoma
-
Snyder A, Makarov V, Merghoub T, YuanJ, Zaretsky JM, Desrichard A, et al. Genetic basis for clinical response to CTLA-4 blockade in melanoma. N Engl J Med 2014;371:2189-99.
-
(2014)
N Engl J Med
, vol.371
, pp. 2189-2199
-
-
Snyder, A.1
Makarov, V.2
Merghoub, T.3
Yuan, J.4
Zaretsky, J.M.5
Desrichard, A.6
-
15
-
-
84928774156
-
The future of immune checkpoint therapy
-
Sharma P, Allison JP. The future of immune checkpoint therapy. Science 2015;348:56-61.
-
(2015)
Science
, vol.348
, pp. 56-61
-
-
Sharma, P.1
Allison, J.P.2
-
16
-
-
84928770388
-
Neoantigens in cancer immunotherapy
-
Schumacher TN, Schreiber RD. Neoantigens in cancer immunotherapy. Science 2015;348:69-74.
-
(2015)
Science
, vol.348
, pp. 69-74
-
-
Schumacher, T.N.1
Schreiber, R.D.2
-
17
-
-
84928771999
-
T cell exclusion, immune privilege, and the tumor microenvironment
-
Joyce JA, Fearon DT. T cell exclusion, immune privilege, and the tumor microenvironment. Science 2015;348:74-80.
-
(2015)
Science
, vol.348
, pp. 74-80
-
-
Joyce, J.A.1
Fearon, D.T.2
-
18
-
-
0018959101
-
Bacillus Calmette-Guerin immunotherapy of superficial bladder cancer
-
Lamm DL, Thor DE, Harris SC, Reyna JA, Stogdill VD, Radwin HM. Bacillus Calmette-Guerin immunotherapy of superficial bladder cancer. J Urol 1980;124:38-40.
-
(1980)
J Urol
, vol.124
, pp. 38-40
-
-
Lamm, D.L.1
Thor, D.E.2
Harris, S.C.3
Reyna, J.A.4
Stogdill, V.D.5
Radwin, H.M.6
-
19
-
-
84897114969
-
The mechanism of action of BCG therapy for bladder cancer - A current perspective
-
Redelman-Sidi G, Glickman MS, Bochner BH. The mechanism of action of BCG therapy for bladder cancer-a current perspective. Nat Rev Urol 2014;11:153-62.
-
(2014)
Nat Rev Urol
, vol.11
, pp. 153-162
-
-
Redelman-Sidi, G.1
Glickman, M.S.2
Bochner, B.H.3
-
20
-
-
84879887890
-
Bacillus Calmette-Guerin immunotherapy for genitourinary cancer
-
Gandhi NM, Morales A, Lamm DL. Bacillus Calmette-Guerin immunotherapy for genitourinary cancer. BJU Int 2013;112:288-97.
-
(2013)
BJU Int
, vol.112
, pp. 288-297
-
-
Gandhi, N.M.1
Morales, A.2
Lamm, D.L.3
-
21
-
-
0023102588
-
A prospective randomized trial of maintenance versus nonmaintenance intravesical bacillus Calmette-Guerin therapy of superficial bladder cancer
-
Badalament RA, Herr HW, Wong GY, Gnecco C, Pinsky CM, Whitmore WF Jr, et al. A prospective randomized trial of maintenance versus nonmaintenance intravesical bacillus Calmette-Guerin therapy of superficial bladder cancer. J Clin Oncol 1987;5:441-9.
-
(1987)
J Clin Oncol
, vol.5
, pp. 441-449
-
-
Badalament, R.A.1
Herr, H.W.2
Wong, G.Y.3
Gnecco, C.4
Pinsky, C.M.5
Whitmore, W.F.6
-
22
-
-
0023387530
-
Single course versus maintenance bacillus Calmette-Guerin therapy for superficial bladder tumors: A prospective, randomized trial
-
Hudson MA, Ratliff TL, Gillen DP, Haaff EO, Dresner SM, Catalona WJ. Single course versus maintenance bacillus Calmette-Guerin therapy for superficial bladder tumors: a prospective, randomized trial. J Urol 1987;138:295-8.
-
(1987)
J Urol
, vol.138
, pp. 295-298
-
-
Hudson, M.A.1
Ratliff, T.L.2
Gillen, D.P.3
Haaff, E.O.4
Dresner, S.M.5
Catalona, W.J.6
-
23
-
-
0035047153
-
Control group and maintenance treatment with bacillus Calmette-Guerin for carcinoma in situ and/or high grade bladder tumors
-
Palou J, Laguna P, Millan-Rodríguez F, Hall RR, Salvador-Bayarri J, Vicente-Rodríguez J. Control group and maintenance treatment with bacillus Calmette-Guerin for carcinoma in situ and/or high grade bladder tumors. J Urol 2001;165:1488-91.
