메뉴 건너뛰기




Volumn 27, Issue 2, 2016, Pages 350-356

The effects of aqueous ginger extract on pancreas histology and on blood glucose in normal and alloxan monohydrate-induced diabetic rats

Author keywords

Diabetes mellitus; Light microscope; Lipid profile; Zingiberaceae

Indexed keywords

ALLOXAN; CHOLESTEROL; GINGER EXTRACT; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

EID: 84963829061     PISSN: 0970938X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (25)

References (43)
  • 1
    • 0037822245 scopus 로고    scopus 로고
    • Diabetes mellitus and multiple therapeutic approaches of phytochemicals: Present status and future prospects
    • Tiwari AK, Rao JM (2002) Diabetes mellitus and multiple therapeutic approaches of phytochemicals: Present status and future prospects. Curr Sci 83: 30-38.
    • (2002) Curr Sci , vol.83 , pp. 30-38
    • Tiwari, A.K.1    Rao, J.M.2
  • 2
    • 84963914327 scopus 로고    scopus 로고
    • Guyton & Hall, ’s textbook of medical physiology. 11th ed, PA: Saunders
    • Hall JE. Secretory function of the alimentary tract. Guyton & Hall’s textbook of medical physiology. 11th ed. 2006; Philadelphia, PA: Saunders. pp: 791-807.
    • (2006) Secretory Function of the Alimentary Tract , pp. 791-807
    • Hall, J.E.1
  • 3
    • 84958965618 scopus 로고    scopus 로고
    • The effects of experimental aflatoxicosis on the pancreas of adult male albino rats and the role of ginger supplementation: A histological and biochemical study
    • Abd El-Haleem MR, Mohamed DA. The effects of experimental aflatoxicosis on the pancreas of adult male albino rats and the role of ginger supplementation: a histological and biochemical study. The Egyptian Journal of Histology 2011; 34: 423-435.
    • (2011) The Egyptian Journal of Histology , vol.34 , pp. 423-435
    • Abd El-Haleem, M.R.1    Mohamed, D.A.2
  • 4
    • 2142650337 scopus 로고    scopus 로고
    • Population perspective on diabetes prevention: Whom should we target for preventing weight gain?
    • Burke JP, Williams K, Narayan KMV, Leibson C, Haffner SM, Stern MP. A population perspective on diabetes prevention: Whom should we target for preventing weight gain? Diabetes Care. 2003; 26: 1999-2004.
    • (2003) Diabetes Care , vol.26 , pp. 1999-2004
    • Burke, J.P.1    Williams, K.2    Narayan, K.3    Leibson, C.4    Haffner, S.M.5    Stern, M.6
  • 5
    • 84896321997 scopus 로고    scopus 로고
    • Evaluation of Nutritional and Antidiabetic Activity of Different Forms of Ginger in Rats
    • Anfenan MLK. Evaluation of Nutritional and Antidiabetic Activity of Different Forms of Ginger in Rats. Middle-East Journal of Scientific Research 2014; 21: 56-62.
    • (2014) Middle-East Journal of Scientific Research , vol.21 , pp. 56-62
    • Anfenan, M.L.K.1
  • 6
    • 84963906713 scopus 로고    scopus 로고
    • Kalsoom. Effect of Murraya Koenigii, Catharanthus Roseus and Psidium Guajava Leaves Extract on Blood Glucose in Alloxan Induced Diabetic Rats
    • Jafri SA, Rehman K, Qasim M, Kalsoom. Effect of Murraya Koenigii, Catharanthus Roseus and Psidium Guajava Leaves Extract on Blood Glucose in Alloxan Induced Diabetic Rats. Am J Biol Life Sci 2014; 2: 1-5.
    • (2014) Am J Biol Life Sci , vol.2 , pp. 1-5
    • Jafri, S.A.1    Rehman, K.2    Qasim, M.3
  • 7
    • 80052220096 scopus 로고    scopus 로고
    • Fucoidan from marine brown algae inhibits lipid accumulation
    • Park MK, Jung U, Roh C. Fucoidan from marine brown algae inhibits lipid accumulation. Drugs 2011; 9: 1359-1367.
