RBM3 regulates temperature sensitive miR-142-5p and miR-143 (thermomiRs), which target immune genes and control fever

Nucleic Acids Research

Volumn 44, Issue 6, 2016, Pages 2888-2897

  Wong, Justin J L ^a,b   Au, Amy Y M ^a,b   Gao, Dadi ^a,b   Pinello, Natalia ^a,b   Kwok, Chau To ^a,b   Thoeng, Annora ^a,b   Lau, Katherine A ^a,b   Gordon, Jane E A ^a,b   Schmitz, Ulf ^a,b   Feng, Yue ^a,b   Nguyen, Trung V ^a,b   Middleton, Robert ^a,b   Bailey, Charles G ^a,b   Holst, Jeff ^a,b   Rasko, John E J ^a,b,c   Ritchie, William ^a,b,d  

^a CENTENARY INSTITUTE   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^d INSTITUT DE GÉNOMIQUE FONCTIONNELLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; MICRORNA; MICRORNA 142 5P; MICRORNA 143; PROSTAGLANDIN E2; REGULATOR PROTEIN; RNA BINDING MOTIF PROTEIN 3; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; GLYCOPROTEIN GP 130; IL6 PROTEIN, HUMAN; IL6ST PROTEIN, HUMAN; MIRN142 MICRORNA, HUMAN; MIRN143 MICRORNA, HUMAN; PROSTAGLANDIN E RECEPTOR; RBM3 PROTEIN, HUMAN; RNA BINDING PROTEIN; SMALL INTERFERING RNA; TLR2 PROTEIN, HUMAN; TNF PROTEIN, HUMAN;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE CONTROL; FEVER; GENE TARGETING; HUMAN; HUMAN CELL; IL 6 GENE; IL6ST GENE; IMMUNE RESPONSE GENE; MACROPHAGE; NEGATIVE FEEDBACK; PERIPHERAL BLOOD MONONUCLEAR CELL; PGE2 GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; THERMOREGULATION; TLR2 GENE; TNF GENE; ANTAGONISTS AND INHIBITORS; BODY TEMPERATURE; CELL LINE; CYTOLOGY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; MONONUCLEAR CELL; PATHOLOGY; PHYSIOLOGICAL FEEDBACK; PRIMARY CELL CULTURE; SIGNAL TRANSDUCTION;

BODY TEMPERATURE; BODY TEMPERATURE REGULATION; CELL LINE; CYTOKINE RECEPTOR GP130; FEEDBACK, PHYSIOLOGICAL; FEVER; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-6; LEUKOCYTES, MONONUCLEAR; MACROPHAGES; MICRORNAS; PRIMARY CELL CULTURE; RECEPTORS, PROSTAGLANDIN E; RNA, SMALL INTERFERING; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84963812275     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkw041     Document Type: Article

References (51)