-
(2001)
J Urol
, vol.165
, pp. 1488-1491
-
-
Palou, J.1
Laguna, P.2
Millan-Rodríguez, F.3
Hall, R.R.4
Salvador-Bayarri, J.5
Vicente-Rodríguez, J.6
-
24
-
-
0034105381
-
Maintenance bacillus Calmette-Guerin immunotherapy for recurrent TA, T1 and carcinoma in situ transitional cell carcinoma of the bladder: A randomized Southwest Oncology Group Study
-
Lamm DL, Blumenstein BA, Crissman JD, Montie JE, Gottesman JE, Lowe BA, et al. Maintenance bacillus Calmette-Guerin immunotherapy for recurrent TA, T1 and carcinoma in situ transitional cell carcinoma of the bladder: a randomized Southwest Oncology Group Study. J Urol 2000;163:1124-9.
-
(2000)
J Urol
, vol.163
, pp. 1124-1129
-
-
Lamm, D.L.1
Blumenstein, B.A.2
Crissman, J.D.3
Montie, J.E.4
Gottesman, J.E.5
Lowe, B.A.6
-
25
-
-
77949485656
-
Long-term efficacy results of EORTC genito-urinary group randomized phase 3 study 30911 comparing intravesical instillations of epirubicin, bacillus Calmette-Guerin, and bacillus Calmette-Guerin plus isoniazid in patients with intermediate- and high-risk stage Ta T1 urothelial carcinoma of the bladder
-
Sylvester RJ, Brausi MA, Kirkels WJ, Hoeltl W, Calais Da Silva F, Powell PH, et al. Long-term efficacy results of EORTC genito-urinary group randomized phase 3 study 30911 comparing intravesical instillations of epirubicin, bacillus Calmette-Guerin, and bacillus Calmette-Guerin plus isoniazid in patients with intermediate- and high-risk stage Ta T1 urothelial carcinoma of the bladder. Eur Urol 2010;57:766-73.
-
(2010)
Eur Urol
, vol.57
, pp. 766-773
-
-
Sylvester, R.J.1
Brausi, M.A.2
Kirkels, W.J.3
Hoeltl, W.4
Calais Da Silva, F.5
Powell, P.H.6
-
26
-
-
70449530500
-
Bacillus Calmette-Guerin is superior to a combination of epirubicin and interferon-alpha2b in the intravesical treatment of patients with stage T1 urinary bladder cancer. A prospective, randomized, Nordic study
-
Duchek M, Johansson R, Jahnson S, Mestad O, Hellstrom P, Hellsten S, et al. Bacillus Calmette-Guerin is superior to a combination of epirubicin and interferon-alpha2b in the intravesical treatment of patients with stage T1 urinary bladder cancer. A prospective, randomized, Nordic study. Eur Urol 2010;57:25-31.
-
(2010)
Eur Urol
, vol.57
, pp. 25-31
-
-
Duchek, M.1
Johansson, R.2
Jahnson, S.3
Mestad, O.4
Hellstrom, P.5
Hellsten, S.6
-
27
-
-
84928062583
-
Immune checkpoint blockade: A common denominator approach to cancer therapy
-
Topalian SL, Drake CG, Pardoll DM. Immune checkpoint blockade: a common denominator approach to cancer therapy. Cancer Cell 2015;27:450-61.
-
(2015)
Cancer Cell
, vol.27
, pp. 450-461
-
-
Topalian, S.L.1
Drake, C.G.2
Pardoll, D.M.3
-
28
-
-
0028791059
-
Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
-
Waterhouse P, Penninger JM, Timms E, Wakeham A, Shahinian A, Lee KP, et al. Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science 1995;270:985-8.
-
(1995)
Science
, vol.270
, pp. 985-988
-
-
Waterhouse, P.1
Penninger, J.M.2
Timms, E.3
Wakeham, A.4
Shahinian, A.5
Lee, K.P.6
-
29
-
-
0033180181
-
Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
-
Nishimura H, Nose M, Hiai H, Minato N, Honjo T. Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity 1999;11:141-51.
-
(1999)
Immunity
, vol.11
, pp. 141-151
-
-
Nishimura, H.1
Nose, M.2
Hiai, H.3
Minato, N.4
Honjo, T.5
-
30
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
HodiFS, O'DaySJ, McDermottDF, Weber RW, Sosman JA, Haanen JB, etal. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 2010;363:711-23.
-
(2010)
N Engl J Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
-
31
-
-
84936791837
-
Nivolumab versus docetaxel in advanced squamous-cell non-smallcell lung cancer
-
BrahmerJ, Reckamp KL, Baas P, Crino L, EberhardtWE, Poddubskaya E, et al. Nivolumab versus docetaxel in advanced squamous-cell non-smallcell lung cancer. N Engl J Med 2015;373:123-35.
