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Volumn 112, Issue , 2016, Pages 42-53

A case study in flux balance analysis: Lysine, a cephamycin C precursor, can also increase clavulanic acid production

Author keywords

Antibiotic; Filamentous bacteria; Flux balance analysis; Growth kinetics; Lysine; Physiology

Indexed keywords

ANTIBIOTICS; BACTERIA; BIOCHEMISTRY; BIOSYNTHESIS; CARBOXYLIC ACIDS; GROWTH KINETICS; METABOLISM; METABOLITES; PHYSIOLOGY;

EID: 84962911719     PISSN: 1369703X     EISSN: 1873295X     Source Type: Journal    
DOI: 10.1016/j.bej.2016.03.012     Document Type: Article
Times cited : (7)

References (45)
  • 1
    • 0034844144 scopus 로고    scopus 로고
    • Stoichiometric growth model for riboflavin-producing Bacillus subtilis
    • Dauner M., Sauer U. Stoichiometric growth model for riboflavin-producing Bacillus subtilis. Biotechnol. Bioeng. 2001, 76:132-143.
    • (2001) Biotechnol. Bioeng. , vol.76 , pp. 132-143
    • Dauner, M.1    Sauer, U.2
  • 2
    • 0031933027 scopus 로고    scopus 로고
    • Mathematical modeling and analysis in biochemical engineering: past accomplishments and future opportunities
    • Bailey J.E. Mathematical modeling and analysis in biochemical engineering: past accomplishments and future opportunities. Biotechnol. Progr. 1998, 14:8-20.
    • (1998) Biotechnol. Progr. , vol.14 , pp. 8-20
    • Bailey, J.E.1
  • 3
    • 84897093985 scopus 로고    scopus 로고
    • Systems metabolic engineering design: fatty acid production as an emerging case study
    • Tee T.W., Chowdhury A., Maranas C.D., Shanks J.V. Systems metabolic engineering design: fatty acid production as an emerging case study. Biotechnol. Bioeng. 2014, 111:849-857.
    • (2014) Biotechnol. Bioeng. , vol.111 , pp. 849-857
    • Tee, T.W.1    Chowdhury, A.2    Maranas, C.D.3    Shanks, J.V.4
  • 6
    • 0032980845 scopus 로고    scopus 로고
    • Biosynthesis and molecular genetics of cephamycins
    • Liras P. Biosynthesis and molecular genetics of cephamycins. A. Van. Leeuw. J. Microb. 1999, 75:109-124.
    • (1999) A. Van. Leeuw. J. Microb. , vol.75 , pp. 109-124
    • Liras, P.1
  • 7
    • 78650518489 scopus 로고    scopus 로고
    • Optimisation of the glycerol-to-ornithine molar ratio in the feed medium for the continuous production of clavulanic acid by Streptomyces clavuligerus
    • Domingues L.C., Teodoro J.C., Hokka C.O., Badino A.C., Araujo M.L.G. Optimisation of the glycerol-to-ornithine molar ratio in the feed medium for the continuous production of clavulanic acid by Streptomyces clavuligerus. Biochem. Eng. J. 2010, 53:7-11.
    • (2010) Biochem. Eng. J. , vol.53 , pp. 7-11
    • Domingues, L.C.1    Teodoro, J.C.2    Hokka, C.O.3    Badino, A.C.4    Araujo, M.L.G.5
  • 8
    • 84890502007 scopus 로고    scopus 로고
    • Enhancing effect of lysine combined with other compounds on cephamycin C production in Streptomyces clavuligerus
    • Leite C.A., Cavallieri A.P., Araujo M.L. Enhancing effect of lysine combined with other compounds on cephamycin C production in Streptomyces clavuligerus. BMC Microbiol. 2013, 13:296-307.
    • (2013) BMC Microbiol. , vol.13 , pp. 296-307
    • Leite, C.A.1    Cavallieri, A.P.2    Araujo, M.L.3
  • 10
    • 0036889031 scopus 로고    scopus 로고
    • Mutants of Streptomyces clavuligerus with disruptions in different genes for clavulanic acid biosynthesis produce large amounts of holomycin: possible cross-regulation of two unrelated secondary metabolic pathways
    • de la Fuente A., Lorenzana L.M., Martín J.F., Liras P. Mutants of Streptomyces clavuligerus with disruptions in different genes for clavulanic acid biosynthesis produce large amounts of holomycin: possible cross-regulation of two unrelated secondary metabolic pathways. J. Bacterial. 2002, 184:6559-6565.
    • (2002) J. Bacterial. , vol.184 , pp. 6559-6565
    • de la Fuente, A.1    Lorenzana, L.M.2    Martín, J.F.3    Liras, P.4
