메뉴 건너뛰기




Volumn 11, Issue 4, 2011, Pages 412-420

Role of the RAS in pancreatic cancer

Author keywords

Angiogenesis; Angiotensin II; Angiotensin II receotpr blocker (ARB); Angiotensin converting enzyme inhibitor (ACEI); Cytotoxicity; Pancreatic ductal adenocarcinoma (PDAC)

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN II; BRUCEA JAVANICA EXTRACT; CAMPTOTHECIN; CHINESE DRUG; COPTIS RHIZOME EXTRACT; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ERLOTINIB; FLUOROURACIL; GEMCITABINE;

EID: 79955616775     PISSN: 15680096     EISSN: None     Source Type: Journal    
DOI: 10.2174/156800911795538110     Document Type: Review
Times cited : (29)

References (104)
  • 1
    • 33947526470 scopus 로고    scopus 로고
    • The physiology of a local renin-angiotensin system in the pancrease
    • Leung, P. S. The physiology of a local renin-angiotensin system in the pancrease. J. Physiol. 2007, 580, 31-37.
    • (2007) J. Physiol. , vol.580 , pp. 31-37
    • Leung, P.S.1
  • 3
    • 0035957683 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor expression in human pancreatic cancer and growth inhibition by angiotensin II type 1 receptor antagonist
    • Fujimoto, Y.; Sasaki, T.; Tsuchida, A.; Chayama, K. Angiotensin II type 1 receptor expression in human pancreatic cancer and growth inhibition by angiotensin II type 1 receptor antagonist. FEBS Lett. 2001, 495, 197-200.
    • (2001) FEBS Lett. , vol.495 , pp. 197-200
    • Fujimoto, Y.1    Sasaki, T.2    Tsuchida, A.3    Chayama, K.4
  • 4
    • 0036098932 scopus 로고    scopus 로고
    • Angiotensin II stimulation of Na+/K+ATPase activity and cell growth by calcium-independent pathway in MCF-7 breast cancer cells
    • Muscella, A.; Greco, S.; Elia, M. G.; Storelli, C.; Marsigliante, S. Angiotensin II stimulation of Na+/K+ATPase activity and cell growth by calcium-independent pathway in MCF-7 breast cancer cells. J. Endocrinol. 2002, 173, 315-323.
    • (2002) J. Endocrinol. , vol.173 , pp. 315-323
    • Muscella, A.1    Greco, S.2    Elia, M.G.3    Storelli, C.4    Marsigliante, S.5
  • 6
    • 0032481348 scopus 로고    scopus 로고
    • Upregulation of vascular endothelial growth factor by angiotensin II in rat heart endothelial cells
    • Chua, C. C.; Hamdy, R. C.; Chua, B. H. Upregulation of vascular endothelial growth factor by angiotensin II in rat heart endothelial cells. Biochim. Biophys. Acta. 1998, 1401, 187-194
    • (1998) Biochim. Biophys. Acta. , vol.1401 , pp. 187-194
    • Chua, C.C.1    Hamdy, R.C.2    Chua, B.H.3
  • 8
    • 0036282389 scopus 로고    scopus 로고
    • Angiotensin II angiogenic effect in vivo involves vascular endothelial growth factor-and inflammation-related pathways
    • Tamarat, R.; Silvestre, J. S.; Durie, M.; Levy, B. I. Angiotensin II angiogenic effect in vivo involves vascular endothelial growth factor-and inflammation-related pathways. Lab. Invest. 2002, 82, 747-756.
    • (2002) Lab. Invest. , vol.82 , pp. 747-756
    • Tamarat, R.1    Silvestre, J.S.2    Durie, M.3    Levy, B.I.4
  • 9
    • 0030874825 scopus 로고    scopus 로고
    • Molecular genetics of human hypertension: Role of angiotensinogen
    • Corvol, P.; Jeunemaitre, X. Molecular genetics of human hypertension: role of angiotensinogen. Endocr. Rev. 1997, 18, 662-677.
    • (1997) Endocr. Rev. , vol.18 , pp. 662-677
    • Corvol, P.1    Jeunemaitre, X.2
  • 10
  • 11
    • 0033578910 scopus 로고    scopus 로고
    • Antiangiogenic activity of the cleaved conformation of the serpin antithrombin
    • O'Reilly, M. S.; Pirie-Shepherd, S.; Lane, W. S.; Folkman, J. Antiangiogenic activity of the cleaved conformation of the serpin antithrombin. Science 1999, 285, 1926-1928.
    • (1999) Science , vol.285 , pp. 1926-1928
    • O'Reilly, M.S.1    Pirie-Shepherd, S.2    Lane, W.S.3    Folkman, J.4
  • 12
    • 0033974302 scopus 로고    scopus 로고
    • Maspin is an angiogenesis inhibitor
    • Zhang, M.; Volpert, O.; Shi, Y. H.; Bouck, N. Maspin is an angiogenesis inhibitor. Nat. Med. 2000, 6, 196-199.
    • (2000) Nat. Med. , vol.6 , pp. 196-199
    • Zhang, M.1    Volpert, O.2    Shi, Y.H.3    Bouck, N.4
  • 14
    • 0036839310 scopus 로고    scopus 로고
    • Kallistatin is a new inhibitor of angiogenesis and tumor growth
    • Miao, R. Q.; Agata, J.; Chao, L.; Chao, J. Kallistatin is a new inhibitor of angiogenesis and tumor growth. Blood. 2002, 100, 3245-3252.