    • (2011) Drugs , vol.9 , pp. 1359-1367
    • Park, M.K.1    Jung, U.2    Roh, C.3
  • 8
    • 77954221888 scopus 로고    scopus 로고
    • A study of the antidiabetic activity of Barleria prionitis Linn
    • Dheer R, Bhatnagar P. A study of the antidiabetic activity of Barleria prionitis Linn. Indian J Pharmacol 2010; 42: 70-73.
    • (2010) Indian J Pharmacol , vol.42 , pp. 70-73
    • Dheer, R.1    Bhatnagar, P.2
  • 9
    • 79960749840 scopus 로고    scopus 로고
    • Antidiabetic effects of an alcoholic extract of Juglans regia in an animal model
    • Mohommadi J, Saadipour K, Delaviz H, Mohommadi B. Antidiabetic effects of an alcoholic extract of Juglans regia in an animal model. Turk J Med Sci 2011; 41: 685-91.
    • (2011) Turk J Med Sci , vol.41 , pp. 685-691
    • Mohommadi, J.1    Saadipour, K.2    Delaviz, H.3    Mohommadi, B.4
  • 10
    • 85015274941 scopus 로고    scopus 로고
    • Study of antihyperglycaemic activity of medicinal plant extracts in alloxan induced diabetic rats
    • Anoja PA, Kamani APW, Lakmini KBM. Study of antihyperglycaemic activity of medicinal plant extracts in alloxan induced diabetic rats. Anc Sci Life 2013; 32: 193-198.
    • (2013) Anc Sci Life , vol.32 , pp. 193-198
    • Anoja, P.A.1    Kamani, A.2    Lakmini, K.B.M.3
  • 11
    • 84878900612 scopus 로고    scopus 로고
    • Ginger. In: Parthasarathy VA, Champakam B, Zachariah TG. editors, CABI
    • Zachariah TJ. Ginger. In: Parthasarathy VA, Champakam B, Zachariah TG. editors. Chemistry of Spices 2008; CABI, pp: 70-100.
    • (2008) Chemistry of Spices , pp. 70-100
    • Zachariah, T.J.1
  • 12
    • 84963910295 scopus 로고    scopus 로고
    • The Effect of Ginger on The Histopatholoical Lesions of Salmonella Typhimurium in Mice Liver in Comparison with Cephalexin
    • Shinashal RZ, AL-Sultan RK, Abdalmajeed SA. The Effect of Ginger on The Histopatholoical Lesions of Salmonella Typhimurium in Mice Liver in Comparison with Cephalexin. J Kirkuk Univ Sci Stud 2012; 7: 14-23.
    • (2012) J Kirkuk Univ Sci Stud , vol.7 , pp. 14-23
    • Shinashal, R.Z.1    Al-Sultan, R.K.2    Abdalmajeed, S.A.3
  • 13
    • 37349127807 scopus 로고    scopus 로고
    • Some phytochemical, pharmacological and toxicological properties of Ginger (Zingiber officinale Roscoe), a review of recent research
    • Ali B, Tanira G, Nemmar A. Some phytochemical, pharmacological and toxicological properties of Ginger (Zingiber officinale Roscoe), a review of recent research. Food chem Toxicol 2008; 46: 409-420.
    • (2008) Food Chem Toxicol , vol.46 , pp. 409-420
    • Ali, B.1    Tanira, G.2    Nemmar, A.3
  • 14
    • 1642453609 scopus 로고    scopus 로고
    • Effects of ginger (Zingiber officinale Rosc.) on decreasing the production of inflammatory mediators in sow osteoarthritic cartilage explants
    • Shen CL, Hong KJ, Kim SW. Effects of ginger (Zingiber officinale Rosc.) on decreasing the production of inflammatory mediators in sow osteoarthritic cartilage explants. J Med Food 2003; 6: 323-328.
