Identification of IL-23p19 as an endothelial proinflammatory peptide that promotes gp130-STAT3 signaling

Science Signaling

Volumn 9, Issue 419, 2016, Pages

  Espígol Frigolé, Georgina ^a,b   Planas Rigol, Ester ^a,b   Ohnuki, Hidetaka ^a   Salvucci, Ombretta ^a   Kwak, Hyeongil ^a   Ravichandran, Sarangan ^c   Luke, Brian ^c   Cid, Maria C ^b   Tosato, Giovanna ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF BARCELONA   (Spain)

^c FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD31 ANTIGEN; CXCL11 CHEMOKINE; CXCL9 CHEMOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLYCOPROTEIN GP 130; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 12 RECEPTOR; INTERLEUKIN 12P40; INTERLEUKIN 1BETA; INTERLEUKIN 23; INTERLEUKIN 23P19; INTERLEUKIN 23P40; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; PROTEIN P19; PROTEIN P40; STAT1 PROTEIN; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; AUTACOID; ICAM1 PROTEIN, HUMAN; IL23A PROTEIN, HUMAN; STAT3 PROTEIN, HUMAN;

ADVENTITIA; AGED; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL WALL; CELL DENSITY; CELL LEVEL; CELL STIMULATION; CELL SURFACE; CONTROLLED STUDY; DERMAL MICROVASCULAR ENDOTHELIAL CELL; DISEASE ASSOCIATION; ENZYME REGULATION; GENETIC TRANSCRIPTION; GIANT CELL ARTERITIS; HUMAN; HUMAN CELL; INFLAMMATION; INTIMA; LEUKOCYTE; LEUKOCYTE ADHERENCE; MICROENVIRONMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; STABLE EXPRESSION; SUPERFICIAL TEMPORAL ARTERY; TISSUE LEVEL; TRANSCRIPTION INITIATION; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION; TUNICA MEDIA; UMBILICAL VEIN ENDOTHELIAL CELL; VASA VASORUM; GENETICS; METABOLISM;

CYTOKINE RECEPTOR GP130; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INFLAMMATION MEDIATORS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-23 SUBUNIT P19; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84962496695     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.aad2357     Document Type: Article

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