15d-PGJ2 alleviates ConA-induced acute liver injury in mice by up-regulating HO-1 and reducing hepatic cell autophagy

Biomedicine and Pharmacotherapy

Volumn 80, Issue , 2016, Pages 183-192

  Chen, Kan ^a   Li, Jingjing ^a   Li, Sainan ^a   Feng, Jiao ^a   Wu, Liwei ^a   Liu, Tong ^a   Zhang, Rong ^a,b   Xu, Shizan ^a,b   Cheng, Keran ^a,c   Zhou, Yuqing ^a,c   Zhou, Shunfeng ^a,c   Wang, Fan ^a   Dai, Weiqi ^a   Xia, Yujing ^a   Lu, Jie ^a   Zhou, Yingqun ^a   Guo, Chuanyong ^a  

^a TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

^c THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

Author keywords

14 prostaglandin J2; 15 Deoxy 12; Autophagy; Concanavalin A; HO 1; Nrf2

Indexed keywords

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CONCANAVALIN A; HEME OXYGENASE 1; INTERLEUKIN 1BETA; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA; 15-DEOXYPROSTAGLANDIN J2; NFE2L2 PROTEIN, MOUSE; PROSTAGLANDIN D2; TUMOR NECROSIS FACTOR;

ACUTE HEPATITIS; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; AUTOLYSOSOME; AUTOPHAGY; CELL DEATH; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; ENZYME ACTIVATION; HISTOPATHOLOGY; LIVER CELL; LIVER HISTOLOGY; LIVER INJURY; LIVER PROTECTION; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; ACUTE DISEASE; ANALOGS AND DERIVATIVES; ANIMAL; BAGG ALBINO MOUSE; CELL NUCLEUS; DISEASE MODEL; DRUG EFFECTS; HEPATITIS; INJURIES; LIVER; METABOLISM; PATHOLOGY; PHAGOSOME; ULTRASTRUCTURE; UPREGULATION;

ACUTE DISEASE; ANIMALS; AUTOPHAGY; CELL NUCLEUS; CONCANAVALIN A; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; HEME OXYGENASE-1; HEPATITIS; HEPATOCYTES; INTERLEUKIN-1BETA; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIVER; MALE; MICE, INBRED BALB C; NF-E2-RELATED FACTOR 2; PHAGOSOMES; PROSTAGLANDIN D2; REACTIVE OXYGEN SPECIES; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 84962221147     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2016.03.012     Document Type: Article

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