-
1
-
-
64349105205
-
Identification and importance of brown adipose tissue in adult humans
-
Cypess, A. M., S. Lehman, G. Williams, I. Tal, D. Rodman, A. B. Goldfine, F. C. Kuo, E. L. Palmer, Y. H. Tseng, A. Doria, et al. 2009. Identification and importance of brown adipose tissue in adult humans. N. Engl. J. Med. 360: 1509-1517.
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 1509-1517
-
-
Cypess, A.M.1
Lehman, S.2
Williams, G.3
Tal, I.4
Rodman, D.5
Goldfine, A.B.6
Kuo, F.C.7
Palmer, E.L.8
Tseng, Y.H.9
Doria, A.10
-
2
-
-
64349095231
-
Cold-activated brown adipose tissue in healthy men
-
van Marken Lichtenbelt, W. D., J. W. Vanhommerig, N. M. Smulders, J. M. Drossaerts, G. J. Kemerink, N. D. Bouvy, P. Schrauwen, and G. J. Teule. 2009. Cold-activated brown adipose tissue in healthy men. N. Engl. J. Med. 360: 1500-1508.
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 1500-1508
-
-
Van Marken-Lichtenbelt, W.D.1
Vanhommerig, J.W.2
Smulders, N.M.3
Drossaerts, J.M.4
Kemerink, G.J.5
Bouvy, N.D.6
Schrauwen, P.7
Teule, G.J.8
-
3
-
-
64349123664
-
Functional brown adipose tissue in healthy adults
-
Virtanen, K. A., M. E. Lidell, J. Orava, M. Heglind, R. Westergren, T. Niemi, M. Taittonen, J. Laine, N. J. Savisto, S. Enerback, et al. 2009. Functional brown adipose tissue in healthy adults. N. Engl. J. Med. 360: 1518-1525.
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 1518-1525
-
-
Virtanen, K.A.1
Lidell, M.E.2
Orava, J.3
Heglind, M.4
Westergren, R.5
Niemi, T.6
Taittonen, M.7
Laine, J.8
Savisto, N.J.9
Enerback, S.10
-
4
-
-
84861037753
-
The holy grail of metabolic disease: Brown adipose tissue
-
Bartelt, A., and J. Heeren. 2012. The holy grail of metabolic disease: brown adipose tissue. Curr. Opin. Lipidol. 23: 190-195.
-
(2012)
Curr. Opin. Lipidol.
, vol.23
, pp. 190-195
-
-
Bartelt, A.1
Heeren, J.2
-
6
-
-
0037034257
-
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
-
Knowler, W. C., E. Barrett-Connor, S. E. Fowler, R. F. Hamman, J. M. Lachin, E. A. Walker, and D. M. Nathan; Diabetes Prevention Program Research Group. 2002. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N. Engl. J. Med. 346: 393-403.
-
(2002)
N. Engl. J. Med.
, vol.346
, pp. 393-403
-
-
Knowler, W.C.1
Barrett-Connor, E.2
Fowler, S.E.3
Hamman, R.F.4
Lachin, J.M.5
Walker, E.A.6
Nathan, D.M.7
-
7
-
-
78650098848
-
Outdoor temperature, age, sex, body mass index, and diabetic status determine the prevalence, mass, and glucose-uptake activity of 18F-FDG detected BAT in humans
-
Ouellet, V., A. Routhier-Labadie, W. Bellemare, L. Lakhal-Chaieb, E. Turcotte, A. C. Carpentier, and D. Richard. 2011. Outdoor temperature, age, sex, body mass index, and diabetic status determine the prevalence, mass, and glucose-uptake activity of 18F-FDG detected BAT in humans. J. Clin. Endocrinol. Metab. 96: 192-199.
-
(2011)
J. Clin. Endocrinol. Metab.
, vol.96
, pp. 192-199
-
-
Ouellet, V.1
Routhier-Labadie, A.2
Bellemare, W.3
Lakhal-Chaieb, L.4
Turcotte, E.5
Carpentier, A.C.6
Richard, D.7
-
8
-
-
84881221754
-
Recruited brown adipose tissue as an antiobesity agent in humans
-
Yoneshiro, T., S. Aita, M. Matsushita, T. Kayahara, T. Kameya, Y. Kawai, T. Iwanaga, and M. Saito. 2013. Recruited brown adipose tissue as an antiobesity agent in humans. J. Clin. Invest. 123: 3404-3408.
