Endotoxemia Engages the RhoA Kinase Pathway to Impair Cardiac Function By Altering Cytoskeleton, Mitochondrial Fission, and Autophagy

Antioxidants and Redox Signaling

Volumn 24, Issue 10, 2016, Pages 529-542

  Preau, Sebastien ^a,b   Delguste, Florian ^a   Yu, Yichi ^a,c   Remy Jouet, Isabelle ^d   Richard, Vincent ^d   Saulnier, Fabienne ^b   Boulanger, Eric ^a   Neviere, Remi ^a  

^a UNIVERSITÉ DE LILLE   (France)

^b LILLE UNIVERSITY HOSPITAL   (France)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d UNIVERSITY OF ROUEN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

9 BENZOYLOXY 5,11 DIMETHYL 2H,6H PYRIDO[4,3 B]CARBAZOL 1 ONE; CARBAZOLE DERIVATIVE; CATALASE; COFILIN; COPPER ZINC SUPEROXIDE DISMUTASE; DYNAMIN; DYNAMIN RELATED PROTEIN 1; F ACTIN; FASUDIL; GLYCOPROTEIN GP 91; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MALONALDEHYDE; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; MITOCHONDRIAL DIVISION INHIBITOR 1; PROTEIN INHIBITOR; PYRIDINE DERIVATIVE; REACTIVE OXYGEN METABOLITE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; ACTIN DEPOLYMERIZING FACTOR; CALCIUM CHANNEL BLOCKING AGENT; RHO KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOENERGY; CARDITIS; CELL VACUOLE; CONTROLLED STUDY; CYTOSKELETON; CYTOSOL; DRUG POTENCY; EXPERIMENTAL ENDOTOXEMIA; HEART MUSCLE CONTRACTILITY; HEART PROTECTION; HOMEOSTASIS; LYSOSOME; MITOCHONDRIAL RESPIRATION; MITOPHAGY; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN POLYMERIZATION; PROTEIN STABILITY; SEPSIS; ANALOGS AND DERIVATIVES; ANIMAL; AUTOPHAGY; CARDIAC MUSCLE; DRUG EFFECTS; ENDOTOXEMIA; GENE EXPRESSION; GENETICS; HEART; HEART CONTRACTION; MALE; METABOLISM; MITOCHONDRIAL DYNAMICS; MYOCARDITIS; PATHOLOGY; PATHOPHYSIOLOGY; SARCOMERE; SIGNAL TRANSDUCTION; ULTRASTRUCTURE;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ACTIN DEPOLYMERIZING FACTORS; ANIMALS; AUTOPHAGY; CALCIUM CHANNEL BLOCKERS; CYTOSKELETON; ENDOTOXEMIA; GENE EXPRESSION; HEART; LIPOPOLYSACCHARIDES; MALE; MICE; MITOCHONDRIAL DYNAMICS; MYOCARDIAL CONTRACTION; MYOCARDITIS; MYOCARDIUM; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RHO-ASSOCIATED KINASES; SARCOMERES; SIGNAL TRANSDUCTION;

EID: 84964255288     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2015.6421     Document Type: Article

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