Maternal use of acetaminophen, ibuprofen, and acetylsalicylic acid during pregnancy and risk of cryptorchidism

Epidemiology

Volumn 21, Issue 6, 2010, Pages 779-785

  Jensen, Morten Søndergaard ^a   Rebordosa, Cristina ^b   Thulstrup, Ane Marie ^a   Toft, Gunnar ^a   Sørensen, Henrik Toft ^a,c   Bonde, Jens Peter ^d   Henriksen, Tine Brink ^a   Olsen, Jørn ^e,f  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b UNIVERSITY OF ARIZONA   (United States)

^c BOSTON UNIVERSITY   (United States)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

^e AARHUS UNIVERSITY   (Denmark)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; IBUPROFEN; PARACETAMOL;

ADULT; ARTICLE; CRYPTORCHISM; FEMALE; FIRST TRIMESTER PREGNANCY; HUMAN; MAJOR CLINICAL STUDY; MALE; ORCHIDOPEXY; PREGNANCY; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; QUESTIONNAIRE; RISK; SECOND TRIMESTER PREGNANCY;

ACETAMINOPHEN; ADULT; ASPIRIN; CRYPTORCHIDISM; CYCLOOXYGENASE INHIBITORS; DENMARK; FEMALE; HUMANS; IBUPROFEN; MALE; MATERNAL EXPOSURE; PREGNANCY;

EID: 77958482536     PISSN: 10443983     EISSN: None     Source Type: Journal    
DOI: 10.1097/EDE.0b013e3181f20bed     Document Type: Article

References (37)

