-
1
-
-
85052182279
-
Principles of drug absorption
-
GS Banker, CT Rhodes eds. 2nd ed. New York: Marcel Dekker
-
M Mayersohn. Principles of drug absorption. In: GS Banker, CT Rhodes, eds. Modern Pharmaceutics. 2nd ed. New York: Marcel Dekker, 1990, pp 23-90.
-
(1990)
Modern Pharmaceutics
, pp. 23-90
-
-
Mayersohn, M.1
-
2
-
-
0030580951
-
Transport approaches to the biopharmaceutical design of oral drug delivery systems: Prediction of intestinal absorption
-
LX Yu, JR Crison, E Lipka, GL Amidon. Transport approaches to the biopharmaceutical design of oral drug delivery systems: Prediction of intestinal absorption. Adv Drug Delivery Rev 19:359-376, 1996.
-
(1996)
Adv Drug Delivery Rev
, vol.19
, pp. 359-376
-
-
Yu, L.X.1
Crison, J.R.2
Lipka, E.3
Amidon, G.L.4
-
4
-
-
0002538616
-
Some aspects of cell permeability to weak electrolytes
-
MH Jacobs. Some aspects of cell permeability to weak electrolytes. Cold Spring Harbor Symp Quant Biol 8:30-39, 1940.
-
(1940)
Cold Spring Harbor Symp Quant Biol
, vol.8
, pp. 30-39
-
-
Jacobs, M.H.1
-
6
-
-
0000781608
-
Absorption of drugs from the stomach. I. The rat
-
LS Schanker, PA Shore, BB Brodie, CAM Hogben. Absorption of drugs from the stomach. I. The rat. J Pharmacol Exp Ther 120:528-539, 1957.
-
(1957)
J Pharmacol Exp Ther
, vol.120
, pp. 528-539
-
-
Schanker, L.S.1
Shore, P.A.2
Brodie, B.B.3
Hogben, C.A.M.4
-
7
-
-
0000781607
-
Absorption of drugs from the stomach. II. The human
-
CAM Hogben, LS Schanker, DJ Tocco, BB Brodie. Absorption of drugs from the stomach. II. The human. J Pharmacol Exp Ther 120:540-545, 1957.
-
(1957)
J Pharmacol Exp Ther
, vol.120
, pp. 540-545
-
-
Hogben, C.A.M.1
Schanker, L.S.2
Tocco, D.J.3
Brodie, B.B.4
-
8
-
-
0001787724
-
Absorption of drugs from the rat small intestine
-
LS Schanker, DJ Tocco, BB Brodie, CAM Hogben. Absorption of drugs from the rat small intestine. J Pharmacol Exp Ther 123:81-88, 1958.
-
(1958)
J Pharmacol Exp Ther
, vol.123
, pp. 81-88
-
-
Schanker, L.S.1
Tocco, D.J.2
Brodie, B.B.3
Hogben, C.A.M.4
-
9
-
-
0000371709
-
On the mechanism of intestinal absorption of drugs
-
CAM Hogben, DJ Tocco, BB Brodie, LS Schanker. On the mechanism of intestinal absorption of drugs. J Pharmacol Exp Ther 125:275-282, 1959.
-
(1959)
J Pharmacol Exp Ther
, vol.125
, pp. 275-282
-
-
Hogben, C.A.M.1
Tocco, D.J.2
Brodie, B.B.3
Schanker, L.S.4
-
10
-
-
0001217814
-
On the mechanism of absorption from the gastrointestinal tract
-
LS Schanker. On the mechanism of absorption from the gastrointestinal tract. J Med Pharm Chem 2:343, 1960.
-
(1960)
J Med Pharm Chem
, vol.2
, pp. 343
-
-
Schanker, L.S.1
-
13
-
-
0014785244
-
Theoretical model studies of drug absorption and transport in the gastrointestinal tract I
-
S Suzuki, WI Higuchi, NFH Ho. Theoretical model studies of drug absorption and transport in the gastrointestinal tract. I. J Pharm Sci 59:644-651, 1970.
-
(1970)
J Pharm Sci
, vol.59
, pp. 644-651
-
-
Suzuki, S.1
Higuchi, W.I.2
Ho, N.F.H.3
-
14
-
-
0014791567
-
Theoretical model studies of drug absorption and transport in the gastrointestinal tract II
-
A Suzuki, WI Higuchi, NFH Ho. Theoretical model studies of drug absorption and transport in the gastrointestinal tract. II. J Pharm Sci 59:651-659, 1970.
-
(1970)
J Pharm Sci
, vol.59
, pp. 651-659
-
-
Suzuki, A.1
Higuchi, W.I.2
Ho, N.F.H.3
-
15
-
-
0017454732
-
Shift of pH-absorption curves
-
D Winne. Shift of pH-absorption curves. J Pharmacok Biopharm 5:53-94, 1977.
