Chronic resveratrol consumption improves brachial flow-mediated dilatation in healthy obese adults

Journal of Hypertension

Volumn 31, Issue 9, 2013, Pages 1819-1827

  Wong, Rachel H X ^a   Berry, Narelle M ^a   Coates, Alison M ^a   Buckley, Jonathan D ^a   Bryan, Janet ^a   Kunz, Iris ^b   Howe, Peter R C ^a,c  

^a UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^b DSM NUTRITIONAL PRODUCTS LTD   (Switzerland)

^c UNIVERSITY OF NEWCASTLE   (Australia)

Author keywords

Bioactive nutrients; Cognition; Flow mediated dilatation; Obesity; Resveratrol; Vascular function

Indexed keywords

PLACEBO; RESVERATROL; RESVIDA; UNCLASSIFIED DRUG;

ABSENCE OF SIDE EFFECTS; ADULT; AGED; ARTERY COMPLIANCE; ARTERY DILATATION; ARTICLE; BLOOD PRESSURE; BRAIN BLOOD FLOW; CLINICAL ARTICLE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; DRUG TOLERABILITY; DRUG USE; FEMALE; FLOW MEDIATED DILATATION; HUMAN; LONG TERM CARE; MALE; MEDICATION COMPLIANCE; OBESITY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; TREATMENT DURATION; VEGETARIAN DIET;

ADULT; AGED; BLOOD FLOW VELOCITY; BLOOD PRESSURE; BLOOD PRESSURE MONITORING, AMBULATORY; BODY MASS INDEX; BRACHIAL ARTERY; CAROTID ARTERIES; CROSS-OVER STUDIES; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; MALE; MIDDLE AGED; OBESITY; OVERWEIGHT; POSTMENOPAUSE; QUESTIONNAIRES; STILBENES; STROOP TEST; VASODILATION;

EID: 84950170739     PISSN: 02636352     EISSN: 14735598     Source Type: Journal    
DOI: 10.1097/HJH.0b013e328362b9d6     Document Type: Article

References (33)

