Prolonged exposure to acetaminophen reduces testosterone production by the human fetal testis in a xenograft model

Science translational medicine

Volumn 7, Issue 288, 2015, Pages

  van den Driesche, Sander ^a   Macdonald, Joni ^a   Anderson, Richard A ^a   Johnston, Zoe C ^a   Chetty, Tarini ^a   Smith, Lee B ^a   McKinnell, Chris ^a   Dean, Afshan ^a   Homer, Natalie Z ^a   Jorgensen, Anne ^a   Camacho Moll, Maria E ^a   Sharpe, Richard M ^a   Mitchell, Rod T ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CYP17A1 PROTEIN, RAT; PARACETAMOL; STEROID 17ALPHA MONOOXYGENASE; TESTOSTERONE;

ANIMAL; BIOSYNTHESIS; BLOOD; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECTS; EMBRYOLOGY; FEMALE; GRAFT SURVIVAL; GROWTH, DEVELOPMENT AND AGING; HUMAN; MALE; METABOLISM; MOUSE; ORCHIECTOMY; ORGAN SIZE; PREGNANCY; RAT; RISK ASSESSMENT; SEMINAL VESICLE; TESTIS; TIME FACTOR; XENOGRAFT;

ACETAMINOPHEN; ANIMALS; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; FEMALE; GRAFT SURVIVAL; HETEROGRAFTS; HUMANS; MALE; MICE; ORCHIECTOMY; ORGAN SIZE; PREGNANCY; RATS; RISK ASSESSMENT; SEMINAL VESICLES; STEROID 17-ALPHA-HYDROXYLASE; TESTIS; TESTOSTERONE; TIME FACTORS;

EID: 85013717382     PISSN: None     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aaa4097     Document Type: Article

References (0)