1. Leon, L.R. (2002) Invited review: cytokine regulation of fever: studies using gene knockout mice. J. Appl. Physiol., 92, 2648-2655.
2. Ogoina, D. (2011) Fever, fever patterns and diseases called 'fever'-a review. J. Infect. Public Health, 4, 108-124.
3. Greer, D.M., Funk, S.E., Reaven, N.L., Ouzounelli, M. and Uman, G.C. (2008) Impact of fever on outcome in patients with stroke and neurologic injury: a comprehensive meta-analysis. Stroke, 39, 3029-3035.
4. Young, P., Saxena, M., Beasley, R., Bellomo, R., Bailey, M., Pilcher, D., Finfer, S., Harrison, D., Myburgh, J. and Rowan, K. (2012) Early peak temperature and mortality in critically ill patients with or without infection. Intensive Care Med., 38, 437-444.
5. Wilczynska, A. and Bushell, M. (2015) The complexity of miRNA-mediated repression. Cell Death Differ., 22, 22-33.
6. Lai, E.C. (2002) Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation. Nat. Genet., 30, 363-364.
7. Vidigal, J.A. and Ventura, A. (2015) The biological functions of miRNAs: lessons from in vivo studies. Trends Cell Biol., 25, 137-147.
8. Li, Y. and Kowdley, K.V. (2012) MicroRNAs in common human diseases. Genomics Proteomics Bioinformatics, 10, 246-253.
9. Ma, Y., Vilanova, D., Atalar, K., Delfour, O., Edgeworth, J., Ostermann, M., Hernandez-Fuentes, M., Razafimahatratra, S., Michot, B., Persing, D.H. et al. (2013) Genome-wide sequencing of cellular microRNAs identifies a combinatorial expression signature diagnostic of sepsis. PLoS One, 8, e75918.
10. Maslove, D.M. and Wong, H.R. (2014) Gene expression profiling in sepsis: timing, tissue, and translational considerations. Trends Mol. Med., 20, 204-213.
11. Schnoor, M., Buers, I., Sietmann, A., Brodde, M.F., Hofnagel, O., Robenek, H. and Lorkowski, S. (2009) Efficient non-viral transfection of THP-1 cells. J. Immunol. Methods, 344, 109-115.
12. Langmead, B. and Salzberg, S.L. (2012) Fast gapped-read alignment with Bowtie 2. Nat. Methods, 9, 357-359.
13. Ritchie, W., Gao, D. and Rasko, J.E. (2012) Defining and providing robust controls for microRNA prediction. Bioinformatics, 28, 1058-1061.
14. Vermeulen, A., Robertson, B., Dalby, A.B., Marshall, W.S., Karpilow, J., Leake, D., Khvorova, A. and Baskerville, S. (2007) Double-stranded regions are essential design components of potent inhibitors of RISC function. RNA, 13, 723-730.
15. Dudoit, S., Yang, Y.H., Callow, M.J. and Speed, T.P. (2002) Statistical methods for identifying differentially expressed genes in replicated cDNA microarray experiments. Stat. Sinica, 12, 111-139.
16. Wong, J., Ritchie, W., Gao, D., Lau, K., Gonzalez, M., Choudhary, A., Taft, R., Rasko, J. and Holst, J. (2014) Identification of nuclear-enriched miRNAs during mouse granulopoiesis. J. Hematol. Oncol., 7, 42.
17. Huang, D.W., Sherman, B.T. and Lempicki, R.A. (2008) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc., 4, 44-57.
18. Hu, X., Yu, J., Crosby, S.D. and Storch, G.A. (2013) Gene expression profiles in febrile children with defined viral and bacterial infection. Proc. Natl. Acad. Sci. U. S. A., 110, 12792-12797.
19. Mancardi, D.A., Albanesi, M., Jönsson, F., Iannascoli, B., Van Rooijen, N., Kang, X., England, P., Däeron, M. and Bruhns, P. (2013) The high-affinity human IgG receptor FcγRI (CD64) promotes IgG-mediated inflammation, anaphylaxis, and antitumor immunotherapy. Blood, 121, 1563-1573.
