Clinical evidence of resveratrol bioactivity in cardiovascular disease

Current Opinion in Food Science

Volumn 8, Issue , 2016, Pages 68-73

  Bhullar, Khushwant S ^a   Udenigwe, Chibuike C ^b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b DALHOUSIE UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84962815727     PISSN: 22147993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cofs.2016.03.005     Document Type: Review

References (38)

1. Takaoka M. Resveratrol, a new phenolic compound, from Veratrum grandiflorum. Nippon Kagaku Kaishi 1939, 60:1090-1100.
2. Giovinazzo G., Ingrosso I., Paradiso A., De Gara L., Santino A. Resveratrol biosynthesis: plant metabolic engineering for nutritional improvement of food. Plant Foods Hum Nutr 2012, 67:191-199.
3. Mattivi F., Reniero F., Korhammer S. Isolation, characterization, and evolution in red wine vinification of resveratrol monomers. J Agric Food Chem 1995, 43:1820-1823.
4. Renaud S.D., de Lorgeril M. Wine, alcohol, platelets, and the French paradox for coronary heart disease. Lancet 1992, 339:1523-1526.
5. Go A.S., Mozaffarian D., Roger V.L., Benjamin E.J., Berry J.D., Blaha M.J., Fullerton H.J. Heart disease and stroke statistics - 2014 update. Circulation 2014, 129:e28-e292.
6. WHO (World Health Organization). (accessed on 23.02.16). http://www.who.int/cardiovascular_diseases/en/.
7. Sadruddin S., Arora R. Resveratrol: biologic and therapeutic implications. J Cardiometab Syndr 2009, 4:102-106.
8. WHO (World Health Organization) A global brief on hypertension: silent killer, global public health crisis. World 2015.
9. Bertelli A.A., Giovannini L., Giannessi D., Migliori M., Bernini W., Fregoni M., Bertelli A. Antiplatelet activity of synthetic and natural resveratrol in red wine. Int J Tissue React 1994, 17:1-3.
10. Sung M.M., Dyck J.R. Therapeutic potential of resveratrol in heart failure. Ann N Y Acad Sci 2015, 1348:32-45.
11. Movahed A., Nabipour I., Lieben Louis X., Thandapilly S.J., Yu L., Kalantarhormozi M., Rekabpour S.J., Netticadan T. Antihyperglycemic effects of short term resveratrol supplementation in type 2 diabetic patients. Evid Based Complement Alternat Med 2013, 10.1155/2013/851267.
12. Timmers S., Konings E., Bilet L., Houtkooper R.H., van de Weijer T., Goossens G.H., Moonen-Kornips E. Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. Cell Metab 2011, 14:612-622.
13. Soare A., Weiss E.P., Holloszy J.O., Fontana L. Multiple dietary supplements do not affect metabolic and cardiovascular health. Aging (Milano) 2014, 6:149-157.
14. Lamming D.W., Wood J.G., Sinclair D.A. MicroReview: small molecules that regulate lifespan: evidence for xenohormesis. Mol Microbiol 2004, 53:1003-1009.
15. Carrizzo A., Puca A., Damato A., Marino M., Franco E., Pompeo F., Vecchione C. Resveratrol improves vascular function in patients with hypertension and dyslipidemia by modulating NO metabolism. Hypertension 2013, 62:359-366.
16. Fujitaka K., Otani H., Jo F., Jo H., Nomura E., Iwasaki M., Das D.K. Modified resveratrol Longevinex improves endothelial function in adults with metabolic syndrome receiving standard treatment. Nutr Res 2011, 31:842-847.
17. Wong R.H., Berry N.M., Coates A.M., Buckley J.D., Bryan J., Kunz I., Howe P.R. Chronic resveratrol consumption improves brachial flow-mediated dilatation in healthy obese adults. J Hypertens 2013, 31:1819-1827.
18. Bhatt J.K., Thomas S., Nanjan M.J. Resveratrol supplementation improves glycemic control in type 2 diabetes mellitus. Nutr Res 2012, 32:537-541.
19. Tomé-Carneiro J., Larrosa M., González-Sarrías A., Tomás-Barberán F.A., Teresa Garcia-Conesa M., Carlos Espin J. Resveratrol and clinical trials: the crossroad from in vitro studies to human evidence. Curr Pharm Des 2013, 19:6064-6093.
20. Donnelly R., Davis K.R. Type 2 diabetes and atherosclerosis. Diabetes Obes Metab 2000, 2:S21-S30.
21. Bo S., Ciccone G., Castiglione A., Gambino R., De Michieli F., Villois P., Cassader M. Anti-inflammatory and antioxidant effects of resveratrol in healthy smokers a randomized, double-blind, placebo-controlled, cross-over trial. Curr Med Chem 2013, 20:1323-1331.