-
(2015)
N Engl J Med
, vol.373
, pp. 123-135
-
-
Brahmer, J.1
Reckamp, K.L.2
Baas, P.3
Crino, L.4
Eberhardt, W.E.5
Poddubskaya, E.6
-
32
-
-
84929361060
-
Survival, durable response, and long-term safety in patients with previously treated advanced renal cell carcinoma receiving nivolumab
-
McDermott DF, Drake CG, Sznol M, Choueiri TK, Powderly JD, Smith DC, et al. Survival, durable response, and long-term safety in patients with previously treated advanced renal cell carcinoma receiving nivolumab. J Clin Oncol 2015;33:2013-20.
-
(2015)
J Clin Oncol
, vol.33
, pp. 2013-2020
-
-
McDermott, D.F.1
Drake, C.G.2
Sznol, M.3
Choueiri, T.K.4
Powderly, J.D.5
Smith, D.C.6
-
33
-
-
84923078390
-
MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer
-
PowlesT, EderJP, Fine GD, Braiteh FS, LoriotY, CruzC, etal. MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer. Nature 2014;515:558-62.
-
(2014)
Nature
, vol.515
, pp. 558-562
-
-
Powles, T.1
Eder, J.P.2
Fine, G.D.3
Braiteh, F.S.4
Loriot, Y.5
Cruz, C.6
-
34
-
-
0029947568
-
Enhancement of antitumor immunity by CTLA-4 blockade
-
Leach DR, Krummel MF, Allison JP. Enhancement of antitumor immunity by CTLA-4 blockade. Science 1996;271:1734-6.
-
(1996)
Science
, vol.271
, pp. 1734-1736
-
-
Leach, D.R.1
Krummel, M.F.2
Allison, J.P.3
-
35
-
-
0028675006
-
Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors
-
Linsley PS, Greene J A L, Brady W, Bajorath J, Ledbetter JA, Peach R. Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors. Immunity 1994;1:793-801.
-
(1994)
Immunity
, vol.1
, pp. 793-801
-
-
Linsley, P.S.1
Greene, J.A.L.2
Brady, W.3
Bajorath, J.4
Ledbetter, J.A.5
Peach, R.6
-
36
-
-
28244492012
-
Analysis of the cellular mechanism of antitumor responses and autoimmunity in patients treated with CTLA-4 blockade
-
Maker AV, Attia P, Rosenberg SA. Analysis of the cellular mechanism of antitumor responses and autoimmunity in patients treated with CTLA-4 blockade. J Immunol 2005;175:7746-54.
-
(2005)
J Immunol
, vol.175
, pp. 7746-7754
-
-
Maker, A.V.1
Attia, P.2
Rosenberg, S.A.3
-
37
-
-
0038153907
-
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
-
Phan GQ, Yang JC, Sherry RM, Hwu P, Topalian SL, Schwartzentruber DJ, et al. Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma. Proc Natl Acad Sci U S A 2003;100:8372-7.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 8372-8377
-
-
Phan, G.Q.1
Yang, J.C.2
Sherry, R.M.3
Hwu, P.4
Topalian, S.L.5
Schwartzentruber, D.J.6
-
39
-
-
84884271914
-
Fc-dependent depletion of tumor-infiltrating regulatory T cells codefines the efficacy of anti-CTLA-4 therapy against melanoma
-
Simpson TR, Li F, Montalvo-Ortiz W, Sepulveda MA, Bergerhoff K, Arce F, et al. Fc-dependent depletion of tumor-infiltrating regulatory T cells codefines the efficacy of anti-CTLA-4 therapy against melanoma. J Exp Med 2013;210:1695-710.
-
(2013)
J Exp Med
, vol.210
, pp. 1695-1710
-
-
Simpson, T.R.1
Li, F.2
Montalvo-Ortiz, W.3
Sepulveda, M.A.4
Bergerhoff, K.5
Arce, F.6
-
40
-
-
2542614420
-
Differential expression of CTLA-4 among T cell subsets
-
Jago CB, Yates J, Camara NO, Lechler RI, Lombardi G. Differential expression of CTLA-4 among T cell subsets. Clin Exp Immunol 2004;136:463-71.
-
(2004)
Clin Exp Immunol
, vol.136
, pp. 463-471
-
-
Jago, C.B.1
Yates, J.2
Camara, N.O.3
Lechler, R.I.4
Lombardi, G.5
-
41
-
-
84859416933
-
Regulatory T cells: Mechanisms of differentiation and function
-
Josefowicz SZ, Lu LF, Rudensky AY. Regulatory T cells: mechanisms of differentiation and function. Annu Rev Immunol 2012;30:531-64.
-
(2012)
Annu Rev Immunol
, vol.30
, pp. 531-564
-
-
Josefowicz, S.Z.1
Lu, L.F.2
Rudensky, A.Y.3
-
42
-
-
84873372202
-
Advances in targeting cell surface signalling molecules for immune modulation
-
Yao S, Zhu Y, Chen L. Advances in targeting cell surface signalling molecules for immune modulation. Nat Rev Drug Discov 2013;12:130-46.
