Benzoyl chloride derivatization with liquid chromatography-mass spectrometry for targeted metabolomics of neurochemicals in biological samples

Journal of Chromatography A

Volumn 1446, Issue , 2016, Pages 78-90

  Wong, Jenny Marie T ^a   Malec, Paige A ^a   Mabrouk, Omar S ^a,b   Ro, Jennifer ^a   Dus, Monica ^a   Kennedy, Robert T ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Brain; Derivatization; Drosophila; HPLC; Mass spectrometry; Neurochemistry

Indexed keywords

AMINES; ASSAYS; BIOCHEMISTRY; BODY FLUIDS; BRAIN; CEREBROSPINAL FLUID; CHLORINE COMPOUNDS; CHROMATOGRAPHY; DRUG PRODUCTS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES; PHYSIOLOGICAL MODELS; PHYSIOLOGY; SPECTROMETRY;

DERIVATIZATIONS; DROSOPHILA; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRIES; HPLC; HUMAN CEREBROSPINAL FLUID; LIQUID CHROMATOGRAPHY - MASS SPECTROMETRIES; NEUROCHEMISTRY; RELATIVE STANDARD DEVIATIONS;

LIQUID CHROMATOGRAPHY;

3 O METHYLDOPAMINE; 3,4 DIHYDROXYPHENYLACETIC ACID; 4 AMINOBUTYRIC ACID; 5 HYDROXYINDOLEACETIC ACID; ACETYLCHOLINE; ADENOSINE; AMINE; AMINO ACID; ANTIOXIDANT; ASPARTIC ACID; BENZOYL CHLORIDE; CATECHOLAMINE; CHLORIDE; CHOLINE; CYSTEIC ACID; DOPAMINE; GLUTAMIC ACID; GLYCINE; HISTAMINE; HISTIDINE; HOMOVANILLIC ACID; INDOLEAMINE; NEUROTRANSMITTER; NORADRENALIN; NORMETADRENALIN; POLYAMINE; SERINE; SEROTONIN; TAURINE; UNCLASSIFIED DRUG; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; BENZOIC ACID DERIVATIVE;

ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; CEREBROSPINAL FLUID ANALYSIS; CONTROLLED STUDY; DERIVATIZATION; DIALYSATE; DROSOPHILA; HEMOLYMPH; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INSECT; LIMIT OF DETECTION; MALE; METABOLOMICS; NEUROCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; RAT; SAMPLE SIZE; TANDEM MASS SPECTROMETRY; TISSUE HOMOGENATE; VERTEBRATE; ANIMAL; BLOOD; CEREBROSPINAL FLUID; CHEMISTRY; METABOLOME; PROCEDURES; SPECIES DIFFERENCE; SPRAGUE DAWLEY RAT;

AMINO ACIDS; ANIMALS; BENZOATES; CATECHOLAMINES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DROSOPHILA; HEMOLYMPH; HUMANS; METABOLOME; METABOLOMICS; NEUROTRANSMITTER AGENTS; RATS; RATS, SPRAGUE-DAWLEY; SPECIES SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 84963830628     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2016.04.006     Document Type: Article

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