Evaluation of type 2 diabetes genetic risk variants in Chinese adults: findings from 93,000 individuals from the China Kadoorie Biobank

Diabetologia

Volumn 59, Issue 7, 2016, Pages 1446-1457

  Gan, Wei ^a,b   Walters, Robin G ^c   Holmes, Michael V ^c   Bragg, Fiona ^c   Millwood, Iona Y ^c   Banasik, Karina ^a,b,d   Chen, Yiping ^c   Du, Huaidong ^c   Iona, Andri ^c   Mahajan, Anubha ^a,b   Yang, Ling ^c   Bian, Zheng ^e   Guo, Yu ^e   Clarke, Robert J ^c   Li, Liming ^e,f   McCarthy, Mark I ^a,b,g   Chen, Zhengming ^c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d Capital Region   (Denmark)

^e PEKING UNION MEDICAL COLLEGE   (China)

^f PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^g NIHR OXFORD BIOMEDICAL RESEARCH CENTRE   (United Kingdom)

Author keywords

Biobank; Chinese; Genetic risk score; Population based cohort studies; Type 2 diabetes; Winner s curse

Indexed keywords

ADCY5 PROTEIN; NOTCH2 RECEPTOR; PRC1 PROTEIN; PROTEIN; THADA PROTEIN; TRANSCRIPTION FACTOR 7 LIKE 2; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BODY MASS; CHINESE; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENE LOCUS; GENE STRUCTURE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETIC RISK; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; ASIAN CONTINENTAL ANCESTRY GROUP; BIOBANK; CHINA; DIABETES MELLITUS, TYPE 2; GENETICS; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; MIDDLE AGED; PHYSIOLOGY; WAIST CIRCUMFERENCE;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; BIOLOGICAL SPECIMEN BANKS; CHINA; DIABETES MELLITUS, TYPE 2; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; WAIST CIRCUMFERENCE;

EID: 84962658983     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-016-3920-9     Document Type: Article

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