-
(2013)
Nat Rev Drug Discov
, vol.12
, pp. 130-146
-
-
Yao, S.1
Zhu, Y.2
Chen, L.3
-
43
-
-
81255138488
-
Ipilimumab: An anti-CTLA-4 antibody for metastatic melanoma
-
Lipson EJ, Drake CG. Ipilimumab: an anti-CTLA-4 antibody for metastatic melanoma. Clin Cancer Res 2011;17:6958-62.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 6958-6962
-
-
Lipson, E.J.1
Drake, C.G.2
-
44
-
-
77952337834
-
Preoperative CTLA-4 blockade: Tolerability and immune monitoringinthe setting of a presurgical clinical trial
-
Carthon BC, Wolchok JD, Yuan J, Kamat A, Ng Tang DS, Sun J, et al. Preoperative CTLA-4 blockade: tolerability and immune monitoringinthe setting of a presurgical clinical trial. Clin Cancer Res 2010;16:2861-71.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 2861-2871
-
-
Carthon, B.C.1
Wolchok, J.D.2
Yuan, J.3
Kamat, A.4
Ng Tang, D.S.5
Sun, J.6
-
45
-
-
84959246122
-
Impact of gemcitabine + cisplatin + ipilimumab on circulating immune cells in patients (pts) with metastatic urothelial cancer (mUC)
-
4586
-
Galsky MD, Hahn NM, Albany C, Fleming MT, Starodub A, Twardowski P, et al. Impact of gemcitabine + cisplatin + ipilimumab on circulating immune cells in patients (pts) with metastatic urothelial cancer (mUC). J Clin Oncol 33, 2015(suppl; abstr 4586).
-
(2015)
J Clin Oncol
, vol.33
-
-
Galsky, M.D.1
Hahn, N.M.2
Albany, C.3
Fleming, M.T.4
Starodub, A.5
Twardowski, P.6
-
46
-
-
84864052441
-
Management of immune-related adverse events and kinetics of response with ipilimumab
-
Weber JS, Kahler KC, Hauschild A. Management of immune-related adverse events and kinetics of response with ipilimumab. J Clin Oncol 2012;30:2691-7.
-
(2012)
J Clin Oncol
, vol.30
, pp. 2691-2697
-
-
Weber, J.S.1
Kahler, K.C.2
Hauschild, A.3
-
47
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 2012;12:252-64.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 252-264
-
-
Pardoll, D.M.1
-
48
-
-
84937837169
-
Molecular and cellular insights into T cell exhaustion
-
Wherry EJ, Kurachi M. Molecular and cellular insights into T cell exhaustion. Nat Rev Immunol 2015;15:486-99.
-
(2015)
Nat Rev Immunol
, vol.15
, pp. 486-499
-
-
Wherry, E.J.1
Kurachi, M.2
-
49
-
-
84936147067
-
Combined nivolumab and ipilimumab or monotherapy in untreated melanoma
-
Larkin J, Chiarion-Sileni V, Gonzalez R, Grob JJ, Cowey CL, Lao CD, et al. Combined nivolumab and ipilimumab or monotherapy in untreated melanoma. N Engl J Med 2015;373:23-34.
-
(2015)
N Engl J Med
, vol.373
, pp. 23-34
-
-
Larkin, J.1
Chiarion-Sileni, V.2
Gonzalez, R.3
Grob, J.J.4
Cowey, C.L.5
Lao, C.D.6
-
50
-
-
84929481482
-
Nivolumab and ipilimumab versus ipilimumab in untreated melanoma
-
Postow MA, Chesney J, Pavlick AC, Robert C, Grossmann K, McDermott D, et al. Nivolumab and ipilimumab versus ipilimumab in untreated melanoma. N Engl J Med 2015;372:2006-17.
-
(2015)
N Engl J Med
, vol.372
, pp. 2006-2017
-
-
Postow, M.A.1
Chesney, J.2
Pavlick, A.C.3
Robert, C.4
Grossmann, K.5
McDermott, D.6
-
51
-
-
34248586083
-
Overexpression of B7-H1 (PD-L1) significantly associateswith tumor grade and postoperative prognosis in human urothelial cancers
-
Nakanishi J, Wada Y, Matsumoto K, Azuma M, Kikuchi K, Ueda S. Overexpression of B7-H1 (PD-L1) significantly associateswith tumor grade and postoperative prognosis in human urothelial cancers. Cancer Immunol Immunother 2007;56:1173-82.
-
(2007)
Cancer Immunol Immunother
, vol.56
, pp. 1173-1182
-
-
Nakanishi, J.1
Wada, Y.2
Matsumoto, K.3
Azuma, M.4
Kikuchi, K.5
Ueda, S.6
-
52
-
-
34247113727
-
PD-L1 (B7-H1) expression by urothelial carcinoma of the bladder and BCG-induced granulomata: Associations with localized stage progression
-
Inman BA, Sebo TJ, Frigola X, Dong H, Bergstralh EJ, Frank I, et al. PD-L1 (B7-H1) expression by urothelial carcinoma of the bladder and BCG-induced granulomata: associations with localized stage progression. Cancer 2007;109:1499-505.