    • (2002) Blood. , vol.100 , pp. 3245-3252
    • Miao, R.Q.1    Agata, J.2    Chao, L.3    Chao, J.4
  • 15
    • 34247881844 scopus 로고    scopus 로고
    • Angiotensinogen impairs angiogenesis in the chick chorioallantoic membrane
    • Brand, M.; Lamandé, N.; Larger, E.; Corvol, P.; Gasc, J. M. Angiotensinogen impairs angiogenesis in the chick chorioallantoic membrane. J. Mol. Med. 2007, 85, 451-60.
    • (2007) J. Mol. Med. , vol.85 , pp. 451-460
    • Brand, M.1    Lamandé, N.2    Larger, E.3    Corvol, P.4    Gasc, J.M.5
  • 17
    • 0023764824 scopus 로고
    • The molecular heterogeneity of protein kinase C and its implications for cellular regulation
    • Nishizuka, Y. The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature. 1988, 334, 661-665.
    • (1988) Nature. , vol.334 , pp. 661-665
    • Nishizuka, Y.1
  • 20
    • 15444370455 scopus 로고    scopus 로고
    • Association of angiotensin-converting enzyme insertion/deletion polymorphism with serum level and development of pulmonary complications following esophagectomy
    • Lee, J. M.; Lo, A. C.; Yang, S. Y.; Tsau, H. S.; Chen, R. J.; Lee, Y. C. Association of angiotensin-converting enzyme insertion/deletion polymorphism with serum level and development of pulmonary complications following esophagectomy. Ann. Surg. 2005, 241, 659-665.
    • (2005) Ann. Surg. , vol.241 , pp. 659-665
    • Lee, J.M.1    Lo, A.C.2    Yang, S.Y.3    Tsau, H.S.4    Chen, R.J.5    Lee, Y.C.6
  • 21
    • 0036800652 scopus 로고    scopus 로고
    • Suppression of basic fibroblast growth factor-induced angiogenesis by a specific chymase inhibitor, BCEAB, through the chymase-angiotensindependent pathway in hamster sponge granulomas
    • Muramatsu, M.; Yamada, M.; Takai, S.; Miyazaki, M. Suppression of basic fibroblast growth factor-induced angiogenesis by a specific chymase inhibitor, BCEAB, through the chymase-angiotensindependent pathway in hamster sponge granulomas. Br. J. Pharmacol. 2002, 137, 554-560.
    • (2002) Br. J. Pharmacol. , vol.137 , pp. 554-560
    • Muramatsu, M.1    Yamada, M.2    Takai, S.3    Miyazaki, M.4
  • 24
    • 0030054914 scopus 로고    scopus 로고
    • Regulation of VEGF/VPF expression in tumor cells: Consequences for tumor growth and metastasis
    • Claffey, K. P.; Robinson, G. S. Regulation of VEGF/VPF expression in tumor cells: consequences for tumor growth and metastasis. Cancer Metastasis Rev. 1996, 15, 165-176.
    • (1996) Cancer Metastasis Rev. , vol.15 , pp. 165-176
    • Claffey, K.P.1    Robinson, G.S.2
  • 25
    • 0035675877 scopus 로고    scopus 로고
    • The prognostic relevance of angiogenesis and mast cells in squamous cell carcinoma of the oesophagus
    • Elpek, G. O.; Gelen, T.; Aksoy, N. H.; Erdoǧan, A.; Dertsiz, L.; Demircan, A.; Keleş, N. The prognostic relevance of angiogenesis and mast cells in squamous cell carcinoma of the oesophagus. J. Clin. Pathol. 2001, 54, 940-944.
    • (2001) J. Clin. Pathol. , vol.54 , pp. 940-944
    • Elpek, G.O.1    Gelen, T.2    Aksoy, N.H.3    Erdoǧan, A.4    Dertsiz, L.5    Demircan, A.6    Keleş, N.7
  • 26
    • 0035574310 scopus 로고    scopus 로고
    • Angiogenesis, angiogenic factor expression and prognosis of gastric carcinoma
    • Saito, H.; Tsujitani, S. Angiogenesis, angiogenic factor expression and prognosis of gastric carcinoma. Anticancer Res. 2001, 21, 4365-4372.
    • (2001) Anticancer Res. , vol.21 , pp. 4365-4372
    • Saito, H.1    Tsujitani, S.2
  • 27
    • 0034895599 scopus 로고    scopus 로고
    • Tumor angiogenesis and its possible role in intravasation of colorectal epithelial cells
    • Tien, Y. W.; Chang, K. J.; Jeng, Y. M.; Lee, P. H.; Wu, M. S.; Lin, J. T.; Hsu, S. M. Tumor angiogenesis and its possible role in intravasation of colorectal epithelial cells. Clin. Cancer Res. 2001, 7, 1627-1632.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 1627-1632
    • Tien, Y.W.1    Chang, K.J.2    Jeng, Y.M.3    Lee, P.H.4    Wu, M.S.5    Lin, J.T.6    Hsu, S.M.7
  • 29
    • 0029061789 scopus 로고
    • Angiotensin II increases vascular permeability factor gene expression by human vascular smooth muscle cells
    • Williams, B.; Baker, A. Q.; Gallacher, B.; Lodwick, D. Angiotensin II increases vascular permeability factor gene expression by human vascular smooth muscle cells. Hypertension 1995, 25, 913-917.
