Pyridine and pyridinone-based factor XIa inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 4, 2015, Pages 925-930

  Corte, James R ^a   Fang, Tianan ^a   Hangeland, Jon J ^a   Friends, Todd J ^a   Rendina, Alan R ^a   Luettgen, Joseph M ^a   Bozarth, Jeffrey M ^a   Barbera, Frank A ^a   Rossi, Karen A ^a   Wei, Anzhi ^a   Ramamurthy, Vidhyashankar ^a   Morin, Paul E ^a   Seiffert, Dietmar A ^a   Wexler, Ruth R ^a   Quan, Mimi L ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Activated partial thromboplastin time; aPTT; Factor; FXIa; Thrombosis; XIa inhibitors

Indexed keywords

BLOOD CLOTTING FACTOR 11A; IMIDAZOLE; ORGANIC COMPOUND; PYRIDINE; SERINE PROTEINASE INHIBITOR;

ARTICLE; CRYSTAL STRUCTURE; HUMAN; STRUCTURE ACTIVITY RELATION; X RAY;

EID: 84964204520     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2014.12.050     Document Type: Article

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