-
(2007)
Cancer
, vol.109
, pp. 1499-1505
-
-
Inman, B.A.1
Sebo, T.J.2
Frigola, X.3
Dong, H.4
Bergstralh, E.J.5
Frank, I.6
-
53
-
-
51049096135
-
T-cell coregulatory molecule expression in urothelial cell carcinoma: Clinicopathologic correlations and association with survival
-
Boorjian SA, Sheinin Y, Crispen PL, Farmer SA, Lohse CM, Kuntz SM, et al. T-cell coregulatory molecule expression in urothelial cell carcinoma: clinicopathologic correlations and association with survival. Clin Cancer Res 2008;14:4800-8.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 4800-4808
-
-
Boorjian, S.A.1
Sheinin, Y.2
Crispen, P.L.3
Farmer, S.A.4
Lohse, C.M.5
Kuntz, S.M.6
-
54
-
-
84892544676
-
Association of T-cell co-regulatory protein expression with clinical outcomes following radical cystectomy for urothelial carcinoma of the bladder
-
Xylinas E, Robinson BD, Kluth LA, Volkmer BG, Hautmann R, Kufer R, et al. Association of T-cell co-regulatory protein expression with clinical outcomes following radical cystectomy for urothelial carcinoma of the bladder. Eur J Surg Oncol 2014;40:121-7.
-
(2014)
Eur J Surg Oncol
, vol.40
, pp. 121-127
-
-
Xylinas, E.1
Robinson, B.D.2
Kluth, L.A.3
Volkmer, B.G.4
Hautmann, R.5
Kufer, R.6
-
55
-
-
84920956735
-
Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
-
Herbst RS, Soria J-CC, Kowanetz M, Fine GD, Hamid O, Gordon MS, et al. Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. Nature 2014;515:563-7.
-
(2014)
Nature
, vol.515
, pp. 563-567
-
-
Herbst, R.S.1
Soria, J.-C.C.2
Kowanetz, M.3
Fine, G.D.4
Hamid, O.5
Gordon, M.S.6
-
56
-
-
84947267135
-
Pembrolizumab (MK-3475) for advanced urothelial cancer: Updated results and biomarker analysis from KEYNOTE-012
-
4502
-
Plimack ER, Bellmunt J, Gupta S, Berger R, Montgomery RB, Heath K, et al. Pembrolizumab (MK-3475) for advanced urothelial cancer: updated results and biomarker analysis from KEYNOTE-012. J Clin Oncol 33, 2015(suppl; abstr 4502).
-
(2015)
J Clin Oncol
, vol.33
-
-
Plimack, E.R.1
Bellmunt, J.2
Gupta, S.3
Berger, R.4
Montgomery, R.B.5
Heath, K.6
-
57
-
-
84964391715
-
Patterns of chemotherapy and survival in elderly patients with advanced bladder cancer: A large Medicare database study
-
4551
-
Chen GJ, Galsky MD, Latini DM, Sonpavde G. Patterns of chemotherapy and survival in elderly patients with advanced bladder cancer: a large Medicare database study. J Clin Oncol 31, 2013(suppl; abstr 4551).
-
(2013)
J Clin Oncol
, vol.31
-
-
Chen, G.J.1
Galsky, M.D.2
Latini, D.M.3
Sonpavde, G.4
-
58
-
-
84938329177
-
PD-L1 and survival in solid tumors: A meta-analysis
-
Wu P, Wu D, Li L, Chai Y, Huang J. PD-L1 and survival in solid tumors: a meta-analysis. PLoS One 2015;10:e0131403.
-
(2015)
PLoS One
, vol.10
, pp. e0131403
-
-
Wu, P.1
Wu, D.2
Li, L.3
Chai, Y.4
Huang, J.5
-
59
-
-
84936953099
-
Melanoma-intrinsic beta-catenin signalling prevents anti-tumour immunity
-
Spranger S, BaoR, Gajewski TF. Melanoma-intrinsic beta-catenin signalling prevents anti-tumour immunity. Nature 2015;523:231-5.
-
(2015)
Nature
, vol.523
, pp. 231-235
-
-
Spranger, S.1
Bao, R.2
Gajewski, T.F.3
-
60
-
-
84898001946
-
B7-H3-mediated tumor immunology: Friend or foe?
-
Wang L, Kang FB, Shan BE. B7-H3-mediated tumor immunology: friend or foe? Int J Cancer 2014;134:2764-71.
-
(2014)
Int J Cancer
, vol.134
, pp. 2764-2771
-
-
Wang, L.1
Kang, F.B.2
Shan, B.E.3
-
61
-
-
5844252552
-
B7-H3: A costimulatory molecule for T cell activation and IFN-gamma production
-
Chapoval AI, Ni J, Lau JS, Wilcox RA, Flies DB, Liu D, et al. B7-H3: a costimulatory molecule for T cell activation and IFN-gamma production. Nat Immunol 2001;2:269-74.
