Dual effects of quercetin in doxorubicin-induced nephrotoxicity in rats and its modulation of the cytotoxic activity of doxorubicin on human carcinoma cells

Environmental Toxicology

Volumn 31, Issue 5, 2016, Pages 624-636

  Heeba, Gehan H ^a   Mahmoud, Magda E ^b  

^a Minia University   (Egypt)

^b Minia University   (Egypt)

Author keywords

Apoptosis; Cytotoxicity; Doxorubicin; Nephrotoxicity; Oxidative stress; Quercetin

Indexed keywords

CELL CULTURE; CELL DEATH; CYTOLOGY; CYTOTOXICITY; DISEASES; FLAVONOIDS; MODULATION; NITRIC OXIDE; OXIDANTS; OXIDATIVE STRESS; PHENOLS; RATS; UREA;

BLOOD UREA NITROGENS; CYTOTOXIC ACTIVITIES; DOXORUBICIN; HUMAN CARCINOMA CELL LINE; HUMAN CARCINOMA CELLS; INTRAPERITONEAL INJECTIONS; NEPHROTOXICITY; QUERCETIN;

CELLS;

CASPASE 3; CATALASE; CREATININE; DOXORUBICIN; GLUTATHIONE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; MALONALDEHYDE; NITRIC OXIDE; QUERCETIN; TUMOR NECROSIS FACTOR ALPHA; ANTINEOPLASTIC AGENT; ANTIOXIDANT; NOS2 PROTEIN, HUMAN; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR;

APOPTOSIS; CANCER; CELLS AND CELL COMPONENTS; DRUG; ENVIRONMENTAL STRESS; ENZYME ACTIVITY; OXIDATION; RODENT; SECONDARY METABOLITE; SERUM; TOXICITY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMICAL ANALYSIS; CARCINOMA CELL; CELL VIABILITY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CYTOTOXICITY; DRUG POTENTIATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; KIDNEY FUNCTION TEST; MALE; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; UREA NITROGEN BLOOD LEVEL; ANIMAL; BLOOD; DRUG EFFECTS; GENETICS; HELA CELL LINE; HEP-G2 CELL LINE; IMMUNOHISTOCHEMISTRY; KIDNEY; MCF-7 CELL LINE; METABOLISM; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; TUMOR CELL LINE;

RATTUS;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; BLOOD UREA NITROGEN; CASPASE 3; CELL LINE, TUMOR; CREATININE; DOXORUBICIN; GLUTATHIONE; HELA CELLS; HEP G2 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1BETA; KIDNEY; MALE; MALONDIALDEHYDE; MCF-7 CELLS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; QUERCETIN; RATS; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84962868927     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.22075     Document Type: Article

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