-
1
-
-
0033564349
-
Angiogenesis and hematopoiesis induced by Kaposi's sarcoma-associated herpesvirus-encoded interleukin-6
-
Aoki, Y., E. S. Jaffe, Y. Chang, K. Jones, J. Teruya-Feldstein, P. S. Moore, and G. Tosato. 1999. Angiogenesis and hematopoiesis induced by Kaposi's sarcoma-associated herpesvirus-encoded interleukin-6. Blood 93:4034-4043.
-
(1999)
Blood
, vol.93
, pp. 4034-4043
-
-
Aoki, Y.1
Jaffe, E.S.2
Chang, Y.3
Jones, K.4
Teruya-Feldstein, J.5
Moore, P.S.6
Tosato, G.7
-
2
-
-
0345735665
-
Molecular mechanisms for viral mimicry of a human cytokine: Activation of gp130 by HHV-8 interleukin-6
-
Boulanger, M. J., D. C. Chow, E. Brevnova, M. Martick, G. Sandford, J. Nicholas, and K. C. Garcia. 2004. Molecular mechanisms for viral mimicry of a human cytokine: activation of gp130 by HHV-8 interleukin-6. J. Mol. Biol. 335:641-654.
-
(2004)
J. Mol. Biol
, vol.335
, pp. 641-654
-
-
Boulanger, M.J.1
Chow, D.C.2
Brevnova, E.3
Martick, M.4
Sandford, G.5
Nicholas, J.6
Garcia, K.C.7
-
3
-
-
0035129909
-
Colocalization of the viral interleukin-6 with latent nuclear antigen-1 of human herpesvirus-8 in endothelial spindle cells of Kaposi's sarcoma and lymphoid cells of multicentric Castleman's disease
-
Brousset, P., E. Cesarman, F. Meggetto, L. Lamant, and G. Delsol. 2001. Colocalization of the viral interleukin-6 with latent nuclear antigen-1 of human herpesvirus-8 in endothelial spindle cells of Kaposi's sarcoma and lymphoid cells of multicentric Castleman's disease. Hum. Pathol. 32:95-100.
-
(2001)
Hum. Pathol
, vol.32
, pp. 95-100
-
-
Brousset, P.1
Cesarman, E.2
Meggetto, F.3
Lamant, L.4
Delsol, G.5
-
4
-
-
0032521208
-
Human herpesvirus type 8 interleukin-6 homologue is functionally active on human myeloma cells
-
Burger, R., F. Neipel, B. Fleckenstein, R. Savino, G. Ciliberto, J. R. Kalden, and M. Gramatzki. 1998. Human herpesvirus type 8 interleukin-6 homologue is functionally active on human myeloma cells. Blood 91:1858-1863.
-
(1998)
Blood
, vol.91
, pp. 1858-1863
-
-
Burger, R.1
Neipel, F.2
Fleckenstein, B.3
Savino, R.4
Ciliberto, G.5
Kalden, J.R.6
Gramatzki, M.7
-
5
-
-
0032852656
-
Heterogeneity of viral IL-6 expression in HHV-8-associated diseases
-
Cannon, J. S., J. Nicholas, J. M. Orenstein, R. B. Mann, P. G. Murray, P. J. Browning, J. A. DiGiuseppe, E. Cesarman, G. S. Hayward, and R. F. Ambinder. 1999. Heterogeneity of viral IL-6 expression in HHV-8-associated diseases. J. Infect. Dis. 180:824-828.
-
(1999)
J. Infect. Dis
, vol.180
, pp. 824-828
-
-
Cannon, J.S.1
Nicholas, J.2
Orenstein, J.M.3
Mann, R.B.4
Murray, P.G.5
Browning, P.J.6
DiGiuseppe, J.A.7
Cesarman, E.8
Hayward, G.S.9
Ambinder, R.F.10
-
6
-
-
0037271977
-
Self-inactivating lentiviral vectors and a sensitive Cre-loxP reporter system
-
Chang, L. J., and A. K. Zaiss. 2003. Self-inactivating lentiviral vectors and a sensitive Cre-loxP reporter system. Methods Mol. Med. 76:367-382.
-
(2003)
Methods Mol. Med
, vol.76
, pp. 367-382
-
-
Chang, L.J.1
Zaiss, A.K.2
-
7
-
-
0037112208
-
Viral IL-6-induced cell proliferation and immune evasion of interferon activity
-
Chatterjee, M., J. Osborne, G. Bestetti, Y. Chang, and P. S. Moore. 2002. Viral IL-6-induced cell proliferation and immune evasion of interferon activity. Science 298:1432-1435.
