Influence of agglomeration and specific lung lining lipid/protein interaction on short-term inhalation toxicity

Nanotoxicology

Volumn 10, Issue 7, 2016, Pages 970-980

  Wohlleben, Wendel ^a   Driessen, Marc D ^b   Raesch, Simon ^c   Schaefer, Ulrich F ^c   Schulze, Christine ^c   Vacano, Bernhard von ^a   Vennemann, Antje ^d   Wiemann, Martin ^d   Ruge, Christian A ^c   Platsch, Herbert ^a   Mues, Sarah ^e   Ossig, Rainer ^e   Tomm, Janina M ^f   Schnekenburger, Jürgen ^e   Kuhlbusch, Thomas A J ^g,h   Luch, Andreas ^b   Lehr, Claus Michael ^c,i   Haase, Andrea ^b  

^a BASF SE   (Germany)

^b FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

^c SAARLAND UNIVERSITY   (Germany)

^d IBE R and D gGmbH   (Germany)

^e UNIVERSITY OF MÜNSTER   (Germany)

^f HELMHOLTZ CENTRE FOR ENVIRONMENTAL RESEARCH UFZ   (Germany)

^g Institute of Energy and Environmental Technology EV (IUTA)   (Germany)

^h UNIVERSITY OF DUISBURG ESSEN   (Germany)

ⁱ HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

Lipid corona; lung surfactant; protein corona; silica nanoparticles; surface functionalization

Indexed keywords

DEIONIZED WATER; LUNG SURFACTANT; PHOSPHATE; PORACTANT; PROTEIN CORONA; SERUM ALBUMIN; SILICON DIOXIDE; BIOLOGICAL PRODUCT; NANOPARTICLE; PHOSPHOLIPID; PLASMA PROTEIN; PROTEIN; PROTEIN BINDING; ZIRCONIUM; ZIRCONIUM OXIDE;

ANIMAL TISSUE; ARTICLE; BILAYER MEMBRANE; BINDING KINETICS; CENTRIFUGATION; CONTROLLED STUDY; DISPERSION; HYDROPHILICITY; HYDROPHOBICITY; IN VITRO STUDY; LIPID BILAYER; LIPID COMPOSITION; LIPID VESICLE; LUNG BURDEN; MASS SPECTROMETRY; NONHUMAN; PARTICLE SIZE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PREDICTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LIPID INTERACTION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SURFACE AREA; SURFACE CHARGE; SURFACE PROPERTY; ZETA POTENTIAL; ADVERSE EFFECTS; ANIMAL; BIOLOGICAL MODEL; BRONCHOALVEOLAR LAVAGE FLUID; CHEMICAL PHENOMENA; CHEMISTRY; DRUG EFFECTS; EXPOSURE; ISOLATION AND PURIFICATION; LUNG; METABOLISM; PIG;

ANIMALS; BIOLOGICAL PRODUCTS; BLOOD PROTEINS; BRONCHOALVEOLAR LAVAGE FLUID; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; INHALATION EXPOSURE; LUNG; MODELS, BIOLOGICAL; NANOPARTICLES; PARTICLE SIZE; PHOSPHOLIPIDS; PROTEIN BINDING; PROTEIN CORONA; PROTEINS; PULMONARY SURFACTANTS; SILICON DIOXIDE; SURFACE PROPERTIES; SWINE; ZIRCONIUM;

EID: 84962615871     PISSN: 17435390     EISSN: 17435404     Source Type: Journal    
DOI: 10.3109/17435390.2016.1155671     Document Type: Article

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