    • (1995) Hypertension , vol.25 , pp. 913-917
    • Williams, B.1    Baker, A.Q.2    Gallacher, B.3    Lodwick, D.4
  • 30
    • 1842346472 scopus 로고    scopus 로고
    • Molecular mechanisms of vasculogenesis and embryonic angiogenesis
    • Flamme, I.; Frölich, T.; Risau, W. Molecular mechanisms of vasculogenesis and embryonic angiogenesis. J. Cell Physiol. 1997, 173, 206-210.
    • (1997) J. Cell Physiol. , vol.173 , pp. 206-210
    • Flamme, I.1    Frölich, T.2    Risau, W.3
  • 31
    • 0030952289 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis
    • Risau, W. Mechanisms of angiogenesis. Nature 1997, 386, 671-674.
    • (1997) Nature , vol.386 , pp. 671-674
    • Risau, W.1
  • 32
    • 33749004555 scopus 로고    scopus 로고
    • Vascular endothelial growth factor overexpression by soft tissue sarcoma cells: Implications for tumor growth, metastasis, and chemoresistance
    • Zhang, L.; Hannay, J.A.; Liu, J.; Das, P.; Zhan, M.; Nguyen, T.; Hicklin, D. J.; Yu, D.; Pollock, R. E.; Lev, D. Vascular endothelial growth factor overexpression by soft tissue sarcoma cells: implications for tumor growth, metastasis, and chemoresistance. Cancer Res. 2006, 66, 8770-8778.
    • (2006) Cancer Res. , vol.66 , pp. 8770-8778
    • Zhang, L.1    Hannay, J.A.2    Liu, J.3    Das, P.4    Zhan, M.5    Nguyen, T.6    Hicklin, D.J.7    Yu, D.8    Pollock, R.E.9    Lev, D.10
  • 33
    • 33644532890 scopus 로고    scopus 로고
    • Tumor angiogenesis and therapy
    • Cao, Y. Tumor angiogenesis and therapy. Biomed. Pharmacother. 2005, 59, S340-S343.
    • (2005) Biomed. Pharmacother. , vol.59
    • Cao, Y.1
  • 34
    • 0034987872 scopus 로고    scopus 로고
    • Angiogenesis during follicular development in the primate and its inhibition by treatment with truncated Flt-1-Fc (vascular endothelial growth factor Trap(A40)
    • Wulff, C.; Wiegand, S. J.; Saunders, P. T.; Scobie, G. A.; Fraser, H. M. Angiogenesis during follicular development in the primate and its inhibition by treatment with truncated Flt-1-Fc (vascular endothelial growth factor Trap(A40). Endocrinology 2001, 142, 3244-3254.
    • (2001) Endocrinology , vol.142 , pp. 3244-3254
    • Wulff, C.1    Wiegand, S.J.2    Saunders, P.T.3    Scobie, G.A.4    Fraser, H.M.5
  • 35
    • 0036287302 scopus 로고    scopus 로고
    • Prevention of thecal angiogenesis, antral follicular growth, and ovulation in the primate by treatment with vascular endothelial growth factor Trap R1R2
    • Wulff, C.; Wilson, H.; Wiegand, S. J.; Rudge, J. S.; Fraser, H. M. Prevention of thecal angiogenesis, antral follicular growth, and ovulation in the primate by treatment with vascular endothelial growth factor Trap R1R2. Endocrinology 2002, 143, 2797-2807.
    • (2002) Endocrinology , vol.143 , pp. 2797-2807
    • Wulff, C.1    Wilson, H.2    Wiegand, S.J.3    Rudge, J.S.4    Fraser, H.M.5
  • 36
    • 33748529321 scopus 로고    scopus 로고
    • Monoclonal antibody-based targeted therapy in breast cancer: Current status and future directions
    • Bernard-Marty, C.; Lebrun, F.; Awada, A.; Piccart, M. J. Monoclonal antibody-based targeted therapy in breast cancer: current status and future directions. Drugs 2006, 66, 1577-1591.
    • (2006) Drugs , vol.66 , pp. 1577-1591
    • Bernard-Marty, C.1    Lebrun, F.2    Awada, A.3    Piccart, M.J.4
  • 39
    • 0034805542 scopus 로고    scopus 로고
    • Growth stimulatory angiotensin II type-1 receptor is upregulated in breast hyperplasia and in situ carcinoma but not in invasive carcinoma
    • De Paepe, B.; Verstraeten, V. L.; De Potter, C. R.; Vakaet, L. A.; Bullock, G. R. Growth stimulatory angiotensin II type-1 receptor is upregulated in breast hyperplasia and in situ carcinoma but not in invasive carcinoma. Histochem. Cell Biol. 2001, 116, 247-254.
