Proinflammatory effects of pyrogenic and precipitated amorphous silica nanoparticles in innate immunity cells

Toxicological Sciences

Volumn 150, Issue 1, 2016, Pages 40-53

  Di Cristo, Luisana ^a,b   Movia, Dania ^b,c   Bianchi, Massimiliano G ^a   Allegri, Manfredi ^a   Mohamed, Bashir M ^b   Bell, Alan P ^c   Moore, Caroline ^b   Pinelli, Silvana ^a   Rasmussen, Kirsten ^d   Riego Sintes, Juan ^d   Prina Mello, Adriele ^b,c   Bussolati, Ovidio ^a   Bergamaschi, Enrico ^a  

^a UNIVERSITY OF PARMA   (Italy)

^b TRINITY COLLEGE DUBLIN   (Ireland)

^c TRINITY COLLEGE DUBLIN   (Ireland)

^d JOINT RESEARCH CENTRE   (Italy)

Author keywords

Amorphous silica nanoparticles; Food additive; Inflammation; Macrophages; Oxidative stress; Protein corona

Indexed keywords

AMORPHOUS SILICA NANOPARTICLE; BACTERIUM LIPOPOLYSACCHARIDE; HEME OXYGENASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; NITRIC OXIDE; NM 200; NM 203; PLASMA PROTEIN; PYROGEN; REACTIVE OXYGEN METABOLITE; SILICA NANOPARTICLE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CYTOKINE; NANOPARTICLE; SILICON DIOXIDE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; FLOW CYTOMETRY; HELIUM ION MICROSCOPY; HYDRODYNAMICS BASED TRANSFECTION; IMMUNOTOXICITY; INFLAMMATION; INNATE IMMUNITY; INTERNALIZATION; MACROPHAGE; MACROPHAGE ACTIVATION; MOLECULAR INTERACTION; MOUSE; NANOTOXICOLOGY; NONHUMAN; OXIDATIVE STRESS; PARTICLE SIZE; PRECIPITATION; PROTEIN BINDING; SURFACE AREA; SURFACE CHARGE; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; BIOSYNTHESIS; CELL CULTURE TECHNIQUE; CELL LINE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; GENETICS; IMMUNOLOGY; LUNG ALVEOLUS MACROPHAGE; METABOLISM; NANOTECHNOLOGY; PROCEDURES; SECRETION (PROCESS); SURFACE PROPERTY;

ANIMALS; CELL CULTURE TECHNIQUES; CELL LINE; CHEMICAL PRECIPITATION; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; IMMUNITY, INNATE; MACROPHAGES, ALVEOLAR; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; NANOTECHNOLOGY; NITRIC OXIDE; REACTIVE OXYGEN SPECIES; SILICON DIOXIDE; SURFACE PROPERTIES;

EID: 84963812037     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfv258     Document Type: Article

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