    • (2003) J Med Food , vol.6 , pp. 323-328
    • Shen, C.L.1    Hong, K.J.2    Kim, S.W.3
  • 15
    • 0024791488 scopus 로고
    • Ethnopharmacologic investigation of ginger (Zingiber officinale)
    • Mascolo N, Jain R, Jain SC, Capasso F. Ethnopharmacologic investigation of ginger (Zingiber officinale). J Ethnopharmacol 1989; 27: 129-140.
    • (1989) J Ethnopharmacol , vol.27 , pp. 129-140
    • Mascolo, N.1    Jain, R.2    Jain, S.C.3    Capasso, F.4
  • 16
    • 84878929056 scopus 로고    scopus 로고
    • Antihyperlipidemic effects of ginger extracts in alloxan-induced diabetes and propylthiouracil-induced hypothyroidism in (Rats)
    • Al-Noory AS, Amreen AN, Hymoor S. Antihyperlipidemic effects of ginger extracts in alloxan-induced diabetes and propylthiouracil-induced hypothyroidism in (rats). Phcog Res 2013; 5: 157-161.
    • (2013) Phcog Res , vol.5 , pp. 157-161
    • Al-Noory, A.S.1    Amreen, A.N.2    Hymoor, S.3
  • 17
    • 0025082064 scopus 로고
    • Effect of ginger & garlic on DNA content of gastric aspirate
    • Desai HG, Kalro RH, Choksi AP. Effect of ginger & garlic on DNA content of gastric aspirate. Indian J Med Res 1990; 92: 139-141.
    • (1990) Indian J Med Res , vol.92 , pp. 139-141
    • Desai, H.G.1    Kalro, R.H.2    Choksi, A.P.3
  • 18
    • 0021925418 scopus 로고
    • Immunoglobulin E antibodies against coriander and other spices
    • Van Toorenenbergen AW, Dieges PH. Immunoglobulin E antibodies against coriander and other spices. J Allergy Clin Immunol 1985; 76: 477-481.
    • (1985) J Allergy Clin Immunol , vol.76 , pp. 477-481
    • Van Toorenenbergen, A.W.1    Dieges, P.H.2
  • 20
    • 85091130454 scopus 로고    scopus 로고
    • Effect of Ginger extract consumption on levels of blood glucose, lipid profile and kidney functions in alloxan-induced diabetic rats
    • Elshater AA, Salman MMA, Moussa MMA. Effect of Ginger extract consumption on levels of blood glucose, lipid profile and kidney functions in alloxan-induced diabetic rats. Egypt Acad J Biol Sci 2009; 2: 153-162.
    • (2009) Egypt Acad J Biol Sci , vol.2 , pp. 153-162
    • Elshater, A.A.1    Salman, M.2    Moussa, M.M.A.3
  • 21
    • 3242714008 scopus 로고    scopus 로고
    • Effect of extracts of Murraya koengii leaves on levels of blood glucose and plasma insulin in alloxaninduced diabetic rats
    • Vinuthan MK, Girish KV, Ravindra JP, Jayaprakash, Narayana K. Effect of extracts of Murraya koengii leaves on levels of blood glucose and plasma insulin in alloxaninduced diabetic rats. Indian J Physiol Pharmacol 2004; 48: 348-352.
    • (2004) Indian J Physiol Pharmacol , vol.48 , pp. 348-352
    • Vinuthan, M.K.1    Girish, K.V.2    Ravindra, J.P.3    Jayaprakash, K.4
  • 22
    • 84897910155 scopus 로고    scopus 로고
    • Long-term effects of Nigella sativa L. Oil on some physiological parameters in normal and streptozotocin-induced diabetic rats
    • Al-Logmani A, Zari T. Long-term effects of Nigella sativa L. oil on some physiological parameters in normal and streptozotocin-induced diabetic rats. J Diab Mellit 2011; 1: 46-53.
