-
3
-
-
51349156218
-
Insulin sensitivity: Modulation by nutrients and inflammation
-
Schenk S, Saberi M, Olefsky JM. Insulin sensitivity: modulation by nutrients and inflammation. J Clin Invest 2008; 118: 2992-3002
-
(2008)
J Clin Invest
, vol.118
, pp. 2992-3002
-
-
Schenk, S.1
Saberi, M.2
Olefsky, J.M.3
-
4
-
-
0021994683
-
Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus
-
DeFronzo RA, Gunnarsson R, Björkman O, Olsson M, Wahren J. Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus. J Clin Invest 1985; 76: 149-155
-
(1985)
J Clin Invest
, vol.76
, pp. 149-155
-
-
DeFronzo, R.A.1
Gunnarsson, R.2
Björkman, O.3
Olsson, M.4
Wahren, J.5
-
5
-
-
84874624368
-
Muscle lipogenesis balances insulin sensitivity and strength through calcium signaling
-
Funai K, Song H, Yin L, et al. Muscle lipogenesis balances insulin sensitivity and strength through calcium signaling. J Clin Invest 2013; 123: 1229-1240
-
(2013)
J Clin Invest
, vol.123
, pp. 1229-1240
-
-
Funai, K.1
Song, H.2
Yin, L.3
-
6
-
-
0035038782
-
Mechanisms of nutritional and hormonal regulation of lipogenesis
-
Kersten S. Mechanisms of nutritional and hormonal regulation of lipogenesis. EMBO Rep 2001; 2: 282-286
-
(2001)
EMBO Rep
, vol.2
, pp. 282-286
-
-
Kersten, S.1
-
7
-
-
79957605136
-
Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity
-
Fu S, Yang L, Li P, et al. Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity. Nature 2011; 473: 528-531
-
(2011)
Nature
, vol.473
, pp. 528-531
-
-
Fu, S.1
Yang, L.2
Li, P.3
-
8
-
-
81855226617
-
Activating and deactivating roles of lipid bilayers on the Ca(2+)-ATPase/phospholamban complex
-
Gustavsson M, Traaseth NJ, Veglia G. Activating and deactivating roles of lipid bilayers on the Ca(2+)-ATPase/phospholamban complex. Biochemistry 2011; 50: 10367-10374
-
(2011)
Biochemistry
, vol.50
, pp. 10367-10374
-
-
Gustavsson, M.1
Traaseth, N.J.2
Veglia, G.3
-
9
-
-
0842288475
-
Ca2+ and AMPK both mediate stimulation of glucose transport by muscle contractions
-
Wright DC, Hucker KA, Holloszy JO, Han DH. Ca2+ and AMPK both mediate stimulation of glucose transport by muscle contractions. Diabetes 2004; 53: 330-335
-
(2004)
Diabetes
, vol.53
, pp. 330-335
-
-
Wright, D.C.1
Hucker, K.A.2
Holloszy, J.O.3
Han, D.H.4
-
10
-
-
79952209778
-
Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle
-
Goonasekera SA, Lam CK, Millay DP, et al. Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle. J Clin Invest 2011; 121: 1044-1052
-
(2011)
J Clin Invest
, vol.121
, pp. 1044-1052
-
-
Goonasekera, S.A.1
Lam, C.K.2
Millay, D.P.3
-
11
-
-
84859910158
-
Hsp72 preserves muscle function and slows progression of severe muscular dystrophy
-
Gehrig SM, van der Poel C, Sayer TA, et al. Hsp72 preserves muscle function and slows progression of severe muscular dystrophy. Nature 2012; 484: 394-398
-
(2012)
Nature
, vol.484
, pp. 394-398
-
-
Gehrig, S.M.1
Van Der Poel, C.2
Sayer, T.A.3
-
12
-
-
0036734611
-
The major sites of cellular phospholipid synthesis and molecular determinants of Fatty Acid and lipid head group specificity
-
Henneberry AL, Wright MM, McMaster CR. The major sites of cellular phospholipid synthesis and molecular determinants of Fatty Acid and lipid head group specificity. Mol Biol Cell 2002; 13: 3148-3161
-
(2002)
Mol Biol Cell
, vol.13
, pp. 3148-3161
-
-
Henneberry, A.L.1
Wright, M.M.2
McMaster, C.R.3
-
13
-
-
0033210772
-
Gene targeting restricted to mouse striated muscle lineage
-
