Quantifying the Area at Risk in Reperfused ST-Segment-Elevation Myocardial Infarction Patients Using Hybrid Cardiac Positron Emission Tomography-Magnetic Resonance Imaging

Circulation: Cardiovascular Imaging

Volumn 9, Issue 3, 2016, Pages

  Bulluck, Heerajnarain ^a,b   White, Steven K ^a,b   Fröhlich, Georg M ^a   Casson, Steven G ^b   O'Meara, Celia ^b   Newton, Ayla ^a   Nicholas, Jennifer ^c   Weale, Peter ^d   Wan, Simon M Y ^b   Sirker, Alex ^b   Moon, James C ^b   Yellon, Derek M ^a,b   Groves, Ashley ^b   Menezes, Leon ^b   Hausenloy, Derek J ^a,b,e,f  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

^c LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^d Caernarfon   (United Kingdom)

^e NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^f DEPARTMENT OF CARDIOLOGY   (Singapore)

Author keywords

area at risk; cardiovascular magnetic resonance imaging; F flurodeoxyglucose; hybrid PET MR imaging; infarct size; positron emission tomography; ST segment elevation myocardial infarction; T2 mapping; viability

Indexed keywords

FLUORODEOXYGLUCOSE F 18; GADOTERATE MEGLUMINE; CONTRAST MEDIUM; GADOLINIUM 1,4,7,10-TETRAAZACYCLODODECANE-N,N',N'',N'''-TETRAACETATE; HETEROCYCLIC COMPOUND; ORGANOMETALLIC COMPOUND; RADIOPHARMACEUTICAL AGENT;

ADULT; ARTICLE; CLINICAL ARTICLE; FEMALE; FOLLOW UP; GLUCOSE TRANSPORT; HEART MUSCLE; HUMAN; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PERCUTANEOUS CORONARY INTERVENTION; PET-MRI SCANNER; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; AGED; CARDIAC MUSCLE; CINE MAGNETIC RESONANCE IMAGING; COMPUTER ASSISTED DIAGNOSIS; CONVALESCENCE; CORONARY ARTERY BLOOD FLOW; DIAGNOSTIC IMAGING; METABOLISM; MIDDLE AGED; MULTIMODAL IMAGING; MYOCARDIAL INFARCTION; MYOCARDIAL PERFUSION IMAGING; PATHOLOGY; PATHOPHYSIOLOGY; PREDICTIVE VALUE; PROCEDURES; TIME FACTOR; TISSUE SURVIVAL; TREATMENT OUTCOME;

AGED; CONTRAST MEDIA; CORONARY CIRCULATION; FEMALE; FLUORODEOXYGLUCOSE F18; HETEROCYCLIC COMPOUNDS; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING, CINE; MALE; MIDDLE AGED; MULTIMODAL IMAGING; MYOCARDIAL INFARCTION; MYOCARDIAL PERFUSION IMAGING; MYOCARDIUM; ORGANOMETALLIC COMPOUNDS; PERCUTANEOUS CORONARY INTERVENTION; POSITRON-EMISSION TOMOGRAPHY; PREDICTIVE VALUE OF TESTS; RADIOPHARMACEUTICALS; RECOVERY OF FUNCTION; TIME FACTORS; TISSUE SURVIVAL; TREATMENT OUTCOME;

EID: 84962623515     PISSN: 19419651     EISSN: 19420080     Source Type: Journal    
DOI: 10.1161/CIRCIMAGING.115.003900     Document Type: Article

References (35)