    • (2001) Histochem. Cell Biol. , vol.116 , pp. 247-254
    • de Paepe, B.1    Verstraeten, V.L.2    de Potter, C.R.3    Vakaet, L.A.4    Bullock, G.R.5
  • 41
    • 34147126027 scopus 로고    scopus 로고
    • Enhanced angiotensin II production by renal mesangium is responsible for apoptosis/proliferation of endothelial and epithelial cells in a model of malignant hypertension
    • Efrati, S.; Berman, S.; Goldfinger, N.; Erez, N.; Averbukh, Z.; Golik, A.; Rotter, V.; Weissgarten, J. Enhanced angiotensin II production by renal mesangium is responsible for apoptosis/proliferation of endothelial and epithelial cells in a model of malignant hypertension. J. Hypertens. 2007, 25, 1041-1052.
    • (2007) J. Hypertens. , vol.25 , pp. 1041-1052
    • Efrati, S.1    Berman, S.2    Goldfinger, N.3    Erez, N.4    Averbukh, Z.5    Golik, A.6    Rotter, V.7    Weissgarten, J.8
  • 42
    • 0034887741 scopus 로고    scopus 로고
    • Production and localisation of angiotensin II in the bovine early corpus luteum: A possible interaction with luteal angiogenic factors and prostaglandin F2 alpha
    • Kobayashi, S.; Berisha, B.; Amselgruber, W. M.; Schams, D.; Miyamoto, A. Production and localisation of angiotensin II in the bovine early corpus luteum: a possible interaction with luteal angiogenic factors and prostaglandin F2 alpha. J. Endocrinol. 2001, 170, 369-380.
    • (2001) J. Endocrinol. , vol.170 , pp. 369-380
    • Kobayashi, S.1    Berisha, B.2    Amselgruber, W.M.3    Schams, D.4    Miyamoto, A.5
  • 43
    • 17644416741 scopus 로고    scopus 로고
    • Functional expression of the angiotensin II type 1 receptor in human ovarian carcinoma cells and its blockade therapy resulting in suppression of tumor invasion, angiogenesis, and peritoneal dissemination
    • Suganuma, T.; Ino, K.; Shibata, K.; Kajiyama, H.; Nagasaka, T.; Mizutani, S.; Kikkawa, F. Functional expression of the angiotensin II type 1 receptor in human ovarian carcinoma cells and its blockade therapy resulting in suppression of tumor invasion, angiogenesis, and peritoneal dissemination. Clin. Cancer Res. 2005, 11, 2686-2694.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 2686-2694
    • Suganuma, T.1    Ino, K.2    Shibata, K.3    Kajiyama, H.4    Nagasaka, T.5    Mizutani, S.6    Kikkawa, F.7
  • 46
    • 33746143521 scopus 로고    scopus 로고
    • Signal transducers and activators of transcription 3 mediates up-regulation of angiotensin II-induced tissue inhibitor of metalloproteinase-1 expression in cultured human senescent fibroblasts
    • Wang, X. D.; Chen, X. M.; Wang, J. Z.; Hong, Q.; Feng, Z.; Fu, B.; Zhou, F.; Wang, F. Y.; Fan, D. M. Signal transducers and activators of transcription 3 mediates up-regulation of angiotensin II-induced tissue inhibitor of metalloproteinase-1 expression in cultured human senescent fibroblasts. Chin. Med. J. (Engl). 2006, 119, 1094-1102.
    • (2006) Chin. Med. J. (Engl). , vol.119 , pp. 1094-1102
    • Wang, X.D.1    Chen, X.M.2    Wang, J.Z.3    Hong, Q.4    Feng, Z.5    Fu, B.6    Zhou, F.7    Wang, F.Y.8    Fan, D.M.9
  • 47
    • 22044440743 scopus 로고    scopus 로고
    • Angiotensin II stimulates hypoxia-inducible factor 1alpha accumulation in glomerular mesangial cells
    • Chen, T. H.; Wang, J. F.; Chan, P.; Lee, H. M. Angiotensin II stimulates hypoxia-inducible factor 1alpha accumulation in glomerular mesangial cells. Ann. N.Y. Acad. Sci. 2005, 1042, 286-93.
    • (2005) Ann. N.Y. Acad. Sci. , vol.1042 , pp. 286-293
    • Chen, T.H.1    Wang, J.F.2    Chan, P.3    Lee, H.M.4
  • 48
    • 24144469144 scopus 로고    scopus 로고
    • Angiotensin II regulates vascular endothelial growth factor via hypoxia-inducible factor-1alpha induction and redox mechanisms in the kidney
    • Sánchez-López, E.; López, A. F.; Esteban, V.; Yagüe, S.; Egido, J.; Ruiz-Ortega, M.; Alvarez-Arroyo, M. V. Angiotensin II regulates vascular endothelial growth factor via hypoxia-inducible factor-1alpha induction and redox mechanisms in the kidney. Antioxid. Redox Signal 2005, 7, 1275-1284.
    • (2005) Antioxid. Redox Signal , vol.7 , pp. 1275-1284
    • Sánchez-López, E.1    López, A.F.2    Esteban, V.3    Yagüe, S.4    Egido, J.5    Ruiz-Ortega, M.6    Alvarez-Arroyo, M.V.7
  • 49
    • 0031937612 scopus 로고    scopus 로고
    • Captopril inhibits tumour growth in a xenograft model of human renal cell carcinoma
    • Hii, S. I.; Nicol, D. L.; Gotley, D. C.; Thompson, L. C.; Green, M. K.; Jonsson, J. R. Captopril inhibits tumour growth in a xenograft model of human renal cell carcinoma. Br. J. Cancer 1998, 77, 880-883.