Miniou P, Tiziano D, Frugier T, Roblot N, Le Meur M, Melki J. Gene targeting restricted to mouse striated muscle lineage. Nucleic Acids Res 1999; 27:e27
-
(1999)
Nucleic Acids Res
, vol.27
, pp. e27
-
-
Miniou, P.1
Tiziano, D.2
Frugier, T.3
Roblot, N.4
Le Meur, M.5
Melki, J.6
-
14
-
-
84255186061
-
The nuclear receptor PPARβ/δ programs muscle glucose metabolism in cooperation with AMPK and MEF2
-
Gan Z, Burkart-Hartman EM, Han DH, et al. The nuclear receptor PPARβ/δ programs muscle glucose metabolism in cooperation with AMPK and MEF2. Genes Dev 2011; 25: 2619-2630
-
(2011)
Genes Dev
, vol.25
, pp. 2619-2630
-
-
Gan, Z.1
Burkart-Hartman, E.M.2
Han, D.H.3
-
15
-
-
65349122785
-
Inhibition of contraction-stimulated AMP-activated protein kinase inhibits contraction-stimulated increases in PAS-TBC1D1 and glucose transport without altering PAS-AS160 in rat skeletal muscle
-
Funai K, Cartee GD. Inhibition of contraction-stimulated AMP-activated protein kinase inhibits contraction-stimulated increases in PAS-TBC1D1 and glucose transport without altering PAS-AS160 in rat skeletal muscle. Diabetes 2009; 58: 1096-1104
-
(2009)
Diabetes
, vol.58
, pp. 1096-1104
-
-
Funai, K.1
Cartee, G.D.2
-
16
-
-
0016783761
-
Energy-dependent calcium sequestration activity in rat liver microsomes
-
Moore L, Chen T, Knapp HR Jr, Landon EJ. Energy-dependent calcium sequestration activity in rat liver microsomes. J Biol Chem 1975; 250: 4562-4568
-
(1975)
J Biol Chem
, vol.250
, pp. 4562-4568
-
-
Moore, L.1
Chen, T.2
Knapp, H.R.3
Landon, E.J.4
-
17
-
-
84864705801
-
Inhibiting adipose tissue lipogenesis reprograms thermogenesis and PPARγ activation to decrease diet-induced obesity
-
Lodhi IJ, Yin L, Jensen-Urstad AP, et al. Inhibiting adipose tissue lipogenesis reprograms thermogenesis and PPARγ activation to decrease diet-induced obesity. Cell Metab 2012; 16: 189-201
-
(2012)
Cell Metab
, vol.16
, pp. 189-201
-
-
Lodhi, I.J.1
Yin, L.2
Jensen-Urstad, A.P.3
-
18
-
-
80053403320
-
Skeletal muscle triglycerides, diacylglycerols, and ceramides in insulin resistance: Another paradox in endurancetrained athletes?
-
Amati F, Dubé JJ, Alvarez-Carnero E, et al. Skeletal muscle triglycerides, diacylglycerols, and ceramides in insulin resistance: another paradox in endurancetrained athletes? Diabetes 2011; 60: 2588-2597
-
(2011)
Diabetes
, vol.60
, pp. 2588-2597
-
-
Amati, F.1
Dubé, J.J.2
Alvarez-Carnero, E.3
-
19
-
-
85018988272
-
Effect of Roux-en-Y gastric bypass and laparoscopic adjustable gastric banding on branched-chain amino acid metabolism
-
Magkos F, Bradley D, Schweitzer GG, et al. Effect of Roux-en-Y gastric bypass and laparoscopic adjustable gastric banding on branched-chain amino acid metabolism. Diabetes 2013; 62: 2757-2761
-
(2013)
Diabetes
, vol.62
, pp. 2757-2761
-
-
Magkos, F.1
Bradley, D.2
Schweitzer, G.G.3
-
20
-
-
70349326750
-
Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity
-
Fabbrini E, Magkos F, Mohammed BS, et al. Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity. Proc Natl Acad Sci U S A 2009; 106: 15430-15435
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 15430-15435
-
-
Fabbrini, E.1
Magkos, F.2
Mohammed, B.S.3
-
21
-
-
42949178538
-
Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects
-
Korenblat KM, Fabbrini E, Mohammed BS, Klein S. Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects. Gastroenterology 2008; 134: 1369-1375
-
(2008)
Gastroenterology
, vol.134
, pp. 1369-1375
-
-
Korenblat, K.M.1
Fabbrini, E.2
Mohammed, B.S.3
Klein, S.4
-
22
-
-
84873358822
-
Rab10 GTPase regulates ER dynamics and morphology
