-
2
-
-
0042008128
-
Survival and proliferation factors of normal and malignant plasma cells
-
Klein B, et al. (2003) Survival and proliferation factors of normal and malignant plasma cells. Int. J. Hematol. 78:106-13.
-
(2003)
Int. J. Hematol.
, vol.78
, pp. 106-113
-
-
Klein, B.1
-
4
-
-
33745779502
-
The molecular classification of multiple myeloma
-
Zhan F, et al. (2006) The molecular classification of multiple myeloma. Blood. 108:2020-28.
-
(2006)
Blood
, vol.108
, pp. 2020-2028
-
-
Zhan, F.1
-
5
-
-
0036808580
-
Validated genomic approach to study differentially expressed genes in complex tissues
-
Wurmbach E, et al. (2002) Validated genomic approach to study differentially expressed genes in complex tissues. Neurochem. Res. 27:1027-33.
-
(2002)
Neurochem. Res.
, vol.27
, pp. 1027-1033
-
-
Wurmbach, E.1
-
6
-
-
2442617195
-
The Bcl-2 family member Bfl-1/A1 is strongly repressed in normal and malignant plasma cells but is a potent anti-apoptotic factor for myeloma cells
-
Tarte K, et al. (2004) The Bcl-2 family member Bfl-1/A1 is strongly repressed in normal and malignant plasma cells but is a potent anti-apoptotic factor for myeloma cells. Br. J. Haematol. 125:373-82.
-
(2004)
Br. J. Haematol.
, vol.125
, pp. 373-382
-
-
Tarte, K.1
-
7
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. (2000) The hallmarks of cancer. Cell. 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
9
-
-
33846254038
-
Comparison of kinome profiles of Barrett's esophagus with normal squamous esophagus and normal gastric cardia
-
van Baal JW, et al. (2006) Comparison of kinome profiles of Barrett's esophagus with normal squamous esophagus and normal gastric cardia. Cancer Res. 66:11605-12.
-
(2006)
Cancer Res
, vol.66
, pp. 11605-11612
-
-
van Baal, J.W.1
-
10
-
-
34548039258
-
Profiling of the renal kinome: A novel tool to identify protein kinases involved in angiotensin II-dependent hypertensive renal damage
-
de Borst MH, et al. (2006) Profiling of the renal kinome: A novel tool to identify protein kinases involved in angiotensin II-dependent hypertensive renal damage. Am. J. Physiol. Renal. Physiol. 293:F428-37.
-
(2006)
Am. J. Physiol. Renal. Physiol.
, vol.293
-
-
de Borst, M.H.1
-
11
-
-
33745131127
-
Kinome analysis reveals nongenomic glucocorticoid receptordependent inhibition of insulin signaling
-
Lowenberg M, et al. (2006) Kinome analysis reveals nongenomic glucocorticoid receptordependent inhibition of insulin signaling. Endocrinology. 147:3555-62.
-
(2006)
Endocrinology
, vol.147
, pp. 3555-3562
-
-
Lowenberg, M.1
-
12
-
-
1642348370
-
Flow cytometric immunophenotypic analysis of 306 cases of multiple myeloma
-
Lin P, Owens R, Tricot G, Wilson CS. (2004) Flow cytometric immunophenotypic analysis of 306 cases of multiple myeloma. Am. J. Clin. Pathol. 121:482-88.
-
(2004)
Am. J. Clin. Pathol.
, vol.121
, pp. 482-488
-
-
Lin, P.1
Owens, R.2
Tricot, G.3
Wilson, C.S.4
-
13
-
-
66549106493
-
The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor
-
Sprynski AC, et al. (2009) The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. Blood. 113:4614-26.
-
(2009)
Blood
, vol.113
, pp. 4614-4626
-
-
Sprynski, A.C.1
-
14
-
-
68149110019
-
The role of the insulin-like growth factor 1 receptor axis in multiple myeloma
-
Menu E, Van VE, Van CB, Vanderkerken K. (2009) The role of the insulin-like growth factor 1 receptor axis in multiple myeloma. Arch. Physiol. Biochem. 115:49-57.
-
(2009)
Arch. Physiol. Biochem.