    • (1998) Br. J. Cancer , vol.77 , pp. 880-883
    • Hii, S.I.1    Nicol, D.L.2    Gotley, D.C.3    Thompson, L.C.4    Green, M.K.5    Jonsson, J.R.6
  • 52
    • 0035008410 scopus 로고    scopus 로고
    • Differences between squamous cell carcinoma and keratoacanthoma in angiotensin type-1 receptor expression
    • Takeda, H.; Kondo, S. Differences between squamous cell carcinoma and keratoacanthoma in angiotensin type-1 receptor expression. Am. J. Pathol. 2001, 158, 1633-1637.
    • (2001) Am. J. Pathol. , vol.158 , pp. 1633-1637
    • Takeda, H.1    Kondo, S.2
  • 53
    • 77954129591 scopus 로고    scopus 로고
    • Blocking angiotensin II type 1 receptor triggers apoptotic cell death in human pancreatic cancer cells
    • Gong, Q.; Davis, M.; Chipitsyna, G.; Yeo, C. J.; Arafat, H.A. Blocking angiotensin II type 1 receptor triggers apoptotic cell death in human pancreatic cancer cells. Pancreas 2010, 39, 581-594.
    • (2010) Pancreas , vol.39 , pp. 581-594
    • Gong, Q.1    Davis, M.2    Chipitsyna, G.3    Yeo, C.J.4    Arafat, H.A.5
  • 55
    • 71149097464 scopus 로고    scopus 로고
    • Angiotensin II regulates the expression of monocyte chemoattractant protein-1 in pancreatic cancer cells
    • Chehl, N.; Gong, Q.; Chipitsyna, G.; Aziz, T.; Yeo, C. J.; Arafat, H. A. Angiotensin II regulates the expression of monocyte chemoattractant protein-1 in pancreatic cancer cells. J. Gastrointest. Surg. 2009, 13, 2189-2200.
    • (2009) J. Gastrointest. Surg. , vol.13 , pp. 2189-2200
    • Chehl, N.1    Gong, Q.2    Chipitsyna, G.3    Aziz, T.4    Yeo, C.J.5    Arafat, H.A.6
  • 56
    • 23944434473 scopus 로고    scopus 로고
    • Angiotensin receptors: A new role in cancer?
    • Deshayes, F.; Nahmias, C. Angiotensin receptors: a new role in cancer? Trends Endocrinol. Metab. 2005, 16, 293-299.
    • (2005) Trends Endocrinol. Metab. , vol.16 , pp. 293-299
    • Deshayes, F.1    Nahmias, C.2
  • 57
    • 0035240199 scopus 로고    scopus 로고
    • The pancreatic renin-angiotensin system: Does it play a role in endocrine oncology
    • Lam, K. Y. The pancreatic renin-angiotensin system: does it play a role in endocrine oncology. J.O.P. 2001, 2, 40-42.
    • (2001) J.O.P. , vol.2 , pp. 40-42
    • Lam, K.Y.1
  • 58
    • 0036224357 scopus 로고    scopus 로고
    • Regulation and expression of a reninangiotensin system in human pancreas and pancreatic endocrine tumours
    • Lam, K. Y.; Leung, P. S. Regulation and expression of a reninangiotensin system in human pancreas and pancreatic endocrine tumours. Eur. J. Endocrinol. 2002, 146, 567-572.
    • (2002) Eur. J. Endocrinol. , vol.146 , pp. 567-572
    • Lam, K.Y.1    Leung, P.S.2
  • 59
    • 38349006745 scopus 로고    scopus 로고
    • Angiotensin II induces vascular endothelial growth factor in pancreatic cancer cells through an angiotensin II type 1 receptor and ERK1/2 signaling
    • Anandanadesan, R.; Gong, Q.; Chipitsyna, G.; Witkiewicz, A.; Yeo, C. J.; Arafat, H. A. Angiotensin II induces vascular endothelial growth factor in pancreatic cancer cells through an angiotensin II type 1 receptor and ERK1/2 signaling. J. Gastrointest. Surg. 2008, 12, 57-66.
    • (2008) J. Gastrointest. Surg. , vol.12 , pp. 57-66
    • Anandanadesan, R.1    Gong, Q.2    Chipitsyna, G.3    Witkiewicz, A.4    Yeo, C.J.5    Arafat, H.A.6
  • 60
    • 34247511935 scopus 로고    scopus 로고
    • Antihypertensives as novel antineoplastics: Angiotensin-Iconverting enzyme inhibitors and angiotensin II type 1 receptor blockers in pancreatic ductal adenocarcinoma
    • Arafat, H. A.; Gong, Q.; Chipitsyna, G.; Rizvi, A.; Saa, C. T.; Yeo, C. J. Antihypertensives as novel antineoplastics: angiotensin-Iconverting enzyme inhibitors and angiotensin II type 1 receptor blockers in pancreatic ductal adenocarcinoma. J. Am. Coll. Surg. 2007, 204, 996-1005.
    • (2007) J. Am. Coll. Surg. , vol.204 , pp. 996-1005
    • Arafat, H.A.1    Gong, Q.2    Chipitsyna, G.3    Rizvi, A.4    Saa, C.T.5    Yeo, C.J.6
  • 61
    • 2342570909 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor mRNA and its protein expression in human pancreatic cancer cell lines
    • Jiang, H.; Li, Z. S.; Xu, G. M.; Tu, Z. X.; Gong, Y. F. Angiotensin II type 1 receptor mRNA and its protein expression in human pancreatic cancer cell lines. Chin. J. Dig. Dis. 2004, 5, 68-71.