  • 11
    • 33646041617 scopus 로고    scopus 로고
    • Manipulation of the physiology of clavulanic acid biosynthesis with the aid of metabolic flux analysis
    • Bushell M.E., Kirk S., Zhao H.J., Avignone-Rossa C.A. Manipulation of the physiology of clavulanic acid biosynthesis with the aid of metabolic flux analysis. Enzyme Microb. Technol. 2006, 39:149-157.
    • (2006) Enzyme Microb. Technol. , vol.39 , pp. 149-157
    • Bushell, M.E.1    Kirk, S.2    Zhao, H.J.3    Avignone-Rossa, C.A.4
  • 13
    • 84962884901 scopus 로고    scopus 로고
    • Flux balance analysis in the production of clavulanic acid by Streptomyces clavuligerus
    • Sánchez C., Quintero J.C., Ochoa S. Flux balance analysis in the production of clavulanic acid by Streptomyces clavuligerus. Biotechnol. Progr. 2015, 1:1-11.
    • (2015) Biotechnol. Progr. , vol.1 , pp. 1-11
    • Sánchez, C.1    Quintero, J.C.2    Ochoa, S.3
  • 14
    • 67651083634 scopus 로고    scopus 로고
    • Toward systematic metabolic engineering based on the analysis of metabolic regulation by the integration of different levels of information
    • Kazuyuki S. Toward systematic metabolic engineering based on the analysis of metabolic regulation by the integration of different levels of information. Biochem. Eng. J. 2009, 46:235-251.
    • (2009) Biochem. Eng. J. , vol.46 , pp. 235-251
    • Kazuyuki, S.1
  • 15
    • 34447523907 scopus 로고    scopus 로고
    • Systematic evaluation of objective functions for predicting intracellular fluxes in Escherichia coli
    • Schuetz R., Kuepfer L., Sauer U. Systematic evaluation of objective functions for predicting intracellular fluxes in Escherichia coli. Mol. Syst. Biol. 2007, 3:119-134.
    • (2007) Mol. Syst. Biol. , vol.3 , pp. 119-134
    • Schuetz, R.1    Kuepfer, L.2    Sauer, U.3
  • 17
    • 33847307148 scopus 로고    scopus 로고
    • Bayesian-based selection of metabolic objective functions
    • Knorr A.L., Jain R., Srivastava R. Bayesian-based selection of metabolic objective functions. Bioinformatics 2007, 23:351-357.
    • (2007) Bioinformatics , vol.23 , pp. 351-357
    • Knorr, A.L.1    Jain, R.2    Srivastava, R.3
  • 18
    • 84902969045 scopus 로고    scopus 로고
    • Complementary elementary modes for fast and efficient analysis of metabolic networks
    • Bahadur M.B., Tsuboi R., Kurata H. Complementary elementary modes for fast and efficient analysis of metabolic networks. Biochem. Eng. J. 2014, 90:121-130.
    • (2014) Biochem. Eng. J. , vol.90 , pp. 121-130
    • Bahadur, M.B.1    Tsuboi, R.2    Kurata, H.3
  • 19
    • 0001396406 scopus 로고
    • Clavulanic acid: properties biosynthesis, and fermentation
    • Marcel Dekker, New York, E.J. Vandamme (Ed.)
    • Butterworth D. Clavulanic acid: properties biosynthesis, and fermentation. Biotechnology of Industrial Antibiotics 1984, 3-31. Marcel Dekker, New York. E.J. Vandamme (Ed.).
    • (1984) Biotechnology of Industrial Antibiotics , pp. 3-31
    • Butterworth, D.1
  • 20
    • 0029929181 scopus 로고    scopus 로고
    • Cell density influences antibiotic biosynthesis in Streptomyces clavuligerus
    • Sánchez L., Brana A.F. Cell density influences antibiotic biosynthesis in Streptomyces clavuligerus. Microbiology 1996, 142:1209-1220.
    • (1996) Microbiology , vol.142 , pp. 1209-1220
    • Sánchez, L.1    Brana, A.F.2
  • 22
    • 0020440898 scopus 로고
    • Assay of Amoxicillin and Clavulanic Acid the Components of Augmentin, in biological fluids with high-performance liquid chromatography
    • Foulstone M., Reading C. Assay of Amoxicillin and Clavulanic Acid the Components of Augmentin, in biological fluids with high-performance liquid chromatography. Antimicrob. Agents Ch. 22 1982, 753-762.
    • (1982) Antimicrob. Agents Ch. 22 , pp. 753-762
    • Foulstone, M.1    Reading, C.2
  • 23
    • 0015384891 scopus 로고
    • Determination of protein: a modification of the Lowry method that gives a linear photometric response
