Downregulation of ACE2/Ang-(1-7)/Mas axis promotes breast cancer metastasis by enhancing store-operated calcium entry

Cancer Letters

Volumn 376, Issue 2, 2016, Pages 268-277

  Yu, Changhui ^a   Tang, Wei ^a   Wang, Yuhao ^a   Shen, Qiang ^a   Wang, Bin ^b   Cai, Chunqing ^a   Meng, Xiaojing ^a   Zou, Fei ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

ACE2 Ang (1 7) Mas axis; Breast cancer metastasis; E cadherin; PAK1 NF B Snail1 pathways; Store operated calcium entry (SOCE)

Indexed keywords

ANGIOTENSIN CONVERTING ENZYME 2; ANGIOTENSIN[1-7]; G PROTEIN COUPLED RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAS RECEPTOR; P21 ACTIVATED KINASE 1; SNAIL1 PROTEIN; TRANSCRIPTION FACTOR SNAIL; UNCLASSIFIED DRUG; UVOMORULIN; ANGIOTENSIN I; ANGIOTENSIN I (1-7); CADHERIN; CDH1 PROTEIN, HUMAN; DIPEPTIDYL CARBOXYPEPTIDASE; ONCOPROTEIN; P21 ACTIVATED KINASE; PAK1 PROTEIN, HUMAN; PEPTIDE FRAGMENT; PROTO-ONCOGENE PROTEINS C-MAS-1;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; BREAST CANCER CELL LINE; CALCIUM TRANSPORT; CANCER GRADING; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; DOWN REGULATION; FEMALE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LUNG METASTASIS; MAJOR CLINICAL STUDY; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STORE OPERATED CALCIUM ENTRY; UPREGULATION; ANIMAL; BREAST TUMOR; CALCIUM SIGNALING; CANCER TRANSPLANTATION; CELL MOTION; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; MCF-7 CELL LINE; METABOLISM; NONOBESE DIABETIC MOUSE; PATHOLOGY; RNA INTERFERENCE; SCID MOUSE; XENOGRAFT;

ANGIOTENSIN I; ANIMALS; BREAST NEOPLASMS; CADHERINS; CALCIUM SIGNALING; CELL MOVEMENT; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HETEROGRAFTS; HUMANS; MCF-7 CELLS; MICE, INBRED NOD; MICE, SCID; NEOPLASM GRADING; NEOPLASM METASTASIS; NEOPLASM TRANSPLANTATION; NF-KAPPA B; P21-ACTIVATED KINASES; PEPTIDE FRAGMENTS; PEPTIDYL-DIPEPTIDASE A; PROTO-ONCOGENE PROTEINS; RECEPTORS, G-PROTEIN-COUPLED; RNA INTERFERENCE; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 84962891475     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2016.04.006     Document Type: Article

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