-
(2001)
Nat Immunol
, vol.2
, pp. 269-274
-
-
Chapoval, A.I.1
Ni, J.2
Lau, J.S.3
Wilcox, R.A.4
Flies, D.B.5
Liu, D.6
-
62
-
-
34548046956
-
B7-H3 ligand expression by prostate cancer: A novel marker of prognosis and potential target for therapy
-
Roth TJ, Sheinin Y, Lohse CM, Kuntz SM, Frigola X, Inman BA, et al. B7-H3 ligand expression by prostate cancer: a novel marker of prognosis and potential target for therapy. Cancer Res 2007;67:7893-900.
-
(2007)
Cancer Res
, vol.67
, pp. 7893-7900
-
-
Roth, T.J.1
Sheinin, Y.2
Lohse, C.M.3
Kuntz, S.M.4
Frigola, X.5
Inman, B.A.6
-
63
-
-
84863928141
-
Development of an Fc-enhanced anti-B7-H3 monoclonal antibody with potent antitumor activity
-
Loo D, Alderson RF, Chen FZ, Huang L, Zhang W, Gorlatov S, et al. Development of an Fc-enhanced anti-B7-H3 monoclonal antibody with potent antitumor activity. Clin Cancer Res 2012;18:3834-45.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 3834-3845
-
-
Loo, D.1
Alderson, R.F.2
Chen, F.Z.3
Huang, L.4
Zhang, W.5
Gorlatov, S.6
-
64
-
-
84890980389
-
Breathing new life into immunotherapy: Review of melanoma, lung and kidney cancer
-
Drake CG, Lipson EJ, Brahmer JR. Breathing new life into immunotherapy: review of melanoma, lung and kidney cancer. Nat Rev Clin Oncol 2014;11:24-37.
-
(2014)
Nat Rev Clin Oncol
, vol.11
, pp. 24-37
-
-
Drake, C.G.1
Lipson, E.J.2
Brahmer, J.R.3
-
65
-
-
85047692172
-
Therapeutic vaccines for cancer: An overview of clinical trials
-
Melero I, Gaudernack G, Gerritsen W, Huber C, Parmiani G, Scholl S, et al. Therapeutic vaccines for cancer: an overview of clinical trials. Nat Rev Clin Oncol 2014;11:509-24.
-
(2014)
Nat Rev Clin Oncol
, vol.11
, pp. 509-524
-
-
Melero, I.1
Gaudernack, G.2
Gerritsen, W.3
Huber, C.4
Parmiani, G.5
Scholl, S.6
-
66
-
-
0037036369
-
The endoplasmic reticulum-resident heat shock protein Gp96 activates dendritic cells via the Toll-like receptor 2/4 pathway
-
Vabulas RM, Braedel S, Hilf N, Singh-Jasuja H, Herter S, Ahmad-Nejad P, et al. The endoplasmic reticulum-resident heat shock protein Gp96 activates dendritic cells via the Toll-like receptor 2/4 pathway. J Biol Chem 2002;277:20847-53.
-
(2002)
J Biol Chem
, vol.277
, pp. 20847-20853
-
-
Vabulas, R.M.1
Braedel, S.2
Hilf, N.3
Singh-Jasuja, H.4
Herter, S.5
Ahmad-Nejad, P.6
-
67
-
-
84891485779
-
CD8 T cell response in a phase I study of therapeutic vaccination of advanced NSCLC with allogeneic tumor cells secreting endoplasmic reticulum-chaperone gp96-Ig-peptide complexes
-
Raez L, Walker G, Baldie P, Fisher E, Gomez J, Tolba K, et al. CD8 T cell response in a phase I study of therapeutic vaccination of advanced NSCLC with allogeneic tumor cells secreting endoplasmic reticulum-chaperone gp96-Ig-peptide complexes. Adv Lung Cancer 2013;2:9-18.
-
(2013)
Adv Lung Cancer
, vol.2
, pp. 9-18
-
-
Raez, L.1
Walker, G.2
Baldie, P.3
Fisher, E.4
Gomez, J.5
Tolba, K.6
-
68
-
-
84858780815
-
Cancer immunotherapy via dendritic cells
-
Palucka K, Banchereau J. Cancer immunotherapy via dendritic cells. Nat Rev Cancer 2012;12:265-77.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 265-277
-
-
Palucka, K.1
Banchereau, J.2
-
69
-
-
70349456786
-
A phase I trial of immunotherapy with lapuleucel-T (APC8024) in patients with refractory metastatic tumors that express HER-2/neu
-
Peethambaram PP, Melisko ME, Rinn KJ, Alberts SR, Provost NM, Jones LA, et al. A phase I trial of immunotherapy with lapuleucel-T (APC8024) in patients with refractory metastatic tumors that express HER-2/neu. Clin Cancer Res 2009;15:5937-44.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5937-5944
-
-
Peethambaram, P.P.1
Melisko, M.E.2
Rinn, K.J.3
Alberts, S.R.4
Provost, N.M.5
Jones, L.A.6
-
70
-
-
80054866734
-
Science gone translational: The OX40 agonist story
-
Weinberg AD, Morris NP, Kovacsovics-Bankowski M, Urba WJ, Curti BD. Science gone translational: the OX40 agonist story. Immunol Rev 2011;244:218-31.