    • Hartree E.F. Determination of protein: a modification of the Lowry method that gives a linear photometric response. Anal. Biochem. 1972, 48:422-427.
    • (1972) Anal. Biochem. , vol.48 , pp. 422-427
    • Hartree, E.F.1
  • 24
    • 0000169232 scopus 로고
    • An algorithm for least-squares estimation of nonlinear parameters
    • Marquardt D.W. An algorithm for least-squares estimation of nonlinear parameters. J. Soc. Ind. Appl. Math. 1963, 11:431-441.
    • (1963) J. Soc. Ind. Appl. Math. , vol.11 , pp. 431-441
    • Marquardt, D.W.1
  • 25
    • 0031792986 scopus 로고    scopus 로고
    • Malate synthase from Streptomyces clavuligerus NRRL3585: cloning, molecular characterization and its control by acetate
    • Chan M., Sim T.S. Malate synthase from Streptomyces clavuligerus NRRL3585: cloning, molecular characterization and its control by acetate. Microbiol. 1998, 144:3229-3237.
    • (1998) Microbiol. , vol.144 , pp. 3229-3237
    • Chan, M.1    Sim, T.S.2
  • 26
    • 0035803954 scopus 로고    scopus 로고
    • Cloning heterologous expression and purification of an isocitrate lyase from Streptomyces clavuligerus NRRL 3585
    • Seng S.B., Loke P., Tiow-Suan S. Cloning heterologous expression and purification of an isocitrate lyase from Streptomyces clavuligerus NRRL 3585. BBA-Gene Struct. Expr. 2001, 1522:112-117.
    • (2001) BBA-Gene Struct. Expr. , vol.1522 , pp. 112-117
    • Seng, S.B.1    Loke, P.2    Tiow-Suan, S.3
  • 28
    • 0024486867 scopus 로고
    • Lysine catabolism in Streptomyces spp. is primarily through cadaverine: beta-lactam producers also make alpha-aminoadipate
    • Madduri K., Stuttard C., Vining L.C. Lysine catabolism in Streptomyces spp. is primarily through cadaverine: beta-lactam producers also make alpha-aminoadipate. J. Bacteriol. 1989, 171:299-302.
    • (1989) J. Bacteriol. , vol.171 , pp. 299-302
    • Madduri, K.1    Stuttard, C.2    Vining, L.C.3
  • 30
    • 0029804432 scopus 로고    scopus 로고
    • Growth rate control of protein and nucleic acid content in Streptomyces coelicolor A3 (2) and Escherichia coli B/r
    • Shahab N., Flett F., Oliver S.G., Butler P.R. Growth rate control of protein and nucleic acid content in Streptomyces coelicolor A3 (2) and Escherichia coli B/r. Microbiology 1996, 142:1927-1935.
    • (1996) Microbiology , vol.142 , pp. 1927-1935
    • Shahab, N.1    Flett, F.2    Oliver, S.G.3    Butler, P.R.4
  • 31
    • 0030696204 scopus 로고    scopus 로고
    • Differentiation of Streptomyces coelicolor A3 (2) under nitrate-limited conditions
    • Karandikar A., Sharples G.P., Hobbs G. Differentiation of Streptomyces coelicolor A3 (2) under nitrate-limited conditions. Microbiology 1997, 143:3581-3590.
    • (1997) Microbiology , vol.143 , pp. 3581-3590
    • Karandikar, A.1    Sharples, G.P.2    Hobbs, G.3
  • 33
    • 33745699440 scopus 로고    scopus 로고
    • Involvement of nitrogen-containing compounds in β-lactam biosynthesis and its control
    • Demain A.L., Vaishnav P. Involvement of nitrogen-containing compounds in β-lactam biosynthesis and its control. Crit. Rev. Biotechnol. 2006, 26:67-82.
    • (2006) Crit. Rev. Biotechnol. , vol.26 , pp. 67-82
    • Demain, A.L.1    Vaishnav, P.2
  • 35
    • 84861880578 scopus 로고    scopus 로고
    • Optimized submerged batch fermentation strategy for systems scale studies of metabolic switching in Streptomyces coelicolor A3 (2)
    • Wentzel A., Bruheim P., Øverby A., Jakobsen Ø.M., Sletta H., Omara W.A., Hodgson D.A., Ellingsen T.E. Optimized submerged batch fermentation strategy for systems scale studies of metabolic switching in Streptomyces coelicolor A3 (2). BMC Syst. Biol. 2012, 6:59-75.
    • (2012) BMC Syst. Biol. , vol.6 , pp. 59-75
    • Wentzel, A.1    Bruheim, P.2    Øverby, A.3    Jakobsen, O.M.4    Sletta, H.5    Omara, W.A.6    Hodgson, D.A.7    Ellingsen, T.E.8
  • 36
    • 0017886045 scopus 로고