-
(1977)
J Pharmacok Biopharm
, vol.5
, pp. 53-94
-
-
Winne, D.1
-
16
-
-
0029881811
-
Lipophilicity in molecular modeling
-
B Testa, P-A Carrupt, P Gaillard, F Billois, P Weber. Lipophilicity in molecular modeling. Pharm Res 13:335-343, 1996.
-
(1996)
Pharm Res
, vol.13
, pp. 335-343
-
-
Testa, B.1
Carrupt, P.-A.2
Gaillard, P.3
Billois, F.4
Weber, P.5
-
17
-
-
0001938735
-
The parameterization of lipophilicity and other structural properties in drug design
-
B. Testa ed. London: Academic Press
-
H van de Waterbeemd, B Testa. The parameterization of lipophilicity and other structural properties in drug design. In: B. Testa, ed. Advances in Drug Research, Vol. 16. London: Academic Press, 1987, pp 87-227.
-
(1987)
Advances in Drug Research
, vol.16
, pp. 87-227
-
-
van de Waterbeemd, H.1
Testa, B.2
-
18
-
-
0031024172
-
Discrimination between drug candidate using models for evaluation of intestinal absorption
-
BH Stewart, OH Chan, N Jezyk, D Fleisher. Discrimination between drug candidate using models for evaluation of intestinal absorption. Adv Drug Deliv Rev 23:27-45, 1997.
-
(1997)
Adv Drug Deliv Rev
, vol.23
, pp. 27-45
-
-
Stewart, B.H.1
Chan, O.H.2
Jezyk, N.3
Fleisher, D.4
-
19
-
-
0016722069
-
Selection of a reference partitioning system for drug design work
-
RN Smith, C Hansch, MM Ames. Selection of a reference partitioning system for drug design work. J Pharm Sci 64:599-606, 1975.
-
(1975)
J Pharm Sci
, vol.64
, pp. 599-606
-
-
Smith, R.N.1
Hansch, C.2
Ames, M.M.3
-
20
-
-
0002544211
-
Absorption, distribution and metabolism of drugs
-
JG Topless ed. New York: Academic Press
-
V Austel, E Kutter. Absorption, distribution and metabolism of drugs. In: JG Topless, ed. Quantitative Structure-Activity Relationships of Drugs. New York: Academic Press, 1980, pp 437-496.
-
(1980)
Quantitative Structure-Activity Relationships of Drugs
, pp. 437-496
-
-
Austel, V.1
Kutter, E.2
-
21
-
-
8644243613
-
Partition coefficients and their uses
-
A Leo, C Hansch, D Elkins. Partition coefficients and their uses. Chem Rev 71: 525-616, 1977.
-
(1977)
Chem Rev
, vol.71
, pp. 525-616
-
-
Leo, A.1
Hansch, C.2
Elkins, D.3
-
22
-
-
0001255549
-
A physical chemical basis of the design of orally active prodrugs
-
SH Yalkowsky, W Morozowich. A physical chemical basis of the design of orally active prodrugs. Drug Des 9:122-185, 1980.
-
(1980)
Drug Des
, vol.9
, pp. 122-185
-
-
Yalkowsky, S.H.1
Morozowich, W.2
-
23
-
-
0018850819
-
Physical model studies on the simultaneous fluid flow and absorption of steroids in the rat intestines
-
I Komiya, JY Park, A Kamani, NFH Ho, WI Higuchi. Physical model studies on the simultaneous fluid flow and absorption of steroids in the rat intestines. Int J Pharm 4:249-262, 1980.
-
(1980)
Int J Pharm
, vol.4
, pp. 249-262
-
-
Komiya, I.1
Park, J.Y.2
Kamani, A.3
Ho, N.F.H.4
Higuchi, W.I.5
-
24
-
-
0001935155
-
Physical model approach to the design of drugs with improved intestinal absorption
-
EB Roche ed. Washington DC: American Pharmaceutical Association, Acad Pharm Sci
-
NFH Ho, JY Park, W Morozowich, WI Higuchi. Physical model approach to the design of drugs with improved intestinal absorption. In: EB Roche, ed. Design of Biopharmaceutical Properties Through Prodrugs and Analogs. Washington DC: American Pharmaceutical Association, Acad Pharm Sci, 1977, pp 136-227.
-
(1977)
Design of Biopharmaceutical Properties Through Prodrugs and Analogs
, pp. 136-227
-
-
Ho, N.F.H.1
Park, J.Y.2
Morozowich, W.3
Higuchi, W.I.4
-
25
-
-
0024267858
-
Characterization of an in vitro blood-brain barrier: Effects of molecular size and lipophilicity on cerebrovascular endothelial transport rates of drugs
-
JBM Van Bree, AG De Boer, M Danhof, L Gisel, DD Breimer. Characterization of an in vitro blood-brain barrier: Effects of molecular size and lipophilicity on cerebrovascular endothelial transport rates of drugs. J Pharmacol Exp Ther 247: 1233-1239, 1988.
