Molecular Plasticity of the Human Voltage-Dependent Anion Channel Embedded into a Membrane

Structure

Volumn 24, Issue 4, 2016, Pages 585-594

  Ge, Lin ^a   Villinger, Saskia ^b   Mari, Stefania A ^a   Giller, Karin ^b   Griesinger, Christian ^b   Becker, Stefan ^b   Müller, Daniel J ^a   Zweckstetter, Markus ^b,c,d  

^a ETH ZURICH   (Switzerland)

^b MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^c GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^d UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

Author keywords

atomic force microscopy; calcium dependency; conformational variability; human voltage dependent anion channel; integral membrane protein; NMR spectroscopy; single molecule force spectroscopy; structural flexibility

Indexed keywords

CALCIUM ION; MAGNESIUM ION; VOLTAGE DEPENDENT ANION CHANNEL; CALCIUM; VDAC1 PROTEIN, HUMAN; VOLTAGE DEPENDENT ANION CHANNEL 1;

AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; ATOMIC FORCE MICROSCOPY; CONFORMATIONAL TRANSITION; MITOCHONDRION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FUNCTION; CHEMISTRY; HUMAN; KINETICS; METABOLISM; MITOCHONDRIAL MEMBRANE; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE; PROTEIN SECONDARY STRUCTURE; SINGLE MOLECULE IMAGING;

CALCIUM; HUMANS; KINETICS; MITOCHONDRIAL MEMBRANES; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN STRUCTURE, SECONDARY; SINGLE MOLECULE IMAGING; VOLTAGE-DEPENDENT ANION CHANNEL 1;

EID: 84964054932     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2016.02.012     Document Type: Article

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