메뉴 건너뛰기




Volumn 24, Issue 3, 2016, Pages 556-563

Thymol reduces oxidative stress, aortic intimal thickening, and inflammation-related gene expression in hyperlipidemic rabbits

Author keywords

antioxidant; atherosclerosis; inflammatory markers; oxidative stress; thymol

Indexed keywords

ANTIOXIDANT; BIOLOGICAL MARKER; GELATINASE B; INTERLEUKIN 1BETA; INTERLEUKIN 6; LYMPHOTOXIN; MONOCYTE CHEMOTACTIC PROTEIN 1; THYMOL; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

EID: 84964277229     PISSN: 10219498     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jfda.2016.02.004     Document Type: Article
Times cited : (60)

References (44)
  • 1
    • 0041695231 scopus 로고    scopus 로고
    • Emerging risk factors for atherosclerotic vascular disease: a critical review of the evidence
    • [1] Hackam, D.G., Anand, S.S., Emerging risk factors for atherosclerotic vascular disease: a critical review of the evidence. JAMA 290 (2003), 932–940.
    • (2003) JAMA , vol.290 , pp. 932-940
    • Hackam, D.G.1    Anand, S.S.2
  • 3
  • 5
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • [5] Libby, P., Inflammation in atherosclerosis. Nature 420 (2002), 868–874.
    • (2002) Nature , vol.420 , pp. 868-874
    • Libby, P.1
  • 6
    • 79958032424 scopus 로고    scopus 로고
    • Inflammation and the development of atherosclerosis
    • [6] Mizuno, Y., Jacob, R.F., Mason, R.P., Inflammation and the development of atherosclerosis. J Atheroscler Thromb 18 (2011), 351–358.
    • (2011) J Atheroscler Thromb , vol.18 , pp. 351-358
    • Mizuno, Y.1    Jacob, R.F.2    Mason, R.P.3
  • 7
    • 0035800880 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibition after myocardial infarction: a new approach to prevent heart failure?
    • [7] Creemers, E.E., Cleutjens, J.P., Smits, J.F., Daemen, M.J., Matrix metalloproteinase inhibition after myocardial infarction: a new approach to prevent heart failure?. Circ Res 89 (2001), 201–210.
    • (2001) Circ Res , vol.89 , pp. 201-210
    • Creemers, E.E.1    Cleutjens, J.P.2    Smits, J.F.3    Daemen, M.J.4
  • 8
    • 76049125185 scopus 로고    scopus 로고
    • Matrix metalloproteinases and peripheral arterial disease
    • [8] Busti, C., Falcinelli, E., Momi, S., Gresele, P., Matrix metalloproteinases and peripheral arterial disease. Intern Emerg Med 5 (2010), 13–25.
    • (2010) Intern Emerg Med , vol.5 , pp. 13-25
    • Busti, C.1    Falcinelli, E.2    Momi, S.3    Gresele, P.4
  • 9
    • 0036843534 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 is necessary for the regulation of smooth muscle cell replication and migration after arterial injury
    • [9] Cho, A., Reidy, M.A., Matrix metalloproteinase-9 is necessary for the regulation of smooth muscle cell replication and migration after arterial injury. Circ Res 91 (2002), 845–851.
    • (2002) Circ Res , vol.91 , pp. 845-851
    • Cho, A.1    Reidy, M.A.2
  • 10
    • 0036844555 scopus 로고    scopus 로고
    • Targeted disruption of the matrix metalloproteinase-9 gene impairs smooth muscle cell migration and geometrical arterial remodeling
    • [10] Galis, Z.S., Johnson, C., Godin, D., Magid, R., Shipley, J.M., Senior, R.M., Ivan, E., Targeted disruption of the matrix metalloproteinase-9 gene impairs smooth muscle cell migration and geometrical arterial remodeling. Circ Res 91 (2002), 852–859.