1. Chacko JK, Barthold JS. Genetic and environmental contributors to cryptorchidism. Pediatr Endocrinol Rev. 2009;6:476-480.
2. Cortes D, Kjellberg EM, Breddam M, Thorup J. The true incidence of cryptorchidism in Denmark. J Urol. 2008;179:314-318.
3. Jensen MS, Toft G, Thulstrup AM, et al. Cryptorchidism concordance in mono-and dizygotic twin brothers, full brothers and half brothers. Fertil Steril. 2010;93:124-129.
4. Welsh M, Saunders PT, Fisken M, et al. Identification in rats of a programming window for reproductive tract masculinization, disruption of which leads to hypospadias and cryptorchidism. J Clin Invest. 2008; 118:1479-1490.
5. Amann RP, Veeramachaneni DN. Cryptorchidism in common eutherian mammals. Reproduction. 2007;133:541-561.
6. Clements JA, Reyes FI, Winter JS, Faiman C. Studies on human sexual development. III. Fetal pituitary and serum, and amniotic fluid concentrations of LH, CG, and FSH. J Clin Endocrinol Metab. 1976;42:9-19.
7. Toppari J, Kaleva M, Virtanen HE, Main KM, Skakkebaek NE. Luteinizing hormone in testicular descent. Mol Cell Endocrinol. 2007; 269:34-37.
8. Huhtaniemi IT, Korenbrot CC, Jaffe RB. HCG binding and stimulation of testosterone biosynthesis in the human fetal testis. J Clin Endocrinol Metab. 1977;44:963-967.
9. Didolkar AK, Gurjar A, Joshi UM, Sheth AR, Roychowdhury D. Effect of prostaglandins A-1, E-2 and F-2 alpha on blood plasma levels of testosterone, LH and FSH in male rats. Andrologia. 1981;13:50-55.
10. Frungieri MB, Gonzalez-Calvar SI, Parborell F, Albrecht M, Mayerhofer A, Calandra RS. Cyclooxygenase-2 and prostaglandin F2 alpha in Syrian hamster Leydig cells: inhibitory role on luteinizing hormone/human chorionic gonadotropin-stimulated testosterone production. Endocrinology. 2006;147:4476-4485.
11. Romanelli F, Valenca M, Conte D, Isidori A, Negro-Vilar A. Arachidonic acid and its metabolites effects on testosterone production by rat Leydig cells. J Endocrinol Invest. 1995;18:186-193.
12. Stocco DM, Wang XJ, Jo Y, Manna PR. Multiple signaling pathways regulating steroidogenesis and steroidogenic acute regulatory protein expression: more complicated than we thought. Mol Endocrinol. 2005; 19:2647-2659.
13. Gravel A, Vijayan MM. Salicylate disrupts interrenal steroidogenesis and brain glucocorticoid receptor expression in rainbow trout. Toxicol Sci. 2006;93:41-49.
14. Conte D, Romanelli F, Fillo S, et al. Aspirin inhibits androgen response to chorionic gonadotropin in humans. Am J Physiol. 1999;277:E1032-E1037.
15. Schoenfeld A, Bar Y, Merlob P, Ovadia Y. NSAIDs: maternal and fetal considerations. Am J Reprod Immunol. 1992;28:141-147.
16. Rayburn W, Shukla U, Stetson P, Piehl E. Acetaminophen pharmaco-kinetics: comparison between pregnant and nonpregnant women. Am J Obstet Gynecol. 1986;155:1353-1356.
17. Rao P, Knaus EE. Evolution of nonsteroidal anti-inflammatory drugs (NSAIDs): cyclooxygenase (COX) inhibition and beyond. J Pharm Pharm Sci. 2008;11:81s-110s.
18. Graham GG, Scott KF. Mechanism of action of paracetamol. Am J Ther. 2005;12:46-55.
19. Anderson BJ. Paracetamol (Acetaminophen): mechanisms of action. Paediatr Anaesth. 2008;18:915-921.
20. Aronoff DM, Oates JA, Boutaud O. New insights into the mechanism of action of acetaminophen: its clinical pharmacologic characteristics reflect its inhibition of the two prostaglandin H2 synthases. Clin Pharmacol Ther. 2006;79:9-19.
21. Rebordosa C, Kogevinas M, Horvath-Puho E, et al. Acetaminophen use during pregnancy: effects on risk for congenital abnormalities. Am J Obstet Gynecol. 2008;198:178.e1-e7.
22. Dolk H. EUROCAT: 25 years of European surveillance of congenital anomalies. Arch Dis Child Fetal Neonatal Ed. 2005;90:F355-F358.
23. Olsen J, Melbye M, Olsen SF, et al. The Danish National Birth Cohort\-its background, structure and aim. Scand J Public Health. 2001;29:300-307.
24. McGlynn KA, Graubard BI, Klebanoff MA, Longnecker MP. Risk factors for cryptorchism among populations at differing risks of testic-ular cancer. Int J Epidemiol. 2006;35:787-795.
25. Jones ME, Swerdlow AJ, Griffith M, Goldacre MJ. Prenatal risk factors for cryptorchidism: a record linkage study. Paediatr Perinat Epidemiol. 1998;12:383-396.
26. Akre O, Lipworth L, Cnattingius S, Sparen P, Ekbom A. Risk factor patterns for cryptorchidism and hypospadias. Epidemiology. 1999;10: 364-369.
27. Jensen MS, Toft G, Thulstrup AM, Bonde JP, Olsen J. Cryptorchidism according to maternal gestational smoking. Epidemiology. 2007;18: 220-225.
28. Andersen TF, Madsen M, Jorgensen J, Mellemkjoer L, Olsen JH. The Danish National Hospital Register. A valuable source of data for modern health sciences. Dan Med Bull. 1999;46:263-268.
29. Wohlfahrt-Veje C, Boisen KA, Boas M, et al. Acquired cryptorchidism is frequent in infancy and childhood. Int J Androl. 2009;32:423-428.
30. Jensen MS, Bonde JP, Olsen J. Prenatal alcohol exposure and cryp-torchidism. Acta Paediatr. 2007;96:1681-1685.
31. Weidner IS, Moller H, Jensen TK, Skakkebaek NE. Risk factors for cryptorchidism and hypospadias. J Urol. 1999;161:1606-1609.
32. Virtanen HE, Tapanainen AE, Kaleva MM, et al. Mild gestational diabetes as a risk factor for congenital cryptorchidism. J Clin Endocrinol Metab. 2006;91:4862-4865.
33. Palmer JR, Herbst AL, Noller KL, et al. Urogenital abnormalities in men exposed to diethylstilbestrol in utero: a cohort study. Environ Health. 2009;8:37.
34. Nohr EA, Frydenberg M, Henriksen TB, Olsen J. Does low participation in cohort studies induce bias? Epidemiology. 2006;17:413-418.
35. Olesen C, Sondergaard C, Thrane N, Nielsen GL, de Jong-van den Berg L, Olsen J. Do pregnant women report use of dispensed medications? Epidemiology. 2001;12:497-501.
36. Reddy GP, Prasad M, Sailesh S, Kumar YV, Reddanna P. Arachidonic acid metabolites as intratesticular factors controlling androgen production. Int J Androl. 1993;16:227-233.
37. Wang X, Dyson MT, Jo Y, Stocco DM. Inhibition of cyclooxygenase-2 activity enhances steroidogenesis and steroidogenic acute regulatory gene expression in MA-10 mouse Leydig cells. Endocrinology. 2003; 144:3368-3375.