-
(1988)
J Pharmacol Exp Ther
, vol.247
, pp. 1233-1239
-
-
Van Bree, J.B.M.1
De Boer, A.G.2
Danhof, M.3
Gisel, L.4
Breimer, D.D.5
-
26
-
-
0029872476
-
Permeability of 5-fluorouracil and prodrugs in Caco-2 cell monolayers
-
A Buur, L Trier, C Magnusson, P Artursson. Permeability of 5-fluorouracil and prodrugs in Caco-2 cell monolayers. Int J Pharm 129:223-231, 1996.
-
(1996)
Int J Pharm
, vol.129
, pp. 223-231
-
-
Buur, A.1
Trier, L.2
Magnusson, C.3
Artursson, P.4
-
27
-
-
0030458462
-
How structure features influence the biomembrane permeability of peptides
-
PS Burton, RA Conradi, NFH Ho, AR Hilgers, RT Borchard. How structure features influence the biomembrane permeability of peptides. J Pharm Sci 85:1336-1340, 1996.
-
(1996)
J Pharm Sci
, vol.85
, pp. 1336-1340
-
-
Burton, P.S.1
Conradi, R.A.2
Ho, N.F.H.3
Hilgers, A.R.4
Borchard, R.T.5
-
28
-
-
0022070123
-
Absorption potential: Estimating the fraction absorbed for orally administered compounds
-
JB Dressman, GL Amidon, D Fleisher. Absorption potential: Estimating the fraction absorbed for orally administered compounds. J Pharm Sci 74:588-589, 1985.
-
(1985)
J Pharm Sci
, vol.74
, pp. 588-589
-
-
Dressman, J.B.1
Amidon, G.L.2
Fleisher, D.3
-
29
-
-
0024578889
-
Toward a quantitative approach for the prediction of the fraction of dose absorbed using the absorption potential concept
-
P Macheras, MY Symillides. Toward a quantitative approach for the prediction of the fraction of dose absorbed using the absorption potential concept. Biopharm Drug Dispos 10:43-53, 1989.
-
(1989)
Biopharm Drug Dispos
, vol.10
, pp. 43-53
-
-
Macheras, P.1
Symillides, M.Y.2
-
30
-
-
0023715382
-
Estimating human oral fraction dose absorbed: A correlation using rat intestinal membrane permeability for passive and carriermediated compounds
-
GL Amidon, PJ Sinko, D Fleisher. Estimating human oral fraction dose absorbed: A correlation using rat intestinal membrane permeability for passive and carriermediated compounds. Pharm Res 5:651-654, 1988.
-
(1988)
Pharm Res
, vol.5
, pp. 651-654
-
-
Amidon, G.L.1
Sinko, P.J.2
Fleisher, D.3
-
31
-
-
0025821306
-
Predicting fraction dose absorbed in humans using a macroscopic mass balance approach
-
PJ Sinko, GD Leesman, GL Amidon. Predicting fraction dose absorbed in humans using a macroscopic mass balance approach. Pharm Res 8:979-988, 1991.
-
(1991)
Pharm Res
, vol.8
, pp. 979-988
-
-
Sinko, P.J.1
Leesman, G.D.2
Amidon, G.L.3
-
32
-
-
0027530698
-
Mass balance approaches for estimating the intestinal absorption and metabolism of peptides and analogues: Theoretical development and applications
-
PJ Sinko, GD Leesman, GL Amidon. Mass balance approaches for estimating the intestinal absorption and metabolism of peptides and analogues: Theoretical development and applications. Pharm Res 10:271-275, 1993.
-
(1993)
Pharm Res
, vol.10
, pp. 271-275
-
-
Sinko, P.J.1
Leesman, G.D.2
Amidon, G.L.3
-
33
-
-
0028948839
-
A theoretical basis for a biopharmaceutic drug classification: The correlation of in vitro drug product dissolution and in vivo bioavailability
-
GL Amidon, H Lennernas, VP Shah, JR Crison. A theoretical basis for a biopharmaceutic drug classification: The correlation of in vitro drug product dissolution and in vivo bioavailability. Pharm Res 12:413-420, 1995.
-
(1995)
Pharm Res
, vol.12
, pp. 413-420
-
-
Amidon, G.L.1
Lennernas, H.2
Shah, V.P.3
Crison, J.R.4
-
34
-
-
0011938509
-
Predicting oral drug absorption in humans: A macroscopic mass balance approach for passive and carrier-mediated compounds
-
DZ D’Argenio, ed. New York: Plenum Press
-
DM Oh, PJ Sinko, GL Amidon. Predicting oral drug absorption in humans: A macroscopic mass balance approach for passive and carrier-mediated compounds. In:DZ D’Argenio, ed. Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis. New York: Plenum Press, 1990, pp 3-11.