    • (2002) Circ Res , vol.91 , pp. 852-859
    • Galis, Z.S.1    Johnson, C.2    Godin, D.3    Magid, R.4    Shipley, J.M.5    Senior, R.M.6    Ivan, E.7
  • 11
    • 84908520874 scopus 로고    scopus 로고
    • Plants belonging to the genus Thymus as antibacterial agents: from farm to pharmacy
    • [11] Nabavi, S.M., Marchese, A., Izadi, M., Curti, V., Daglia, M., Nabavi, S.F., Plants belonging to the genus Thymus as antibacterial agents: from farm to pharmacy. Food Chem 173 (2015), 339–347.
    • (2015) Food Chem , vol.173 , pp. 339-347
    • Nabavi, S.M.1    Marchese, A.2    Izadi, M.3    Curti, V.4    Daglia, M.5    Nabavi, S.F.6
  • 12
    • 4644372714 scopus 로고    scopus 로고
    • Comprehensive study on vitamin C equivalent antioxidant capacity (VCEAC) of various polyphenolics in scavenging a free radical and its structural relationship
    • [12] Kim, D.O., Lee, C.Y., Comprehensive study on vitamin C equivalent antioxidant capacity (VCEAC) of various polyphenolics in scavenging a free radical and its structural relationship. Crit Rev Food Sci Nutr 44 (2004), 253–273.
    • (2004) Crit Rev Food Sci Nutr , vol.44 , pp. 253-273
    • Kim, D.O.1    Lee, C.Y.2
  • 14
    • 78149447264 scopus 로고    scopus 로고
    • Natural antioxidants: fascinating or mythical biomolecules?
    • [14] Ndhlala, A.R., Moyo, M., Van Staden, J., Natural antioxidants: fascinating or mythical biomolecules?. Molecules 15 (2010), 6905–6930.
    • (2010) Molecules , vol.15 , pp. 6905-6930
    • Ndhlala, A.R.1    Moyo, M.2    Van Staden, J.3
  • 15
    • 84908356276 scopus 로고    scopus 로고
    • Flavonoid compositions and antioxidant activity of calamondin extracts prepared using different solvents
    • [15] Lou, S.N., Hsu, Y.S., Ho, C.T., Flavonoid compositions and antioxidant activity of calamondin extracts prepared using different solvents. J Food Drug Anal 22 (2014), 290–295.
    • (2014) J Food Drug Anal , vol.22 , pp. 290-295
    • Lou, S.N.1    Hsu, Y.S.2    Ho, C.T.3
  • 16
    • 84885647510 scopus 로고    scopus 로고
    • The antioxidant and cytoprotective activity of Ocimum gratissimum extracts against hydrogen peroxide-induced toxicity in human HepG2 cells
    • [16] Chiu, Y.W., Lo, H.J., Huang, H.Y., Chao, P.Y., Hwang, J.M., Huang, P.Y., Huang, S.J., Liu, J.Y., Lai, T.J., The antioxidant and cytoprotective activity of Ocimum gratissimum extracts against hydrogen peroxide-induced toxicity in human HepG2 cells. J Food Drug Anal 21 (2013), 253–260.
    • (2013) J Food Drug Anal , vol.21 , pp. 253-260
    • Chiu, Y.W.1    Lo, H.J.2    Huang, H.Y.3    Chao, P.Y.4    Hwang, J.M.5    Huang, P.Y.6    Huang, S.J.7    Liu, J.Y.8    Lai, T.J.9
  • 17
    • 84908356734 scopus 로고    scopus 로고
    • Effect of extraction solvent on total phenol content, total flavonoid content, and antioxidant activity of Limnophila aromatica
    • [17] Do, Q.D., Angkawijaya, A.E., Tran-Nguyen, P.L., Huynh, L.H., Soetaredjo, F.E., Ismadji, S., Ju, Y.H., Effect of extraction solvent on total phenol content, total flavonoid content, and antioxidant activity of Limnophila aromatica. J Food Drug Anal 22 (2014), 296–302.
    • (2014) J Food Drug Anal , vol.22 , pp. 296-302
    • Do, Q.D.1    Angkawijaya, A.E.2    Tran-Nguyen, P.L.3    Huynh, L.H.4    Soetaredjo, F.E.5    Ismadji, S.6    Ju, Y.H.7
  • 18
    • 84938614403 scopus 로고    scopus 로고
    • Review of ethnobotanical, phytochemical, and pharmacological study of Thymus serpyllum L.