    • (2004) Chin. J. Dig. Dis. , vol.5 , pp. 68-71
    • Jiang, H.1    Li, Z.S.2    Xu, G.M.3    Tu, Z.X.4    Gong, Y.F.5
  • 62
    • 18044364823 scopus 로고    scopus 로고
    • Blockage of angiotensin II type I receptor decreases the synthesis of growth factors and induces apoptosis in C6 cultured cells and C6 rat glioma
    • Arrieta, O.; Guevara, P.; Escobar, E.; García-Navarrete, R.; Pineda, B.; Sotelo, J. Blockage of angiotensin II type I receptor decreases the synthesis of growth factors and induces apoptosis in C6 cultured cells and C6 rat glioma. Br. J. Cancer. 2005, 92, 1247-1252.
    • (2005) Br. J. Cancer. , vol.92 , pp. 1247-1252
    • Arrieta, O.1    Guevara, P.2    Escobar, E.3    García-Navarrete, R.4    Pineda, B.5    Sotelo, J.6
  • 64
    • 34547951695 scopus 로고    scopus 로고
    • ACE2: A new target for cardiovascular disease therapeutics
    • Raizada, M. K.; Ferreira, A. J. ACE2: a new target for cardiovascular disease therapeutics. J. Cardiovasc. Pharmacol. 2007, 50, 112-119.
    • (2007) J. Cardiovasc. Pharmacol. , vol.50 , pp. 112-119
    • Raizada, M.K.1    Ferreira, A.J.2
  • 66
    • 43049103449 scopus 로고    scopus 로고
    • Urinary mRNA expression of ACE and ACE2 in human type 2 diabetic nephropathy
    • Wang, G.; Lai, F. M.; Lai, K. B.; Chow, K. M.; Kwan, C. H.; Li, K. T.; Szeto, C. C. Urinary mRNA expression of ACE and ACE2 in human type 2 diabetic nephropathy. Diabetologia 2008, 51, 1062-1067.
    • (2008) Diabetologia , vol.51 , pp. 1062-1067
    • Wang, G.1    Lai, F.M.2    Lai, K.B.3    Chow, K.M.4    Kwan, C.H.5    Li, K.T.6    Szeto, C.C.7
  • 67
    • 66949178060 scopus 로고    scopus 로고
    • Decreased expression of angiotensinconverting enzyme 2 in pancreatic ductal adenocarcinoma is associated with tumor progression
    • Zhou, L.; Zhang, R.; Yao, W.; Wang, J.; Qian, A.; Qiao, M.; Zhang, Y.; Yuan, Y. Decreased expression of angiotensinconverting enzyme 2 in pancreatic ductal adenocarcinoma is associated with tumor progression. Tohoku J. Exp. Med. 2009, 217, 123-13
    • (2009) Tohoku J. Exp. Med. , vol.217 , pp. 123-133
    • Zhou, L.1    Zhang, R.2    Yao, W.3    Wang, J.4    Qian, A.5    Qiao, M.6    Zhang, Y.7    Yuan, Y.8
  • 68
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan, D.; Weinberg, R. A. The hallmarks of cancer. Cell. 2000, 100, 57-70.
    • (2000) Cell. , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 70
    • 0037058302 scopus 로고    scopus 로고
    • Effect of the vascular endothelial growth factor receptor-2 antibody DC101 plus gemcitabine on growth, metastasis and angiogenesis of human pancreatic cancer growing orthotopically in nude mice
    • Bruns, C. J.; Shrader, M.; Harbison, M. T.; Portera, C.; Solorzano, C. C.; Jauch, K. W.; Hicklin, D. J.; Radinsky, R.; Ellis, L. M. Effect of the vascular endothelial growth factor receptor-2 antibody DC101 plus gemcitabine on growth, metastasis and angiogenesis of human pancreatic cancer growing orthotopically in nude mice. Int. J. Cancer. 2002, 102, 101-108.
    • (2002) Int. J. Cancer. , vol.102 , pp. 101-108
    • Bruns, C.J.1    Shrader, M.2    Harbison, M.T.3    Portera, C.4    Solorzano, C.C.5    Jauch, K.W.6    Hicklin, D.J.7    Radinsky, R.8    Ellis, L.M.9
  • 71
    • 12344312012 scopus 로고    scopus 로고
    • Antiangiogenic therapy for human pancreatic carcinoma xenografts in nude mice
    • Jia, L.; Zhang, M. H.; Yuan, S. Z.; Huang, W. G. Antiangiogenic therapy for human pancreatic carcinoma xenografts in nude mice. World J. Gastroenterol. 2005, 11, 47-450.