-
(2011)
Immunol Rev
, vol.244
, pp. 218-231
-
-
Weinberg, A.D.1
Morris, N.P.2
Kovacsovics-Bankowski, M.3
Urba, W.J.4
Curti, B.D.5
-
71
-
-
17644389199
-
TNF/TNFR family members in costimulationof T cell responses
-
Watts TH. TNF/TNFR family members in costimulationof T cell responses. Annu Rev Immunol 2005;23:23-68.
-
(2005)
Annu Rev Immunol
, vol.23
, pp. 23-68
-
-
Watts, T.H.1
-
72
-
-
34948883517
-
OX40 costimulation turns off Foxp3+ Tregs
-
Vu MD, Xiao X, Gao W, Degauque N, Chen M, Kroemer A, et al. OX40 costimulation turns off Foxp3+ Tregs. Blood 2007;110:2501-10.
-
(2007)
Blood
, vol.110
, pp. 2501-2510
-
-
Vu, M.D.1
Xiao, X.2
Gao, W.3
Degauque, N.4
Chen, M.5
Kroemer, A.6
-
73
-
-
84891275907
-
OX40 is a potent immune-stimulating target in late-stage cancer patients
-
Curti BD, Kovacsovics-Bankowski M, Morris N, Walker E, Chisholm L, Floyd K, et al. OX40 is a potent immune-stimulating target in late-stage cancer patients. Cancer Res 2013;73:7189-98.
-
(2013)
Cancer Res
, vol.73
, pp. 7189-7198
-
-
Curti, B.D.1
Kovacsovics-Bankowski, M.2
Morris, N.3
Walker, E.4
Chisholm, L.5
Floyd, K.6
-
74
-
-
62549160588
-
First-in-class, first-in-human phase I results of targeted agents: Highlights of the 2008 American Society of Clinical Oncology Meeting
-
Molckovsky A, Siu LL. First-in-class, first-in-human phase I results of targeted agents: highlights of the 2008 American Society of Clinical Oncology Meeting. J Hematol Oncol 2008;1:20.
-
(2008)
J Hematol Oncol
, vol.1
, pp. 20
-
-
Molckovsky, A.1
Siu, L.L.2
-
75
-
-
78449237499
-
Clinical experiences with anti-CD137 and anti-PD1 therapeutic antibodies
-
Ascierto PA, Simeone E, Sznol M, Fu YX, Melero I. Clinical experiences with anti-CD137 and anti-PD1 therapeutic antibodies. Semin Oncol 2010;37:508-16.
-
(2010)
Semin Oncol
, vol.37
, pp. 508-516
-
-
Ascierto, P.A.1
Simeone, E.2
Sznol, M.3
Fu, Y.X.4
Melero, I.5
-
76
-
-
84875463042
-
Molecular mechanisms of T cell co-stimulation and coinhibition
-
Chen L, Flies DB. Molecular mechanisms of T cell co-stimulation and coinhibition. Nat Rev Immunol 2013;13:227-42.
-
(2013)
Nat Rev Immunol
, vol.13
, pp. 227-242
-
-
Chen, L.1
Flies, D.B.2
-
77
-
-
0032984347
-
Conversion of tumor-specific CD4+ T-cell tolerance to T-cell priming through in vivo ligation of CD40
-
Sotomayor EM, Borrello I, Tubb E, Rattis FM, Bien H, Lu Z, et al. Conversion of tumor-specific CD4+ T-cell tolerance to T-cell priming through in vivo ligation of CD40. Nat Med 1999;5:780-7.
-
(1999)
Nat Med
, vol.5
, pp. 780-787
-
-
Sotomayor, E.M.1
Borrello, I.2
Tubb, E.3
Rattis, F.M.4
Bien, H.5
Lu, Z.6
-
78
-
-
33947506186
-
Clinical activity and immune modulation in cancer patients treated with CP-870, 893, a novel CD40 agonist monoclonal antibody
-
Vonderheide RH, Flaherty KT, Khalil M, Stumacher MS, Bajor DL, Hutnick NA, et al. Clinical activity and immune modulation in cancer patients treated with CP-870, 893, a novel CD40 agonist monoclonal antibody. J Clin Oncol 2007;25:876-83.
-
(2007)
J Clin Oncol
, vol.25
, pp. 876-883
-
-
Vonderheide, R.H.1
Flaherty, K.T.2
Khalil, M.3
Stumacher, M.S.4
Bajor, D.L.5
Hutnick, N.A.6
-
80
-
-
84899473274
-
The predominance of M2-polarized macrophages in the stroma of low-hypoxic bladder tumors is associated with BCG immunotherapy failure
-
Lima L, Oliveira D, Tavares A, Amaro T, Cruz R, Oliveira MJ, et al. The predominance of M2-polarized macrophages in the stroma of low-hypoxic bladder tumors is associated with BCG immunotherapy failure. Urol Oncol 2014;32:449-57.