-
(1990)
Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis
, pp. 3-11
-
-
Oh, D.M.1
Sinko, P.J.2
Amidon, G.L.3
-
35
-
-
0023807777
-
Characterization of the oral absorption of ß-lactam antibiotics. I. Cephalosporins: Determination of intrinsic membrane absorption parameters in the rat intestine in situ
-
PJ Sinko, GL Amidon. Characterization of the oral absorption of ß-lactam antibiotics. I. Cephalosporins: Determination of intrinsic membrane absorption parameters in the rat intestine in situ. Pharm Res 5:645-650, 1988.
-
(1988)
Pharm Res
, vol.5
, pp. 645-650
-
-
Sinko, P.J.1
Amidon, G.L.2
-
36
-
-
0024951375
-
Characterization of the oral absorption of ß-lactam antibiotics. II. Competitive absorption and peptide carrier specificity
-
PJ Sinko, GL Amidon. Characterization of the oral absorption of ß-lactam antibiotics. II. Competitive absorption and peptide carrier specificity. J Pharm Sci 78:723-727, 1989.
-
(1989)
J Pharm Sci
, vol.78
, pp. 723-727
-
-
Sinko, P.J.1
Amidon, G.L.2
-
37
-
-
0027436878
-
Characterization of the oral absorption of ß-lactam: Effect of the α-amino side chain group
-
DM Oh, PJ Sinko, GL Amidon. Characterization of the oral absorption of ß-lactam: Effect of the α-amino side chain group. J Pharm Sci 82:897-900, 1993.
-
(1993)
J Pharm Sci
, vol.82
, pp. 897-900
-
-
Oh, D.M.1
Sinko, P.J.2
Amidon, G.L.3
-
38
-
-
0030588714
-
Caco-2 monolayers in experimental and theoretical predictions of drug transport
-
P Artursson, K Palm, K Luthman. Caco-2 monolayers in experimental and theoretical predictions of drug transport. Adv Drug Deliv Rev 22:67-84, 1996.
-
(1996)
Adv Drug Deliv Rev
, vol.22
, pp. 67-84
-
-
Artursson, P.1
Palm, K.2
Luthman, K.3
-
39
-
-
0025804183
-
Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells
-
P Artursson, J Karlsson. Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells. Biochem Biophys Res Commun 175:880-885, 1991.
-
(1991)
Biochem Biophys Res Commun
, vol.175
, pp. 880-885
-
-
Artursson, P.1
Karlsson, J.2
-
40
-
-
0029020035
-
Comparison of intestinal permeabilities determined in multiple in vitro and in situ model: Relationship to absorption in humans
-
BH Stewart, OH Chan, RH Lu, EL Reyner, HL Schmid, HW Hamilton, BA Steinbaugh, MD Taylor. Comparison of intestinal permeabilities determined in multiple in vitro and in situ model: Relationship to absorption in humans. Pharm Res 12:693-699, 1995.
-
(1995)
Pharm Res
, vol.12
, pp. 693-699
-
-
Stewart, B.H.1
Chan, O.H.2
Lu, R.H.3
Reyner, E.L.4
Schmid, H.L.5
Hamilton, H.W.6
Steinbaugh, B.A.7
Taylor, M.D.8
-
41
-
-
0025732815
-
A model of human small intestinal absorptive cells 1. Transport barrier
-
JN Cogburn, MG Donovan, CS Schasteen. A model of human small intestinal absorptive cells. 1. Transport barrier. Pharm Res 9:210-216, 1991.
-
(1991)
Pharm Res
, vol.9
, pp. 210-216
-
-
Cogburn, J.N.1
Donovan, M.G.2
Schasteen, C.S.3
-
42
-
-
0027497560
-
Comparison of the permeability characteristics of a human colonic epithelial (Caco-2) cell line to colon of rabbit, monkey, and dog intestine and human drug absorption
-
W Rubas, N Jezyk, GM Grass. Comparison of the permeability characteristics of a human colonic epithelial (Caco-2) cell line to colon of rabbit, monkey, and dog intestine and human drug absorption. Pharm Res 10:113-118, 1993.
-
(1993)
Pharm Res
, vol.10
, pp. 113-118
-
-
Rubas, W.1
Jezyk, N.2
Grass, G.M.3
-
43
-
-
0027473738
-
Estimating the fraction dose absorbed from suspensions of poorly soluble compounds in humans: A mathematical model
-
DM Oh, RL Curl, GL Amidon. Estimating the fraction dose absorbed from suspensions of poorly soluble compounds in humans: A mathematical model. Pharm Res 10:264-270, 1993.
