Angiotensin-converting enzyme 2/angiotensin-(1-7)/mas axis protects against lung fibrosis by inhibiting the MAPK/NF-κB pathway

American Journal of Respiratory Cell and Molecular Biology

Volumn 50, Issue 4, 2014, Pages 723-736

  Meng, Ying ^a   Yu, Chang Hui ^a   Li, Wei ^a   Li, Ting ^a   Luo, Wei ^a   Huang, Shan ^a   Wu, Ping Sheng ^a   Cai, Shao Xi ^a   Li, Xu ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Angiotensin converting enzyme 2 angiotensin (1 7) mas axis; Mitogen activated protein kinases; NF B; Pulmonary fibrosis; Renin angiotensin system

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANGIOTENSIN CONVERTING ENZYME 2; ANGIOTENSIN[1-7]; ANGIOTENSIN[1-7][7 DEXTRO ALANINE]; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BLEOMYCIN; COLLAGEN TYPE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IRBESARTAN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN BCL 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FETUS; FETUS LUNG; FIBROBLAST; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LUNG FIBROSIS; LUNG PROTECTION; MALE; NONHUMAN; PROTECTION; RAT; UPREGULATION;

ANGIOTENSIN I; ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; APOPTOSIS; BCL-X PROTEIN; BLEOMYCIN; CELLS, CULTURED; COLLAGEN TYPE I; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; HUMANS; INFUSIONS, SUBCUTANEOUS; LUNG; MALE; MAP KINASE SIGNALING SYSTEM; NF-KAPPA B; PEPTIDE FRAGMENTS; PEPTIDYL-DIPEPTIDASE A; PHOSPHORYLATION; PNEUMONIA; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS; PULMONARY FIBROSIS; RATS; RATS, WISTAR; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84898730447     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2012-0451OC     Document Type: Article

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