20. Neote, K., DiGregorio, D., Mak, J.Y., Horuk, R. and Schall, T.J. (1993) Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor. Cell, 72, 415-425.
21. Hayashi, F., Smith, K.D., Ozinsky, A., Hawn, T.R., Yi, E.C., Goodlett, D.R., Eng, J.K., Akira, S., Underhill, D.M. and Aderem, A. (2001) The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature, 410, 1099-1103.
22. Takeuchi, O., Kawai, T., Sanjo, H., Copeland, N.G., Gilbert, D.J., Jenkins, N.A., Takeda, K. and Akira, S. (1999) TLR6: A novel member of an expanding Toll-like receptor family. Gene, 231, 59-65.
23. Moore, P.A., Belvedere, O., Orr, A., Pieri, K., LaFleur, D.W., Feng, P., Soppet, D., Charters, M., Gentz, R., Parmelee, D. et al. (1999) BLyS: Member of the tumor necrosis factor family and B lymphocyte stimulator. Science, 285, 260-263.
24. Dinarello, C.A. (2011) Interleukin-1 in the pathogenesis and treatment of inflammatory diseases. Blood, 117, 3720-3732.
25. Yost, H.J. and Lindquist, S. (1986) RNA splicing is interrupted by heat shock and is rescued by heat shock protein synthesis. Cell, 45, 185-193.
26. Bell, J., Neilson, L. and Pellegrini, M. (1988) Effect of heat shock on ribosome synthesis in Drosophila melanogaster. Mol. Cell Biol., 8, 91-95.
27. Shalgi, R., Hurt, J.A., Lindquist, S. and Burge, C.B. (2014) Widespread inhibition of posttranscriptional splicing shapes the cellular transcriptome following heat shock. Cell Rep., 7, 1362-1370.
28. Dresios, J., Aschrafi, A., Owens, G.C., Vanderklish, P.W., Edelman, G.M. and Mauro, V.P. (2005) Cold stress-induced protein Rbm3 binds 60S ribosomal subunits, alters microRNA levels, and enhances global protein synthesis. Proc. Natl. Acad. Sci. U. S. A., 102, 1865-1870.
29. Pilotte, J., Dupont-Versteegden, E.E. and Vanderklish, P.W. (2011) Widespread regulation of miRNA biogenesis at the Dicer step by the cold-inducible RNA-binding protein, RBM3. PLoS One, 6, e28446.
30. Chanput, W., Mes, J.J. and Wichers, H.J. (2014) THP-1 cell line: An in vitro cell model for immune modulation approach. Int. Immunopharmacol., 23, 37-45.
31. Roger, T., Lugrin, J., Le Roy, D., Goy, G., Mombelli, M., Koessler, T., Ding, X.C., Chanson, A.L., Reymond, M.K., Miconnet, I. et al. (2011) Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection. Blood, 117, 1205-1217.
32. Kelada, S., Sethupathy, P., Okoye, I.S., Kistasis, E., Czieso, S., White, S.D., Chou, D., Martens, C., Ricklefs, S.M., Virtaneva, K. et al. (2013) miR-182 and miR-10a are key regulators of Treg specialisation and stability during Schistosome and Leishmania-associated inflammation. PLoS Pathog., 9, e1003451.
33. Chen, T., Huang, Z., Wang, L., Wang, Y., Wu, F., Meng, S. and Wang, C. (2009) MicroRNA-125a-5p partly regulates the inflammatory response, lipid uptake, and ORP9 expression in oxLDL-stimulated monocyte/macrophages. Cardiovasc. Res., 83, 131-139.
34. Ceribelli, A., Yao, B., Dominguez-Gutierrez, P.R., Nahid, M.A., Satoh, M. and Chan, E.K. (2011) MicroRNAs in systemic rheumatic diseases. Arthritis Res. Ther., 13, 229.
35. Ding, S., Liang, Y., Zhao, M., Liang, G., Long, H., Zhao, S., Wang, Y., Yin, H., Zhang, P., Zhang, Q. et al. (2012) Decreased microRNA-142-3p/5p expression causes CD4+ T cell activation and B cell hyperstimulation in systemic lupus erythematosus. Arthritis Rheum., 64, 2953-2963.
