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Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 4, 2015, Pages 781-786

6-(Azaindol-2-yl)pyridine-3-sulfonamides as potent and selective inhibitors targeting hepatitis C virus NS4B

(18) Chen, Guangming a Ren, Hongyu a Zhang, Nanjing a Lennox, William a Turpoff, Anthony a Paget, Steven a Li, Chunshi a Almstead, Neil a Njoroge, F George b Gu, Zhengxian a Graci, Jason a Jung, Stephen P a Colacino, Joseph a Lahser, Fred b Zhao, Xin a Weetall, Marla a Nomeir, Amin b Karp, Gary M a

a PTC THERAPEUTICS (United States)

b MERCK RESEARCH LABORATORIES (United States)

Author keywords

6 (Azaindol 2 yl)pyridine 3 sulfonamides; HCV inhibitors; NS4B; Replicon; Structureactivity relationship

Indexed keywords

6 (AZAINDOL 2 YL)PYRIDINE 3 SULFONAMIDE DERIVATIVE; ANTIVIRUS AGENT; RNA; SULFONAMIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CELL ASSAY; CELL CULTURE; DOG; DRUG IDENTIFICATION; DRUG POTENCY; EC50; HAPLORHINI; HEPATITIS C VIRUS; HEPATITIS C VIRUS SUBTYPE 1B; MALE; NONHUMAN; RAT; REPLICON; REPLICON CELL; STRUCTURE ACTIVITY RELATION;

CANIS FAMILIARIS; HEPATITIS C VIRUS; RATTUS;

EID: 84964269940 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2014.12.093 Document Type: Article

Times cited : (14)

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