MiR-143 decreases COX-2 mRNA stability and expression in pancreatic cancer cells

Biochemical and Biophysical Research Communications

Volumn 439, Issue 1, 2013, Pages 6-11

  Pham, Hung ^a,b   Ekaterina Rodriguez, C ^a   Donald, Graham W ^a   Hertzer, Kathleen M ^a   Jung, Xiaoman S ^a   Chang, Hui Hua ^a   Moro, Aune ^a   Reber, Howard A ^a   Hines, O Joe ^a   Eibl, Guido ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

Author keywords

Cyclooxygenase 2; MAPK; MiR 143; Pancreatic cancer; Prostaglandin E2

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CYCLOOXYGENASE 2; MICRORNA 143; MITOGEN ACTIVATED PROTEIN KINASE; PROSTAGLANDIN E2;

ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HUMAN TISSUE; METASTASIS; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION;

3-(4,5-DIMETHYLTHIAZOL-2-YL)-2,5-DIPHENYLTETRAZOLIUM BROMIDE; COX-2; CREB; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLOOXYGENASE-2; MAPK; MAPK KINASE; MEK; MICRORNA-143; MIR-143; MITOGEN-ACTIVATED PROTEIN KINASE; MTT; PACA; PANCREATIC CANCER; PGE(2); PKA; PROSTAGLANDIN E(2); PROTEIN KINASE A; RAS RESPONSIVE ELEMENT BINDING PROTEIN; RREB1;

BUTADIENES; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLOOXYGENASE 2; DINOPROSTONE; DNA-BINDING PROTEINS; ENZYME INHIBITORS; FLAVONOIDS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MAP KINASE KINASE KINASES; MICRORNAS; NITRILES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PANCREATIC NEOPLASMS; RNA STABILITY; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTION FACTORS;

AGOUTI PACA;

EID: 84883753319     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.08.042     Document Type: Article

References (38)

1. Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116:281-297.
2. Bushati N., Cohen S.M. MicroRNA functions. Ann. Rev. Cell Dev. Biol. 2007, 23:175-205.
3. Krol J., Loedige I., Filipowicz W. The widespread regulation of microRNA biogenesis, function and decay. Nat. Rev. Genet. 2010, 11:597-610.
4. Singh P.K., Brand R.E., Mehla K. MicroRNAs in pancreatic cancer metabolism. Nat. Rev. Gastroenterol. Hepatol. 2012, 9(6):334-344.
5. Esquela-Kerscher A., Slack F.J. Oncomirs-microRNAs with a role in cancer. Nat. Rev. Cancer 2006, 6(4):259-269.
6. He X.P., Shao Y., Li X.L., Xu W., Chen G.S., Sun H.H., Xu H.C., Xu X., Tang D., Zheng X.F., Xue Y.P., Huang G.C., Sun W.H. Downregulation of miR-101 in gastric cancer correlates with cyclooxygenase-2 overexpression and tumor growth. FEBS J. 2012, 279(22):4201-4212.
7. Strillacci A., Griffoni C., Sansone P., Paterini P., Piazzi G., Lazzarini G., Spisni E., Pantaleo M.A., Biasco G., Tomasi V. MiR-101 downregulation is involved in cyclooxygenase-2 overexpression in human colon cancer cells. Exp. Cell Res. 2009, 315(8):1439-1447.
8. Rouzer C.A., Marnett L.J. Cyclooxygenases: structural and functional insights. J. Lipid Res. 2009, 50(Suppl.):S29-S34.
9. 2 in inflammation and cancer. Semin. Immunopathol. 2013, 35(2):123-137.
10. 2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment. Carcinogenesis 2009, 30(3):377-386.
11. Wang M.T., Honn K.V., Nie D. Cyclooxygenases, prostanoids, and tumor progression. Cancer Metastasis Rev. 2007, 26(3-4):525-534.
12. 2 drives cyclooxygenase-2 expression via cyclic AMP response element activation in human pancreatic cancer cells. Cancer Biol. Ther. 2005, 4(11):1263-1269.
13. Moore A.E., Young L.E., Dixon D.A. A common single-nucleotide polymorphism in cyclooxygenase-2 disrupts microRNA-mediated regulation. Oncogene 2012, 31(12):1592-1598.
14. Lin T., Dong W., Huang J., Pan Q., Fan X., Zhang C., Huang L. MicroRNA-143 as a tumor suppressor for bladder cancer. J. Urol. 2009, 181(3):1372-1380.
15. Noguchi S., Mori T., Hoshino Y., Maruo K., Yamada N., Kitade Y., Naoe T., Akao Y. MicroRNA-143 functions as a tumor suppressor in human bladder cancer T24 cells. Cancer Lett. 2011, 307(2):211-220.
16. Takahashi H., Li A., Dawson D.W., Hines O.J., Reber H.A., Eibl G. Cyclooxygenase-2 confers growth advantage to syngeneic pancreatic cancer cells. Pancreas 2011, 40(3):453-459.
17. 2 in pancreatic tumors. Pancreas 2010, 39(3):332-339.
18. Collins M.A., Bednar F., Zhang Y., Brisset J.C., Galban S., Galban C.J., Rakshit S., Flannagan K.S., Adsay N.V., Pasca di Magliano M. Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice. J. Clin. Invest. 2012, 122(2):639-653.
19. Chen X., Guo X., Zhang H., Xiang Y., Chen J., Yin Y., Cai X., Wang K., Wang G., Ba Y., Zhu L., Wang J., Yang R., Zhang Y., Ren Z., Zen K., Zhang J., Zhang C.Y. Role of miR-143 targeting KRAS in colorectal tumorigenesis. Oncogene 2009, 28(10):1385-1392.
20. Kent O.A., Chivukula R.R., Mullendore M., Wentzel E.A., Feldmann G., Lee K.H., Liu S., Leach S.D., Maitra A., Mendell J.T. Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway. Genes Dev. 2010, 24(24):2754-2759.
21. Kent O.A., Fox-Talbot K., Halushka M.K. RREB1 repressed miR-143/145 modulates KRAS signaling through downregulation of multiple targets. Oncogene 2013, 32(20):2576-2585.
22. 2/cAMP-dependent viral replication in human neuroblastoma cells: role of the c-Src/EGFR/p42/p44 MAPK/CREB signaling pathway. J. Cell Biochem. 2011, 112(2):559-570.
23. Hu Y., Ou Y., Wu K., Chen Y., Sun W. MiR-143 inhibits the metastasis of pancreatic cancer and an associated signaling pathway. Tumour Biol. 2012, 33(6):1863-1870.
24. Akao Y., Nakagawa Y., Naoe T. MicroRNA-143 and -145 in colon cancer. DNA Cell Biol. 2007, 26(5):311-320.
25. Navarrete C.M., Perez M., de Vinuesa A.G., Collado J.A., Fiebich B.L., Calzado M.A., Munoz E. Endogenous N-acyl-dopamines induce COX-2 expression in brain endothelial cells by stabilizing mRNA through a p38 dependent pathway. Biochem. Pharmacol. 2010, 79(12):1805-1814.
26. Chang M.S., Chen B.C., Weng C.M., Lee W.S., Lin C.H. Involvement of Ras/Raf-1/p44/42 MAPK in YC-1-induced cyclooxygenase-2 expression in human pulmonary epithelial cells. Pharmacol. Res. 2009, 60(4):247-253.
27. Zhang X., Zhang J., Yang X., Han X. Several transcription factors regulate COX-2 gene expression in pancreatic beta-cells. Mol. Biol. Rep. 2007, 34(3):199-206.
28. Lasa M., Mahtani K.R., Finch A., Brewer G., Saklatvala J., Clark A.R. Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade. Mol. Cell. Biol. 2000, 20(12):4265-4274.
29. Cok S.J., Acton S.J., Morrison A.R. The proximal region of the 3'-untranslated region of cyclooxygenase-2 is recognized by a multimeric protein complex containing HuR, TIA-1, TIAR, and the heterogeneous nuclear ribonucleoprotein U. J. Biol. Chem. 2003, 278(38):36157-36162.
30. Young L.E., Moore A.E., Sokol L., Meisner-Kober N., Dixon D.A. The mRNA stability factor HuR inhibits microRNA-16 targeting of COX-2. Mol. Cancer Res. 2012, 10(1):167-180.
31. Vlachos I.S., Kostoulas N., Vergoulis T., Georgakilas G., Reczko M., Maragkakis M., Paraskevopoulou M.D., Prionidis K., Dalamagas T., Hatzigeorgiou A.G. DIANA miRPath v. 2.0: investigating the combinatorial effect of microRNAs in pathways. Nucleic Acids Res. 2012, 40:W498-W504.
32. Yang Y., Chaerkady R., Kandasamy K., Huang T.C., Selvan L.D., Dwivedi S.B., Kent O.A., Mendell J.T., Pandey A. Identifying targets of miR-143 using a SILAC-based proteomic approach. Mol. Biosyst. 2010, 6(10):1873-1882.
33. Clape C., Fritz V., Henriquet C., Apparailly F., Fernandez P.L., Iborra F., Avances C., Villalba M., Culine S., Fajas L. MiR-143 interferes with ERK5 signaling, and abrogates prostate cancer progression in mice. PLoS One 2009, 4(10):e7542.
34. Castellano E., Santos E. Functional specificity of ras isoforms: so similar but so different. Genes Cancer 2011, 2(3):216-231.
35. Campbell P.M., Groehler A.L., Lee K.M., Ouellette M.M., Khazak V., Der C.J. K-Ras promotes growth transformation and invasion of immortalized human pancreatic cells by Raf and phosphatidylinositol 3-kinase signaling. Cancer Res. 2007, 67(5):2098-2106.
36. Costello L.C., Levy B.A., Desouki M.M., Zou J., Bagasra O., Johnson L.A., Hanna N., Franklin R.B. Decreased zinc and downregulation of ZIP3 zinc uptake transporter in the development of pancreatic adenocarcinoma. Cancer Biol. Ther. 2011, 12(4):297-303.
37. Gao J.S., Zhang Y., Tang X., Tucker L.D., Tarwater P.M., Quesenberry P.J., Rigoutsos I., Ramratnam B. The Evi1, microRNA-143, K-Ras axis in colon cancer. FEBS Lett. 2011, 585(4):693-699.
38. Akao Y., Nakagawa Y., Hirata I., Iio A., Itoh T., Kojima K., Nakashima R., Kitade Y., Naoe T. Role of anti-oncomirs miR-143 and -145 in human colorectal tumors. Cancer Gene Ther. 2010, 17(6):398-408.