-
(2002)
Science
, vol.298
, pp. 1432-1435
-
-
Chatterjee, M.1
Osborne, J.2
Bestetti, G.3
Chang, Y.4
Moore, P.S.5
-
8
-
-
33748938225
-
Structural requirements for gp80 independence of human herpesvirus 8 interleukin-6 (vIL-6) and evidence for gp80 stabilization of gp130 signaling complexes induced by vIL-6
-
Chen, D., and J. Nicholas. 2006. Structural requirements for gp80 independence of human herpesvirus 8 interleukin-6 (vIL-6) and evidence for gp80 stabilization of gp130 signaling complexes induced by vIL-6. J. Virol. 80:9811-9821.
-
(2006)
J. Virol
, vol.80
, pp. 9811-9821
-
-
Chen, D.1
Nicholas, J.2
-
9
-
-
0036118279
-
Patterns of gene expression and a transactivation function exhibited by the vGCR (ORF74) chemokine receptor protein of Kaposi's sarcoma-associated herpesvirus
-
Chiou, C. J., L. J. Poole, P. S. Kim, D. M. Ciufo, J. S. Cannon, C. M. ap Rhys, D. J. Alcendor, J. C. Zong, R. F. Ambinder, and G. S. Hayward. 2002. Patterns of gene expression and a transactivation function exhibited by the vGCR (ORF74) chemokine receptor protein of Kaposi's sarcoma-associated herpesvirus. J. Virol. 76:3421-3439.
-
(2002)
J. Virol
, vol.76
, pp. 3421-3439
-
-
Chiou, C.J.1
Poole, L.J.2
Kim, P.S.3
Ciufo, D.M.4
Cannon, J.S.5
ap Rhys, C.M.6
Alcendor, D.J.7
Zong, J.C.8
Ambinder, R.F.9
Hayward, G.S.10
-
10
-
-
0035896394
-
Structure of an extracellular gp130 cytokine receptor signaling complex
-
Chow, D., X. He, A. L. Snow, S. Rose-John, and K. C. Garcia. 2001. Structure of an extracellular gp130 cytokine receptor signaling complex. Science 291:2150-2155.
-
(2001)
Science
, vol.291
, pp. 2150-2155
-
-
Chow, D.1
He, X.2
Snow, A.L.3
Rose-John, S.4
Garcia, K.C.5
-
11
-
-
0345367426
-
Kaposi's sarcoma: A result of the interplay among inflammatory cytokines, angiogenic factors and viral agents
-
Ensoli, B., and M. Sturzl. 1998. Kaposi's sarcoma: a result of the interplay among inflammatory cytokines, angiogenic factors and viral agents. Cytokine Growth Factor Rev. 9:63-83.
-
(1998)
Cytokine Growth Factor Rev
, vol.9
, pp. 63-83
-
-
Ensoli, B.1
Sturzl, M.2
-
12
-
-
12144290834
-
The role of the inhibitors of interleukin-6 signal transduction SHP2 and SOCS3 for desensitization of interleukin-6 signalling
-
Fischer, P., U. Lehmann, R. M. Sobota, J. Schmitz, C. Niemand, S. Linnemann, S. Haan, I. Behrmann, A. Yoshimura, J. A. Johnston, G. Muller-Newen, P. C. Heinrich, and F. Schaper. 2004. The role of the inhibitors of interleukin-6 signal transduction SHP2 and SOCS3 for desensitization of interleukin-6 signalling. Biochem. J. 378:449-460.
-
(2004)
Biochem. J
, vol.378
, pp. 449-460
-
-
Fischer, P.1
Lehmann, U.2
Sobota, R.M.3
Schmitz, J.4
Niemand, C.5
Linnemann, S.6
Haan, S.7
Behrmann, I.8
Yoshimura, A.9
Johnston, J.A.10
Muller-Newen, G.11
Heinrich, P.C.12
Schaper, F.13
-
13
-
-
0001640974
-
Human herpes virus 8 interleukin-6 homologue triggers gp130 on neuronal and hematopoietic cells
-
Hoischen, S. H., P. Vollmer, P. Marz, S. Ozbek, K. S. Gotze, C. Peschel, T. Jostock, T. Geib, J. Mullberg, S. Mechtersheimer, M. Fischer, J. Grotzinger, P. R. Galle, and S. Rose-John. 2000. Human herpes virus 8 interleukin-6 homologue triggers gp130 on neuronal and hematopoietic cells. Eur. J. Biochem. 267:3604-3612.
