Multicomponent analysis of the differential induction of secondary metabolite profiles in fungal endophytes

Molecules

Volumn 21, Issue 2, 2016, Pages

  González Menéndez, Víctor ^a   Pérez Bonilla, Mercedes ^a   Pérez Victoria, Ignacio ^a   Martín, Jesús ^a   Muñoz, Francisca ^a   Reyes, Fernando ^a   Tormo, José R ^a   Genilloud, Olga ^a  

^a Health Sciences Technology Park   (Spain)

Author keywords

DNMT; Epigenetic modifiers; Fungal endophytes; HDAC; Metabolomics; Secondary metabolites; Volcano plots

Indexed keywords

DNA (CYTOSINE 5) METHYLTRANSFERASE; ENZYME INHIBITOR; HISTONE DEACETYLASE INHIBITOR;

ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; DRUG EFFECTS; ENDOPHYTE; FUNGUS; GENE EXPRESSION REGULATION; METABOLISM; METABOLOMICS; MICROBIOLOGY; PLANT; SECONDARY METABOLISM;

BIOSYNTHETIC PATHWAYS; DNA-CYTOSINE METHYLASES; ENDOPHYTES; ENZYME INHIBITORS; FUNGI; GENE EXPRESSION REGULATION, FUNGAL; HISTONE DEACETYLASE INHIBITORS; METABOLOMICS; PLANTS; SECONDARY METABOLISM;

EID: 84962833472     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules21020234     Document Type: Article

References (29)

