Anti-inflammatory and anti-allergic effects and underlying mechanisms of Huang-Lian-Jie-Du extract: Implication for atopic dermatitis treatment

Journal of Ethnopharmacology

Volumn 185, Issue , 2016, Pages 41-52

  Chen, Yunlong ^a   Xian, Yanfang ^a   Lai, Zhengquan ^a   Loo, Steven ^a   Chan, Wood Yee ^a   Lin, Zhi Xiu ^a  

^a Prince of Wales Hospital   (Hong Kong)

Author keywords

Atopic dermatitis; Degranulation; Huang Lian Jie Du extract; Lyn; MAPKs; NF B

Indexed keywords

ANTIALLERGIC AGENT; ANTIINFLAMMATORY AGENT; BETA N ACETYLHEXOSAMINIDASE; CHINESE DRUG; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HUANG LIAN JIE DU; INTERLEUKIN 1BETA; INTERLEUKIN 4; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN KINASE LYN; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; CYTOKINE; HERBACEOUS AGENT; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NITRIC OXIDE; NONSTEROID ANTIINFLAMMATORY AGENT; ORENGEDOKU TO;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; ATOPIC DERMATITIS; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG MECHANISM; HISTAMINE RELEASE; IMMUNOREACTIVITY; IN VITRO STUDY; INTRACELLULAR SIGNALING; MAST CELL DEGRANULATION; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; TH2 CELL; ANIMAL; CELL SURVIVAL; CHEMISTRY; DERMATITIS, ATOPIC; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOUSE; PHOSPHORYLATION; RAW 264.7 CELL LINE;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL SURVIVAL; CYTOKINES; DERMATITIS, ATOPIC; DRUGS, CHINESE HERBAL; GENE EXPRESSION REGULATION; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; NF-KAPPAB INHIBITOR ALPHA; NITRIC OXIDE; PHOSPHORYLATION; RAW 264.7 CELLS;

EID: 84962233378     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2016.03.028     Document Type: Article

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