    • (2005) World J. Gastroenterol. , vol.11 , pp. 47-450
    • Jia, L.1    Zhang, M.H.2    Yuan, S.Z.3    Huang, W.G.4
  • 73
    • 23044432250 scopus 로고    scopus 로고
    • Antiangiogenic treatment with three thrombospondin-1 type 1 repeats versus gemcitabine in an orthotopic human pancreatic cancer model
    • Zhang, X.; Galardi, E.; Duquette, M.; Lawler, J.; Parangi, S. Antiangiogenic treatment with three thrombospondin-1 type 1 repeats versus gemcitabine in an orthotopic human pancreatic cancer model. Clin. Cancer Res. 2005, 11, 5622-5630.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 5622-5630
    • Zhang, X.1    Galardi, E.2    Duquette, M.3    Lawler, J.4    Parangi, S.5
  • 74
    • 79955615188 scopus 로고    scopus 로고
    • Pathways for aberrant angiogenesis in pancreatic cancer
    • Korc, M. Pathways for aberrant angiogenesis in pancreatic cancer. Mol. Cancer 2001, 7, 2-8.
    • (2001) Mol. Cancer , vol.7 , pp. 2-8
    • Korc, M.1
  • 77
    • 0030754056 scopus 로고    scopus 로고
    • Enhanced expression of vascular endothelial growth factor in human pancreatic cancer correlates with local disease progression
    • Itakura, J.; Ishiwata, T.; Friess, H.; Fujii, H.; Matsumoto, Y.; Büchler, M. W.; Korc, M. Enhanced expression of vascular endothelial growth factor in human pancreatic cancer correlates with local disease progression. Clin. Cancer Res. 1997, 3, 1309-1316.
    • (1997) Clin. Cancer Res. , vol.3 , pp. 1309-1316
    • Itakura, J.1    Ishiwata, T.2    Friess, H.3    Fujii, H.4    Matsumoto, Y.5    Büchler, M.W.6    Korc, M.7
  • 78
    • 0033991167 scopus 로고    scopus 로고
    • Concomitant over-expression of vascular endothelial growth factor and its receptors in pancreatic cancer
    • Itakura, J.; Ishiwata, T.; Shen, B.; Kornmann, M.; Korc, M. Concomitant over-expression of vascular endothelial growth factor and its receptors in pancreatic cancer. Int. J. Cancer 2000, 85, 27-34.
    • (2000) Int. J. Cancer , vol.85 , pp. 27-34
    • Itakura, J.1    Ishiwata, T.2    Shen, B.3    Kornmann, M.4    Korc, M.5
  • 79
    • 0034657029 scopus 로고    scopus 로고
    • High expression of vascular endothelial growth factor is associated with liver metastasis and a poor prognosis for patients with ductal pancreatic adenocarcinoma
    • Seo, Y.; Baba, H.; Fukuda, T.; Takashima, M.; Sugimachi, K. High expression of vascular endothelial growth factor is associated with liver metastasis and a poor prognosis for patients with ductal pancreatic adenocarcinoma. Cancer 2000, 88, 2239-2245.
    • (2000) Cancer , vol.88 , pp. 2239-2245
    • Seo, Y.1    Baba, H.2    Fukuda, T.3    Takashima, M.4    Sugimachi, K.5
  • 81
    • 0036006171 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF), a survival factor for tumour cells: Implications for anti-angiogenic therapy
    • Harmey, J. H.; Bouchier-Hayes, D. Vascular endothelial growth factor (VEGF), a survival factor for tumour cells: implications for anti-angiogenic therapy. Bioessays 2002, 24, 280-283.
    • (2002) Bioessays , vol.24 , pp. 280-283
    • Harmey, J.H.1    Bouchier-Hayes, D.2
  • 84
    • 16644396484 scopus 로고    scopus 로고
    • Angiotensin II activates MAP kinase and NF-kappaB through angiotensin II type I receptor in human pancreatic cancer cells
    • Amaya, K.; Ohta, T.; Kitagawa, H.; Kayahara, M.; Takamura, H.; Fujimura, T.; Nishimura, G.; Shimizu, K.; Miwa, K. Angiotensin II activates MAP kinase and NF-kappaB through angiotensin II type I receptor in human pancreatic cancer cells. Int. J. Oncol. 2004, 25, 849-856.
    • (2004) Int. J. Oncol. , vol.25 , pp. 849-856
    • Amaya, K.1    Ohta, T.2    Kitagawa, H.3    Kayahara, M.4    Takamura, H.5    Fujimura, T.6    Nishimura, G.7    Shimizu, K.8    Miwa, K.9
  • 85
    • 0027461223 scopus 로고
    • Adjuvant combination chemotherapy (AMF) following radical resection of carcinoma of the pancreas and papilla of Vater-results of a controlled, prospective, randomised multicentre study
    • Bakkevold, K. E.; Arnesjo, B.; Dahl, O.; Kambestad, B. Adjuvant combination chemotherapy (AMF) following radical resection of carcinoma of the pancreas and papilla of Vater-results of a controlled, prospective, randomised multicentre study. Eur. J. Cancer 1993, 29A, 698-703.
    • (1993) Eur. J. Cancer , vol.29 A , pp. 698-703
    • Bakkevold, K.E.1    Arnesjo, B.2    Dahl, O.3    Kambestad, B.4
  • 86
    • 0037699955 scopus 로고    scopus 로고
    • Angiogenesis in health and disease
    • Carmeliet, P. Angiogenesis in health and disease. Nat. Med. 2003, 9, 653-660.