1. Yavuz BB, Yavuz B, Sener D.D., Cankurtaran M., Halil M, Ulger Z, et al. Advanced age is associated with endothelial dysfunction in healthy elderly subjects. Gerontology 2008; 54:153-156.
2. Davison K, Bircher S, Hill A., Coates AM, Howe PR, Buckley JD. Relationships between obesity cardiorespiratory fitness and cardiovascular function. J Obes 2010; 2010:191253.
3. Forman DE, Cohen RA, Hoth K.F., Haley AP, Poppas A, Moser DJ, et al. Vascular health and cognitive function in older adults with cardiovascular disease. Art Res 2008; 2:35-43.
4. Silvestrini M, Pasqualetti P, Baruffaldi R., Bartolini M, Handouk Y, Matteis M., et al. Cerebrovascular reactivity and cognitive decline in patients with Alzheimer disease. Stroke 2006; 37:1010-1015.
5. Sinn N, Howe PRC. Mental health benefits of omega-3 fatty acids may be mediated by improvements in cerebral vascular function. Biosci Hypoth 2008; 1:103-108.
6. Vang O, Ahmad N, Baile C.A., Baur JA, Brown K, Csiszar A, et al. What is new for an old molecule? Systematic review and recommendations on the use of resveratrol. PLoS One 2011; 6:e19881.
7. Chachay VS, Kirkpatrick CM, Hickman I.J., Ferguson M., Prins JB, Martin JH Resveratrol: pills to replace a healthy diet? Br J Clin Pharmacol 2011; 72:27-38.
8. Lekakis J, Rallidis LS, Andreadou I, Vamvakou G., Kazantzoglou G, Magiatis P, et al. Polyphenolic compounds from red grapes acutely improve endothelial function in patients with coronary heart disease. Eur J Cardiovasc Prev Rehabil 2005; 12:596-600.
9. Clifton PM. Effect of grape seed extract and quercetin on cardiovascular and endothelial parameters in high-risk subjects. J Biomed Biotechnol 2004; 2004:272-278.
10. Mellen PB, Daniel KR, Brosnihan K.B., Hansen KJ, Herrington DM. Effect of muscadine grape seed supplementation on vascular function in subjects with or at risk for cardiovascular disease: a randomized crossover trial. J Am Coll Nutr 2010; 29:469-475.
11. Wong RHX, Howe PRC, Buckley JD, Coates A.M., Kunz I., Berry NM. Acute resveratrol supplementation improves flow-mediated dilatation in overweight/obese individuals with mildly elevated blood pressure. Nutr Metab Cardiovasc Dis 2011; 21:851-856.
12. Kennedy DO, Wightman EL, Reay J.L., Lietz G., Okello EJ, Wilde A, Haskell CF. Effects of resveratrol on cerebral blood flow variables and cognitive performance in humans: a double-blind placebo-controlled crossover investigation. Am J Clin Nutr 2010; 91:1590-1597.
13. Schoenfeld D. Web based program for computing various sample sizes: Sample Size Program, 2011, Massachusetts General Hospital Biostatistics Center. Available online: http://hedwig.mgh.harvard.edu/sample-size/js/js-crossover- quant.html (Accessed 01 December 2011)
14. Chobanian AV, Bakris GL, Black H.R., Cushman WC, Green LA, Izzo JL Jr, et al. Seventh report of the Joint National Committee on Prevention Detection Evaluation and Treatment of High Blood Pressure. Hypertension 2003; 42:1206-1252.
15. Harris RA, Nishiyama SK, Wray D.W., Richardson RS Ultrasound assessment of flow-mediated dilation. Hypertension 2010; 55:1075-1085.
16. Thijssen DHJ, Black MA, Pyke K.E., Padilla J., Atkinson G, Harris RA, et al. Assessment of flow-mediated dilation in humans: a methodological and physiological guideline. Am J Physiol Heart Circ Physiol 2011; 300:H2-H12.
17. Strauss E. A compendium of neuropsychological tests: administration norms and commentary, 3rd ed. Oxford: Oxford University Press; 2006; pp. 477-499.
18. Berry NM, Robinson MJ, Bryan J, Buckley J.D., Murphy KJ, Howe PRC. Acute effects of an Avena sativa herb extract on responses to the Stroop Color-Word Test. J Evid Based Complementary Altern Med 2011; 17:635-637.
19. Dodrill CB. A neuropsychological battery for epilepsy. Epilepsia 1978; 19:611-623.
20. West SG, Wagner P, Schoemer S.L., Hecker KD, Hurston KL, Likos Krick A, et al. Biological correlates of day-to-day variation in flow-mediated dilation in individuals with type 2 diabetes: a study of test-retest reliability. Diabetologia 2004; 47:1625-1631.
21. Davison K, Coates AM, Buckley J.D., Howe PR. Effect of cocoa flavanols and exercise on cardiometabolic risk factors in overweight and obese subjects. Int J Obes (Lond) 2008; 32:1289-1296.
22. Fujitaka K, Otani H, Jo F., Jo H, Nomura E, Iwasaki M., et al. Modified resveratrol Longevinex improves endothelial function in adults with metabolic syndrome receiving standard treatment. Nutr Res 2011; 31:842-847.
23. Kim SM, Rico CW, Lee S.C., Kang MY. Modulatory effect of rice bran and phytic acid on glucose metabolism in high fat-fed C57BL/6N mice. J Clin Biochem Nutr 2010; 47:12-17.
24. Harris RA, Pedersen-White J, Guo D.H., Stallmann-Jorgensen IS, Keeton D, Huang Y., et al. Vitamin D3 supplementation for 16 weeks improves flow-mediated dilation in overweight African-American adults. Am J Hypertens 2011; 24:557-562.
25. Magyar K, Halmosi R, Palfi A., Feher G, Czopf L, Fulop A., et al. Cardioprotection by resveratrol: a human clinical trial in patients with stable coronary artery disease. Clin Hemorheol Microcirc 2012; 50:179-187.
26. Almeida L, Vaz-da-Silva M, Falcao A, Soares E, Costa R, Loureiro AI, et al. Pharmacokinetic and safety profile of trans-resveratrol in a rising multiple-dose study in healthy volunteers. Mol Nutr Food Res 2009; 53 (SUPPL. 1):S7-15.
27. Hooper L, Kroon PA, Rimm E.B., Cohn JS, Harvey I, Le Cornu KA, et al. Flavonoids flavonoid-rich foods and cardiovascular risk: a meta-analysis of randomized controlled trials. Am J Clin Nutr 2008; 88:38-50.
28. Carlo Agostoni, Jean-Louis Bresson, Fairweather-Tait SJ, Albert Flynn, Ines Golly, Hannu Korhonen, et al., EFSA, P.o.D.P. Scientific Opinion on the substantiation of a health claim related to cocoa flavanols and maintenance of normal endothelium-dependent vasodilation pursuant to Article 13(5) of Regulation (EC) No 1924/2006. EFSA J 2012; 10:2809.
29. Celermajer DS, Sorensen KE, Bull C, Robinson J., Deanfield JE. Endothelium-dependent dilation in the systemic arteries of asymptomatic subjects related to coronary risk-factors and their interaction. J Am Coll Cardiol 1994; 24:1468-1474.
30. Inaba Y, Chen JA, Bergmann SR. Prediction of future cardiovascular outcomes by flow-mediated vasodilatation of brachial artery: a meta-analysis. Int J Cardiovasc Imaging 2010; 26:631-640.
31. Desideri G, Kwik-Uribe C, Grassi D., Necozione S, Ghiadoni L, Mastroiacovo D., et al. Benefits in cognitive function blood pressure and insulin resistance through cocoa flavanol consumption in elderly subjects with mild cognitive impairment: the Cocoa, Cognition and Aging (CoCoA) study. Hypertension 2012; 60:794-801.
32. Li H, Xia N, Förstermann U. Cardiovascular effects and molecular targets of resveratrol. Nitric Oxide 2012; 26:102-110.
33. Neveu V, Perez-Jimenez J, Vos F., Crespy V, du Chaffaut L, Mennen L, et al. Phenol-Explorer: an online comprehensive database on polyphenol contents in foods. Database (Oxford) 2010; 2010:ba024.