    • [18] Jaric, S., Mitrovic, M., Pavlovic, P., Review of ethnobotanical, phytochemical, and pharmacological study of Thymus serpyllum L. Evid Based Complement Alternat Med, 2015, 2015, 101978.
    • (2015) Evid Based Complement Alternat Med , vol.2015 , pp. 101978
    • Jaric, S.1    Mitrovic, M.2    Pavlovic, P.3
  • 19
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis—an inflammatory disease
    • [19] Ross, R., Atherosclerosis—an inflammatory disease. N Engl J Med 340 (1999), 115–126.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 20
    • 84921319370 scopus 로고    scopus 로고
    • Rabbit models for the study of human atherosclerosis: from pathophysiological mechanisms to translational medicine
    • [20] Fan, J., Kitajima, S., Watanabe, T., Xu, J., Zhang, J., Liu, E., Chen, Y.E., Rabbit models for the study of human atherosclerosis: from pathophysiological mechanisms to translational medicine. Pharmacol Ther 146 (2015), 104–119.
    • (2015) Pharmacol Ther , vol.146 , pp. 104-119
    • Fan, J.1    Kitajima, S.2    Watanabe, T.3    Xu, J.4    Zhang, J.5    Liu, E.6    Chen, Y.E.7
  • 21
    • 0037059573 scopus 로고    scopus 로고
    • Experimental atherosclerosis: a historical overview
    • [21] Moghadasian, M.H., Experimental atherosclerosis: a historical overview. Life Sci 70 (2002), 855–865.
    • (2002) Life Sci , vol.70 , pp. 855-865
    • Moghadasian, M.H.1
  • 22
    • 0027509770 scopus 로고
    • A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates
    • [22] Miller, N.J., Rice-Evans, C., Davies, M.J., Gopinathan, V., Milner, A., A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates. Clin Sci (Lond) 84 (1993), 407–412.
    • (1993) Clin Sci (Lond) , vol.84 , pp. 407-412
    • Miller, N.J.1    Rice-Evans, C.2    Davies, M.J.3    Gopinathan, V.4    Milner, A.5
  • 23
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • [23] Ohkawa, H., Ohishi, N., Yagi, K., Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95 (1979), 351–358.
    • (1979) Anal Biochem , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 24
    • 26844443365 scopus 로고    scopus 로고
    • Reduction of oxidative stress and apoptosis in hyperlipidemic rabbits by ellagic acid
    • [24] Yu, Y.M., Chang, W.C., Wu, C.H., Chiang, S.Y., Reduction of oxidative stress and apoptosis in hyperlipidemic rabbits by ellagic acid. J Nutr Biochem 16 (2005), 675–681.
    • (2005) J Nutr Biochem , vol.16 , pp. 675-681
    • Yu, Y.M.1    Chang, W.C.2    Wu, C.H.3    Chiang, S.Y.4
  • 26
    • 84984572980 scopus 로고    scopus 로고
    • Quantification and genotyping of hepatitis B virus in a single reaction by real-time PCR and melting curve analysis
    • [26] Yeh, S.H., Tsai, C.Y., Kao, J.H., Liu, C.J., Kuo, T.J., Lin, M.W., Huang, W.L., Lu, S.F., Jih, J., Chen, D.S., Chen, P.J., Quantification and genotyping of hepatitis B virus in a single reaction by real-time PCR and melting curve analysis. J Hepatol 41 (2004), 659–666.
    • (2004) J Hepatol , vol.41 , pp. 659-666
    • Yeh, S.H.1    Tsai, C.Y.2    Kao, J.H.3    Liu, C.J.4    Kuo, T.J.5    Lin, M.W.6    Huang, W.L.7    Lu, S.F.8    Jih, J.9    Chen, D.S.10    Chen, P.J.11
  • 27
    • 80054950439 scopus 로고    scopus 로고
    • Antimicrobial, antioxidant, and anti-inflammatory activities of essential oils from five selected herbs
    • [27] Tsai, M.L., Lin, C.C., Lin, W.C., Yang, C.H., Antimicrobial, antioxidant, and anti-inflammatory activities of essential oils from five selected herbs. Biosci Biotechnol Biochem 75 (2011), 1977–1983.
