Infiltration of plasma rich in growth factors enhances in vivo angiogenesis and improves reperfusion and tissue remodeling after severe hind limb ischemia

Journal of Controlled Release

Volumn 202, Issue , 2015, Pages 31-39

  Anitua, Eduardo ^a   Pelacho, Beatriz ^b   Prado, Roberto ^c   Aguirre, José Javier ^c   Sánchez, Mikel ^d   Padilla, Sabino ^a,c   Aranguren, Xabier L ^b   Abizanda, Gloria ^b   Collantes, María ^e   Hernandez, Milagros ^e   Perez Ruiz, Ana ^b   Peñuelas, Ivan ^e   Orive, Gorka ^a   Prosper, Felipe ^b,e  

^a Foundation Eduardo Anitua   (Spain)

^b UNIVERSITY OF NAVARRA   (Spain)

^c Biotechnology Institute BTI   (Spain)

^d Hospital San Jose   (Spain)

^e UNIVERSITY CLINIC OF NAVARRA   (Spain)

Author keywords

Angiogenesis; Controlled release; Growth factors; Myogenesis; Platelet rich plasma

Indexed keywords

BIOACTIVITY; CELLS; ENDOTHELIAL CELLS; MAMMALS; MUSCLE; PLASMA (HUMAN); PLATELETS; TISSUE;

ANGIOGENESIS; CONTROLLED RELEASE; GROWTH FACTOR; MYOGENESIS; PLATELET RICH PLASMA;

TISSUE REGENERATION;

DRUG ADMINISTRATION; GROWTH FACTOR; MATRIGEL; PLASMA RICH IN GROWTH FACTOR; SIGNAL PEPTIDE; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ASSAY; BAGG ALBINO MOUSE; CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFECTS; DRUG THERAPY; ENDOTHELIUM CELL; FIBROSIS; HINDLIMB; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; INCUBATION TEMPERATURE; ISCHEMIA; LIMB ISCHEMIA; MALE; MOUSE; MUSCLE CELL; MUSCLE DEVELOPMENT; MUSCLE REGENERATION; MYOBLAST; NONHUMAN; PATHOLOGY; PHYSIOLOGY; PLASMA; PRIORITY JOURNAL; REGENERATION; REPERFUSION; SKELETAL MUSCLE; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULARIZATION;

ADMINISTRATION AND DOSAGE; ANIMALS; BLOOD SUPPLY; CELL PROLIFERATION; CELLS, CULTURED; DRUG EFFECTS; DRUG THERAPY; FIBROSIS; HINDLIMB; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; ISCHEMIA; MALE; MICE, INBRED BALB C; MUSCLE, SKELETAL; MYOBLASTS; NEOVASCULARIZATION, PHYSIOLOGIC; PATHOLOGY; PHYSIOLOGY; PLASMA; REGENERATION; REPERFUSION;

EID: 84964311256     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.01.029     Document Type: Article

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