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 3404-3408
-
-
Yoneshiro, T.1
Aita, S.2
Matsushita, M.3
Kayahara, T.4
Kameya, T.5
Kawai, Y.6
Iwanaga, T.7
Saito, M.8
-
9
-
-
84881260642
-
Cold acclimation recruits human brown fat and increases nonshivering thermogenesis
-
van der Lans, A. A., J. Hoeks, B. Brans, G. H. Vijgen, M. G. Visser, M. J. Vosselman, J. Hansen, J. A. Jorgensen, J. Wu, F. M. Mottaghy, et al. 2013. Cold acclimation recruits human brown fat and increases nonshivering thermogenesis. J. Clin. Invest. 123: 3395-3403.
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 3395-3403
-
-
Van Der-Lans, A.A.1
Hoeks, J.2
Brans, B.3
Vijgen, G.H.4
Visser, M.G.5
Vosselman, M.J.6
Hansen, J.7
Jorgensen, J.A.8
Wu, J.9
Mottaghy, F.M.10
-
10
-
-
0347989317
-
Brown adipose tissue: Function and physiological significance
-
Cannon, B., and J. Nedergaard. 2004. Brown adipose tissue: function and physiological significance. Physiol. Rev. 84: 277-359.
-
(2004)
Physiol. Rev.
, vol.84
, pp. 277-359
-
-
Cannon, B.1
Nedergaard, J.2
-
11
-
-
80052139636
-
Age-related decrease in cold-activated brown adipose tissue and accumulation of body fat in healthy humans
-
Yoneshiro, T., S. Aita, M. Matsushita, Y. Okamatsu-Ogura, T. Kameya, Y. Kawai, M. Miyagawa, M. Tsujisaki, and M. Saito. 2011. Age-related decrease in cold-activated brown adipose tissue and accumulation of body fat in healthy humans. Obesity (Silver Spring). 19: 1755-1760.
-
(2011)
Obesity (Silver Spring)
, vol.19
, pp. 1755-1760
-
-
Yoneshiro, T.1
Aita, S.2
Matsushita, M.3
Okamatsu-Ogura, Y.4
Kameya, T.5
Kawai, Y.6
Miyagawa, M.7
Tsujisaki, M.8
Saito, M.9
-
12
-
-
79751503329
-
Brown adipose tissue activity controls triglyceride clearance
-
Bartelt, A., O. T. Bruns, R. Reimer, H. Hohenberg, H. Ittrich, K. Peldschus, M. G. Kaul, U. I. Tromsdorf, H. Weller, C. Waurisch, et al. 2011. Brown adipose tissue activity controls triglyceride clearance. Nat. Med. 17: 200-205.
-
(2011)
Nat. Med.
, vol.17
, pp. 200-205
-
-
Bartelt, A.1
Bruns, O.T.2
Reimer, R.3
Hohenberg, H.4
Ittrich, H.5
Peldschus, K.6
Kaul, M.G.7
Tromsdorf, U.I.8
Weller, H.9
Waurisch, C.10
-
13
-
-
84874900503
-
Biochemistry and pathophysiology of intravascular and intracellular lipolysis
-
Young, S. G., and R. Zechner. 2013. Biochemistry and pathophysiology of intravascular and intracellular lipolysis. Genes Dev. 27: 459-484.
-
(2013)
Genes Dev.
, vol.27
, pp. 459-484
-
-
Young, S.G.1
Zechner, R.2
-
14
-
-
84873518501
-
Adaptive thermogenesis in adipocytes: Is beige the new brown?
-
Wu, J., P. Cohen, and B. M. Spiegelman. 2013. Adaptive thermogenesis in adipocytes: is beige the new brown? Genes Dev. 27: 234-250.
-
(2013)
Genes Dev.
, vol.27
, pp. 234-250
-
-
Wu, J.1
Cohen, P.2
Spiegelman, B.M.3
-
15
-
-
85027909934
-
Adipose tissue browning and metabolic health
-
Bartelt, A., and J. Heeren. 2014. Adipose tissue browning and metabolic health. Nat. Rev. Endocrinol. 10: 24-36.
-
(2014)
Nat. Rev. Endocrinol.
, vol.10
, pp. 24-36
-
-
Bartelt, A.1
Heeren, J.2
-
16
-
-
0034611678
-
Towards a molecular understanding of adaptive thermogenesis
-
Lowell, B. B., and B. M. Spiegelman. 2000. Towards a molecular understanding of adaptive thermogenesis. Nature. 404: 652-660.