    • (2011) Biosci Biotechnol Biochem , vol.75 , pp. 1977-1983
    • Tsai, M.L.1    Lin, C.C.2    Lin, W.C.3    Yang, C.H.4
  • 28
    • 84864575551 scopus 로고    scopus 로고
    • Comprehensive assessment of antioxidant activity of essential oils
    • [28] Anthony, K.P., Deolu-Sobogun, S.A., Saleh, M.A., Comprehensive assessment of antioxidant activity of essential oils. J Food Sci 77 (2012), C839–C843.
    • (2012) J Food Sci , vol.77 , pp. C839-C843
    • Anthony, K.P.1    Deolu-Sobogun, S.A.2    Saleh, M.A.3
  • 31
    • 48749124593 scopus 로고    scopus 로고
    • The anti-atherosclerotic effect of olive leaf extract is related to suppressed inflammatory response in rabbits with experimental atherosclerosis
    • [31] Wang, L., Geng, C., Jiang, L., Gong, D., Liu, D., Yoshimura, H., Zhong, L., The anti-atherosclerotic effect of olive leaf extract is related to suppressed inflammatory response in rabbits with experimental atherosclerosis. Eur J Nutr 47 (2008), 235–243.
    • (2008) Eur J Nutr , vol.47 , pp. 235-243
    • Wang, L.1    Geng, C.2    Jiang, L.3    Gong, D.4    Liu, D.5    Yoshimura, H.6    Zhong, L.7
  • 33
    • 0027424327 scopus 로고
    • Hepatic expression of genes regulating lipid metabolism in rabbits
    • [33] Rea, T.J., DeMattos, R.B., Pape, M.E., Hepatic expression of genes regulating lipid metabolism in rabbits. J Lipid Res 34 (1993), 1901–1910.
    • (1993) J Lipid Res , vol.34 , pp. 1901-1910
    • Rea, T.J.1    DeMattos, R.B.2    Pape, M.E.3
  • 34
    • 0032546789 scopus 로고    scopus 로고
    • Differential roles of extracellular signal-regulated kinase-1/2 and p38(MAPK) in interleukin-1beta- and tumor necrosis factor-alpha-induced low density lipoprotein receptor expression in HepG2 cells
    • [34] Kumar, A., Middleton, A., Chambers, T.C., Mehta, K.D., Differential roles of extracellular signal-regulated kinase-1/2 and p38(MAPK) in interleukin-1beta- and tumor necrosis factor-alpha-induced low density lipoprotein receptor expression in HepG2 cells. J Biol Chem 273 (1998), 15742–15748.
    • (1998) J Biol Chem , vol.273 , pp. 15742-15748
    • Kumar, A.1    Middleton, A.2    Chambers, T.C.3    Mehta, K.D.4
  • 35
    • 26444588695 scopus 로고    scopus 로고
    • Cardioprotective effects of dietary polyphenols
    • [35] Zern, T.L., Fernandez, M.L., Cardioprotective effects of dietary polyphenols. J Nutr 135 (2005), 2291–2294.
    • (2005) J Nutr , vol.135 , pp. 2291-2294
    • Zern, T.L.1    Fernandez, M.L.2
  • 36
    • 33746567447 scopus 로고    scopus 로고
    • One-month administration of hydroxytyrosol, a phenolic antioxidant present in olive oil, to hyperlipidemic rabbits improves blood lipid profile, antioxidant status and reduces atherosclerosis development
    • [36] González-Santiago, M., Martín-Bautista, E., Carrero, J.J., Fonollá, J., Baró, L., Bartolomé, M.V., Gil-Loyzaga, P., López-Huertas, E., One-month administration of hydroxytyrosol, a phenolic antioxidant present in olive oil, to hyperlipidemic rabbits improves blood lipid profile, antioxidant status and reduces atherosclerosis development. Atherosclerosis 188 (2006), 35–42.