-
English AR, Voeltz GK. Rab10 GTPase regulates ER dynamics and morphology. Nat Cell Biol 2013; 15: 169-178
-
(2013)
Nat Cell Biol
, vol.15
, pp. 169-178
-
-
English, A.R.1
Voeltz, G.K.2
-
23
-
-
0022628695
-
In vivo insulin resistance in individual peripheral tissues of the high fat fed rat: Assessment by euglycaemic clamp plus deoxyglucose administration
-
Kraegen EW, James DE, Storlien LH, Burleigh KM, Chisholm DJ. In vivo insulin resistance in individual peripheral tissues of the high fat fed rat: assessment by euglycaemic clamp plus deoxyglucose administration. Diabetologia 1986; 29: 192-198
-
(1986)
Diabetologia
, vol.29
, pp. 192-198
-
-
Kraegen, E.W.1
James, D.E.2
Storlien, L.H.3
Burleigh, K.M.4
Chisholm, D.J.5
-
24
-
-
84921907646
-
Human muscle fiber type-specific insulin signaling: Impact of obesity and type 2 diabetes
-
Albers PH, Pedersen AJ, Birk JB, et al. Human muscle fiber type-specific insulin signaling: impact of obesity and type 2 diabetes. Diabetes 2015; 64: 485-497
-
(2015)
Diabetes
, vol.64
, pp. 485-497
-
-
Albers, P.H.1
Pedersen, A.J.2
Birk, J.B.3
-
25
-
-
1342325483
-
Greater effect of diet than exercise training on the fatty acid profile of rat skeletal muscle
-
Turner N, Lee JS, Bruce CR, et al. Greater effect of diet than exercise training on the fatty acid profile of rat skeletal muscle. J Appl Physiol (1985) 2004; 96: 974-980
-
(2004)
J Appl Physiol (1985)
, vol.96
, pp. 974-980
-
-
Turner, N.1
Lee, J.S.2
Bruce, C.R.3
-
26
-
-
0033939421
-
Calcium ion in skeletal muscle: Its crucial role for muscle function, plasticity, and disease
-
Berchtold MW, Brinkmeier H, Müntener M. Calcium ion in skeletal muscle: its crucial role for muscle function, plasticity, and disease. Physiol Rev 2000; 80: 1215-1265
-
(2000)
Physiol Rev
, vol.80
, pp. 1215-1265
-
-
Berchtold, M.W.1
Brinkmeier, H.2
Müntener, M.3
-
27
-
-
84870265848
-
Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals
-
Bal NC, Maurya SK, Sopariwala DH, et al. Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals. Nat Med 2012; 18: 1575-1579
-
(2012)
Nat Med
, vol.18
, pp. 1575-1579
-
-
Bal, N.C.1
Maurya, S.K.2
Sopariwala, D.H.3
-
28
-
-
84954386766
-
The CDP-ethanolamine pathway regulates skeletal muscle diacylglycerol content and mitochondrial biogenesis without altering insulin sensitivity
-
Selathurai A, Kowalski GM, Burch ML, et al. The CDP-ethanolamine pathway regulates skeletal muscle diacylglycerol content and mitochondrial biogenesis without altering insulin sensitivity. Cell Metab 2015; 21: 718-730
-
(2015)
Cell Metab
, vol.21
, pp. 718-730
-
-
Selathurai, A.1
Kowalski, G.M.2
Burch, M.L.3
-
29
-
-
79960776844
-
Skeletal muscle lipid flux: Running water carries no poison
-
Funai K, Semenkovich CF. Skeletal muscle lipid flux: running water carries no poison. Am J Physiol Endocrinol Metab 2011; 301:E245-E251
-
(2011)
Am J Physiol Endocrinol Metab
, vol.301
, pp. E245-E251
-
-
Funai, K.1
Semenkovich, C.F.2
-
30
-
-
0030969532
-
Skeletal muscle triglyceride levels are inversely related to insulin action
-
Pan DA, Lillioja S, Kriketos AD, et al. Skeletal muscle triglyceride levels are inversely related to insulin action. Diabetes 1997; 46: 983-988
-
(1997)
Diabetes
, vol.46
, pp. 983-988
-
-
Pan, D.A.1
Lillioja, S.2
Kriketos, A.D.3
-
31
-
-
0035217707
-
Skeletal muscle lipid content and insulin resistance: Evidence for a paradox in endurance-trained athletes
-
Goodpaster BH, He J, Watkins S, Kelley DE. Skeletal muscle lipid content and insulin resistance: evidence for a paradox in endurance-trained athletes. J Clin Endocrinol Metab 2001; 86: 5755-5761