-
(2000)
Nature
, vol.404
, pp. 652-660
-
-
Lowell, B.B.1
Spiegelman, B.M.2
-
17
-
-
0032253790
-
Thermogenesis is beta3-but not beta1-adrenergically mediated in rat brown fat cells, even after cold acclimation
-
Zhao, J., B. Cannon, and J. Nedergaard. 1998. Thermogenesis is beta3-but not beta1-adrenergically mediated in rat brown fat cells, even after cold acclimation. Am. J. Physiol. 275: R2002-R2011.
-
(1998)
Am. J. Physiol.
, vol.275
, pp. R2002-R2011
-
-
Zhao, J.1
Cannon, B.2
Nedergaard, J.3
-
18
-
-
84890234667
-
UCP1 in brite/beige adipose tissue mitochondria is functionally thermogenic
-
Shabalina, I. G., N. Petrovic, J. M. de Jong, A. V. Kalinovich, B. Cannon, and J. Nedergaard. 2013. UCP1 in brite/beige adipose tissue mitochondria is functionally thermogenic. Cell Reports. 5: 1196-1203.
-
(2013)
Cell Reports.
, vol.5
, pp. 1196-1203
-
-
Shabalina, I.G.1
Petrovic, N.2
De Jong, J.M.3
Kalinovich, A.V.4
Cannon, B.5
Nedergaard, J.6
-
19
-
-
84875879626
-
The endocannabinoid system in energy homeostasis and the etiopathology of metabolic disorders
-
Silvestri, C., and V. Di Marzo. 2013. The endocannabinoid system in energy homeostasis and the etiopathology of metabolic disorders. Cell Metab. 17: 475-490.
-
(2013)
Cell Metab.
, vol.17
, pp. 475-490
-
-
Silvestri, C.1
Di Marzo, V.2
-
20
-
-
77950199353
-
CB(1) signaling in forebrain and sympathetic neurons is a key determinant of endocannabinoid actions on energy balance
-
Quarta, C., L. Bellocchio, G. Mancini, R. Mazza, C. Cervino, L. J. Braulke, C. Fekete, R. Latorre, C. Nanni, M. Bucci, et al. 2010. CB(1) signaling in forebrain and sympathetic neurons is a key determinant of endocannabinoid actions on energy balance. Cell Metab. 11: 273-285.
-
(2010)
Cell Metab.
, vol.11
, pp. 273-285
-
-
Quarta, C.1
Bellocchio, L.2
Mancini, G.3
Mazza, R.4
Cervino, C.5
Braulke, L.J.6
Fekete, C.7
Latorre, R.8
Nanni, C.9
Bucci, M.10
-
21
-
-
82455168018
-
Cannabinoid receptor 1 (CB1) antagonism enhances glucose utilisation and activates brown adipose tissue in diet-induced obese mice
-
Bajzer, M., M. Olivieri, M. K. Haas, P. T. Pfluger, I. J. Magrisso, M. T. Foster, M. H. Tschop, K. A. Krawczewski-Carhuatanta, D. Cota, and S. Obici. 2011. Cannabinoid receptor 1 (CB1) antagonism enhances glucose utilisation and activates brown adipose tissue in diet-induced obese mice. Diabetologia. 54: 3121-3131.
-
(2011)
Diabetologia
, vol.54
, pp. 3121-3131
-
-
Bajzer, M.1
Olivieri, M.2
Haas, M.K.3
Pfluger, P.T.4
Magrisso, I.J.5
Foster, M.T.6
Tschop, M.H.7
Krawczewski-Carhuatanta, K.A.8
Cota, D.9
Obici, S.10
-
22
-
-
84919779595
-
Peripheral cannabinoid 1 receptor blockade activates brown adipose tissue and diminishes dyslipidemia and obesity
-
Boon, M. R., S. Kooijman, A. D. van Dam, L. R. Pelgrom, J. F. Berbee, C. A. Visseren, R. C. van Aggele, A. M. van den Hoek, H. C. Sips, M. Lombes, et al. 2014. Peripheral cannabinoid 1 receptor blockade activates brown adipose tissue and diminishes dyslipidemia and obesity. FASEB J. 28: 5361-5375.
-
(2014)
FASEB J.
, vol.28
, pp. 5361-5375
-
-
Boon, M.R.1
Kooijman, S.2
Van Dam, A.D.3
Pelgrom, L.R.4
Berbee, J.F.5
Visseren, C.A.6
Van Aggele, R.C.7
Van Den-Hoek, A.M.8
Sips, H.C.9
Lombes, M.10
-
23
-
-
84921628040
-
Cannabinoid type 1 (CB1) receptors on Sim1-expressing neurons regulate energy expenditure in male mice
-
Cardinal, P., L. Bellocchio, O. Guzman-Quevedo, C. Andre, S. Clark, M. Elie, T. Leste-Lasserre, D. Gonzales, A. Cannich, G. Marsicano, et al. 2015. Cannabinoid type 1 (CB1) receptors on Sim1-expressing neurons regulate energy expenditure in male mice. Endocrinology. 156: 411-418.