-
(1993)
Pharm Res
, vol.10
, pp. 264-270
-
-
Oh, D.M.1
Curl, R.L.2
Amidon, G.L.3
-
47
-
-
85030200732
-
Expected variation in bioavailability for water insoluble drugs
-
HH Blume, KK Midha eds. Stuttgart:Medpharm Scientific Publishers
-
JR Crison, GL Amidon. Expected variation in bioavailability for water insoluble drugs. In: HH Blume, KK Midha, eds. Bio-International 2, Bioavailability, Bioequi valence and Pharmacokinetic Studies. Stuttgart:Medpharm Scientific Publishers, 1995, pp 301-309.
-
(1995)
Bio-International 2, Bioavailability, Bioequi valence and Pharmacokinetic Studies
, pp. 301-309
-
-
Crison, J.R.1
Amidon, G.L.2
-
48
-
-
4243558762
-
The effect of particle size distribution on drug dissolution: A mathematical model for predicting dissolution and absorption of suspensions in the small intestine
-
JR Crison, GL Amidon. The effect of particle size distribution on drug dissolution: A mathematical model for predicting dissolution and absorption of suspensions in the small intestine. Pharm Res 10:S170, 1992.
-
(1992)
Pharm Res
, vol.10
, pp. S170
-
-
Crison, J.R.1
Amidon, G.L.2
-
49
-
-
0011975740
-
Theoretical model studies of intestinal drug absorption. V. Nonsteady-state fluid flow and absorption
-
PF Ni, NFH Ho, JF Fox, H Leuenberger, WI Higuchi. Theoretical model studies of intestinal drug absorption. V. Nonsteady-state fluid flow and absorption. Int J Pharm 5:33-47, 1980.
-
(1980)
Int J Pharm
, vol.5
, pp. 33-47
-
-
Ni, P.F.1
Ho, N.F.H.2
Fox, J.F.3
Leuenberger, H.4
Higuchi, W.I.5
-
50
-
-
0002698633
-
Advanced quantitative and mechanistic approaches in interfacing gastrointestinal drug absorption studies in animals and humans
-
W Crouthanel, AC Sarapu eds. Washington DC: American Pharmaceutical Association
-
NFH Ho, JY Park, PF Ni, WI Higuchi. Advanced quantitative and mechanistic approaches in interfacing gastrointestinal drug absorption studies in animals and humans. In: W Crouthanel, AC Sarapu, eds. Animal Models for Oral Drug Delivery in Man: In Situ and In Vivo Approaches. Washington DC: American Pharmaceutical Association, 1983, pp 27-106.
-
(1983)
Animal Models for Oral Drug Delivery in Man: In Situ and In Vivo Approaches
, pp. 27-106
-
-
Ho, N.F.H.1
Park, J.Y.2
Ni, P.F.3
Higuchi, W.I.4
-
51
-
-
4243642750
-
Nonsteady state model of absorption of suspensions in the GI tract: Coupling multi-phase intestinal flow with blood level kinetics
-
R Zipp, NFH Ho. Nonsteady state model of absorption of suspensions in the GI tract: Coupling multi-phase intestinal flow with blood level kinetics. Pharm Res 10: S210, 1993.
-
(1993)
Pharm Res
, vol.10
, pp. S210
-
-
Zipp, R.1
Ho, N.F.H.2
-
52
-
-
0029031147
-
Description and simulation of a tubular, plug-flow model to predict the effect of bile sequestrants on human bile salt excretion
-
RJ Leipold. Description and simulation of a tubular, plug-flow model to predict the effect of bile sequestrants on human bile salt excretion. J Pharm Sci 84:670-672, 1995.
-
(1995)
J Pharm Sci
, vol.84
, pp. 670-672
-
-
Leipold, R.J.1
-
53
-
-
0019430956
-
Predicted absorption rates with simultaneous bulk fluid flow in the intestinal tract
-
GE Amidon, NFH Ho, AB Frech, WI Higuchi. Predicted absorption rates with simultaneous bulk fluid flow in the intestinal tract. J Theor Biol 89:195-210, 1981.
-
(1981)
J Theor Biol
, vol.89
, pp. 195-210
-
-
Amidon, G.E.1
Ho, N.F.H.2
Frech, A.B.3
Higuchi, W.I.4
-
54
-
-
0020523527
-
Quantitative, mechanistic and physiologically realistic approach to the biopharmaceutical design of oral drug delivery systems
-
NFH Ho, HP Merkle, WI Higuchi. Quantitative, mechanistic and physiologically realistic approach to the biopharmaceutical design of oral drug delivery systems. Drug Deliv Ind Pharm 9:1111-1184, 1983.
-
(1983)
Drug Deliv Ind Pharm
, vol.9
, pp. 1111-1184
-
-
Ho, N.F.H.1
Merkle, H.P.2
Higuchi, W.I.3
-
55
-
-
0019830962
-
Quantitative, mechanistic and physiologically realistic approach to the biopharmaceutical design of oral drug delivery systems
-
BC Goodacre, RJ Murry. Quantitative, mechanistic and physiologically realistic approach to the biopharmaceutical design of oral drug delivery systems. J Clin Hosp Pharm 6:117-133, 1981.
