Impaired coronary metabolic dilation in the metabolic syndrome is linked to mitochondrial dysfunction and mitochondrial DNA damage

Basic Research in Cardiology

Volumn 111, Issue 3, 2016, Pages

  Guarini, Giacinta ^a,c   Kiyooka, Takahiko ^b   Ohanyan, Vahagn ^c   Pung, Yuh Fen ^c,d   Marzilli, Mario ^a   Chen, Yeong Renn ^c   Chen, Chwen Lih ^c   Kang, Patrick T ^c   Hardwick, James P ^c   Kolz, Christopher L ^c   Yin, Liya ^c   Wilson, Glenn L ^e   Shokolenko, Inna ^e   Dobson, James G ^f   Fenton, Richard ^f   Chilian, William M ^c  

^a UNIVERSITY OF PISA   (Italy)

^b TOKAI UNIVERSITY OISO HOSPITAL   (Japan)

^c Northeastern Ohio Medical University   (United States)

^d UNIVERSITY OF NOTTINGHAM MALAYSIA CAMPUS   (Malaysia)

^e UNIVERSITY OF SOUTH ALABAMA   (United States)

^f UNIVERSITY OF MASSACHUSETTS BOSTON   (United States)

Author keywords

Coronary circulation; Coronary microcirculation; Diabetes; Mitochondria; Obesity

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL PRESSURE; ARTICLE; BLOOD CHEMISTRY; CONTRAST ECHOCARDIOGRAPHY; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA DAMAGE; HEART MUSCLE BLOOD FLOW; HEART MUSCLE CELL; HEART MUSCLE METABOLISM; HEART RATE; HEMODYNAMICS; HYPEREMIA; HYPOXEMIA; MALE; METABOLIC SYNDROME X; MITOCHONDRIAL RESPIRATION; NONHUMAN; OBESITY; RAT; ANIMAL; CORONARY BLOOD VESSEL; DISEASE MODEL; DNA FRAGMENTATION; METABOLISM; MITOCHONDRION; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PHYSIOLOGY; VASODILATATION; ZUCKER RAT;

ANIMALS; CORONARY VESSELS; DISEASE MODELS, ANIMAL; DNA DAMAGE; DNA FRAGMENTATION; DNA, MITOCHONDRIAL; METABOLIC SYNDROME X; MITOCHONDRIA; OXIDATIVE STRESS; RATS; RATS, ZUCKER; REACTIVE OXYGEN SPECIES; VASODILATION;

EID: 84964090263     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-016-0547-4     Document Type: Article

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