1. Friedrich MG, Abdel-Aty H, Taylor A, Schulz-Menger J, Messroghli D, Dietz R., The salvaged area at risk in reperfused acute myocardial infarction as visualized by cardiovascular magnetic resonance. J Am Coll Cardiol 2008 51 1581 1587. doi: 10.1016/j.jacc.2008.01.019
2. Carlsson M, Ubachs JF, Hedström E, Heiberg E, Jovinge S, Arheden H., Myocardium at risk after acute infarction in humans on cardiac magnetic resonance: quantitative assessment during follow-up and validation with single-photon emission computed tomography. JACC Cardiovasc Imaging 2009 2 569 576. doi: 10.1016/j.jcmg.2008.11.018
3. White SK, Hausenloy DJ, Moon JC., Imaging the myocardial microcirculation post-myocardial infarction. Curr Heart Fail Rep 2012 9 282 292. doi: 10.1007/s11897-012-0111-y
4. Betgem RP, de Waard GA, Nijveldt R, Beek AM, Escaned J, van Royen N., Intramyocardial haemorrhage after acute myocardial infarction. Nat Rev Cardiol 2015 12 156 167. doi: 10.1038/nrcardio.2014.188
5. Schlosser T, Nensa F, Mahabadi AA, Poeppel TD., Hybrid MRI/PET of the heart: a new complementary imaging technique for simultaneous acquisition of MRI and PET data. Heart 2013 99 351 352. doi: 10.1136/heartjnl-2012-302740
6. Nensa F, Poeppel TD, Beiderwellen K, Schelhorn J, Mahabadi AA, Erbel R, Heusch P, Nassenstein K, Bockisch A, Forsting M, Schlosser T., Hybrid PET/MR imaging of the heart: feasibility and initial results. Radiology 2013 268 366 373. doi: 10.1148/radiol.13130231
7. Rischpler C, Nekolla SG, Dregely I, Schwaiger M., Hybrid PET/MR imaging of the heart: potential, initial experiences, and future prospects. J Nucl Med 2013 54 402 415. doi: 10.2967/jnumed.112.105353
8. Rischpler C, Langwieser N, Souvatzoglou M, Batrice A, van Marwick S, Snajberk J, Ibrahim T, Laugwitz KL, Nekolla SG, Schwaiger M., PET/MRI early after myocardial infarction: evaluation of viability with late gadolinium enhancement transmurality vs. 18F-FDG uptake. Eur Heart J Cardiovasc Imaging 2015 16 661 669. doi: 10.1093/ehjci/jeu317
9. White SK, Frohlich GM, Sado DM, Maestrini V, Fontana M, Treibel TA, Tehrani S, Flett AS, Meier P, Ariti C, Davies JR, Moon JC, Yellon DM, Hausenloy DJ., Remote ischemic conditioning reduces myocardial infarct size and edema in patients with ST-segment elevation myocardial infarction. JACC Cardiovasc Interv 2015 8 1 pt B 178 188. doi: 10.1016/j.jcin.2014.05.015
10. Bøtker HE, Kaltoft AK, Pedersen SF, Kim WY., Measuring myocardial salvage. Cardiovasc Res 2012 94 266 275. doi: 10.1093/cvr/cvs081
11. Nensa F, Poeppel T, Tezgah E, Heusch P, Nassenstein K, Mahabadi AA, Forsting M, Bockisch A, Erbel R, Heusch G, Schlosser T., Integrated FDG PET/MR imaging for the assessment of myocardial salvage in reperfused acute myocardial infarction. Radiology 2015 140564
12. Machac J, Bacharach SL, Bateman TM, Bax JJ, Beanlands R, Bengel F, Bergmann SR, Brunken RC, Case J, Delbeke D, DiCarli MF, Garcia EV, Goldstein RA, Gropler RJ, Travin M, Patterson R, Schelbert HR, Quality Assurance Committee of the American Society of Nuclear Cardiology Positron emission tomography myocardial perfusion and glucose metabolism imaging. J Nucl Cardiol 2006 13 e121 e151. doi: 10.1016/j.nuclcard.2006.08.009
13. Kramer CM, Barkhausen J, Flamm SD, Kim RJ, Nagel E, Society for Cardiovascular Magnetic Resonance Board of Trustees Task Force on Standardized Protocols Standardized cardiovascular magnetic resonance imaging (CMR) protocols, society for cardiovascular magnetic resonance: board of trustees task force on standardized protocols. J Cardiovasc Magn Reson 2008 10 35. doi: 10.1186/1532-429X-10-35
14. Giri S, Chung YC, Merchant A, Mihai G, Rajagopalan S, Raman SV, Simonetti OP., T2 quantification for improved detection of myocardial edema. J Cardiovasc Magn Reson 2009 11 56. doi: 10.1186/1532-429X-11-56
15. Martinez-Möller A, Souvatzoglou M, Delso G, Bundschuh RA, Chefd'hotel C, Ziegler SI, Navab N, Schwaiger M, Nekolla SG., Tissue classification as a potential approach for attenuation correction in whole-body PET/MRI: evaluation with PET/CT data. J Nucl Med 2009 50 520 526. doi: 10.2967/jnumed.108.054726
16. Baer FM, Voth E, Deutsch HJ, Schneider CA, Horst M, de Vivie ER, Schicha H, Erdmann E, Sechtem U., Predictive value of low dose dobutamine transesophageal echocardiography and fluorine-18 fluorodeoxyglucose positron emission tomography for recovery of regional left ventricular function after successful revascularization. J Am Coll Cardiol 1996 28 60 69