-
(1981)
J Clin Hosp Pharm
, vol.6
, pp. 117-133
-
-
Goodacre, B.C.1
Murry, R.J.2
-
56
-
-
0021228359
-
Physicochemical model for dose-dependent drug absorption
-
JB Dressman, D Fleisher, GL Amidon. Physicochemical model for dose-dependent drug absorption. J Pharm Sci 73:1274-1279, 1984.
-
(1984)
J Pharm Sci
, vol.73
, pp. 1274-1279
-
-
Dressman, J.B.1
Fleisher, D.2
Amidon, G.L.3
-
57
-
-
0022618014
-
Mixing-tank model for predicting dissolution rate control of oral absorption
-
JB Dressman, D Fleisher. Mixing-tank model for predicting dissolution rate control of oral absorption. J Pharm Sci 75:109-116, 1986.
-
(1986)
J Pharm Sci
, vol.75
, pp. 109-116
-
-
Dressman, J.B.1
Fleisher, D.2
-
58
-
-
0024596954
-
The effect of particle size distribution on the dissolution rate and oral absorption
-
RJ Hintz, KC Johnson. The effect of particle size distribution on the dissolution rate and oral absorption. Int J Pharm 51:9-17, 1989.
-
(1989)
Int J Pharm
, vol.51
, pp. 9-17
-
-
Hintz, R.J.1
Johnson, K.C.2
-
59
-
-
0027275798
-
Dissolution modeling: Factors affecting the dissolution rates of polydisperse powders
-
ATK Lu, ME Frisella, KC Johnson. Dissolution modeling: Factors affecting the dissolution rates of polydisperse powders. Pharm Res 10:1308-1314, 1993.
-
(1993)
Pharm Res
, vol.10
, pp. 1308-1314
-
-
Lu, A.T.K.1
Frisella, M.E.2
Johnson, K.C.3
-
60
-
-
0030444550
-
Guidance in the setting of drug particle size specifications to minimize variability in absorption
-
KC Johnson, AC Swindell. Guidance in the setting of drug particle size specifications to minimize variability in absorption. Pharm Res 13:1795-1798, 1996.
-
(1996)
Pharm Res
, vol.13
, pp. 1795-1798
-
-
Johnson, K.C.1
Swindell, A.C.2
-
61
-
-
0023425558
-
The influence of variable gastric emptying and intestinal transit rates on the plasma level curve of cimetidine: An explanation for the double peak phenomenon
-
RL Oberle, GL Amidon. The influence of variable gastric emptying and intestinal transit rates on the plasma level curve of cimetidine: An explanation for the double peak phenomenon. J Pharmacok Biopharm 15:529-544, 1987.
-
(1987)
J Pharmacok Biopharm
, vol.15
, pp. 529-544
-
-
Oberle, R.L.1
Amidon, G.L.2
-
62
-
-
0002709183
-
Simulation of oral drug absorption: Gastric emptying and gastrointestinal motility
-
PG Welling, FLS Tse eds. 2nd ed. New York: Marcel Dekker
-
GD Leesman, PJ Sinko, GL Amidon. Simulation of oral drug absorption: Gastric emptying and gastrointestinal motility. In: PG Welling, FLS Tse, eds. Pharmacokinetics. 2nd ed. New York: Marcel Dekker, 1989, pp 267-284.
-
(1989)
Pharmacokinetics
, pp. 267-284
-
-
Leesman, G.D.1
Sinko, P.J.2
Amidon, G.L.3
-
63
-
-
0027253685
-
Description and simulation of a multiple mixing tank model to predict the effect of bile sequestrants on bile salt excretion
-
P Luner, GL Amidon. Description and simulation of a multiple mixing tank model to predict the effect of bile sequestrants on bile salt excretion. J Pharm Sci 82:311-318, 1993.
-
(1993)
J Pharm Sci
, vol.82
, pp. 311-318
-
-
Luner, P.1
Amidon, G.L.2
-
64
-
-
0029848457
-
Compartmental transit and dispersion model analysis of small intestinal transit flow in humans
-
LX Yu, JR Crison, GL Amidon. Compartmental transit and dispersion model analysis of small intestinal transit flow in humans. Int J Pharm 140:111-118, 1996.
-
(1996)
Int J Pharm
, vol.140
, pp. 111-118
-
-
Yu, L.X.1
Crison, J.R.2
Amidon, G.L.3
-
65
-
-
0032531309
-
Characterization of small intestinal transit time distribution in humans
-
LX Yu, GL Amidon. Characterization of small intestinal transit time distribution in humans. Int J Pharm 171:157-163, 1998.
