Intranasal Delivery of Plasma and Platelet Growth Factors Using PRGF-Endoret System Enhances Neurogenesis in a Mouse Model of Alzheimer's Disease

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Anitua, Eduardo ^a   Pascual, Consuelo ^b,c   Pérez Gonzalez, Rocio ^b,c   Antequera, Desiree ^b,c   Padilla, Sabino ^a   Orive, Gorka ^a,d,e   Carro, Eva ^b,c  

^a Foundation Eduardo Anitua   (Spain)

^b Instituto de Investigacion Hospital 12 de Octubre ^*  (Spain)

^c CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

^d UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^e BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; GROWTH FACTOR; MORPHOGEN; NEUROPROTECTIVE AGENT; NEUROTROPIC AGENT; PLASMA RICH IN GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR; PRESENILIN 1; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL PROLIFERATION; CELL SURVIVAL; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DISEASE MODEL; DRUG DELIVERY SYSTEM; EMBRYO; HIPPOCAMPUS; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; MOUSE; NERVE CELL DEGENERATION; NERVE DEGENERATION; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NEUROPROTECTION; NEUROTROPISM; NONHUMAN; RAT;

ADULT; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FEMALE; HIPPOCAMPUS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MIDDLE AGED; NEUROGENESIS; PLASMA; PRESENILIN-1; RATS;

EID: 84884405373     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0073118     Document Type: Article

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