    • (2011) J Diab Mellit , vol.1 , pp. 46-53
    • Al-Logmani, A.1    Zari, T.2
  • 24
    • 79960538539 scopus 로고    scopus 로고
    • Thujone corrects cholesterol and triglyceride profiles in diabetic rat model
    • Al-Haj Baddar NW, Aburjai TA, Taha MO, Disi AM. Thujone corrects cholesterol and triglyceride profiles in diabetic rat model. Nat Prod Rese 2011; 25: 1180-1184.
    • (2011) Nat Prod Rese , vol.25 , pp. 1180-1184
    • Al-Haj Baddar, N.W.1    Aburjai, T.A.2    Taha, M.O.3    Disi, A.M.4
  • 25
    • 84937931846 scopus 로고    scopus 로고
    • Safety Evaluation of Giant African land Snails (Archachatinamarginata) Haemolymph on Hematological and Biochemical Parameters of Albino Rats
    • Bashir L, Shittu OK, Busari MB, Sani S, Aisha MI. Safety Evaluation of Giant African land Snails (Archachatinamarginata) Haemolymph on Hematological and Biochemical Parameters of Albino Rats. J Adva Med Pharm Sci 2015; 3: 122-130.
    • (2015) J Adva Med Pharm Sci , vol.3 , pp. 122-130
    • Bashir, L.1    Shittu, O.K.2    Busari, M.B.3    Sani, S.4    Aisha, M.I.5
  • 26
    • 84885918282 scopus 로고    scopus 로고
    • Effect of Ginger, Curcumin and Their Mixture on Blood Glucose and Lipids in Diabetic Rats
    • Khattab HAH, Al-Amoudi NS, Al-Faleh AA. Effect of Ginger, Curcumin and Their Mixture on Blood Glucose and Lipids in Diabetic Rats. J Life Sci 2013; 10: 428-442.
    • (2013) J Life Sci , vol.10 , pp. 428-442
    • Khattab, H.1    Al-Amoudi, N.S.2    Al-Faleh, A.A.3
  • 27
    • 79551634266 scopus 로고    scopus 로고
    • Effects of Aqueous Extract of Spices Mixture Containing Curry, Garlic and Ginger on Plasma Glucose and Lipids in Alloxan-induced Diabetic Rats
    • Ugwuja EI, Nwibo AN, Ugwu NC, Aloke C. Effects of Aqueous Extract of Spices Mixture Containing Curry, Garlic and Ginger on Plasma Glucose and Lipids in Alloxan-induced Diabetic Rats. Pak J Nutri 2010; 9: 1131-1135.
    • (2010) Pak J Nutri , vol.9 , pp. 1131-1135
    • Ugwuja, E.I.1    Nwibo, A.N.2    Ugwu, N.C.3    Aloke, C.4
  • 28
    • 84979675423 scopus 로고    scopus 로고
    • To Establish the Effect of Ginger-Juice Zingiber Officinale (Zingiberaceae) on Important Parameters of Lipid Profile
    • Prasad SS, Kumar S, Vajpeyee SK, Bhavsar VH. To Establish the Effect of Ginger-Juice Zingiber Officinale (Zingiberaceae) on Important Parameters of Lipid Profile. Int J Pharma Sci Res 2012; 3: 352-356.
    • (2012) Int J Pharma Sci Res , vol.3 , pp. 352-356
    • Prasad, S.S.1    Kumar, S.2    Vajpeyee, S.K.3    Bhavsar, V.H.4
  • 29
    • 70449635105 scopus 로고    scopus 로고
    • The effect of total extract of Securigera securidaca L. Seeds on serum lipid profiles, antioxidant status, and vascular function in hypercholesterolemic rats
    • Garjani A, Fathiazad F, Zakheri A, Akbari NA, Azarmie Y. The effect of total extract of Securigera securidaca L. seeds on serum lipid profiles, antioxidant status, and vascular function in hypercholesterolemic rats. J Ethnopharmacol 2009; 126: 525-532.
