High glucose stimulates tumorigenesis in hepatocellular carcinoma cells through ager-dependent O-glcnacylation of C-jun

Diabetes

Volumn 65, Issue 3, 2016, Pages 619-632

  Qiao, Yongxia ^a   Zhang, Xiao ^b   Zhang, Yue ^b   Wang, Yulan ^b   Xu, Yanfeng ^c   Liu, Xiangfan ^a   Sun, Fenyong ^b   Wang, Jiayi ^b,d  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b TENTH PEOPLE S HOSPITAL OF TONGJI UNIVERSITY   (China)

^c SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^d TONGJI UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; CASPASE 3; CASPASE 7; GLUCOSE; GLUTAMIC ACID; GLUTAMINE; HEXOSAMINE; INSULIN; ISOLEUCINE; LACTIC ACID; MESSENGER RNA; N ACETYLGLUCOSAMINE; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PHENYLALANINE; PROTEIN C JUN; THREONINE; TYROSINE; GLUCOSE BLOOD LEVEL; N ACETYLGLUCOSAMINYLTRANSFERASE; O-GLCNAC TRANSFERASE;

ACYLATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOREGULATION; BIOSYNTHESIS; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; FEEDBACK SYSTEM; GLUCOSE BLOOD LEVEL; GLUCOSE INTAKE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INSULIN TREATMENT; LIVER CARCINOGENESIS; LIVER CELL; LIVER CELL CARCINOMA; MALE; MASS FRAGMENTOGRAPHY; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; PROTEIN TARGETING; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; TUMOR VOLUME; UBIQUITINATION; ANIMAL; BAGG ALBINO MOUSE; CARCINOGENESIS; EXPERIMENTAL DIABETES MELLITUS; FLUORESCENT ANTIBODY TECHNIQUE; HEPG2 CELL LINE; IMMUNOBLOTTING; IMMUNOPRECIPITATION; LIVER TUMOR; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR CELL LINE; WESTERN BLOTTING;

ACYLATION; ADVANCED GLYCOSYLATION END PRODUCT-SPECIFIC RECEPTOR; ANIMALS; BLOOD GLUCOSE; BLOTTING, WESTERN; CARCINOGENESIS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL PROLIFERATION; DIABETES MELLITUS, EXPERIMENTAL; FLUORESCENT ANTIBODY TECHNIQUE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HEP G2 CELLS; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; LIVER NEOPLASMS; MICE; MICE, INBRED BALB C; N-ACETYLGLUCOSAMINYLTRANSFERASES; PROTO-ONCOGENE PROTEINS C-JUN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 84962436313     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db15-1057     Document Type: Article

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