22. Tomé-Carneiro J., Gonzálvez M., Larrosa M., García-Almagro F.J., Avilés-Plaza F., Parra S., Espín J.C. Consumption of a grape extract supplement containing resveratrol decreases oxidized LDL and ApoB in patients undergoing primary prevention of cardiovascular disease: a triple-blind, 6-month follow-up, placebo-controlled, randomized trial. Mol Nutr Food Res 2012, 56:810-821.
23. Militaru C., Donoiu I., Craciun A., Scorei I.D., Bulearca A.M., Scorei R.I. Oral resveratrol and calcium fructoborate supplementation in subjects with stable angina pectoris: Effects on lipid profiles, inflammation markers, and quality of life. Nutrition 2013, 29:178-183.
24. Yoshino J., Conte C., Fontana L., Mittendorfer B., Imai S.I., Schechtman K.B., Klein S. Resveratrol supplementation does not improve metabolic function in nonobese women with normal glucose tolerance. Cell Metab 2012, 16:658-664.
25. Poulsen M.M., Vestergaard P.F., Clasen B.F., Radko Y., Christensen L.P., Stødkilde-Jørgensen H., Jørgensen J.O.L. High-dose resveratrol supplementation in obese men an investigator-initiated, randomized, placebo-controlled clinical trial of substrate metabolism, insulin sensitivity, and body composition. Diabetes 2013, 62:1186-1195.
26. Sahebkar A. Effects of resveratrol supplementation on plasma lipids: a systematic review and meta-analysis of randomized controlled trials. Nutr Rev 2013, 71:822-835.
27. Tomé-Carneiro J., Gonzálvez M., Larrosa M., Yáñez-Gascón M.J., García-Almagro F.J., Ruiz-Ros J.A., Espín J.C. Grape resveratrol increases serum adiponectin and downregulates inflammatory genes in peripheral blood mononuclear cells: a triple-blind, placebo-controlled, one-year clinical trial in patients with stable coronary artery disease. Cardiovasc Drug Ther 2013, 27:37-48.
28. Magyar K., Halmosi R., Palfi A., Feher G., Czopf L., Fulop A., Szabados E. Cardioprotection by resveratrol: a human clinical trial in patients with stable coronary artery disease. Clin Hemorheol Microcirc 2012, 50:179-187.
29. Semba R.D., Ferrucci L., Bartali B., Urpí-Sarda M., Zamora-Ros R., Sun K., Andres-Lacueva C. Resveratrol levels and all-cause mortality in older community-dwelling adults. JAMA Intern Med 2014, 174:1077-1084.
30. Gliemann L., Schmidt J.F., Olesen J., Biensø R.S., Peronard S.L., Grandjean S.U., Hellsten Y. Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men. J Physiol 2013, 591:5047-5059.
31. Cottart C.H., Nivet-Antoine V., Laguillier-Morizot C., Beaudeux J.L. Resveratrol bioavailability and toxicity in humans. Mol Nutr Food Res 2010, 54:7-16.
32. Russell R.M. Factors in aging that effect the bioavailability of nutrients. J Nutr 2001, 131:1359S-1361S.
33. Agarwal B., Campen M.J., Channell M.M., Wherry S.J., Varamini B., Davis J.G., Smoliga J.M. Resveratrol for primary prevention of atherosclerosis: clinical trial evidence for improved gene expression in vascular endothelium. Int J Cardiol 2013, 166:246-248.
34. Bresciani L., Calani L., Bocchi L., Delucchi F., Savi M., Ray S., Del Rio D. Bioaccumulation of resveratrol metabolites in myocardial tissue is dose-time dependent and related to cardiac hemodynamics in diabetic rats. Nutr Metab Cardiovasc Dis 2014, 24:408-415.
35. Augustin M.A., Sanguansri L., Lockett T. Nano- and micro-encapsulated systems for enhancing the delivery of resveratrol. Ann N Y Acad Sci 2013, 1290:107-112.
36. Sessa M., Balestrieri M.L., Ferrari G., Servillo L., Castaldo D., D'Onofrio N., Tsao R. Bioavailability of encapsulated resveratrol into nanoemulsion-based delivery systems. Food Chem 2014, 147:42-50.
37. Udenigwe C.C., Ramprasath V.R., Aluko R.E., Jones P.J. Potential of resveratrol in anticancer and anti-inflammatory therapy. Nutr Rev 2008, 66:445-454.
38. Chow H.S., Garland L.L., Hsu C.H., Vining D.R., Chew W.M., Miller J.A., Alberts D.S. Resveratrol modulates drug-and carcinogen-metabolizing enzymes in a healthy volunteer study. Cancer Prev Res 2010, 3:1168-1175.