, vol.115
, pp. 49-57
-
-
Menu, E.1
Van, V.E.2
Van, C.B.3
Vanderkerken, K.4
-
15
-
-
61449122079
-
Induction of a chronic disease state in patients with smoldering or indolent multiple myeloma by targeting interleukin 1{beta}-induced interleukin 6 production and the myeloma proliferative component
-
Lust JA, et al. (2009) Induction of a chronic disease state in patients with smoldering or indolent multiple myeloma by targeting interleukin 1{beta}-induced interleukin 6 production and the myeloma proliferative component. Mayo Clin. Proc. 84:114-22.
-
(2009)
Mayo Clin. Proc.
, vol.84
, pp. 114-122
-
-
Lust, J.A.1
-
16
-
-
33644844811
-
Identification of two groups of smoldering multiple myeloma patients who are either high or low producers of interleukin-1
-
Xiong Y, et al. (2006) Identification of two groups of smoldering multiple myeloma patients who are either high or low producers of interleukin-1. J. Interferon. Cytokine Res. 26:83-95.
-
(2006)
J. Interferon. Cytokine Res.
, vol.26
, pp. 83-95
-
-
Xiong, Y.1
-
17
-
-
0026149834
-
Evidence that interleukin-1 and phorbol esters activate NF-kappa B by different pathways: Role of protein kinase C
-
Bomsztyk K, et al. (1991) Evidence that interleukin-1 and phorbol esters activate NF-kappa B by different pathways: role of protein kinase C. Cell. Regul. 2:329-35.
-
(1991)
Cell. Regul.
, vol.2
, pp. 329-335
-
-
Bomsztyk, K.1
-
18
-
-
77950818780
-
FAK activation is required for TNF-alpha-induced IL-6 production in myoblasts
-
Tseng WP, Su CM, Tang CH. (2010) FAK activation is required for TNF-alpha-induced IL-6 production in myoblasts. J. Cell. Physiol. 223:389-96.
-
(2010)
J. Cell. Physiol.
, vol.223
, pp. 389-396
-
-
Tseng, W.P.1
Su, C.M.2
Tang, C.H.3
-
19
-
-
0037342034
-
Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development
-
Saijo K, et al. (2003) Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development. Nat. Immunol. 4:274-79.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 274-279
-
-
Saijo, K.1
-
20
-
-
6344222902
-
The magnitude of Akt/phosphatidylinositol 3'-kinase proliferating signaling is related to CD45 expression in human myeloma cells
-
Descamps G, et al. (2004) The magnitude of Akt/phosphatidylinositol 3'-kinase proliferating signaling is related to CD45 expression in human myeloma cells. J. Immunol. 173:4953-59.
-
(2004)
J. Immunol.
, vol.173
, pp. 4953-4959
-
-
Descamps, G.1
-
21
-
-
0142025123
-
Preferential killing of PTEN-null myelomas by PI3K inhibitors through Akt pathway
-
Zhang J, Choi Y, Mavromatis B, Lichtenstein A, Li W. (2003) Preferential killing of PTEN-null myelomas by PI3K inhibitors through Akt pathway. Oncogene. 22:6289-95.
-
(2003)
Oncogene
, vol.22
, pp. 6289-6295
-
-
Zhang, J.1
Choi, Y.2
Mavromatis, B.3
Lichtenstein, A.4
Li, W.5
-
22
-
-
30144433469
-
Analysis of PTEN deletions and mutations in multiple myeloma
-
Chang H, et al. (2006) Analysis of PTEN deletions and mutations in multiple myeloma. Leuk. Res. 30:262-65.
-
(2006)
Leuk. Res.
, vol.30
, pp. 262-265
-
-
Chang, H.1
-
23
-
-
0031021491
-
Cyclic GMPdependent protein kinase and cellular signaling in the nervous system
-
Wang X, Robinson PJ. (1997) Cyclic GMPdependent protein kinase and cellular signaling in the nervous system. J. Neurochem. 68:443-56.
-
(1997)
J. Neurochem.
, vol.68
, pp. 443-456
-
-
Wang, X.1
Robinson, P.J.2
-
24
-
-
0037409783
-
Bone marrow angiogenesis and progression in multiple myeloma: Clinical significance and therapeutic approach
-
Eleutherakis-Papaiakovou V, Karali M, Kokkonouzis I, Tiliakos I, Dimopoulos MA. (2003) Bone marrow angiogenesis and progression in multiple myeloma: clinical significance and therapeutic approach. Leuk. Lymphoma. 44:937-48.