-
(2015)
Endocrinology
, vol.156
, pp. 411-418
-
-
Cardinal, P.1
Bellocchio, L.2
Guzman-Quevedo, O.3
Andre, C.4
Clark, S.5
Elie, M.6
Leste-Lasserre, T.7
Gonzales, D.8
Cannich, A.9
Marsicano, G.10
-
24
-
-
84928748528
-
Role of the endocannabinoid system in obesity induced by neuropeptide y overexpression in noradrenergic neurons
-
Vähätalo, L. H., S. T. Ruohonen, S. Mäkelä, L. Ailanen, A. M. Penttinen, T. Stormi, T. Kauko, F. Piscitelli, C. Silvestri, E. Savontaus, et al. 2015. Role of the endocannabinoid system in obesity induced by neuropeptide Y overexpression in noradrenergic neurons. Nutr. Diabetes. 5: e151.
-
(2015)
Nutr. Diabetes.
, vol.5
, pp. e151
-
-
Vähätalo, L.H.1
Ruohonen, S.T.2
Mäkelä, S.3
Ailanen, L.4
Penttinen, A.M.5
Stormi, T.6
Kauko, T.7
Piscitelli, F.8
Silvestri, C.9
Savontaus, E.10
-
25
-
-
73349119690
-
Cannabinoid type 1 receptor blockade induces transdifferentiation towards a brown fat phenotype in white adipocytes
-
Perwitz, N., J. Wenzel, I. Wagner, J. Buning, M. Drenckhan, K. Zarse, M. Ristow, W. Lilienthal, H. Lehnert, and J. Klein. 2010. Cannabinoid type 1 receptor blockade induces transdifferentiation towards a brown fat phenotype in white adipocytes. Diabetes Obes. Metab. 12: 158-166.
-
(2010)
Diabetes Obes. Metab.
, vol.12
, pp. 158-166
-
-
Perwitz, N.1
Wenzel, J.2
Wagner, I.3
Buning, J.4
Drenckhan, M.5
Zarse, K.6
Ristow, M.7
Lilienthal, W.8
Lehnert, H.9
Klein, J.10
-
26
-
-
84884212767
-
Cannabinoid type 1 receptor mediates depot-specific effects on differentiation, inflammation and oxidative metabolism in inguinal and epididymal white adipocytes
-
Wagner, I. V., N. Perwitz, M. Drenckhan, H. Lehnert, and J. Klein. 2011. Cannabinoid type 1 receptor mediates depot-specific effects on differentiation, inflammation and oxidative metabolism in inguinal and epididymal white adipocytes. Nutr. Diabetes. 1: e16.
-
(2011)
Nutr. Diabetes.
, vol.1
, pp. e16
-
-
Wagner, I.V.1
Perwitz, N.2
Drenckhan, M.3
Lehnert, H.4
Klein, J.5
-
27
-
-
80054692396
-
Altered endocannabinoid signalling after a high-fat diet in Apoe (-/-) mice: Relevance to adipose tissue inflammation, hepatic steatosis and insulin resistance
-
Bartelt, A., P. Orlando, C. Mele, A. Ligresti, K. Toedter, L. Scheja, J. Heeren, and V. Di Marzo. 2011. Altered endocannabinoid signalling after a high-fat diet in Apoe (-/-) mice: relevance to adipose tissue inflammation, hepatic steatosis and insulin resistance. Diabetologia. 54: 2900-2910.
-
(2011)
Diabetologia
, vol.54
, pp. 2900-2910
-
-
Bartelt, A.1
Orlando, P.2
Mele, C.3
Ligresti, A.4
Toedter, K.5
Scheja, L.6
Heeren, J.7
Di Marzo, V.8
-
28
-
-
0032549811
-
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
-
Puigserver, P., Z. Wu, C. W. Park, R. Graves, M. Wright, and B. M. Spiegelman. 1998. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell. 92: 829-839.