    • Carbon catabolite regulation of cephalosporin production in Streptomyces clavuligerus
    • Aharonowitz Y., Demain A.L. Carbon catabolite regulation of cephalosporin production in Streptomyces clavuligerus. Antimicrob. Agents Ch. 14 1978, 159-164.
    • (1978) Antimicrob. Agents Ch. 14 , pp. 159-164
    • Aharonowitz, Y.1    Demain, A.L.2
  • 37
    • 0025766432 scopus 로고
    • The effects of temperature, pH and growth rate on secondary metabolism in Streptomyces thermoviolaceus grown in a chemostat
    • James P.D.A., Edwards C., Dawson M. The effects of temperature, pH and growth rate on secondary metabolism in Streptomyces thermoviolaceus grown in a chemostat. J. Gen. Microbiol. 1991, 137:1715-1720.
    • (1991) J. Gen. Microbiol. , vol.137 , pp. 1715-1720
    • James, P.D.A.1    Edwards, C.2    Dawson, M.3
  • 38
    • 84865336020 scopus 로고    scopus 로고
    • Evaluation of nutrient uptake and physical parameters on cell biomass growth and production of spilanthol in suspension cultures of Spilanthes acmella Murr
    • Singh M., Chaturvedi R. Evaluation of nutrient uptake and physical parameters on cell biomass growth and production of spilanthol in suspension cultures of Spilanthes acmella Murr. Bioprocess Biosyst. Eng. 2012, 35:943-951.
    • (2012) Bioprocess Biosyst. Eng. , vol.35 , pp. 943-951
    • Singh, M.1    Chaturvedi, R.2
  • 39
    • 0027909872 scopus 로고
    • Analysis of metabolic fluxes in batch and continuous cultures of Bacillus subtilis
    • Goel A., Ferrance J., Jeong J., Ataai M.M. Analysis of metabolic fluxes in batch and continuous cultures of Bacillus subtilis. Biotechnol. Bioeng. 1993, 42:686-696.
    • (1993) Biotechnol. Bioeng. , vol.42 , pp. 686-696
    • Goel, A.1    Ferrance, J.2    Jeong, J.3    Ataai, M.M.4
  • 42
    • 0034691228 scopus 로고    scopus 로고
    • Application of metabolic flux analysis for the identification of metabolic bottlenecks in the biosynthesis of penicillin-G
    • Van Gulik W.M., De Laat W.T.A.M., Vinke J.L., Heijnen J.J. Application of metabolic flux analysis for the identification of metabolic bottlenecks in the biosynthesis of penicillin-G. Biotechnol. Bioeng. 2000, 68:602-618.
    • (2000) Biotechnol. Bioeng. , vol.68 , pp. 602-618
    • Van Gulik, W.M.1    De Laat, W.T.A.M.2    Vinke, J.L.3    Heijnen, J.J.4
  • 43
    • 84879059328 scopus 로고    scopus 로고
    • Production of clavulanic acid and cephamycin C by Streptomyces clavuligerus under different fed-batch conditions
    • Bellão C., Antonio T., Araujo M.L.G.C., Badino A.C. Production of clavulanic acid and cephamycin C by Streptomyces clavuligerus under different fed-batch conditions. Braz. J. Chem. Eng. 2013, 30:257-266.
    • (2013) Braz. J. Chem. Eng. , vol.30 , pp. 257-266
    • Bellão, C.1    Antonio, T.2    Araujo, M.L.G.C.3    Badino, A.C.4
  • 44
    • 84960117136 scopus 로고    scopus 로고
    • Dissociation of cephamycin C and clavulanic acid biosynthesis by 1, 3-diaminopropane in Streptomyces clavuligerus
    • fnv215
    • Leite C.A., Cavallieri A.P., Baptista A.S., Araujo M.L.G.C. Dissociation of cephamycin C and clavulanic acid biosynthesis by 1, 3-diaminopropane in Streptomyces clavuligerus. FEMS Microbiol. Lett. 2016, 363:fnv215.
    • (2016) FEMS Microbiol. Lett. , vol.363
    • Leite, C.A.1    Cavallieri, A.P.2    Baptista, A.S.3    Araujo, M.L.G.C.4
  • 45
    • 22944438700 scopus 로고    scopus 로고
    • Utilization of vegetable oil in the production of clavulanic acid by Streptomyces clavuligerus ATCC 27064
    • Maranesi G.L., Baptista-Neto A., Hokka C.O., Badino A.C. Utilization of vegetable oil in the production of clavulanic acid by Streptomyces clavuligerus ATCC 27064. World J. Microb. Biot. 2005, 21:509-514.
    • (2005) World J. Microb. Biot. , vol.21 , pp. 509-514
    • Maranesi, G.L.1    Baptista-Neto, A.2    Hokka, C.O.3    Badino, A.C.4


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