17. Cerqueira MD, Weissman NJ, Dilsizian V, Jacobs AK, Kaul S, Laskey WK, Pennell DJ, Rumberger JA, Ryan T, Verani MS, American Heart Association Writing Group on Myocardial Segmentation and Registration for Cardiac Imaging Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart. A statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association. Int J Cardiovasc Imaging 2002 18 539 542
18. Kim RJ, Wu E, Rafael A, Chen EL, Parker MA, Simonetti O, Klocke FJ, Bonow RO, Judd RM., The use of contrast-enhanced magnetic resonance imaging to identify reversible myocardial dysfunction. N Engl J Med 2000 343 1445 1453. doi: 10.1056/NEJM200011163432003
19. Ortiz-Pérez JT, Meyers SN, Lee DC, Kansal P, Klocke FJ, Holly TA, Davidson CJ, Bonow RO, Wu E., Angiographic estimates of myocardium at risk during acute myocardial infarction: validation study using cardiac magnetic resonance imaging. Eur Heart J 2007 28 1750 1758. doi: 10.1093/eurheartj/ehm212
20. Shrout PE, Fleiss JL., Intraclass correlations: uses in assessing rater reliability. Psychol Bull 1979 86 420 428
21. DeLong ER, DeLong DM, Clarke-Pearson DL., Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics 1988 44 837 845
22. Hinkle DE, Wiersma W, Jurs SG., Applied Statistics for the Behavioral Sciences 1998 4th ed Boston Houghton Mifflin Company
23. McAlindon EJ, Pufulete M, Harris JM, Lawton CB, Moon JC, Manghat N, Hamilton MC, Weale PJ, Bucciarelli-Ducci C., Measurement of myocardium at risk with cardiovascular MR: comparison of techniques for edema imaging. Radiology 2015 275 61 70. doi: 10.1148/radiol.14131980
24. Aletras AH, Tilak GS, Natanzon A, Hsu LY, Gonzalez FM, Hoyt RF Jr, Arai AE., Retrospective determination of the area at risk for reperfused acute myocardial infarction with T2-weighted cardiac magnetic resonance imaging: histopathological and displacement encoding with stimulated echoes (DENSE) functional validations. Circulation 2006 113 1865 1870. doi: 10.1161/CIRCULATIONAHA.105.576025
25. Ibanez B, Prat-González S, Speidl WS, Vilahur G, Pinero A, Cimmino G, García MJ, Fuster V, Sanz J, Badimon JJ., Early metoprolol administration before coronary reperfusion results in increased myocardial salvage: analysis of ischemic myocardium at risk using cardiac magnetic resonance. Circulation 2007 115 2909 2916. doi: 10.1161/CIRCULATIONAHA.106.679639
26. Berry C, Kellman P, Mancini C, Chen MY, Bandettini WP, Lowrey T, Hsu LY, Aletras AH, Arai AE., Magnetic resonance imaging delineates the ischemic area at risk and myocardial salvage in patients with acute myocardial infarction. Circ Cardiovasc Imaging 2010 3 527 535. doi: 10.1161/CIRCIMAGING.109.900761
27. Langhans B, Nadjiri J, Jähnichen C, Kastrati A, Martinoff S, Hadamitzky M., Reproducibility of area at risk assessment in acute myocardial infarction by T1-and T2-mapping sequences in cardiac magnetic resonance imaging in comparison to Tc99m-sestamibi SPECT. Int J Cardiovasc Imaging 2014 30 1357 1363. doi: 10.1007/s10554-014-0467-z
28. Fuernau G, Eitel I, Franke V, Hildebrandt L, Meissner J, de Waha S, Lurz P, Gutberlet M, Desch S, Schuler G, Thiele H., Myocardium at risk in ST-segment elevation myocardial infarction comparison of T2-weighted edema imaging with the MR-assessed endocardial surface area and validation against angiographic scoring. JACC Cardiovasc Imaging 2011 4 967 976. doi: 10.1016/j.jcmg.2011.02.023.4
29. Schwaiger M, Schelbert HR, Ellison D, Hansen H, Yeatman L, Vinten-Johansen J, Selin C, Barrio J, Phelps ME., Sustained regional abnormalities in cardiac metabolism after transient ischemia in the chronic dog model. J Am Coll Cardiol 1985 6 336 347
30. Buxton DB, Mody FV, Krivokapich J, Phelps ME, Schelbert HR., Quantitative assessment of prolonged metabolic abnormalities in reperfused canine myocardium. Circulation 1992 85 1842 1856
31. McFalls EO, Baldwin D, Marx D, Fashingbauer P, Ward H., Temporal changes in function and regional glucose uptake within stunned porcine myocardium. J Nucl Med 1996 37 2006 2010
32. Hacker TA, Renstrom B, Nellis SH, Liedtke AJ., Effect of repetitive stunning on myocardial metabolism in pig hearts. Am J Physiol 1997 273 3 Pt 2 H1395 H1402
33. Di Carli MF, Prcevski P, Singh TP, Janisse J, Ager J, Muzik O, Vander Heide R., Myocardial blood flow, function, and metabolism in repetitive stunning. J Nucl Med 2000 41 1227 1234
34. Shirasaki H, Nakano A, Uzui H, Yonekura Y, Okazawa H, Ueda T, Lee JD., Comparative assessment of 18F-fluorodeoxyglucose PET and 99mTc-tetrofosmin SPECT for the prediction of functional recovery in patients with reperfused acute myocardial infarction. Eur J Nucl Med Mol Imaging 2006 33 879 886. doi: 10.1007/s00259-006-0071-0
35. Wu KC., CMR of microvascular obstruction and hemorrhage in myocardial infarction. J Cardiovasc Magn Reson 2012 14 68. doi: 10.1186/1532-429X-14-68