-
(1998)
Cell
, vol.92
, pp. 829-839
-
-
Puigserver, P.1
Wu, Z.2
Park, C.W.3
Graves, R.4
Wright, M.5
Spiegelman, B.M.6
-
29
-
-
0035185505
-
The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue
-
de Jesus, L. A., S. D. Carvalho, M. O. Ribeiro, M. Schneider, S. W. Kim, J. W. Harney, P. R. Larsen, and A. C. Bianco. 2001. The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue. J. Clin. Invest. 108: 1379-1385.
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1379-1385
-
-
De Jesus, L.A.1
Carvalho, S.D.2
Ribeiro, M.O.3
Schneider, M.4
Kim, S.W.5
Harney, J.W.6
Larsen, P.R.7
Bianco, A.C.8
-
30
-
-
25144456888
-
Differential regulation of fatty acid elongation enzymes in brown adipocytes implies a unique role for Elovl3 during increased fatty acid oxidation
-
Jakobsson, A., J. A. Jörgensen, and A. Jacobsson. 2005. Differential regulation of fatty acid elongation enzymes in brown adipocytes implies a unique role for Elovl3 during increased fatty acid oxidation. Am. J. Physiol. Endocrinol. Metab. 289: E517-E526.
-
(2005)
Am. J. Physiol. Endocrinol. Metab.
, vol.289
, pp. E517-E526
-
-
Jakobsson, A.1
Jörgensen, J.A.2
Jacobsson, A.3
-
31
-
-
37449007904
-
The acyclic CB1R inverse agonist taranabant mediates weight loss by increasing energy expenditure and decreasing caloric intake
-
Addy, C., H. Wright, K. Van Laere, I. Gantz, N. Erondu, B. J. Musser, K. Lu, J. Yuan, S. M. Sanabria-Bohorquez, A. Stoch, et al. 2008. The acyclic CB1R inverse agonist taranabant mediates weight loss by increasing energy expenditure and decreasing caloric intake. Cell Metab. 7: 68-78.
-
(2008)
Cell Metab.
, vol.7
, pp. 68-78
-
-
Addy, C.1
Wright, H.2
Van Laere, K.3
Gantz, I.4
Erondu, N.5
Musser, B.J.6
Lu, K.7
Yuan, J.8
Sanabria-Bohorquez, S.M.9
Stoch, A.10
-
33
-
-
35748940300
-
Role and regulation of acylethanolamides in energy balance: Focus on adipocytes and beta-cells
-
Matias, I., M. P. Gonthier, S. Petrosino, L. Docimo, R. Capasso, L. Hoareau, P. Monteleone, R. Roche, A. A. Izzo, and V. Di Marzo. 2007. Role and regulation of acylethanolamides in energy balance: focus on adipocytes and beta-cells. Br. J. Pharmacol. 152: 676-690.
-
(2007)
Br. J. Pharmacol.
, vol.152
, pp. 676-690
-
-
Matias, I.1
Gonthier, M.P.2
Petrosino, S.3
Docimo, L.4
Capasso, R.5
Hoareau, L.6
Monteleone, P.7
Roche, R.8
Izzo, A.A.9
Di Marzo, V.10
-
34
-
-
69549130581
-
Receptors for acylethanolamides-GPR55 and GPR119
-
Godlewski, G., L. Offertaler, J. A. Wagner, and G. Kunos. 2009. Receptors for acylethanolamides-GPR55 and GPR119. Prostaglandins Other Lipid Mediat. 89: 105-111.
-
(2009)
Prostaglandins Other Lipid Mediat.
, vol.89
, pp. 105-111
-
-
Godlewski, G.1
Offertaler, L.2
Wagner, J.A.3
Kunos, G.4
-
35
-
-
84973860969
-
The endocannabinoid system and its modulation by phytocannabinoids
-
Di Marzo, V., and F. Piscitelli. 2015. The endocannabinoid system and its modulation by phytocannabinoids. Neurotherapeutics. 12: 692-698.
-
(2015)
Neurotherapeutics
, vol.12
, pp. 692-698
-
-
Di Marzo, V.1
Piscitelli, F.2
-
36
-
-
84924667080
-
Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota
-
Geurts, L., A. Everard, M. Van Hul, A. Essaghir, T. Duparc, S. Matamoros, H. Plovier, J. Castel, R. G. Denis, M. Bergiers, et al. 2015. Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota. Nat. Commun. 6: 6495
-
(2015)
Nat. Commun.
, vol.6
, pp. 6495
-
-
Geurts, L.1
Everard, A.2
Van Hul, M.3
Essaghir, A.4
Duparc, T.5
Matamoros, S.6
Plovier, H.7
Castel, J.8
Denis, R.G.9
Bergiers, M.10
|