Activation of hippocampal BDNF signaling is involved in the antidepressant-like effect of the NMDA receptor antagonist 7-chlorokynurenic acid

Brain Research

Volumn 1630, Issue , 2016, Pages 73-82

  Li, Cheng Fu ^a   Chen, Xue Mei ^a   Chen, Shao Mei ^a   Mu, Rong Hao ^b   Liu, Bin Bin ^b   Luo, Liu ^b   Liu, Xiao Long ^b   Geng, Di ^b   Liu, Qing ^b   Yi, Li Tao ^b  

^a Traditional Chinese Medicine of Xiamen Hospital   (China)

^b HUAQIAO UNIVERSITY   (China)

Author keywords

7 Chlorokynurenic acid; Brain derived neurotrophic factor; Depression; Toxicological evaluation

Indexed keywords

7 CHLOROKYNURENIC ACID; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; K 252A; MITOGEN ACTIVATED PROTEIN KINASE; POSTSYNAPTIC DENSITY PROTEIN 95; PROTEIN KINASE B; SYNAPSIN I; 7-CHLOROKYNURENIC ACID; ANTIDEPRESSANT AGENT; KYNURENIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL EXPERIMENT; ANTIDEPRESSANT ACTIVITY; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; FEEDING; HIPPOCAMPUS; LATENT PERIOD; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; DEPRESSIVE DISORDER; DISEASE MODEL; DRUG EFFECTS; INSTITUTE FOR CANCER RESEARCH MOUSE; KIDNEY; LIVER; MALE; MENTAL STRESS; METABOLISM; PATHOLOGY; PRECLINICAL STUDY; RANDOMIZATION; UNCERTAINTY;

ANIMALS; ANTIDEPRESSIVE AGENTS; BRAIN-DERIVED NEUROTROPHIC FACTOR; DEPRESSIVE DISORDER; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; HIPPOCAMPUS; KIDNEY; KYNURENIC ACID; LIVER; MALE; MAP KINASE SIGNALING SYSTEM; MICE, INBRED ICR; RANDOM ALLOCATION; RECEPTORS, N-METHYL-D-ASPARTATE; STRESS, PSYCHOLOGICAL; UNCERTAINTY;

EID: 84962289392     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2015.11.005     Document Type: Article

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