Effects and molecular mechanisms of the antidiabetic fraction of Acorus calamus L. on GLP-1 expression and secretion in vivo and in vitro

Journal of Ethnopharmacology

Volumn 166, Issue , 2015, Pages 168-175

  Liu, Yun Xi ^a   Si, Mei Mei ^a   Lu, Wei ^b   Zhang, Li Xia ^b   Zhou, Chang Xin ^b   Deng, Shu Li ^b   Wu, Hao Shu ^a,b  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

Acorus calamus L.; Antidiabetic mechanism; Ethylacetatefraction; GLP 1

Indexed keywords

ANTIDIABETIC AGENT; BETA CATENIN; CYCLIN D1; ETHYL ACETATE FRACTION OF ACORUS CALAMUS; GLUCAGON LIKE PEPTIDE 1; GLUCOSE BLOOD LEVEL; INSULIN; PHARMACOLOGY; PROGLUCAGON; PROPROTEIN CONVERTASE 1; STREPTOZOCIN; UNCLASSIFIED DRUG;

ACORUS; ACORUS CALAMUS; ANIMAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDIABETIC ACTIVITY; ARTICLE; C57BL MOUSE; CHEMISTRY; CONTROLLED STUDY; CULTURE MEDIUM; DIABETES MELLITUS, EXPERIMENTAL; DIET INDUCED OBESITY; DRUG EFFECTS; DRUG MECHANISM; DRUG THERAPY; ENDOCRINE FUNCTION; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; IN VITRO STUDY; IN VIVO STUDY; INSULIN BLOOD LEVEL; INSULIN RELEASE; L CELL LINE; MALE; METABOLISM; MOUSE; MOUSE MUTANT; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET BETA CELL; PROCEDURES; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN SECRETION; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; WNT SIGNALING PATHWAY;

ACORUS; ANIMALS; BETA CATENIN; BLOOD GLUCOSE; CHEMISTRY; DIABETES MELLITUS, EXPERIMENTAL; DRUG EFFECTS; DRUG THERAPY; GLUCAGON-LIKE PEPTIDE 1; GLUCOSE TOLERANCE TEST; HYPOGLYCEMIC AGENTS; INSULIN; MALE; METABOLISM; METHODS; MICE; MICE, INBRED C57BL; MICE, OBESE; PHARMACOLOGY; PROGLUCAGON; PROTEIN PROCESSING, POST-TRANSLATIONAL; WNT SIGNALING PATHWAY;

ACORUS CALAMUS; MUS;

EID: 84964297922     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2015.03.014     Document Type: Article

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