-
(2003)
Leuk. Lymphoma.
, vol.44
, pp. 937-948
-
-
Eleutherakis-Papaiakovou, V.1
Karali, M.2
Kokkonouzis, I.3
Tiliakos, I.4
Dimopoulos, M.A.5
-
25
-
-
7044234480
-
Insulin activates vascular endothelial growth factor in vascular smooth muscle cells: Influence of nitric oxide and of insulin resistance
-
Doronzo G, et al. (2004) Insulin activates vascular endothelial growth factor in vascular smooth muscle cells: influence of nitric oxide and of insulin resistance. Eur. J. Clin. Invest. 34:664-73.
-
(2004)
Eur. J. Clin. Invest.
, vol.34
, pp. 664-673
-
-
Doronzo, G.1
-
26
-
-
77649305672
-
Levels of angiogenic factors in patients with multiple myeloma correlate with treatment response
-
Pour L, et al. (2009) Levels of angiogenic factors in patients with multiple myeloma correlate with treatment response. Ann. Hematol. 89:385-9.
-
(2009)
Ann. Hematol.
, vol.89
, pp. 385-389
-
-
Pour, L.1
-
27
-
-
0035571229
-
Expression of nitric oxide synthase isoforms and nitrotyrosine immunoreactivity by B-cell non-Hodgkin's lymphomas and multiple myeloma
-
Mendes RV, Martins AR, de NG, Murad F, Soares FA. (2001) Expression of nitric oxide synthase isoforms and nitrotyrosine immunoreactivity by B-cell non-Hodgkin's lymphomas and multiple myeloma. Histopathology. 39:172-8.
-
(2001)
Histopathology
, vol.39
, pp. 172-178
-
-
Mendes, R.V.1
Martins, A.R.2
De, N.G.3
Murad, F.4
Soares, F.A.5
-
28
-
-
11244325899
-
Oxidant/antioxidant parameters and their relationship with medical treatment in multiple myeloma
-
Kuku I, et al. (2005) Oxidant/antioxidant parameters and their relationship with medical treatment in multiple myeloma. Cell. Biochem. Funct. 23:47-50.
-
(2005)
Cell. Biochem. Funct.
, vol.23
, pp. 47-50
-
-
Kuku, I.1
-
29
-
-
0037326481
-
A nitric oxide synthase inhibitor, N(G)-nitro-l-arginine-methyl-ester, exerts potent antiangiogenic effects on plasmacytoma in a newly established multiple myeloma severe combined immunodeficient mouse model
-
Uneda S, et al. (2003) A nitric oxide synthase inhibitor, N(G)-nitro-l-arginine-methyl-ester, exerts potent antiangiogenic effects on plasmacytoma in a newly established multiple myeloma severe combined immunodeficient mouse model. Br. J. Haematol. 120:396-404.
-
(2003)
Br. J. Haematol.
, vol.120
, pp. 396-404
-
-
Uneda, S.1
-
30
-
-
0033828545
-
Mechanisms involved in the proand anti-apoptotic role of NO in human leukemia
-
Kolb JP. (2000) Mechanisms involved in the proand anti-apoptotic role of NO in human leukemia. Leukemia. 14:1685-94.
-
(2000)
Leukemia
, vol.14
, pp. 1685-1694
-
-
Kolb, J.P.1
-
31
-
-
33748913900
-
Beyond single-agent bortezomib: Combination regimens in relapsed multiple myeloma
-
Richardson PG, Mitsiades C, Ghobrial I, Anderson K. (2006) Beyond single-agent bortezomib: combination regimens in relapsed multiple myeloma. Curr. Opin. Oncol. 18:598-608.
-
(2006)
Curr. Opin. Oncol.
, vol.18
, pp. 598-608
-
-
Richardson, P.G.1
Mitsiades, C.2
Ghobrial, I.3
Anderson, K.4
-
32
-
-
38749084953
-
Bortezomib in combination with conventional chemotherapeutic agents for multiple myeloma compared with bortezomib alone
-
Min CK, et al. (2007) Bortezomib in combination with conventional chemotherapeutic agents for multiple myeloma compared with bortezomib alone. Jpn. J. Clin. Oncol. 37:961-8.