-
(2000)
Eur. J. Biochem
, vol.267
, pp. 3604-3612
-
-
Hoischen, S.H.1
Vollmer, P.2
Marz, P.3
Ozbek, S.4
Gotze, K.S.5
Peschel, C.6
Jostock, T.7
Geib, T.8
Mullberg, J.9
Mechtersheimer, S.10
Fischer, M.11
Grotzinger, J.12
Galle, P.R.13
Rose-John, S.14
-
14
-
-
33750316901
-
Signal transduction by human herpesvirus 8 viral interleukin-6 (vIL-6) is modulated by the nonsignaling gp80 subunit of the IL-6 receptor complex and is distinct from signaling induced by human IL-6
-
Hu, F., and J. Nicholas. 2006. Signal transduction by human herpesvirus 8 viral interleukin-6 (vIL-6) is modulated by the nonsignaling gp80 subunit of the IL-6 receptor complex and is distinct from signaling induced by human IL-6. J. Virol. 80:10874-10878.
-
(2006)
J. Virol
, vol.80
, pp. 10874-10878
-
-
Hu, F.1
Nicholas, J.2
-
15
-
-
0032857038
-
Involvement of interleukin-10 (IL-10) and viral IL-6 in the spontaneous growth of Kaposi's sarcoma herpesvirus-associated infected primary effusion lymphoma cells
-
Jones, K. D., Y. Aoki, Y. Chang, P. S. Moore, R. Yarchoan, and G. Tosato. 1999. Involvement of interleukin-10 (IL-10) and viral IL-6 in the spontaneous growth of Kaposi's sarcoma herpesvirus-associated infected primary effusion lymphoma cells. Blood 94:2871-2879.
-
(1999)
Blood
, vol.94
, pp. 2871-2879
-
-
Jones, K.D.1
Aoki, Y.2
Chang, Y.3
Moore, P.S.4
Yarchoan, R.5
Tosato, G.6
-
16
-
-
33748653151
-
Abrogation of viral interleukin-6 (vIL-6)-induced signaling by intracellular retention and neutralization of vIL-6 with an anti-vIL-6 single-chain antibody selected by phage display
-
Kovaleva, M., I. Bussmeyer, B. Rabe, J. Grotzinger, E. Sudarman, J. Eichler, U. Conrad, S. Rose-John, and J. Scheller. 2006. Abrogation of viral interleukin-6 (vIL-6)-induced signaling by intracellular retention and neutralization of vIL-6 with an anti-vIL-6 single-chain antibody selected by phage display. J. Virol. 80:8510-8520.
-
(2006)
J. Virol
, vol.80
, pp. 8510-8520
-
-
Kovaleva, M.1
Bussmeyer, I.2
Rabe, B.3
Grotzinger, J.4
Sudarman, E.5
Eichler, J.6
Conrad, U.7
Rose-John, S.8
Scheller, J.9
-
17
-
-
0036091823
-
Identification of amino acid residues of gp130 signal transducer and gp80 alpha receptor subunit that are involved in ligand binding and signaling by human herpesvirus 8-encoded interleukin-6
-
Li, H., and J. Nicholas. 2002. Identification of amino acid residues of gp130 signal transducer and gp80 alpha receptor subunit that are involved in ligand binding and signaling by human herpesvirus 8-encoded interleukin-6. J. Virol. 76:5627-5636.
-
(2002)
J. Virol
, vol.76
, pp. 5627-5636
-
-
Li, H.1
Nicholas, J.2
-
18
-
-
0035100736
-
Detection of direct binding of human herpesvirus 8-encoded interleukin-6 (vIL-6) to both gp130 and IL-6 receptor (IL-6R) and identification of amino acid residues of vIL-6 important for IL-6R-dependent and -independent signaling
-
Li, H., H. Wang, and J. Nicholas. 2001. Detection of direct binding of human herpesvirus 8-encoded interleukin-6 (vIL-6) to both gp130 and IL-6 receptor (IL-6R) and identification of amino acid residues of vIL-6 important for IL-6R-dependent and -independent signaling. J. Virol. 75:3325-3334.