    • (2006) Atherosclerosis , vol.188 , pp. 35-42
    • González-Santiago, M.1    Martín-Bautista, E.2    Carrero, J.J.3    Fonollá, J.4    Baró, L.5    Bartolomé, M.V.6    Gil-Loyzaga, P.7    López-Huertas, E.8
  • 37
    • 0020971452 scopus 로고
    • Acute phase proteins with special reference to C-reactive protein and related proteins (pentaxins) and serum amyloid A protein
    • [37] Pepys, M.B., Baltz, M.L., Acute phase proteins with special reference to C-reactive protein and related proteins (pentaxins) and serum amyloid A protein. Adv Immunol 34 (1983), 141–212.
    • (1983) Adv Immunol , vol.34 , pp. 141-212
    • Pepys, M.B.1    Baltz, M.L.2
  • 38
    • 34248641015 scopus 로고    scopus 로고
    • C-reactive protein and the prediction of cardiovascular events among those at intermediate risk: moving an inflammatory hypothesis toward consensus
    • [38] Ridker, P.M., C-reactive protein and the prediction of cardiovascular events among those at intermediate risk: moving an inflammatory hypothesis toward consensus. J Am Coll Cardiol 49 (2007), 2129–2138.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 2129-2138
    • Ridker, P.M.1
  • 39
    • 0030797134 scopus 로고    scopus 로고
    • Effect of probucol treatment on gene expression of VCAM-1, MCP-1, and M-CSF in the aortic wall of LDL receptor-deficient rabbits during early atherogenesis
    • [39] Fruebis, J., Gonzalez, V., Silvestre, M., Palinski, W., Effect of probucol treatment on gene expression of VCAM-1, MCP-1, and M-CSF in the aortic wall of LDL receptor-deficient rabbits during early atherogenesis. Arterioscler Thromb Vasc Biol 17 (1997), 1289–1302.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 1289-1302
    • Fruebis, J.1    Gonzalez, V.2    Silvestre, M.3    Palinski, W.4
  • 40
    • 0033956625 scopus 로고    scopus 로고
    • The role of MCP-1 in atherosclerosis
    • [40] Harrington, J.R., The role of MCP-1 in atherosclerosis. Stem Cells 18 (2000), 65–66.
    • (2000) Stem Cells , vol.18 , pp. 65-66
    • Harrington, J.R.1
  • 42
    • 61449191579 scopus 로고    scopus 로고
    • Carnosic acid reduces cytokine-induced adhesion molecules expression and monocyte adhesion to endothelial cells
    • [42] Yu, Y.M., Lin, C.H., Chan, H.C., Tsai, H.D., Carnosic acid reduces cytokine-induced adhesion molecules expression and monocyte adhesion to endothelial cells. Eur J Nutr 48 (2009), 101–106.
    • (2009) Eur J Nutr , vol.48 , pp. 101-106
    • Yu, Y.M.1    Lin, C.H.2    Chan, H.C.3    Tsai, H.D.4
  • 43
    • 0031080138 scopus 로고    scopus 로고
    • a pivotal role in asthma and a new target for therapy
    • [43] Barnes, P.J., Adcock, I.M., NF-kappa, B., a pivotal role in asthma and a new target for therapy. Trends Pharmacol Sci 18 (1997), 46–50.
    • (1997) Trends Pharmacol Sci , vol.18 , pp. 46-50
    • Barnes, P.J.1    Adcock, I.M.2    NF-kappa, B.3
  • 44
    • 77955920306 scopus 로고    scopus 로고
    • Chlorogenic acid attenuates adhesion molecules upregulation in IL-1beta-treated endothelial cells
    • [44] Chang, W.C., Chen, C.H., Lee, M.F., Chang, T., Yu, Y.M., Chlorogenic acid attenuates adhesion molecules upregulation in IL-1beta-treated endothelial cells. Eur J Nutr 49 (2010), 267–275.
    • (2010) Eur J Nutr , vol.49 , pp. 267-275
    • Chang, W.C.1    Chen, C.H.2    Lee, M.F.3    Chang, T.4    Yu, Y.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.