    • (2009) J Ethnopharmacol , vol.126 , pp. 525-532
    • Garjani, A.1    Fathiazad, F.2    Zakheri, A.3    Akbari, N.A.4    Azarmie, Y.5
  • 30
    • 0034284704 scopus 로고    scopus 로고
    • Effects of Momordica charantia powder on serum glucose levels and various lipid parameters in rats fed with cholesterol-free and cholesterolenriched diets
    • Jayasooriya AP, Sakono M, Yukizaki C, Kawano M, Yamamoto K, Fukuda N. Effects of Momordica charantia powder on serum glucose levels and various lipid parameters in rats fed with cholesterol-free and cholesterolenriched diets. J Ethnopharmacol 2000; 72: 331-336.
    • (2000) J Ethnopharmacol , vol.72 , pp. 331-336
    • Jayasooriya, A.P.1    Sakono, M.2    Yukizaki, C.3    Kawano, M.4    Yamamoto, K.5    Fukuda, N.6
  • 31
    • 84871351977 scopus 로고    scopus 로고
    • Hepatoprotective and Hypolipidemic Effects of Satureja Khuzestanica Essential Oil in Alloxan-induced Type 1 Diabetic Rats
    • Ahmadvanda H, Tavafic M, Khalatbary AR. Hepatoprotective and Hypolipidemic Effects of Satureja Khuzestanica Essential Oil in Alloxan-induced Type 1 Diabetic Rats. Iran J Pharma Res 2012; 11: 1219-1226.
    • (2012) Iran J Pharma Res , vol.11 , pp. 1219-1226
    • Ahmadvanda, H.1    Tavafic, M.2    Khalatbary, A.R.3
  • 32
    • 85091130454 scopus 로고    scopus 로고
    • Effect of Ginger Extract Consumption on levels of blood Glucose, Lipid Profile and Kidney Functions in Alloxan Induced-Diabetic Rats
    • Abd-Elraheem AE, Salman MMA, Mahrous MA, Moussa MMA. Effect of Ginger Extract Consumption on levels of blood Glucose, Lipid Profile and Kidney Functions in Alloxan Induced-Diabetic Rats. Egypt Acad J biolog Sci 2009; 2: 153-162.
    • (2009) Egypt Acad J Biolog Sci , vol.2 , pp. 153-162
    • Abd-Elraheem, A.E.1    Salman, M.2    Mahrous, M.A.3    Moussa, M.M.A.4
  • 33
    • 1042292667 scopus 로고    scopus 로고
    • Anti-diabetic activity of Zingiber officinale in streptozotocin-induced type I diabetic rats
    • Akhani SP, Vishwarkarma SL, Goval RK. Anti-diabetic activity of Zingiber officinale in streptozotocin-induced type I diabetic rats. J Pharm Pharmacol 2004; 56: 101-105.
    • (2004) J Pharm Pharmacol , vol.56 , pp. 101-105
    • Akhani, S.P.1    Vishwarkarma, S.L.2    Goval, R.K.3
  • 34
    • 79955606502 scopus 로고    scopus 로고
    • Evaluation of the Activity of Zingiber officinale (Ginger) Aqueous Extraction on Alloxan-Induced Diabetic Rats
    • Ozougwu JC, Eyo JE. Evaluation of the Activity of Zingiber officinale (Ginger) Aqueous Extraction on Alloxan-Induced Diabetic Rats. Pharmacologyonline 2011; 1: 258-269.
    • (2011) Pharmacologyonline , vol.1 , pp. 258-269
    • Ozougwu, J.C.1    Eyo, J.E.2
  • 35
    • 0346100456 scopus 로고    scopus 로고
    • In vitro influence of spices and spice-active principles on digestive enzymes of rat pancreas and small intestine
    • Ramakrishna RR, Platel K, Srinivasan K. In vitro influence of spices and spice-active principles on digestive enzymes of rat pancreas and small intestine. Nahrung 2003; 47: 408-412.