-
(2001)
J. Virol
, vol.75
, pp. 3325-3334
-
-
Li, H.1
Wang, H.2
Nicholas, J.3
-
19
-
-
10644253485
-
Kaposi's sarcoma-associated herpesvirus-encoded viral interleukin-6 is secreted and modified differently than human interleukin-6: Evidence for a unique autocrine signaling mechanism
-
Meads, M. B., and P. G. Medveczky. 2004. Kaposi's sarcoma-associated herpesvirus-encoded viral interleukin-6 is secreted and modified differently than human interleukin-6: evidence for a unique autocrine signaling mechanism. J. Biol. Chem. 279:51793-51803.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 51793-51803
-
-
Meads, M.B.1
Medveczky, P.G.2
-
20
-
-
0025288582
-
AIDS Kaposi sarcoma-derived cells produce and respond to interleukin 6
-
Miles, S. A., A. R. Rezai, J. F. Salazar-Gonzalez, M. Vander Meyden, R. H. Stevens, D. M. Logan, R. T. Mitsuyasu, T. Taga, T. Hirano, T. Kishimoto, et al. 1990. AIDS Kaposi sarcoma-derived cells produce and respond to interleukin 6. Proc. Natl. Acad. Sci. USA 87:4068-4072.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 4068-4072
-
-
Miles, S.A.1
Rezai, A.R.2
Salazar-Gonzalez, J.F.3
Vander Meyden, M.4
Stevens, R.H.5
Logan, D.M.6
Mitsuyasu, R.T.7
Taga, T.8
Hirano, T.9
Kishimoto, T.10
-
21
-
-
0030852894
-
A Kaposi's sarcoma-associated herpesvirus-encoded cytokine homolog (vIL-6) activates signaling through the shared gp130 receptor subunit
-
Molden, J., Y. Chang, Y. You, P. S. Moore, and M. A. Goldsmith. 1997. A Kaposi's sarcoma-associated herpesvirus-encoded cytokine homolog (vIL-6) activates signaling through the shared gp130 receptor subunit. J. Biol. Chem. 272:19625-19631.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 19625-19631
-
-
Molden, J.1
Chang, Y.2
You, Y.3
Moore, P.S.4
Goldsmith, M.A.5
-
22
-
-
0034080072
-
Human herpesvirus 8-encoded interleukin-6 homologue (viral IL-6) induces endogenous human IL-6 secretion
-
Mori, Y., N. Nishimoto, M. Ohno, R. Inagi, P. Dhepakson, K. Amou, K. Yoshizaki, and K. Yamanishi. 2000. Human herpesvirus 8-encoded interleukin-6 homologue (viral IL-6) induces endogenous human IL-6 secretion. J. Med. Virol. 61:332-335.
-
(2000)
J. Med. Virol
, vol.61
, pp. 332-335
-
-
Mori, Y.1
Nishimoto, N.2
Ohno, M.3
Inagi, R.4
Dhepakson, P.5
Amou, K.6
Yoshizaki, K.7
Yamanishi, K.8
-
23
-
-
16944362511
-
Kaposi's sarcoma-associated human herpesvirus-8 encodes homologues of macrophage inflammatory protein-1 and interleukin-6
-
Nicholas, J., V. R. Ruvolo, W. H. Burns, G. Sandford, X. Wan, D. Ciufo, S. B. Hendrickson, H. G. Guo, G. S. Hayward, and M. S. Reitz. 1997. Kaposi's sarcoma-associated human herpesvirus-8 encodes homologues of macrophage inflammatory protein-1 and interleukin-6. Nat. Med. 3:287-292.
-
(1997)
Nat. Med
, vol.3
, pp. 287-292
-
-
Nicholas, J.1
Ruvolo, V.R.2
Burns, W.H.3
Sandford, G.4
Wan, X.5
Ciufo, D.6
Hendrickson, S.B.7
Guo, H.G.8
Hayward, G.S.9
Reitz, M.S.10
-
24
-
-
0033901248
-
Differential viral protein expression in Kaposi's sarcoma-associated herpesvirus-infected diseases: Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease
-
Parravicini, C., B. Chandran, M. Corbellino, E. Berti, M. Paulli, P. S. Moore, and Y. Chang. 2000. Differential viral protein expression in Kaposi's sarcoma-associated herpesvirus-infected diseases: Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease. Am. J. Pathol. 156:743-749.
