Improvement of Sensitivity for the Determination of Propylene Glycol in Rat Plasma and Lung Tissue Using HPLC/Tandem MS and Derivatization with Benzoyl Chloride

Journal of Liquid Chromatography and Related Technologies

Volumn 26, Issue 20, 2003, Pages 3413-3431

  Gao, Songmei ^a   Wilson, David M ^a   Edinboro, Leslie E ^a   McGuire, Gerard M ^b   Williams, Stephen G P ^b   Karnes, H Thomas ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Inveresk Research   (United Kingdom)

Author keywords

Aerosol; APCI; Benzoyl chloride; Derivatization; LC MS MS; Perfluorooetanoyl chloride

Indexed keywords

DRUG PRODUCTS; IONIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; TISSUE;

THAW STABILITY;

ORGANIC COMPOUNDS;

1,4 BUTANEDIOL; CHLORIDE; METHANOL; PENTANE; PERFLUORO COMPOUND; PERFLUOROOCTANOIC ACID; PROPYLENE GLYCOL; REAGENT;

AEROSOL; ANALYTIC METHOD; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DERIVATIZATION; DRUG DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; LUNG; NONHUMAN; PLASMA; RAT; TANDEM MASS SPECTROMETRY;

ANIMALIA;

EID: 0346250958     PISSN: 10826076     EISSN: None     Source Type: Journal    
DOI: 10.1081/JLC-120025599     Document Type: Article

References (22)

1. Bailey, D.N. Propylene glycol as a vehicle for percutaneous absorption of therapeutic agents. J. Anal. Toxicol. 1992, 16, 97-98.
2. LaKind, J.S.; McKenna, E.A.; Hubner, R.P.; Tardiff, R.G. A review of the comparative mammalian toxicity of ethylene glycol and propylene glycol. Crit. Rev. Toxicol. 1999, 29 (4), 331-365.
3. Demey, H.E.; Daelemans, R.A.; Veropooten, G.A.; De Broe, M.E.; Van Campenhout, Ch.M.; Lakiere, EV.; Schepens, P.J.; Bossaert, L.L. Propylene glycol-induced side effects during intravenous nitroglycerin therapy. Intens. Care. Med. 1988, 14, 221-226.
4. Dasgupta, A.; Macaulay, R. A novel derivatization of ethylene glycol from human serum using 4-carbethoxyhexafluorobutyryl chloride for unambiguous gas chromatography-chemical ionization mass spectrometric identification and quantification. Am. J. Clin. Pathol. 1995, 104 (3), 283-288.
5. Williams, R.H.; Shah, S.M.; Maggiore, J.A.; Erickson, T.B. Simultaneous detection and quantitation of diethylene glycol, ethylene glycol, and the toxic alcohols in serum using capillary column gas chromatography. J. Anal. Toxicol. 2000, 24, 621-626.
6. Baffi, P.; Elneser, S.; Baffi, M.; De Melin, M. Quantitative determination of diethylene glycol contamination in pharmaceutical products. J. AOAC 2000, 83, 793-801.
7. Iwinski, G.; Jenke, D.R. Determination of alcohols in pharmaceuticals by ion-exclusion chromatography. J. Chromatogr. 1987, 392, 397-405.
8. Ferrala, N.E; Ghanayem, B.I.; Nomeir, A.A. Determination of 1-methoxy-2-propanol and its metabolite 1,2-propanediol in rat and mouse plasma by gas chromatography. J. Chromatogr. B 1994, 660, 291-296.
9. Yu, D.K.; Sawchuk, R.J. Gas-Liquid chromatogrphic determination of propylene glycol in plasma and urine. Clin. Chem. 1983, 29, 2088-2090.
10. Bayer, E.; Gfrorer, P.; Rentel, C. Coordination-ionspray-MS (CIS-MS), a universal detection and characterization method for direct coupling with separation techniques. Angew. Chem. Int. Ed. 1999, 38, 992-995.
11. Van Berkel, G.J.; Quirke, J.M.E.; Tigani, R.A.; Dilley A.S.; Covey, T.R. Derivatization for electrospray ionization mass spectrometry. 3. Electrochemically ionizable derivatives. Anal. Chem. 1998, 70, 1544-1554.
12. Vollmer, P.A.; Harty, D.C.; Erickson, N.B.; Balhon, A.C.; Dean, R.A. Serum ethylene glycol by high-performance liquid chromatography. J. Chromatogr. B 1996, 685, 370-374.
13. Higashi, T.; Awade, D.; Shimada, K. Determination of 24, 25-dihydroxyvitamin D3 in human plasma using liquid chromatography-mass spectrometry after derivatization with a cookson-type reagent. Biomed. Chromatogr. 2001, 15, 133-140.
14. Novak, T.J.; Yuan, H. The determination of a chlorinated benzofuran pharmaceutical intermediate by HPLC-MS with on-line derivatization. J. Pharm. Biomed. Anal. 2000, 23, 705-713.
15. Gupta, R.N. Determination of trichloroethanol, the active metabolite of chloral hydrate, in plasma by liquid chromatography. J. Chromatogr. 1990, 500, 655-659.
16. Mei, Y.H. A sensitive and fast method for the determination of polyamines in biological samples. Benzoyl chloride pre-column derivatization high-performance liquid chromatography. J. Liq. Chromatogr. 1994, 17, 2413-2418.
17. Sunner, J.; Nicol, G.; Kebarle, P. Factors determining relative sensitive of analytes in positive mode atmospheric pressure ionization mass spectrometry. Anal. Chem. 1988, 60, 1300-1307.
18. Sunner, J.; Ikonomou, M.G.; Kebarle, P. Sensitivity enhancements obtained at high temperatures in atmospheric pressure ionization mass spectrometry. Anal. Chem. 1988, 60, 1308-1313.
19. Reemtsma, T. Analysis of sulfophthalimide and some of its derivatives by liquid chromatographyelectrospray ionization tandem mass spectrometry. J. Chromatogr. A 2001, 919, 289-297.
20. Hunt, D.F.; Stafford, G.C., Jr.; Crow, F.W.; Russell, J.W. Pulsed positive negative ion chemical ionization mass spectrometry. Anal. Chem. 1976, 48, 2098-2104.
21. Singh, G.; Gutierrex, A.; Xu, K.; Blair, I.A. Liquid chromatography/electron capture atmospheric pressure chemical ionization/mass spectrometry: analysis of pentafluorobenzyl derivatives of biomolecules and drugs in the attomole range. Anal. Chem. 2000, 72, 3007-3013.
22. Dasgupta, A.; Blackwell, W.; Griego, J.; Malik, S. Gas chromatographicmass spectrometric identification and quantitation of ethylene glycol in serum after derivatization with perfluorooctanoyl chloride: a novel derivative. J. Chromatogr. B 1995, 666, 63-70.