    • (2003) Nahrung , vol.47 , pp. 408-412
    • Ramakrishna, R.R.1    Platel, K.2    Srinivasan, K.3
  • 36
    • 3042849117 scopus 로고    scopus 로고
    • Protective effect of ginger, Zingiber officinale Rosc on experimental atherosclerosis in rabbits
    • Verma SK, Singh M, Jain P, Bordia A. Protective effect of ginger, Zingiber officinale Rosc on experimental atherosclerosis in rabbits. Indian J Exp Biol 2004; 42: 736-738.
    • (2004) Indian J Exp Biol , vol.42 , pp. 736-738
    • Verma, S.K.1    Singh, M.2    Jain, P.3    Bordia, A.4
  • 37
    • 84885930514 scopus 로고    scopus 로고
    • Histological studies on pancreatic tissue in diabetic rats by using wild cherry
    • Qadori YT. Histological studies on pancreatic tissue in diabetic rats by using wild cherry. The Iraqi Postgra Med J 2011; 10: 421-425.
    • (2011) The Iraqi Postgra Med J , vol.10 , pp. 421-425
    • Qadori, Y.T.1
  • 38
    • 84929206624 scopus 로고    scopus 로고
    • Impact of streptozotocin on altering normal glucose homeostasis during insulin testing in diabetic rats compared to normoglycemic rats
    • Qinna NA, Badwan AA. Impact of streptozotocin on altering normal glucose homeostasis during insulin testing in diabetic rats compared to normoglycemic rats. Drug Design Devel Therapy 2015; 9: 2515-2525.
    • (2015) Drug Design Devel Therapy , vol.9 , pp. 2515-2525
    • Qinna, N.A.1    Badwan, A.A.2
  • 39
    • 77955633792 scopus 로고    scopus 로고
    • Targeting inflammation induced obesity and metabolic diseases by curcumin and other nutraceuticals
    • Aggarwal BB. Targeting inflammation induced obesity and metabolic diseases by curcumin and other nutraceuticals. Annu Rev Nutri 2010; 30: 173-199.
    • (2010) Annu Rev Nutri , vol.30 , pp. 173-199
    • Aggarwal, B.B.1
  • 40
    • 84856560488 scopus 로고    scopus 로고
    • [6]-Gingerol isolated from ginger attenuates sodium arsenite induced oxidative stress and plays a corrective role in improving insulin signaling in mice
    • Chakraborty D, Mukherjee A, Sikdar S, Paul A, Ghosh S, Khuda-Bukhsh AR.[6]-Gingerol isolated from ginger attenuates sodium arsenite induced oxidative stress and plays a corrective role in improving insulin signaling in mice. Toxicolo Letters 2012; 210: 34-43.
    • (2012) Toxicolo Letters , vol.210 , pp. 34-43
    • Chakraborty, D.1    Mukherjee, A.2    Sikdar, S.3    Paul, A.4    Ghosh, S.5    Khuda-Bukhsh, A.R.6
  • 41
    • 0348090547 scopus 로고    scopus 로고
    • Antitubercular potential of selected plant materials
    • Usha K, Saroja S. Antitubercular potential of selected plant materials. J Med Arom Plant Sci 2000; 22: 182-184.
    • (2000) J Med Arom Plant Sci , vol.22 , pp. 182-184
    • Usha, K.1    Saroja, S.2
  • 42
    • 13544263392 scopus 로고    scopus 로고
    • Effect of ethanolic extract of Zingiber officinal on dyslipidemia in diabetic
    • Bhandari U, Kanojia R, Pillai KK. Effect of ethanolic extract of Zingiber officinal on dyslipidemia in diabetic. J Ethnophar Macol 2005; 97: 227-230.
    • (2005) J Ethnophar Macol , vol.97 , pp. 227-230
    • Bhandari, U.1    Kanojia, R.2    Pillai, K.K.3
  • 43
    • 79960082627 scopus 로고    scopus 로고
    • Animals models for studying diabetes mellitus
    • Etuk EU. Animals models for studying diabetes mellitus. Agri Biol J North Am 2010; 1: 130-134.
    • (2010) Agri Biol J North Am , vol.1 , pp. 130-134
    • Etuk, E.U.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.