-
(2014)
Urol Oncol
, vol.32
, pp. 449-457
-
-
Lima, L.1
Oliveira, D.2
Tavares, A.3
Amaro, T.4
Cruz, R.5
Oliveira, M.J.6
-
81
-
-
84866784798
-
Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy
-
DeNardo DG, Brennan DJ, Rexhepaj E, Ruffell B, Shiao SL, Madden SF, et al. Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy. Cancer Discov 2011;1:54-67.
-
(2011)
Cancer Discov
, vol.1
, pp. 54-67
-
-
DeNardo, D.G.1
Brennan, D.J.2
Rexhepaj, E.3
Ruffell, B.4
Shiao, S.L.5
Madden, S.F.6
-
82
-
-
5044220930
-
IDO expression by dendritic cells: Tolerance and tryptophan catabolism
-
Mellor AL, Munn DH. IDO expression by dendritic cells: tolerance and tryptophan catabolism. Nat Rev Immunol 2004;4:762-74.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 762-774
-
-
Mellor, A.L.1
Munn, D.H.2
-
83
-
-
84899921598
-
Indoleamine 2, 3-dioxygenase 1 (IDO1) is up-regulated in thyroid carcinoma and drives the development of an immunosuppressant tumor microenvironment
-
Moretti S, Menicali E, Voce P, Morelli S, Cantarelli S, Sponziello M, et al. Indoleamine 2, 3-dioxygenase 1 (IDO1) is up-regulated in thyroid carcinoma and drives the development of an immunosuppressant tumor microenvironment. J Clin Endocrinol Metab 2014;99:E832-40.
-
(2014)
J Clin Endocrinol Metab
, vol.99
, pp. E832-E840
-
-
Moretti, S.1
Menicali, E.2
Voce, P.3
Morelli, S.4
Cantarelli, S.5
Sponziello, M.6
-
84
-
-
84860852600
-
Blocking IDO activity to enhance anti-tumor immunity
-
Munn DH. Blocking IDO activity to enhance anti-tumor immunity. Front Biosci 2012;4:734-45.
-
(2012)
Front Biosci
, vol.4
, pp. 734-745
-
-
Munn, D.H.1
-
85
-
-
84939150439
-
Expanded cohort results from CheckMate 016: A phase I study of nivolumab in combination with ipilimumab in metastatic renal cell carcinoma (mRCC)
-
4516
-
Hammers HJ, Plimack ER, Infante JR, Rini BI, McDermott DF, Ernstoff M, et al. Expanded cohort results from CheckMate 016: A phase I study of nivolumab in combination with ipilimumab in metastatic renal cell carcinoma (mRCC). J Clin Oncol 33, 2015(suppl; abstr 4516).
-
(2015)
J Clin Oncol
, vol.33
-
-
Hammers, H.J.1
Plimack, E.R.2
Infante, J.R.3
Rini, B.I.4
McDermott, D.F.5
Ernstoff, M.6
-
86
-
-
84933586864
-
Talimogene laherparepvec improves durable response rate in patients with advanced melanoma
-
Andtbacka RH, Kaufman HL, Collichio F, Amatruda T, Senzer N, Chesney J, et al. Talimogene laherparepvec improves durable response rate in patients with advanced melanoma. J Clin Oncol 2015;33:2780-8.
-
(2015)
J Clin Oncol
, vol.33
, pp. 2780-2788
-
-
Andtbacka, R.H.1
Kaufman, H.L.2
Collichio, F.3
Amatruda, T.4
Senzer, N.5
Chesney, J.6
-
87
-
-
84964394951
-
Randomized phase II trial of intravesical adenoviral mediated interferonalpha gene therapy with the excipient Syn3 (Rad-Ifn Alpha/Syn3) in patients with Bcg refractory or relapsing high grade (Hg) non muscle invasive bladder cancer (NMIBC) [abstract]
-
PD17-06 2015 May 15-19; New Orleans, LA. Linthicum MD: AUA
-
Canter D, Boorjian S, Ogan K, Shore N, Bivalacqua T, Bochner B, et al. Randomized phase II trial of intravesical adenoviral mediated interferonalpha gene therapy with the excipient Syn3 (Rad-Ifn Alpha/Syn3) in patients with Bcg refractory or relapsing high grade (Hg) non muscle invasive bladder cancer (NMIBC) [abstract]. In: Proceedings of the 2015 American Urological Association Annual Meeting; 2015 May 15-19; New Orleans, LA. Linthicum (MD): AUA; 2015. Abstract nr PD17-06.
-
(2015)
Proceedings of the 2015 American Urological Association Annual Meeting
-
-
Canter, D.1
Boorjian, S.2
Ogan, K.3
Shore, N.4
Bivalacqua, T.5
Bochner, B.6
|