36. Guo, H., Chen, Y., Hu, X., Qian, G., Ge, S. and Zhang, J. (2013) The regulation of Toll-like receptor 2 by miR-143 suppresses the invasion and migration of a subset of human colorectal carcinoma cells. Mol. Cancer, 12, 77.
37. Ehlen, A., Brennan, D., Nodin, B., O'Connor, D., Eberhard, J., Alvarado-Kristensson, M., Jeffrey, I., Manjer, J., Brandstedt, J., Uhlen, M. et al. (2010) Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer. J. Transl. Med., 8, 78.
38. Pham, H., Rodriguez, C.E., Donald, G.W., Hertzer, K.M., Jung, X.S., Chang, H.H., Moro, A., Reber, H.A., Hines, O.J. and Eibl, G. (2013) miR-143 decreases COX-2 mRNA stability and expression in pancreatic cancer cells. Biochem. Biophys. Res. Commun., 439, 6-11.
39. Sun, Y., Varambally, S., Maher, C.A., Cao, Q., Chockley, P., Toubai, T., Malter, C., Nieves, E., Tawara, I., Wang, Y. et al. (2011) Targeting of microRNA-142-3p in dendritic cells regulates endotoxin-induced mortality. Blood, 117, 6172-6183.
40. Sharma, S., Liu, J., Wei, J., Yuan, H., Zhang, T. and Bishopric, N.H. (2012) Repression of miR-142 by p300 and MAPK is required for survival signalling via gp130 during adaptive hypertrophy. EMBO Mol. Med., 4, 617-632.
41. Dinarello, C.A. (2004) Infection, fever, and exogenous and endogenous pyrogens: some concepts have changed. J. Endotoxin Res., 10, 201-222.
42. Bernheim, H.A. and Kluger, M.J. (1976) Fever and antipyresis in the lizard Dipsosaurus dorsalis. Am. J. Physiol., 231, 198-203.
43. Rottiers, V. and Naar, A.M. (2012) MicroRNAs in metabolism and metabolic disorders. Nat. Rev. Mol. Cell Biol., 13, 239-250.
44. Roderburg, C., Luedde, M., Vargas Cardenas, D., Vucur, M., Scholten, D., Frey, N., Koch, A., Trautwein, C., Tacke, F. and Luedde, T. (2013) Circulating microRNA-150 serum levels predict survival in patients with critical illness and sepsis. PLoS One, 8, e54612.
45. Liu, Y., Hu, W., Murakawa, Y., Yin, J., Wang, G., Landthaler, M. and Yan, J. (2013) Cold-induced RNA-binding proteins regulate circadian gene expression by controlling alternative polyadenylation. Sci. Rep., 3, 2054.
46. Na, Y.-J., Sung, J.H., Lee, S.C., Lee, Y.-J., Choi, Y.J., Park, W.-Y., Shin, H.S. and Kim, J.H. (2009) Comprehensive analysis of microRNA-mRNA co-expression in circadian rhythm. Exp. Mol. Med., 41, 638-647.
47. Corry, J.J. (2012) Use of hypothermia in the intensive care unit. World J. Crit. Care Med., 1, 106-122.
48. Gouel-Cheron, A., Allaouchiche, B., Guignant, C., Davin, F., Floccard, B., Monneret, G. and AzuRea, G. (2012) Early interleukin-6 and slope of monocyte human leukocyte antigen-DR: a powerful association to predict the development of sepsis after major trauma. PLoS One, 7, e33095.
49. Rybka, J., Butrym, A., Wrobel, T., Jazwiec, B., Stefanko, E., Dobrzynska, O., Poreba, R. and Kuliczkowski, K. (2014) The expression of Toll-like receptors and development of severe sepsis in patients with acute myeloid leukemias after induction chemotherapy. Med. Oncol., 31, 319.
50. Brogliato, A.R., Antunes, C.A., Carvalho, R.S., Monteiro, A.P., Tinoco, R.F., Bozza, M.T., Canetti, C., Peters-Golden, M., Kunkel, S.L., Vianna-Jorge, R. et al. (2012) Ketoprofen impairs immunosuppression induced by severe sepsis and reveals an important role for prostaglandin E2. Shock, 38, 620-629.
51. Lv, S., Han, M., Yi, R., Kwon, S., Dai, C. and Wang, R. (2014) Anti-TNF-alpha therapy for patients with sepsis: a systematic meta-analysis. Int. J. Clin. Pract., 68, 520-528.