-
(1998)
Int J Pharm
, vol.171
, pp. 157-163
-
-
Yu, L.X.1
Amidon, G.L.2
-
66
-
-
4243572731
-
A strategic approach for predicting oral drug absorption in humans
-
LX Yu, JR Crison, GL Amidon. A strategic approach for predicting oral drug absorption in humans. Pharm Res 12:S8, 1995.
-
(1995)
Pharm Res
, vol.12
, pp. S8
-
-
Yu, L.X.1
Crison, J.R.2
Amidon, G.L.3
-
67
-
-
0031982148
-
Saturable small intestinal drug absorption in humans: Modeling and explanation of the cefatrizine data
-
LX Yu, GL Amidon. Saturable small intestinal drug absorption in humans: Modeling and explanation of the cefatrizine data. Eur J Pharm Biopharm 45:199-203, 1998.
-
(1998)
Eur J Pharm Biopharm
, vol.45
, pp. 199-203
-
-
Yu, L.X.1
Amidon, G.L.2
-
68
-
-
85056041108
-
Optimization of dosage form release parameters based on pharmacokinetic and gastrointestinal transit time considerations
-
SY Choe, E Lipka, LX Yu, JR Crison, GL Amidon. Optimization of dosage form release parameters based on pharmacokinetic and gastrointestinal transit time considerations. Pharm Res 13:S292, 1996.
-
(1996)
Pharm Res
, vol.13
, pp. S292
-
-
Choe, S.Y.1
Lipka, E.2
Yu, L.X.3
Crison, J.R.4
Amidon, G.L.5
-
69
-
-
0029082096
-
Evaluation of the intestinal permeability of ß-blocker drugs and their potential for oral controlled release
-
E Lipka, LX Yu, D Liu, JR Crison, GL Amidon. Evaluation of the intestinal permeability of ß-blocker drugs and their potential for oral controlled release. Proc Int Symp Controlled Release Bioact Mater 22:366-367, 1995.
-
(1995)
Proc Int Symp Controlled Release Bioact Mater
, vol.22
, pp. 366-367
-
-
Lipka, E.1
Yu, L.X.2
Liu, D.3
Crison, J.R.4
Amidon, G.L.5
-
70
-
-
0022538998
-
Transit of pharmaceutical dosage forms through the small intestine
-
SS Davis, JG Hardy, JW Fara. Transit of pharmaceutical dosage forms through the small intestine. Gut 27:886-892, 1986.
-
(1986)
Gut
, vol.27
, pp. 886-892
-
-
Davis, S.S.1
Hardy, J.G.2
Fara, J.W.3
-
71
-
-
0001434647
-
Motility of the small intestine
-
LR Johnson ed. New York: Raven Press
-
NW Weisbrodt. Motility of the small intestine. In: LR Johnson, ed. Physiology of the Gastrointestinal Tract. New York: Raven Press, 1989, pp 631-664.
-
(1989)
Physiology of the Gastrointestinal Tract
, pp. 631-664
-
-
Weisbrodt, N.W.1
-
72
-
-
0020040813
-
Relationship of motility to flow of contents in the human small intestine
-
P Kerlin, A Zinsmeister, S Phillips. Relationship of motility to flow of contents in the human small intestine. Gastroenterology 82:701-706, 1982.
-
(1982)
Gastroenterology
, vol.82
, pp. 701-706
-
-
Kerlin, P.1
Zinsmeister, A.2
Phillips, S.3
-
73
-
-
0021998682
-
Clinical pharmacokinetics of the angiotension converting enzyme inhibitors
-
SH Kubo, RJ Cody. Clinical pharmacokinetics of the angiotension converting enzyme inhibitors. Clin Pharmacokinet 10:377-391, 1985.
-
(1985)
Clin Pharmacokinet
, vol.10
, pp. 377-391
-
-
Kubo, S.H.1
Cody, R.J.2
-
74
-
-
85056034512
-
Furosemide: A pharmacokinetics/pharmacodynamics review
-
LLB Ponto, RD Schoenwald. Furosemide: A pharmacokinetics/pharmacodynamics review. Clin Pharmacok 18:381-408, 1993.
-
(1993)
Clin Pharmacok
, vol.18
, pp. 381-408
-
-
Ponto, L.L.B.1
Schoenwald, R.D.2
-
75
-
-
0021317295
-
Pharmacokinetics of terbutaline after oral administration
-
DS Davies. Pharmacokinetics of terbutaline after oral administration. Eur J Resp Dis Suppl 65:111-117, 1984.
-
(1984)
Eur J Resp Dis Suppl
, vol.65
, pp. 111-117
-
-
Davies, D.S.1
-
76
-
-
0018407052
-
Kinetics and absolute bioavailability of atenolol
-
WD Mason, N Winer, G Kochak, I Cohen, R Bell. Kinetics and absolute bioavailability of atenolol. Clin Pharmacol Ther 25:408-415, 1979.
