Intrauterine Exposure to Paracetamol and Aniline Impairs Female Reproductive Development by Reducing Follicle Reserves and Fertility

Toxicological Sciences

Volumn 150, Issue 1, 2016, Pages 178-189

  Holm, Jacob Bak ^a   Mazaud Guittot, Severine ^b   Danneskiold Samsøe, Niels Banhos ^a   Chalmey, Clementine ^b   Jensen, Benjamin ^a   Nørregård, Mette Marie ^a   Hansen, Cecilie Hurup ^c   Styrishave, Bjarne ^c   Svingen, Terje ^d   Vinggaard, Anne Marie ^d   Koch, Holger Martin ^e   Bowles, Josephine ^f   Koopman, Peter ^f   Jégou, Bernard ^b,g   Kristiansen, Karsten ^a   Kristensen, David Møbjerg ^a,b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITÉ DE RENNES 1   (France)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^e RUHR UNIVERSITY BOCHUM   (Germany)

^f UNIVERSITY OF QUEENSLAND   (Australia)

^g EHESP SCHOOL OF PUBLIC HEALTH   (France)

Author keywords

Aniline; Development; Follicle reserves; Intrauterine exposure; Paracetamol acetaminophen; Reproduction

Indexed keywords

ANILINE; HORMONE; PARACETAMOL; ANILINE DERIVATIVE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANOGENITAL DISTANCE; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CELL COUNT; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DEVELOPMENTAL STAGE; EMBRYO; EMBRYONIC STEM CELL; EX VIVO STUDY; FEMALE; FEMALE SUBFERTILITY; FETUS; GERM CELL; GONAD DYSFUNCTION; MOUSE; NEWBORN; NONHUMAN; OVARIAN RESERVE; OVARY FOLLICLE; PRENATAL DRUG EXPOSURE; PRIMORDIAL GERM CELL; PROGENY; REPRODUCTIVE TOXICITY; SIGNAL TRANSDUCTION; ABNORMALITIES; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; DRUG EFFECTS; EMBRYOLOGY; FEMALE GENITAL SYSTEM; FERTILITY; GESTATIONAL AGE; MALE; PATHOLOGY; PATHOPHYSIOLOGY; PREGNANCY; PRENATAL EXPOSURE;

ACETAMINOPHEN; ANILINE COMPOUNDS; ANIMALS; FEMALE; FERTILITY; GENITALIA, FEMALE; GESTATIONAL AGE; MALE; MICE, INBRED C57BL; OVARIAN FOLLICLE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS;

EID: 84963829090     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfv332     Document Type: Article

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