-
(2000)
Am. J. Pathol
, vol.156
, pp. 743-749
-
-
Parravicini, C.1
Chandran, B.2
Corbellino, M.3
Berti, E.4
Paulli, M.5
Moore, P.S.6
Chang, Y.7
-
25
-
-
0027451981
-
Intracellular retention of interleukin-6 abrogates signaling
-
Rose-John, S., H. Schooltink, H. Schmitz-Van de Leur, J. Mullberg, P. C. Heinrich, and L. Graeve. 1993. Intracellular retention of interleukin-6 abrogates signaling. J. Biol. Chem. 268:22084-22091.
-
(1993)
J. Biol. Chem
, vol.268
, pp. 22084-22091
-
-
Rose-John, S.1
Schooltink, H.2
Schmitz-Van de Leur, H.3
Mullberg, J.4
Heinrich, P.C.5
Graeve, L.6
-
26
-
-
0032899921
-
Cellular tropism and viral interleukin-6 expression distinguish human herpesvirus 8 involvement in Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease
-
Staskus, K. A., R. Sun, G. Miller, P. Racz, A. Jaslowski, C. Metroka, H. Brett-Smith, and A. T. Haase. 1999. Cellular tropism and viral interleukin-6 expression distinguish human herpesvirus 8 involvement in Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease. J. Virol. 73:4181-4187.
-
(1999)
J. Virol
, vol.73
, pp. 4181-4187
-
-
Staskus, K.A.1
Sun, R.2
Miller, G.3
Racz, P.4
Jaslowski, A.5
Metroka, C.6
Brett-Smith, H.7
Haase, A.T.8
-
27
-
-
0034705453
-
The inhibition of interleukin-6-dependent STAT activation by mitogen-activated protein kinases depends on tyrosine 759 in the cytoplasmic tail of glycoprotein 130
-
Terstegen, L., P. Gatsios, J. G. Bode, F. Schaper, P. C. Heinrich, and L. Graeve. 2000. The inhibition of interleukin-6-dependent STAT activation by mitogen-activated protein kinases depends on tyrosine 759 in the cytoplasmic tail of glycoprotein 130. J. Biol. Chem. 275:18810-18817.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 18810-18817
-
-
Terstegen, L.1
Gatsios, P.2
Bode, J.G.3
Schaper, F.4
Heinrich, P.C.5
Graeve, L.6
-
28
-
-
0032851788
-
Human herpesvirus 8 interleukin-6 (vIL-6) signals through gp130 but has structural and receptor-binding properties distinct from those of human IL-6
-
Wan, X., H. Wang, and J. Nicholas. 1999. Human herpesvirus 8 interleukin-6 (vIL-6) signals through gp130 but has structural and receptor-binding properties distinct from those of human IL-6. J. Virol. 73:8268-8278.
-
(1999)
J. Virol
, vol.73
, pp. 8268-8278
-
-
Wan, X.1
Wang, H.2
Nicholas, J.3
-
29
-
-
0024459013
-
Pathogenic significance of interleukin-6 (IL-6/BSF-2) in Castleman's disease
-
Yoshizaki, K., T. Matsuda, N. Nishimoto, T. Kuritani, L. Taeho, K. Aozasa, T. Nakahata, H. Kawai, H. Tagoh, T. Komori, et al. 1989. Pathogenic significance of interleukin-6 (IL-6/BSF-2) in Castleman's disease. Blood 74:1360-1367.
-
(1989)
Blood
, vol.74
, pp. 1360-1367
-
-
Yoshizaki, K.1
Matsuda, T.2
Nishimoto, N.3
Kuritani, T.4
Taeho, L.5
Aozasa, K.6
Nakahata, T.7
Kawai, H.8
Tagoh, H.9
Komori, T.10
-
30
-
-
41649097747
-
Blockade of viral interleukin-6 expression of Kaposi's sarcoma-associated herpesvirus
-
Zhang, Y. J., R. S. Bonaparte, D. Patel, D. A. Stein, and P. L. Iversen. 2008. Blockade of viral interleukin-6 expression of Kaposi's sarcoma-associated herpesvirus. Mol. Cancer Ther. 7:712-720.
-
(2008)
Mol. Cancer Ther
, vol.7
, pp. 712-720
-
-
Zhang, Y.J.1
Bonaparte, R.S.2
Patel, D.3
Stein, D.A.4
Iversen, P.L.5
|