-
(1979)
Clin Pharmacol Ther
, vol.25
, pp. 408-415
-
-
Mason, W.D.1
Winer, N.2
Kochak, G.3
Cohen, I.4
Bell, R.5
-
77
-
-
0002769936
-
Design and optimization of dosage regiments; pharmacokinetic data
-
JG Hardman, LE Limbird, AG Gilman, eds. 9th ed. New York: McGraw-Hill
-
LZ Benet, S Øie, JB Schwartz. Design and optimization of dosage regiments; pharmacokinetic data. In: JG Hardman, LE Limbird, AG Gilman, eds. The Pharmacological Basis of Therapeutics. 9th ed. New York: McGraw-Hill; 1996, pp 1707-1793.
-
(1996)
The Pharmacological Basis of Therapeutics
, pp. 1707-1793
-
-
Benet, L.Z.1
Øie, S.2
Schwartz, J.B.3
-
79
-
-
0001174676
-
The pharmacodynamics and metabolism of propranolol in man
-
JW Paterson, ME Conolly, CT Dollery, A Hayes, RG Cooper. The pharmacodynamics and metabolism of propranolol in man. Pharmacol Clin 2:127-133, 1970.
-
(1970)
Pharmacol Clin
, vol.2
, pp. 127-133
-
-
Paterson, J.W.1
Conolly, M.E.2
Dollery, C.T.3
Hayes, A.4
Cooper, R.G.5
-
80
-
-
0026694388
-
Pharmacokinetics of fluvastatin after single and multiple doses in normal volunteers
-
FLS Tse, JM Jaffe, AJ Troendle. Pharmacokinetics of fluvastatin after single and multiple doses in normal volunteers. J Clin Pharmacol 32:630-638, 1992.
-
(1992)
J Clin Pharmacol
, vol.32
, pp. 630-638
-
-
Tse, F.L.S.1
Jaffe, J.M.2
Troendle, A.J.3
-
81
-
-
0020075005
-
Pharmacokinetics and metabolism of antipyrine after intravenous and oral administration
-
E Eichelbaum, HR Ochs, G Roberts, A Somogyi. Pharmacokinetics and metabolism of antipyrine after intravenous and oral administration. Arzneim-Forsch 32:575-578, 1982.
-
(1982)
Arzneim-Forsch
, vol.32
, pp. 575-578
-
-
Eichelbaum, E.1
Ochs, H.R.2
Roberts, G.3
Somogyi, A.4
-
82
-
-
0021045463
-
Human intravenous pharmacokinetics and absolute oral bioavailability of cefatrizine
-
MPfeffer, RC Gaver, J Ximenez. Human intravenous pharmacokinetics and absolute oral bioavailability of cefatrizine. Antimicrob Agents Chemother 24:915-920, 1983.
-
(1983)
Antimicrob Agents Chemother
, vol.24
, pp. 915-920
-
-
Pfeffer, M.1
Gaver, R.C.2
Ximenez, J.3
-
83
-
-
0023265275
-
Simplified assessment of segmental colonic transit
-
AM Metcalf, SF Phillips, AR Zinsmeister, RL MacCarty, RW Beart, BG Wolff. Simplified assessment of segmental colonic transit. Gastroenterology 92:40-47, 1987.
-
(1987)
Gastroenterology
, vol.92
, pp. 40-47
-
-
Metcalf, A.M.1
Phillips, S.F.2
Zinsmeister, A.R.3
MacCarty, R.L.4
Beart, R.W.5
Wolff, B.G.6
-
84
-
-
0018910140
-
Disposition of 14C-cefatrazine in man
-
RC Gaver, G Deeb. Disposition of 14C-cefatrazine in man. Drug Dis Metab Dispos 8:157-162, 1980.
-
(1980)
Drug Dis Metab Dispos
, vol.8
, pp. 157-162
-
-
Gaver, R.C.1
Deeb, G.2
-
85
-
-
0026795241
-
Regional jejunal perfusion, a new in vivo approach to study oral drug absorption in man
-
H Lennernas, O Ahrenstedt, R Hallgren, L Knutson, M Ryde, LK Paalzow. Regional jejunal perfusion, a new in vivo approach to study oral drug absorption in man. Pharm Res 9:1243-1251, 1992.
-
(1992)
Pharm Res
, vol.9
, pp. 1243-1251
-
-
Lennernas, H.1
Ahrenstedt, O.2
Hallgren, R.3
Knutson, L.4
Ryde, M.5
Paalzow, L.K.6
-
86
-
-
0030797273
-
Human jejunal effective permeability and its correlation with preclinical drug absorption models
-
H Lennernas. Human jejunal effective permeability and its correlation with preclinical drug absorption models. J Pharm Pharmacol 49:627-638, 1997.
-
(1997)
J Pharm Pharmacol
, vol.49
, pp. 627-638
-
-
Lennernas, H.1
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