1. Xiang, S.; Liang-Dong, G. Endophytic fungal diversity: Review of traditional and molecular techniques. Mycology 2002, 3, 65-76.
2. Cichewicz, R.H. Epigenome manipulation as a pathway to new natural product scaffolds and their congeners. Nat. Prod. Rep. 2010, 27, 11-22. [CrossRef] [PubMed]
3. Brosch, G.; Loidl, P.; Graessle, S. Histone modifications and chromatin dynamics: A focus on filamentous fungi. Fems Microbiol. Rev. 2008, 32, 409-439. [CrossRef] [PubMed]
4. Preyat, N.; Leo, O. Sirtuin deacylases: A molecular link between metabolism and immunity. J. Leukoc. Biol. 2013, 93, 669-680. [CrossRef] [PubMed]
5. Avalos, J.L.; Bever, K.M.; Wolberger, C. Mechanism of sirtuin inhibition by nicotinamide: Altering the NAD(+) cosubstrate specificity of a Sir2 enzyme. Mol. Cell 2005, 18, 855-868. [CrossRef] [PubMed]
6. Moore, J.M.; Bradshaw, E.; Seipke, R.F.; Hutchings, M.I.; McArthur, M. Use and discovery of chemical elicitors that stimulate biosynthetic gene clusters in Streptomyces bacteria. Methods Enzymol. 2012, 517, 367-385. [PubMed]
7. Moskaug, J.O.; Carlsen, H.; Myhrstad, M.; Blomhoff, R. Molecular imaging of the biological effects of quercetin and quercetin-rich foods. Mech. Ageing Dev. 2004, 125, 315-324. [CrossRef] [PubMed]
8. Asai, T.; Morita, S.; Taniguchi, T.; Monde, K.; Oshima, Y. Epigenetic stimulation of polyketide production in Chaetomium cancroideum by an NAD(+)-dependent HDAC inhibitor. Org. Biomol. Chem. 2015, 14, 646-651. [CrossRef] [PubMed]
9. Vervoort, H.C.; Drašković, M.; Crews, P. Histone Deacetylase Inhibitors as a Tool to Up-regulate New Fungal Biosynthetic Products-Isolation of EGM-556, a Cyclodepsipeptide, from Microascus sp. Org. Lett. 2011, 13, 410-413. [CrossRef] [PubMed]
10. Beau, J.; Mahid, N.; Burda, W.N.; Harrington, L.; Shaw, L.N.; Mutka, T.; Kyle, D.E.; Barisic, B.; van Olphen, A.; Baker, B.J. Epigenetic Tailoring for the Production of Anti-Infective Cytosporones from the Marine Fungus Leucostoma persoonii. Mar. Drugs 2012, 10, 762-774. [CrossRef] [PubMed]
11. Chen, H.J.; Awakawa, T.; Sun, J.Y.; Wakimoto, T.; Abe, I. Epigenetic modifier-induced biosynthesis of novel fusaric acid derivatives in endophytic fungi from Datura stramonium L. Nat. Prod. Bioprospect. 2013, 3, 20-23. [CrossRef]
12. Albright, J.C.; Henke, M.T.; Soukup, A.A.; McClure, R.A.; Thomson, R.J.; Keller, N.P.; Kelleher, N.L. Large-scale metabolomics reveals a complex response of Aspergillus nidulans to epigenetic perturbation. ACS Chem. Biol. 2015, 10, 1535-1541. [CrossRef] [PubMed]
13. Hur, M.; Campbell, A.A.; Almeida-de-Macedo, M.; Li, L.; Ransom, N.; Jose, A.; Wurtele, E.S. A global approach to analysis and interpretation of metabolic data for plant natural product discovery. Nat. Prod. Rep. 2013, 30, 565-583. [CrossRef] [PubMed]
14. Bills, G.F.; González-Menéndez, V.; Platas, G. Kabatiella bupleuri sp. nov. (Dothideales), a pleomorphic epiphyte and endophyte of the Mediterranean plant Bupleurum gibraltarcum (Apiaceae). Mycologia. 2012, 104, 962-973. [CrossRef] [PubMed]
15. DelaCruz, M.; Martín, J.; González-Menéndez, V.; Pérez-Victoria, I.; Moreno, C.; Tormo, J.R.; El Aouad, N.; Guarro, J.; Vicente, F.; Reyes, F.; et al. Chemical and physical modulation of antibiotic activity in emericella species. Chem. Biodivers. 2012, 9, 1095-1113. [CrossRef] [PubMed]
16. Stanbury, P.F.; Whitakerm, A.; Hall, S.J. The isolation, preservation and improvement of industrially important microorganisms. In Principles of Fermentation Technology, 2nd ed.; Elsevier Science: Kidlington, UK, 1997; pp. 35-85.
17. Dhandhukia, P.C.; Thakkar, V.R. Standardization of growth and fermentation criteria of Lasiodiplodia theobromae for production of jasmonic acid. J. Biotechnol. 2007, 6, 707-712.
18. Leung, P.H.; Zhang, Q.X.; Wu, J.Y. Mycelium cultivation, chemical composition and antitumour activity of a Tolypocladium sp. fungus isolated from wild Cordyceps sinensis. J. Appl. Microbiol. 2006, 101, 275-283. [CrossRef] [PubMed]
19. Pirttilä, A.M.; Joensuu, P.; Pospiech, H.; Jalonen, J.; Hohtola, A. Bud endophytes of Scots pine produce adenine derivatives and other compounds that affect morphology and mitigate browning of callus cultures. Physiol. Plant. 2004, 121, 305-312. [CrossRef] [PubMed]
20. Gorbushina, A.A.; Whitehead, K.; Dornieden, T.; Niesse, A.; Schulte, A.; Hedges, J.I. Black fungal colonies as units of survival: Hyphal mycosporines synthesized by rock-dwelling microcolonial fungi. Can. J. Bot. 2003, 81, 131-138. [CrossRef]
21. Leach, C.M. Ultraviolet-absorbing substances associated with light-induced sporulation in fungi. Can. J. Bot. 1965, 43, 185-200. [CrossRef]
22. Trione, E.J.; Leach, C.M.; Mutch, J.T. Sporogenic substances isolated from fungi. Nature 1966, 212, 163-164. [CrossRef] [PubMed]
23. Young, V.J.; Patterson, A. UV protective compound from Glomerella cingulate a mycosporine. Phytochemistry 1982, 21, 1075-1077. [CrossRef]
24. Leite, B.; Nicholson, R.L. Mycosporine-alanine: A self-inhibitor of germination from the conidial mucilage of Colletotrichum graminicola. Exp. Mycol. 1992, 16, 76-86. [CrossRef]
25. Sommaruga, R.; Libkind, D.; van Broock, M.; Whitehead, K. Mycosporine-glutaminol-glucoside, a UV-absorbing compound of two Rhodotorula yeast species. Yeast 2004, 21, 1077-1081. [CrossRef] [PubMed]
26. Carreto, J.I.; Carignan, M.O. Mycosporine-like amino acids: Relevant secondary metabolites. Chemical and ecological aspects. Mar Drugs. 2011, 9, 387-446. [CrossRef] [PubMed]
27. Bills, G.F.; Platas, G.; Fillola, A.; Jiménez, M.R.; Collado, J.; Vicente, F.; Martín, J.; González, A.; Bur-Zimmermann, J.; Tormo, J.R.; et al. Enhancement of antibiotic and secondary metabolite detection from filamentous fungi by growth on nutritional arrays. J. Appl. Microbiol. 2008, 104, 1644-1658. [CrossRef] [PubMed]
28. González-Menéndez, V.; Asensio, F.; Moreno, C.; de Pedro, N.; Monteiro, M.C.; de la Cruz, M.; Vicente, F.; Bills, G.F.; Reyes, F.; Genilloud, O.; et al. Assessing the effects of adsorptive polymeric resin additions on fungal secondary metabolite chemical diversity. Mycology 2014, 5, 179-191. [CrossRef] [PubMed]
29. Cui, X.; Churchill, G.A. Statistical tests for differential expression in cDNA microarray experiments. Genome Biol. 2003, 4, 210. [CrossRef] [PubMed]