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 5755-5761
-
-
Goodpaster, B.H.1
He, J.2
Watkins, S.3
Kelley, D.E.4
-
32
-
-
84857861919
-
Mechanisms for insulin resistance: Common threads and missing links
-
Samuel VT, Shulman GI. Mechanisms for insulin resistance: common threads and missing links. Cell 2012; 148: 852-871
-
(2012)
Cell
, vol.148
, pp. 852-871
-
-
Samuel, V.T.1
Shulman, G.I.2
-
33
-
-
76049092146
-
Acyl-CoA synthesis, lipid metabolism and lipotoxicity
-
Li LO, Klett EL, Coleman RA: Acyl-CoA synthesis, lipid metabolism and lipotoxicity. Biochim Biophys Acta 2010; 1801: 246-251
-
(2010)
Biochim Biophys Acta
, vol.1801
, pp. 246-251
-
-
Li, L.O.1
Klett, E.L.2
Coleman, R.A.3
-
34
-
-
84860430699
-
Lipid-induced mitochondrial stress and insulin action in muscle
-
Muoio DM, Neufer PD. Lipid-induced mitochondrial stress and insulin action in muscle. Cell Metab 2012; 15: 595-605
-
(2012)
Cell Metab
, vol.15
, pp. 595-605
-
-
Muoio, D.M.1
Neufer, P.D.2
-
36
-
-
84860482342
-
A ceramide-centric view of insulin resistance
-
Chavez JA, Summers SA. A ceramide-centric view of insulin resistance. Cell Metab 2012; 15: 585-594
-
(2012)
Cell Metab
, vol.15
, pp. 585-594
-
-
Chavez, J.A.1
Summers, S.A.2
-
37
-
-
84860483727
-
The role of endoplasmic reticulum in hepatic lipid homeostasis and stress signaling
-
Fu S, Watkins SM, Hotamisligil GS. The role of endoplasmic reticulum in hepatic lipid homeostasis and stress signaling. Cell Metab 2012; 15: 623-634
-
(2012)
Cell Metab
, vol.15
, pp. 623-634
-
-
Fu, S.1
Watkins, S.M.2
Hotamisligil, G.S.3
-
38
-
-
34248188085
-
Ca2+/calmodulin-dependent protein kinase kinase-alpha regulates skeletal muscle glucose uptake independent of AMP-activated protein kinase and Akt activation
-
Witczak CA, Fujii N, Hirshman MF, Goodyear LJ. Ca2+/calmodulin-dependent protein kinase kinase-alpha regulates skeletal muscle glucose uptake independent of AMP-activated protein kinase and Akt activation. Diabetes 2007; 56: 1403-1409
-
(2007)
Diabetes
, vol.56
, pp. 1403-1409
-
-
Witczak, C.A.1
Fujii, N.2
Hirshman, M.F.3
Goodyear, L.J.4
-
39
-
-
80052770295
-
C2 domain-containing phospho-protein CDP138 regulates GLUT4 insertion into the plasma membrane
-
Xie X, Gong Z, Mansuy-Aubert V, et al. C2 domain-containing phospho-protein CDP138 regulates GLUT4 insertion into the plasma membrane. Cell Metab 2011; 14: 378-389
-
(2011)
Cell Metab
, vol.14
, pp. 378-389
-
-
Xie, X.1
Gong, Z.2
Mansuy-Aubert, V.3
-
40
-
-
36849069450
-
Calmodulin-binding domain of AS160 regulates contraction- but not insulin-stimulated glucose uptake in skeletal muscle
-
Kramer HF, Taylor EB, Witczak CA, Fujii N, Hirshman MF, Goodyear LJ. Calmodulin-binding domain of AS160 regulates contraction- but not insulin-stimulated glucose uptake in skeletal muscle. Diabetes 2007; 56: 2854-2862
-
(2007)
Diabetes
, vol.56
, pp. 2854-2862
-
-
Kramer, H.F.1
Taylor, E.B.2
Witczak, C.A.3
Fujii, N.4
Hirshman, M.F.5
Goodyear, L.J.6
-
41
-
-
84929513535
-
Exercise ameliorates insulin resistance via Ca2+ signals distinct from those of insulin for GLUT4 translocation in skeletal muscles
-
Park DR, Park KH, Kim BJ, Yoon CS, Kim UH. Exercise ameliorates insulin resistance via Ca2+ signals distinct from those of insulin for GLUT4 translocation in skeletal muscles. Diabetes 2015; 64: 1224-1234
-
(2015)
Diabetes
, vol.64
, pp. 1224-1234
-
-
Park, D.R.1
Park, K.H.2
Kim, B.J.3
Yoon, C.S.4
Kim, U.H.5