-
(2007)
Jpn. J. Clin. Oncol.
, vol.37
, pp. 961-968
-
-
Min, C.K.1
-
33
-
-
66149146607
-
Bortezomib: A review of its use in patients with multiple myeloma
-
Curran MP, McKeage K. (2009) Bortezomib: a review of its use in patients with multiple myeloma. Drugs. 69:859-88.
-
(2009)
Drugs
, vol.69
, pp. 859-888
-
-
Curran, M.P.1
McKeage, K.2
-
34
-
-
41949099660
-
Alkylating agents induce activation of NFkappaB in multiple myeloma cells
-
Baumann P, Mandl-Weber S, Oduncu F, Schmidmaier R. (2008) Alkylating agents induce activation of NFkappaB in multiple myeloma cells. Leuk. Res. 32:1144-7.
-
(2008)
Leuk. Res.
, vol.32
, pp. 1144-1147
-
-
Baumann, P.1
Mandl-Weber, S.2
Oduncu, F.3
Schmidmaier, R.4
-
35
-
-
0030864876
-
Dexamethasone induces apoptosis of multiple myeloma cells in a JNK/SAP kinase independent mechanism
-
Chauhan D, et al. (1997) Dexamethasone induces apoptosis of multiple myeloma cells in a JNK/SAP kinase independent mechanism. Oncogene. 15:837-43.
-
(1997)
Oncogene
, vol.15
, pp. 837-843
-
-
Chauhan, D.1
-
36
-
-
17444440115
-
Rapamycin sensitizes multiple myeloma cells to apoptosis induced by dexamethasone
-
Stromberg T, et al. (2004) Rapamycin sensitizes multiple myeloma cells to apoptosis induced by dexamethasone. Blood. 103:3138-47.
-
(2004)
Blood
, vol.103
, pp. 3138-3147
-
-
Stromberg, T.1
-
37
-
-
33644516582
-
Mechanism by which mammalian target of rapamycin inhibitors sensitize multiple myeloma cells to dexamethasone-induced apoptosis
-
Yan H, et al. (2006) Mechanism by which mammalian target of rapamycin inhibitors sensitize multiple myeloma cells to dexamethasone-induced apoptosis. Cancer Res. 66:2305-13.
-
(2006)
Cancer Res
, vol.66
, pp. 2305-2313
-
-
Yan, H.1
-
38
-
-
58149481284
-
The novel orally bioavailable inhibitor of phosphoinositol-3-kinase and mammalian target of rapamycin, NVP-BEZ235, inhibits growth and proliferation in multiple myeloma
-
Baumann P, Mandl-Weber S, Oduncu F, Schmidmaier R. (2009) The novel orally bioavailable inhibitor of phosphoinositol-3-kinase and mammalian target of rapamycin, NVP-BEZ235, inhibits growth and proliferation in multiple myeloma. Exp. Cell Res. 315:485-97.
-
(2009)
Exp. Cell Res.
, vol.315
, pp. 485-497
-
-
Baumann, P.1
Mandl-Weber, S.2
Oduncu, F.3
Schmidmaier, R.4
-
39
-
-
72149090432
-
Evaluating temsirolimus activity in multiple tumors: A review of clinical trials
-
Suppl
-
Dancey JE, Curiel R, Purvis J. (2009) Evaluating temsirolimus activity in multiple tumors: a review of clinical trials. Semin. Oncol. 36(Suppl 3):S46-58.
-
(2009)
Semin. Oncol.
, vol.36
, Issue.3
-
-
Dancey, J.E.1
Curiel, R.2
Purvis, J.3
-
40
-
-
43749103335
-
Phase I pharmacokinetic and pharmacodynamic study of the oral, smallmolecule mitogen-activated protein kinase kinase 1/2 inhibitor AZD6244 (ARRY-142886) in patients with advanced cancers
-
Adjei AA, et al. (2008) Phase I pharmacokinetic and pharmacodynamic study of the oral, smallmolecule mitogen-activated protein kinase kinase 1/2 inhibitor AZD6244 (ARRY-142886) in patients with advanced cancers. J. Clin. Oncol. 26:2139-46.
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 2139-2146
-
-
Adjei, A.A.1
|