    • (2003) Nat. Med. , vol.9 , pp. 653-660
    • Carmeliet, P.1
  • 93
    • 1842609941 scopus 로고    scopus 로고
    • Inhibition of AKT abrogates chemotherapy-induced NF-kappaB survival mechanisms: Implications for therapy in pancreatic cancer
    • Fahy, B. N.; Schlieman, M. G.; Virudachalam, S.; Bold, R. J. Inhibition of AKT abrogates chemotherapy-induced NF-kappaB survival mechanisms: implications for therapy in pancreatic cancer. J. Am. Coll. Surg. 2004, 198, 591-599
    • (2004) J. Am. Coll. Surg. , vol.198 , pp. 591-599
    • Fahy, B.N.1    Schlieman, M.G.2    Virudachalam, S.3    Bold, R.J.4
  • 95
    • 4344626528 scopus 로고    scopus 로고
    • Phase II study of radiotherapy combined with gemcitabine for locally advanced pancreatic cancer
    • Okusaka, T.; Ito, Y.; Ueno, H.; Ikeda, M.; Takezako, Y.; Morizane, C.; Kagami, Y.; Ikeda, H. Phase II study of radiotherapy combined with gemcitabine for locally advanced pancreatic cancer. Br. J. Cancer 2004, 91, 673-677.
    • (2004) Br. J. Cancer , vol.91 , pp. 673-677
    • Okusaka, T.1    Ito, Y.2    Ueno, H.3    Ikeda, M.4    Takezako, Y.5    Morizane, C.6    Kagami, Y.7    Ikeda, H.8
  • 96
    • 67349190115 scopus 로고    scopus 로고
    • Brucein D induces apoptosis in pancreatic adenocarcinoma cell line PANC-1 through the activation of p38-mitogen activated protein kinase
    • Lau, S. T.; Lin, Z. X.; Liao, Y.; Zhao, M.; Cheng, C. H.; Leung, P. S. Brucein D induces apoptosis in pancreatic adenocarcinoma cell line PANC-1 through the activation of p38-mitogen activated protein kinase. Cancer Lett. 2009, 281, 42-52.
    • (2009) Cancer Lett. , vol.281 , pp. 42-52
    • Lau, S.T.1    Lin, Z.X.2    Liao, Y.3    Zhao, M.4    Cheng, C.H.5    Leung, P.S.6
  • 97
    • 42949125901 scopus 로고    scopus 로고
    • Brucea javanica fruit induces cytotoxicity and apoptosis in pancreatic adenocarcinoma cell lines
    • Lau, S. T.; Lin, Z. X.; Zhao, M.; Leung, P. S. Brucea javanica fruit induces cytotoxicity and apoptosis in pancreatic adenocarcinoma cell lines. Phytother. Res. 2008, 22, 477-486.
    • (2008) Phytother. Res. , vol.22 , pp. 477-486
    • Lau, S.T.1    Lin, Z.X.2    Zhao, M.3    Leung, P.S.4
  • 98
    • 76349122924 scopus 로고    scopus 로고
    • Role of reactive oxygen species in brucein D-mediated p38-mitogen-activated protein kinase and nuclear factor-kappaB signalling pathways in human pancreatic adenocarcinoma cells
    • Lau, S. T.; Lin, Z. X.; Leung, P. S. Role of reactive oxygen species in brucein D-mediated p38-mitogen-activated protein kinase and nuclear factor-kappaB signalling pathways in human pancreatic adenocarcinoma cells. Br. J. Cancer 2010, 102, 583-593.
    • (2010) Br. J. Cancer , vol.102 , pp. 583-593
    • Lau, S.T.1    Lin, Z.X.2    Leung, P.S.3
  • 101
    • 0037963091 scopus 로고    scopus 로고
    • Angiotensin-I-converting enzyme inhibitors may be an alternative anti-angiogenic strategy in the treatment of liver fibrosis and hepatocellular carcinoma. Possible role of vascular endothelial growth factor
    • Yoshiji, H.; Kuriyama, S.; Fukui, H. Angiotensin-I-converting enzyme inhibitors may be an alternative anti-angiogenic strategy in the treatment of liver fibrosis and hepatocellular carcinoma. Possible role of vascular endothelial growth factor. Tumor Biol. 2002, 23, 348-356.
    • (2002) Tumor Biol. , vol.23 , pp. 348-356
    • Yoshiji, H.1    Kuriyama, S.2    Fukui, H.3
  • 103
    • 42649136964 scopus 로고    scopus 로고
    • Increased expression of angiotensin converting enzyme 2 in conjunction with reduction of neointima by angiotensin II type 1 receptor blockade
    • Igase, M.; Kohara, K.; Nagai, T.; Miki, T.; Ferrario, C. M. Increased expression of angiotensin converting enzyme 2 in conjunction with reduction of neointima by angiotensin II type 1 receptor blockade. Hypertens. Res. 2008, 31, 553-559.
    • (2008) Hypertens. Res. , vol.31 , pp. 553-559
    • Igase, M.1    Kohara, K.2    Nagai, T.3    Miki, T.4    Ferrario, C.M.5
  • 104
    • 0033853171 scopus 로고    scopus 로고
    • Anti-angiogenic agents: Clinical trial design and therapies in development
    • Deplanque, G.; Harris, A. L. Anti-angiogenic agents: clinical trial design and therapies in development. Eur. J. Cancer. 2000, 36, 1713-1724.
    • (2000) Eur. J. Cancer. , vol.36 , pp. 1713-1724
    • Deplanque, G.1    Harris, A.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.