-
42
-
-
0030971458
-
Effects of diet on muscle triglyceride and endurance performance
-
Starling RD, Trappe TA, Parcell AC, Kerr CG, Fink WJ, Costill DL. Effects of diet on muscle triglyceride and endurance performance. J Appl Physiol (1985) 1997; 82: 1185-1189
-
(1997)
J Appl Physiol (1985)
, vol.82
, pp. 1185-1189
-
-
Starling, R.D.1
Trappe, T.A.2
Parcell, A.C.3
Kerr, C.G.4
Fink, W.J.5
Costill, D.L.6
-
43
-
-
0347511829
-
Endurance capacity and high-intensity exercise performance responses to a high fat diet
-
Fleming J, Sharman MJ, Avery NG, et al. Endurance capacity and high-intensity exercise performance responses to a high fat diet. Int J Sport Nutr Exerc Metab 2003; 13: 466-478
-
(2003)
Int J Sport Nutr Exerc Metab
, vol.13
, pp. 466-478
-
-
Fleming, J.1
Sharman, M.J.2
Avery, N.G.3
-
44
-
-
14844335701
-
Effect of high-fat or high-carbohydrate diets on endurance exercise: A meta-analysis
-
Erlenbusch M, Haub M, Munoz K, MacConnie S, Stillwell B. Effect of high-fat or high-carbohydrate diets on endurance exercise: a meta-analysis. Int J Sport Nutr Exerc Metab 2005; 15: 1-14
-
(2005)
Int J Sport Nutr Exerc Metab
, vol.15
, pp. 1-14
-
-
Erlenbusch, M.1
Haub, M.2
Munoz, K.3
MacConnie, S.4
Stillwell, B.5
-
45
-
-
84920003046
-
Compartmentalized acyl-CoA metabolism in skeletal muscle regulates systemic glucose homeostasis
-
Li LO, Grevengoed TJ, Paul DS, et al. Compartmentalized acyl-CoA metabolism in skeletal muscle regulates systemic glucose homeostasis. Diabetes 2015; 64: 23-35
-
(2015)
Diabetes
, vol.64
, pp. 23-35
-
-
Li, L.O.1
Grevengoed, T.J.2
Paul, D.S.3
-
46
-
-
0020597859
-
Phosphatidylserine decarboxylase is located on the external side of the inner mitochondrial membrane
-
Zborowski J, Dygas A, Wojtczak L. Phosphatidylserine decarboxylase is located on the external side of the inner mitochondrial membrane. FEBS Lett 1983; 157: 179-182
-
(1983)
FEBS Lett
, vol.157
, pp. 179-182
-
-
Zborowski, J.1
Dygas, A.2
Wojtczak, L.3
-
47
-
-
84904854824
-
The concentration of phosphatidylethanolamine in mitochondria can modulate ATP production and glucose metabolism in mice
-
van der Veen JN, Lingrell S, da Silva RP, Jacobs RL, Vance DE. The concentration of phosphatidylethanolamine in mitochondria can modulate ATP production and glucose metabolism in mice. Diabetes 2014; 63: 2620-2630
-
(2014)
Diabetes
, vol.63
, pp. 2620-2630
-
-
Van Der Veen, J.N.1
Lingrell, S.2
Da Silva, R.P.3
Jacobs, R.L.4
Vance, D.E.5
-
48
-
-
33847216159
-
Essential role of insulin and insulin-like growth factor 1 receptor signaling in cardiac development and function
-
Laustsen PG, Russell SJ, Cui L, et al. Essential role of insulin and insulin-like growth factor 1 receptor signaling in cardiac development and function. Mol Cell Biol 2007; 27: 1649-1664
-
(2007)
Mol Cell Biol
, vol.27
, pp. 1649-1664
-
-
Laustsen, P.G.1
Russell, S.J.2
Cui, L.3
-
49
-
-
0027468258
-
Immunological characterization, lipid dependence, and subcellular localization of CTP: Phosphoethanolamine cytidylyltransferase purified from rat liver. Comparison with CTP: Phosphocholine cytidylyltransferase
-
Vermeulen PS, Tijburg LB, Geelen MJ, van Golde LM Immunological characterization, lipid dependence, and subcellular localization of CTP: phosphoethanolamine cytidylyltransferase purified from rat liver. Comparison with CTP: phosphocholine cytidylyltransferase. J Biol Chem 1993; 268: 7458-7464
-
(1993)
J Biol Chem
, vol.268
, pp. 7458-7464
-
-
Vermeulen, P.S.1
Tijburg, L.B.2
Geelen, M.J.3
Van Golde, L.M.4
|